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What if I have AIDS? When will AIDS be completely cured?

What if I have AIDS? When will AIDS be completely cured?

Hi, I'm a doctor who works with HIV at the CDC, let me give you an answer.

Since AIDS was first discovered in the United States in 1981, more than 40 million people worldwide have been infected with HIV, and 35 million people have died of AIDS or AIDS-related illnesses; in China, 958,000 people are currently registered as HIV-infected, and about 260,000 people have died of AIDS or AIDS-related illnesses.

So many HIV-infected people hope that one day AIDS can be completely cured, after all, this is a bomb on the body; there are also those "itchy" people, also hope that AIDS can be completely cured, so that they can rest assured boldly "play".

But, unfortunately, AIDS cannot be cured at this time. In fact, not only is it not currently curable, but it will not be completely cured for many years to come, at least.

  • In March 2019, Nature published a major paper reporting that a London man may have been cured of AIDS after receiving a stem cell transplant. This is the second patient in the world to be successfully cured of HIV after the "Berlin Patient".
  • On March 10, 2020, The Lancet HIV, a subspecialty of The Lancet, published online details of the London patient's treatment and identity. The results also mean that after 30 months of observation, the "London patient" has been cured of HIV, with no virus found in his blood, lymphatic or intestinal tissues.

There have been two complete cures for AIDS worldwide, one for the "Berlin Patient" and one for the "London Patient".

(Timothy Brown, Berlin patient)

How were they completely cured?

The "Berlin Patient" and the "London Patient" were both infected with HIV and leukemia at the same time. Scientists transplanted blood stem cells from a person with a CCRδ32 allele deletion, and miraculously, not only was their leukemia cured, but their AIDS was cured as well. Miraculously, not only was their leukemia cured, but their AIDS was also cured.

So can this case be generalized? Unfortunately, no! At least not with current technology!

On the one hand, the bone marrow transplant must be a successful match, and on the other hand, there must be a deletion of the CCR5δ32 allele, which is very difficult to obtain.The CCR5δ32 allele is missing in only a small percentage of Europeans! Technology is one aspect, but so is the cost. The cost of this treatment is quite high and not affordable for the average family.

Can AIDS currently be treated?

Can! Currently, HIV can be inhibited by antiviral drugs, which can reduce or eliminate the destruction of human immune cells by HIV, so that the human body has a normal immune function, but it is necessary to take medication for life, and it is necessary to take the medication every day at regular intervals!

Because the AIDS virus in the human body and the human body's genetic integration to form HIV-DNA viral reservoir, the viruses in the viral reservoir can not be completely eliminated, when there is no drug inhibition will be re-replicated, the recent new coronavirus pneumonia infected patients discharged from the hospital after the cure "re-positive" phenomenon there may be a similar viral reservoir.

But in July 2019, more than 30 researchers at Temple University and the University of Nebraska Medical Center succeeded in eradicating the HIV-DNA viral reservoir from the DNA of lab rats, an important step toward a successful cure for AIDS.

(Professor Howard Gendelman, University of Nebraska)

What are you gonna do?

The fact that you are infected with AIDS cannot be changed, and AIDS cannot be cured completely, so you can only face it correctly and accept it.

First, you must take the medication every day on time, can not stop taking the medication privately, there may be some side effects of the drug, but generally speaking appeared in the first three months of taking the drug, three months after the body can basically tolerate some of the adverse effects of the drug.

Secondly, keep a positive mindset and face it correctly, you don't have to be afraid because correct treatment is not going to affect your life expectancy.

Third, stop the medical advice, on time physical examination, test CD4T cells, chest CT, blood, liver and kidney function.

Fourth, actively exercise and pay attention to diet and nutrition.

Finally, you don't have to have any psychological pressure or burden, you can think of it in another way, many people die prematurely because they think they are in good health, smoke and drink heavily, and overdraw their lives. You know you suffer from the disease, you may pay more attention to some of the problems of life, will not go to the overdraft of their own bodies, but will be more loving their own bodies, perhaps you will live a more "healthy".

The above is my answer, if you have AIDS related problems, you can follow me to private message advice, you can also give me a like forward it, thank you!

Read a lot of comments below the question, a lot of basic knowledge I will not state, let me give you the most concerned about the focus of the place, if you have AIDS you do what to do with the question.

National Intervention 90-90-90 Strategy for HIV/AIDS

I'm also a doctor in Infectious Disease Control at the Centers for Disease Control and Prevention.The country is currently targeting HIV and AIDS(HIV is the virus, AIDS is the disease)The strategy is a 90-90-90 strategyThat is, 90% of surviving HlV/AIDS patients are detected, 90% of diagnosed HIV/AIDS patients receive standardized HAART, and 90% of treated HIV/AIDS patients achieve viral suppression.This is a strategy not only for the country but also for the world.What do we need to be clear about in response to the 90-90-90 strategy?

the first percent90%

At the end of 2017 the country is currentlyA total of 134,512 new cases of HIV/AIDS have been detected, of which more than 95% were contracted through sexual transmission. The national goal is to accelerate 90% of infections What is the purpose?

