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Canton Pharmaceuticals released research results that drinking Wanglaoji can extend life expectancy by 10%, is this credible?

Canton Pharmaceuticals released research results that drinking Wanglaoji can extend life expectancy by 10%, is this credible?

The mildest thing I've picked to use to express my attitude towards this story is just four characters, with letters and numbers and Chinese characters: rip the G8's balls off!

Let's not talk about what the hell this Wang Lao Ji is, herbal tea I only recognize Gadobao. Just from a methodological point of view, how can it come to this conclusion?

In order to conclude that the life expectancy of users has been extended by 10 Paisons, from the current scientific and technological level of mankind, there are no more than two ways to do so: one is to conduct a long-term tracking study to statistically compare the difference in life expectancy between users and non-users; and the other is to find out the life enhancement effect of the Wanglaoji drink from the perspective of life expectancy mechanism.

The first method is quite time-consuming and has strict or even demanding requirements for the selection of the sample to be followed, in other words, a large sample and a long period of time. Even so, only "possible" conclusions can be drawn, which can easily be criticized and disproved. For example, after hundreds of years of research on the hazards of cigarettes and a large population of smokers, an organization has concluded through research that smoking a cigarette reduces life expectancy by about 10 minutes, but this is only a claim that has not been recognized by academics, and it is at most used by individual smoking cessation organizations.

The second approach is limited to the fact that mankind's knowledge of the mechanisms affecting longevity is extremely limited, so there are only theoretical possibilities for research on this topic, but not realistically implementable. This is like as long as human beings build a "Dyson Sphere" (Dyson Sphere) to encircle the sun, can be close to 100% utilization of the sun's energy, the next 5,000 years of human beings are afraid that it is not possible to master this technology.

Let's go back and look at the methodology used to arrive at the "10% longer" life expectancy advocated by the Chairman of GPHL. According to the disclosure in the press release of GPC, the following is true:There is no specific method published, no specific experimental research data and argumentation process, and I don't even know what kind of control group is set up. If this is all feasible, I can confidently announce that based on the methodology published by GNP, eating my boogers can extend my life by 20%, no, 64%.

The method is simple, choose wolves to do the experiment, cool enough! Raise a group of wolves to mix some boogers in their food every day, compare the wolves in the wild natural state, the experimental group of booger-eating wolves can surely extend their lifespan by 64% compared to the control group of wolves who didn't eat boogers.

See, I've disclosed more detail than the rat experiments in the broadsheets.

Why? Look at the chart below.A originally private brand Wanglaoji trademark looting for state-owned, and later authorized to go out by others to spend a huge cost of painstakingly managed to make a province of Guangdong herbal tea products to the national market, and forcibly recovered the looted trademark to make the same red can packaging of the Huayao Group. Shamelessness is a person's personality traits, across time and across the context of the stability of psychological qualities, in the plunder of other people's brands and markets shamelessly, then the lack of data, methodology, and the process of argumentation of the dubious animal experiments advocating the extension of the life of 10 Parson's life, to make such a shameful thing, Chairman of the Board of Directors of Guangzhou Pharmaceuticals, and you are the only one.

I have personal reservations about this result.I am not very clear about the specific ingredients of Wanglaoji drinks, let alone understanding the mechanism by which these ingredients work on the human body.

The life span of a person is influenced by many factors and it is understood that theChina's average life expectancy in various historical periods was: in the Eastern Han Dynasty, 22 years; in the Tang Dynasty, 27 years; in the Song Dynasty, 30 years; in the Qing Dynasty, 33 years; and in the Republican Period, 35 years. In 1985, China's per capita life expectancy was 68.92 years, and in 2010, it exceeded 70 years.

Old age, sickness and death are natural norms, in addition to economic development, social peace and stability, disease is the biggest cause of death, and few people die without illness, so the level of medical technology to a certain extent affects the average life expectancy of people.

Back to the thing about Wanglaoji improving human longevity.

1. In a two-year mouse survival experiment, it was found that the herbal tea experimental group of mice was superior to the control group. This experiment, I personally thought, only showed that herbal tea might be beneficial in improving the survival of mice and might be beneficial to the health of mice.

2, animals and human beings are still very different, in animal experiments on the problem, can not be copied to the human body, in other words, animal experiments show that the survival period extended by ten percent, can not be determined in this way in the human body can also be extended by ten percent, hasty to conclude that the first of this conclusion is not a scientific, rigorous attitude.

