Hydroquinone, or hydroquinone, can be used to treat melasma as its main effect is to inhibit tyrosinase activity and regulate the metabolic process of melanocytes, thus producing skin discoloration.

Hydroquinone treatment for melasma usually starts at a low concentration (2%) and is used once a night, with good results seen after 4 to 6 weeks of treatment.

However, hydroquinone is irritating, and possible side effects include contact dermatitis and permanent white spots. Therefore, in recent years, fewer and fewer countries and regions have used hydroquinone as a whitening ingredient, and the 2007 version of China's cosmetic hygiene standard has included it as a prohibited substance in skin care products, and it can only be used in prescription drugs.

Hydroquinone cream is contraindicated in people:

(1) Patients with hypersensitivity to the ingredients in hydroquinone cream;

(2) Children under 12 years of age;

(3) Pregnant women.

Because chloasma is related to a variety of factors, including staying up late, sun exposure, endocrine disorders, oral contraceptives, etc., no matter any treatment method, it must be combined with the improvement of lifestyle habits, otherwise there is a certain possibility of recurrence.

There are many other ways to treat chloasma, including fruit acid, micro-needling, photoelectric treatment and internal and external application of traditional Chinese medicine, etc. Comprehensive therapy is the only way to receive the best results.

You can click into my homepage and go to the free column - "Melasma Fine Science Articles" to check out the details.

I'm @DrHuangBeautyClass and I'm here to answer your questions.

Hydroquinone cream can indeed get rid of melasma, which is a potent tyrosinase inhibitor that reduces melanin production. Since melasma is a disease of abnormal active melanocytes in the skin caused by a combination of endocrine, genetic, ultraviolet and emotional factors, it is also easy to rebound after using hydroquinone if these causes are not adjusted.

Here's a look at it.

How does hydroquinone get rid of melasma?

"Hydroquinone contains a potent inhibitor of tyrosinase, which can affect the conversion of dopa into melanin and block the production of melanin, thus achieving the effect of whitening. According to research findings, the use of hydroquinone cream in clinical treatment of melasma, 4 to 8 weeks can be reduced.

Hydroquinone was first discovered in 1936 when it was found to change the color of animal hair.By 1939, hydroquinone whitening had also been observed in humans: black workers who used gloves containing hydroquinone derivatives "decolorized" the skin on their hands and turned white.

In that case, wouldn't hydroquinone be used to whiten the skin in minutes? Actually not. Hydroquinone effect is good, but there are many side effects, the current domestic cosmetics is banned, only in the form of drugs. As a topical medicine, hydroquinone cream has significant therapeutic effects on melasma, freckles, inflammation and post-surgical hyperpigmentation spots. Cosmetic ingredients in which hydroquinone is found are illegal to use.

It turns out that "hydroquinone" is irritating and has strong side effects. Studies have found that hydroquinone has a clear cytotoxicity, if used in excess, it has a strong corrosive effect on the skin and mucous membranes, and can inhibit the central nervous system or damage the skin function of the liver.

Is there a rebound with hydroquinone?

The factors leading to chloasma are complex. Usually, there is a chloasma susceptibility gene in the patient's body, and under the influence of ultraviolet rays, sex hormone disorders, negative emotions and other factors, the melanocytes in the body will be abnormally active, leading to the accumulation of melanin in the skin.

Hydroquinone inhibits tyrosinase activity, but this is not permanent. Once discontinued, it is prone to recurring without the cause of melasma being lifted.

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There are many familiar whitening and lightening ingredients, 377, arbutin, niacinamide, VC .....

But when your need to lighten your spots is so urgent that you go to the dermatologist, the only topical lightening product they will prescribe is hydroquinone, an ingredient that has received mixed reviews, with some people praising its power and others spouting off about its ferocity, so what the heck is hydroquinone?

Hydroquinone is a skin discoloring agent and is currently the most effective ingredient in the skin community for removing blemishes.

Its mechanism of action is to produce reversible skin discoloration by inhibiting the oxidation of the enzyme that converts tyrosine to dihydroxyphenylalanine and inhibiting other melanocyte metabolic processes. (Reversible skin discoloration...are you excited?)

But you can't have it both ways. Hydroquinone is irritating, and some people's skin may become red and itchy if they don't tolerate it.

Although the effect is good, do not be greedy. And pay attention to its use, requirements, need to be very standardized.

😘How to use it and what to look for is here:

• Before normal use, be sure to do a skin test on a small localized area to see if you are allergic before normal use.
  

• Hydroquinone is used to avoid light, so use it at night before bed.
  
• After cleansing your face at night, start with a water lotion and then finish with a hydroquinone cream.
  
• Hydroquinone is irritating, it is normal that there may be slight redness and itching when using it. Pay attention to sunscreen during the day ah, sunscreen is very important, not sunscreen will be used in vain.
  

Thank you for being so nice and complimenting me 😊

I've used it. It didn't work.

First of all, we need to look at what spot where the main growth, about how long, the depth of how, some in the local and some in the internal is the situation of the blood is not that a cream can remove chloasma, and is not recommended to inhibit or lead-mercury overload of spotlighting products, indicators do not treat the root of the follow-up may also grow more powerful, targeted internal and external use will be better, I hope to help you, and the best thing is that you can send a photo of your face to help you look better, and I hope to help you. If you can send a face photo to help you look at it will be better to give appropriate advice, I hope you are getting more and more beautiful ❤️

Any creams to get rid of spots or ointments to get rid of spots will contain more or less hormone products, so they are not safe. You can try herbal mask to get rid of spots, the effect is really good.

I feel that the choice of spot removal methods or to be careful, the experience of the past, I have a variety of methods, a lot of products have been used, laser, traditional Chinese medicine have been used, the results are not no use, are rebound, the money has not been less spent, thankfully, the final conditioning good.

But carcinogens

Chloasma requires a combination of medication, internal conditioning plus external application, and the effect of using one type alone is not obvious. When treating chloasma, you have to distinguish which type you belong to, and then apply the right medicine to get a good result.

I've used it. It works a little, but then it grows back.