There is a very important concept in our field of preventive medicine.Early detection, early diagnosis, early treatment. There is a certain latency period in the development of AIDS.If the disease is not detected in time and develops into AIDS, especially in patients with Kaposi's sarcoma and Pneumocystis carinii pneumonia, the mortality rate is very high, with a mortality rate of 50 percent in one year of the course of the disease, and close to 100 percent in five years of the course of the disease. This is not an alarmist talk, if you don't believe me, you can read the information.

We ourselves have been diagnosed all over the early detection in theory we should be happy that we have not been delayed until the end of the disease. What about the remaining 10% after we ourselves are 90% detected?

What it means also means that there is still a percentage of patients who do not realize that they are infected.If you are already a person living with HIV the first thing you need to do which is your obligation includes:

1. Informing the fact of infection or disease to other persons who have sexual relations with them;

2. You also need to inform your doctor of the facts during your visit;

3. Not to infect others in an extreme way by maliciously retaliating against society;

Doctors never, ever discriminate against infected patients.We, as individuals, need to fulfill our obligations in a timely manner while enjoying the AIDS treatment care provided by the State.Inform people in close contact with you who may be infected in a timely manner, so that the majority of people are not left in the dark and become 10% undetectable.! Causing great damage to their health later in life.

Second 90%

We expand on 3 levels:

1. i.e. accept 90% HAART, what is HAART?

HAART (Highly Active Anti-Retroviral Therapy) is a specific treatment for HIV administered by our clinicians. Its purpose is to maximize the inhibition of the unlimited replication of HIV in our body, to prevent HIV from indiscriminately destroying our immune system; in this way, to maintain our normal quality of life; to reduce the possibility of various opportunistic infections due to the collapse of the body's immune system at a later stage; and to reduce the transmission of subsequent AIDS, and even through the transmission of mother-to-child transmission to our offspring.

Opportunistic infections: refers to some pathogens with weak pathogenicity, which cannot cause disease when the body's immune function is normal, but when the body's immune function is lowered, they take advantage of the situation and invade the human body, leading to a variety of diseases. For example, serious tuberculosis, herpes simplex virus, fungal infections.

So knock on wood here regulated HAART is vital and not based on something as simple as taking your medication on time!!!!


The greatest difficulty in the treatment of AIDS is viral drug resistance.

HIV is a highly mutated RNA virus with properties different from DNA its reverse transcriptaseThe lack of corrective features can easily lead to random mutations that can occur on their own.. Viruses replicate at a high frequency in our bodies, and integration between viral and host DNA in different populations due to the pressure of immune clearance, theIn particular, we are now emphasizing that unregulated HAART is a major cause of viral resistance.


2. What constitutes standardized HAART, or highly active antiretroviral therapy?

Currently, there are more than 30 types of international anti-retroviral drugs in six categories, and each regimen has advantages and disadvantages. The standardized selection of drugs needs to be based on the following principles:

  • Note the difference between adult dosage and child/infant dosage

  • Pay attention to the adverse effects of drug toxicity, especially for hepatic and renal injuries, abnormalities in glucose and lipid metabolism should be monitored to prevent the occurrence of serious consequences;

  • Be aware of contraindications and interactions between combinations of drugs;

There are more than thirty different medications that can't be listed here, so let's use the domestic Zidovudine as an example:

zidovudineThe adult dose is 300mg/dose taken twice dailywhereasFor newborns, the dosage is 2mg/kg four times a day.Adverse effects include myelosuppression, severe anemia or neutropenia, as well as prolonged discomfort and possibly even lactic acidosis or hepatic steatosis; special attention should be paid to itsNot to be used in combination with stavudine

The above is the drug profile of Zidovudine, which should be taken in strict accordance with the instructions and doctor's recommendations.

Secondly are you a special population? There are special treatment reference programs for breastfeeding women, adolescents, and co-infection with HBV. Treatment needs to be chosen carefully.


3. Monitoring of antiviral therapy

As the saying goes, if you know the enemy and you know yourself, you will never be in danger. We can't assess whether the enemy has been eliminated by us or not when we aim to kill them in the microcosm from a macrocosmic perspective.. at this timeDuring the course of HAART treatment, we need to perform regular clinical evaluations and laboratory tests.The aim is to assess the effectiveness of the drug interventions, to detect adverse effects of the antiviral drugs, to identify the development of viral resistance, and to change the drugs if necessary to ensure the success of the antiviral treatment.