3, the life expectancy of human has reached more than 70 years, far from only 2 or 3 years of life expectancy of mice, in this 70 years of wind and rain, we need to drink how many years of Wanglaoji, 10 years, 20 years, 50 years? How much do we drink every day? What is the amount that is good for the human body, theWill long-term consumption cause health hazards instead?, there are no numbers for any of these, and there will be no numbers to illustrate them.

4. Scientific and rigorous statistics on life expectancy can only be obtained from the previous review of the results, because the human 70 years or more statistics, not a generation can be counted. Therefore, the study of the benefits of a certain drug, health product or beverage on the human body (or life expectancy extension) is not as simple as a simple pat on the head, because, such a study is lengthy, and the design of a control group, and toIt's at least 80 years away.But this, how do you experiment?

5. In fact, for this experiment, there is absolutely no need for Wanglaoji executives to state the conclusion that it can prolong life, as long as they state the results of animal experiments, the public will naturally have a good judgment.And it is a bit of an insult to the public's intelligence to favor such an unorthodox conclusion of extending one's life by 10%.

The above is my personal opinion and I am not biased against Wanglaoji Company.

A family's words are not truth.

Human life expectancy is affected by many factors, and in general, it is no more than congenital (endogenous) and acquired (exogenous) factors, specifically related to heredity, gender, personality, as well as diseases, living environment, lifestyle (such as diet, nutrition, exercise, hobbies) and other factors. In fact, there are also many uncertain factors involved, which cannot be counted because the uncertainty of accidental factors is too strong.

1, genetic factors: the main factor affecting human life is heredity, human beings live and die and human genes have a close connection.

2. Lifestyle: Lifestyle includes diet, exercise and many other factors. For example, nutrition is very important for human longevity, before our country is difficult, a lot of people are malnourished, and try to find ways to supplement nutrition. At this stage, our living standards are improving, more and more people are getting rich, and the nutritional status is getting better and better, if we take in excess nutrition, it will make the human body's energy metabolism abnormal, leading to high incidence of obesity, hyperlipidemia, hypertension, coronary heart disease, diabetes mellitus, and other cardiovascular and cerebrovascular diseases. Exercise is the same, 150 minutes of moderate exercise per week is good for health, excessive exercise and no exercise is not right.

3, living environment factors: beautiful and unpolluted environment is an important condition for longevity. Here we have to say that we have encountered the haze, there is evidence that the haze directly lead to cardiovascular and cerebrovascular diseases and respiratory diseases. This year we encountered much less haze than before, take this opportunity to give the relevant departments here to praise!

4. Gender and personality factors: women live longer than men. At the same time, it is recognized that many long-lived people have the same good character, that is, open-mindedness, optimism, and goodwill to others.

Of course there are many other factors that affect life expectancy, too many to list here. But then again, do you believe that a $3 bottle of drink can give you 10% more life expectancy?

For more health information, please follow Dr. Zhang Zhiying's headline number.

This is the so-called "bricklayer", who is talking nonsense with his eyes wide open.I'll just stick up for Huang Zhenlong!

Life is a very complex organic whole, from the Qin Emperor Han Wu, the emperors began to pursue longevity and longevity, all kinds of alchemy and search for immortality, the result of Wanglaoji got out, do you believe it?

Life is unpredictable, any sudden change may lead to the interruption of life, human beings are not mice that can be kept in a bottle without being attacked by the external environment. Human Life TrajectoryintricateChangeable, a strong wind and a heavy rain, or the death of a loved one, a lover's change of heart, all may trigger the seven emotions and feelings of change and discomfort, will affect the health. Who are you to say that life extension of 10%, this claim itself is bullshit, let alone whether it is rigorous or scientific.

Conclusion: It's not believable, just take it as a joke. Moreover, Wanglaoji, like other sweet drinks, is not low in sugar, and drinking more of it can be detrimental to your health, so don't expect to live a long life.

Does this 863 program research really exist?

The company said it was a national 863 project, which is not exactly making things up, but it is also exaggerating the results of the study.

This 863 project really exists, and its full name is "Functional Food Safety Evaluation and Functional Factor Key Detection Technology", which is completed by a number of research institutions.