  • viral load testing

When conditions permit, adding that you are asymptomatic with HIV, and by asymptomatic we mean in the latent stage of HIV, testing is recommended once a year, as well as we are talking about during the course of HAART therapy or prior to adjusting the treatment regimen we need to do viral vector load testing as well, in order to get early on whether or not there is a virologic failure.

Virologic failure in this context means that our plasma HIV viral RNA is persistently greater than 200 copies/ml after we have been treated with HAART medication suggesting that our treatment is not working well.

At this point it is necessary to evaluate our patient's treatment ofIs there resistance to treatment adherenceWhether there are drug-drug or even drug-food interactions.

Treatment adherence here is the determining factor in the success of our treatment.


  • CD4+ T-lymphocyte assay
Why do I need CD4+ T lymphocyte monitoring?
HIV primarily infects immune T-cells that have CD4+ glycoprotein markers on the cell surface. Knowing the amount of CD4+ in the plasma provides the clearest picture of the current state of our immunity and makes it easier to see how the disease is progressing;
For example, a CD4+ count of <200/ul is considered to be in the late stages of AIDS. The patient's CD4+ count slowly decreases over an average of 8 years during the asymptomatic phase of infection, from 800 to 350/ul.

1. In general CD4+ testing is determined by the clinician. Asymptomatic HIV-infected patients with >350 CD4+ T lymphocytes/ul need to be tested every 6 months;

2. And we emphasize that standardized HAART patients need to be monitored every 3 months during the first year of treatment, and every 6 months for patients who have been treated for more than one year and are stable.

3. ForPatients with adequate viral suppression and long-term stable CD4+ T-lymphocyte counts after HAART, CD4+ T-lymphocyte counts in the range of 300-500 cells/uL are recommended to be tested every 12 months, and CD4+ T-lymphocyte testing may be performed selectively in patients with >500 cells/uL.


proactive interest in monitoring viral loads and CD4+ T-lymph levels.One's own initiative to cooperate, initiative to listen to the doctor's instructions, timely attention to their own body within the microscopic changes, in order to justify and fight with HIV to continue a lifelong battle!!!!

Otherwise it's not going down without a fight our doctors disagree! Your family and even others who care for you disagree even more !!!!.


Third 90%

Only early detection of the 90% of patients who are already infected with HIV/AIDS and early intervention with the right antiretroviral regimen for the diagnosed 90% can tend to or exceed the third 90%That is, 90% of HIV/AIDS patients achieve viral suppression!!!!

summarize

Please keep in mind:: Please keep in mind:: Please keep in mind:: It's important to say it three times:

The availability and use of antiretroviral drugs has now transformed AIDS into a chronic disease that can be treated but for which a complete cure is currently elusive.

The national level is strategically deployed in accordance with the 3 90% to minimize the HIV/AIDS cohort only to the greatest extent possible.

From our personal point of view, we should take the initiative to face the disease correctly and formally HAART treatment, only in this way can the current limited medical level to the most will be converted to HIV/AIDS disease we call chronic disease, maximize life expectancy, improve the quality of life!


We have written a Q&A article, and we sincerely hope that the above content can help you in your daily life as well as at the level of medical consultation. If you find it helpful, you can forward it to your platform for other people's reference, and if you have any questions, you can add attention to the private message contact for consultation. These are today's answers. Thank you for listening!

Brother, never, ever be cynical. Don't mess around. Nourish yourself slowly, in case a special drug is developed in the future, people have to have hope. This disease is not the same as cancer. Reduce your antibodies, get well and you can see hope. There are so many beautiful girls waiting for you to pursue.

HIV is a viral disease and follows the basic laws of viral diseases.

For one thing, viral diseases are essentially less likely to be cured, as is usually seen with HBV, chickenpox shingles.

Secondly, maintain good habits and mentality, there is also the possibility of self-healing, clinical mostly see HBV turn negative, there are also reports of HIV turn negative.

Thirdly, the ultimate goal of the virus is to embed the DNA code of the virus into the DNA code of human beings to improve the genetic structure of human beings and ultimately to promote human evolution, which is equivalent to the transgenic technology, just for a longer period of time. So.

It is also a contribution to the evolution of man.

It's not curable yet! If you are infected, take your medication! AIDS is now a chronic disease, everyone can get it, it's just not the same disease! Would you be a millionaire if you didn't have it? If not, what's the difference if you have it? The only difference between you and someone else is that you take more pills every day! Sooner or later, everyone passes away! In this limited life, make yourself happy 😁! Just try not to have any regrets! None of us can control the length of our lives! Then grasp the width of your life! May you be happy every day! Go for it (ง -̀_-́)ง! Friend.

You first need to actively cooperate with the treatment, do not break the can, do not hate fate is unfair to you, there are many ways to get AIDS, here do not comment, must be reported to the local government, the health department, do not pass on people, now AIDS is not incurable, listen to the doctor's words, to improve their own immunity, and most of all do not retaliate against the community to do something extreme, actively cooperate with the doctor will certainly be improved. will improve, at present a complete cure has not been heard of, I wish you good luck!

At present, mankind has reached a new historical stage in the treatment of AIDS. It can be said that the name of AIDS as an incurable disease can be declared to be over.

Most AIDS patients are able to receive free treatment provided by the State. Many anti-AIDS drugs, mainly antiretroviral drugs, are very effective in inhibiting the spread and replication of HIV. A friend of Mr. Han's who works in Beijing's Ditan Hospital (a nationally renowned hospital specializing in infectious diseases) told me that if AIDS is detected early, treated in a timely manner, blocked adequately, and medications are taken in a standardized manner, patients with AIDS are able to achieve the same expected state of health and life expectancy as normal people. Some patients with good health can even have their HIV load reduced to 0. For such patients, we can already call them clinically cured. Of course, there is still the possibility of relapse.

For weight, if you have AIDS, you should go to a nationally designated infectious disease hospital as soon as possible for consultation and standardized treatment. Early detection, early diagnosis and early treatment is the only shortcut to complete treatment of AIDS.

Although we are not yet in a position to anticipate the time when we will be able to treat AIDS at its root, I think that this time is approaching us at an accelerated pace through the continuous efforts of all mankind.

Thanks for the invite.

I. There are cases of cure for AIDS.

Yes, there are now two cases of cure worldwide.

First case:

In early 2007, Brown received a transplant of 61 bone marrow stem cells, transplant surgery soon, Brown felt very relaxed, weight gain in the continued, look better, and the body of the virus did not "make waves".

Example 2:

London, March 10, The Lancet HIV announced the emergence of the world's second "AIDS cure" patient, his name is Adam Castillejo, this year's 40 years old, was detected in 2003 infected with HIV, and in 2012 began to take antiretroviral drugs. He received a stem cell transplant in 2016 for Hodgkin's lymphoma. He has been off the medication for 30 months and has no HIV in his blood.

Second, you'll live for years without a cure.

Nowadays, the medical level is gradually improving, and patients can also live to a normal life expectancy after active treatment, especially standardized antiviral treatment, opportunistic infections are controlled, viruses are suppressed, and immunity is gradually improved.

III. Optimism, common sense and hard work in life

So, you are perfectly capable of living a normal life, the key is to fill your insides with sunshine.

Hopefully, this will help you.

Note: Images are from the internet, please contact to remove if there is any copyright issue.

In fact, suffering from AIDS and does not mean death, on the contrary, many people with the disease began to rethink life, after all, can only be alone to go forward, many people with AIDS will think about the meaning of life, as a result, many people's souls have been cleansed, have lived a very meaningful.

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AIDS can't be cured, but it doesn't affect life expectancy



AIDS is not currently curable, but for most people with AIDS, getting a normal life expectancy is still not a problem.

Once AIDS is still relatively difficult to treat the disease, but Chinese scientists invented the "cocktail" therapy, can be for different periods of time, the use of different drugs, so many people, although not cured, but will not affect the life expectancy, coupled with a number of special means, as long as the AIDS people do not hide from the couple each other, still can be In addition, there are some special means, AIDS patients can still give birth to healthy babies and have a perfect life as long as they do not hide it from each other.

People with AIDS should not be discriminated against



Many people think that AIDS people "indiscreet", in fact, many people suffer from AIDS and sex has nothing to do with, dental repair, blood transfusion and even injections, may be infected with AIDS, there are a lot of people, that is, we often hear of AIDS children, they are because their mothers or fathers have AIDS, was born to suffer from such a "terminal illness". They are born with this "terminal illness" because their mothers or fathers have AIDS, and it is not their wish to be stigmatized, so in fact, many of them are very pitiful.

Thanks to the advancement of science, it is believed that AIDS can definitely be conquered in the future, and this day will not be too far away.

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With the development of medical technology, especially the development and use of antiretroviral drugs, AIDS has now become a chronic disease that is treatable but difficult to cure.

If you have AIDS, you have to face the reality, don't run away, accept the regular examination and treatment, and follow the doctor's instructions to take medication on time. Respect and love yourself, develop good living habits, and build up confidence in life. There are individual cases of self-recovery all over the world, and I believe that in the near future, human beings will be able to overcome AIDS, and turn chance events into inevitable results.

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