And this herbal tea research mentioned by the president of Wanglaoji in the news is just a sub-project of this 863 program. So, his statement is actually just borrowing the 863 program to fool the public.

As for how this project is actually done and what the experimental conditions are, there are no published papers or public details available, only some broken information from the information posted on the Internet, which is actually an animal experiment, done with rats, and all the results are based on the data obtained from the rats.

What's wrong with this study?

From the information so far, this study is only a very preliminary experiment, and its results are not credible, at least not to show that people can live longer after drinking Wanglaoji.

First, it is only an animal experiment. Animal experiments are in fact very preliminary research, but also need to go through the human body research, clinical demonstration of the effectiveness of the application to people. Because the gap between animals and human beings is very large, animals eat the effect, does not mean that people will also get the same effect.

Secondly, the results of any one experiment are done under specific experimental conditions. At present, the enterprise did not publish specific data and argumentation process, how to do, how much to drink, are not clear, the credibility of the experiment is also very difficult to ensure that the average person to drink how much, how to drink it? There is also no operational significance at all.

Want some herbal tea?

If you like the drink, it's still okay to drink it occasionally.

However, it should be reminded that herbal tea is not a healthy drink. As with all sweet drinks, herbal tea is high in sugar, and a can of herbal tea usually has about 25 grams of sugar in it. It is important to know that the World Health Organization (WHO) recommends that our intake of added sugar should not exceed 50 grams per day, and it is best to keep it within 25 grams per day.

In other words, the sugar content of one can of herbal tea has already touched the red line of the World Health Organization. If you really drink more of it, I guess it will only be detrimental to your health, and longevity? Dream on.

So, from a health point of view, people should still drink less.

The claim, which comes from a statement made by the chairman of the Guangzhou Pharmaceutical Group at an international science and technology conference in Guangzhou in December 2017, is that the results of a study by the National 863 Program showed that drinking Wanglaoji can extend life expectancy by about 10 percent.

The 863 project mentioned is a national 863 project jointly undertaken by GPHL and Guangdong Center for Disease Control and Prevention: "Functional Food Safety Evaluation and Functional Factor Key Detection Technology" (June 2011-June 2013).In June 2013, GPHL made a press conference specifically on the project, mentioning the relevant results: "The statistical survival time of the test group of 2.90g/kg BW female rats consuming Wanglaoji herbal tea in the test was 708.2 days. project, mentioning the relevant results: "The statistical survival time of the test group of female rats consuming Wanglaoji Herbal Tea 2.90g/kg BW in the test was 708.2 days, while the statistical survival time of female rats in the control group was 675.1 days, which was 33.1 days higher, and the difference was obvious."

Folks, now see, if drinking Wanglaoji prolongs life expectancy, then we are talking about the life expectancy of rats here. Pull out a calculator and do the math, it's a 33.1 day improvement from the control average survival time of 675.1 days, that's 4.9%, not 10% either. If 4.9% can be rounded down to 10%, then 10% can continue to be rounded down to 100%.

Because of the chairman's remarks, the "863" program has been blackened enough! Many people questioned why the national research funds are used to study what is not good, have to go to study this? In fact, from the title of this 863 project, this experiment is not used to evaluate Wang Lao Ji can extend life, should be evaluated the safety of this herbal tea. From the results of this rat experiment, the safety of herbal tea is not a big problem, at least there is no major toxicity, otherwise you will see the experimental group of rats die early. As for the rats that drank the herbal tea lived 4.9% more, is this difference significant? One needs to look at the specific statistical results, not from the data provided in this news story anyway.

Because of its good sales, Wanglaoji should be regarded as a popular beverage. It seems that Guangzhou Pharmaceuticals is not willing to report too much on why "863" wants to do this safety study. In fact, this is because the use of traditional Chinese medicine in this popular drink has caused many professionals to question the safety of such a study. Although the rat experiment did not see the safety problem, but if very pedantic report this test, in marketing may instead have a negative impact: many people who drink herbal tea will suddenly be shocked: it turns out that Chinese medicine as a drink there is this potential danger? What if the test is not sensitive enough to detect all the dangers?

Popular things are not necessarily healthy, such as the flu is unhealthy; popular beverages do not have to be healthy, such as Coca-Cola, and its health hazards are increasingly being emphasized. In order to increase the taste of herbal tea, added sugar, as long as a can of Wanglaoji every day, the dietary guidelines for the daily share of sugar intake is basically going to run out, if you eat some other sweets to burst the table. And this health risk of sugar, in animal testing can not necessarily react out.

Wanglaoji herbal tea has a traditional Chinese medicine: Xia Ku Cao, and Xia Ku Cao in the clinic has Xia Ku Cao caused allergy reports. For example, a woman took Xia Ku Cao cream, the next day the whole body itchy, skin red pimples, stop taking 2 days after the symptoms subside, the woman then take Xia Ku Cao cream, the same day in the afternoon and soon appeared rash and other symptoms, after stopping to take and subside (1). Of course, can not be because of Xia Gu Cao will cause some people allergic to say that it is poisonous, but at least show that this drink is not suitable for everyone to drink, even if it really can make the rat life extension 4.9%.

References:

1. Han, Ming-dao. Two cases of allergic reactions to Xia Gu Cao. Shanghai Journal of Traditional Chinese Medicine. 1983;3:028.

Recently, Li Chuyuan, Chairman of GPHL, said at the Fortune Global Forum, "The research results of the National 863 Program show that drinking Wanglaoji can extend life expectancy by about 10%.

On December 5, Wanglaoji's official microblogging site released a relevant message, saying that at a healthcare industry forum in China, Li Chuyuan, chairman of Guangzhou Pharmaceutical Group, said that according to the results of a study conducted by the National 863 Program, drinking Wanglaoji can extend life expectancy by about 10 percent.

According to the understanding, in January 25, 2011 the national 863 plan project - "functional food safety evaluation and functional factor key detection technology" in Guangzhou to start, and Wanglaoji Herbal Tea was selected for the 863 plan.

The news quickly caused a heated discussion among netizens, and many people issued a skeptical voice, drinking Wanglaoji can prolong life? Just kidding.

The GuangDong Group released a message on December 6, indicating that the conclusion was reached through a two-year safety experiment on 576 rat samples, "The experiment found that the survival rate of rats in the experimental group of Wanglaoji Herbal Tea was better than that of the control group, showing that long-term consumption of Wanglaoji Herbal Tea can extend the life span of animals."

Wanglaoji's official microblog posted that the news of "10% life extension" was highly recognized by Yin Ye, president of Shenzhen Huada Genetics Co.

In the face of Wanglaoji's claim, Yin Ye published a microblog on December 6 to respond, courtesy nod are fired, although also drink Wanglaoji, but does not mean to endorse this conclusion.

In response to Yin's courtesy nod, a word-shy Wang also commented.

Drinking Wanglaoji can extend life by 10%, obviously there is no scientific basis. Blame Wanglaoji was born at the wrong time, if it is in ancient times, it is not likely that any one who is bent on seeking immortality will believe it.

I always think that the best beverage advertisement in China is Wanglaoji's, and I believe we all know it very well - "Fear of fire, drink Wanglaoji", right?

The smartest thing about this advertisement is that it does not indicate that it can solve the problem of fire, but that it can solve the psychological problem of "fear of fire".

And, the extension of life mentioned in this article seems different to me.

It's not about solving the problem of whether or not you can improve 10%, it's about solving the psychological problem of wanting to live longer.

This, just my personal opinion, that's all.

Canton Pharmaceuticals released research results that drinking Wanglaoji can extend life expectancy by 10%, is this credible?

Credibility needs to be traced back to its roots.

"Drinking Wanglaoji regularly improves your life expectancy by up to 10%." What's going on?

The so-called research results claimed by GuangDong are a sub-project of the 'Functional Food Safety Evaluation and Functional Factor Key Detection Technology', a National 863 Program project launched in 2011.

After research from June 2011 to June 2013, the project published its milestones in June 2013.

In January 2016, in the "Wanglaoji Herbal Tea National 863 Program Breakthrough Scientific Research Achievements Release and the Establishment of Guangzhou Wanglaoji Health Research Institute Conference", Guangzhou Pharmaceuticals claimed that the subject group referred to the requirements of the U.S. FDA standards, and through the safety experiments on the 576 rat samples for a period of two years, it was found that the survival rate of rats of the experimental group of Wanglaoji Herbal Tea was better than that of the control group. The survival rate of rats in the experimental group of Wanglaoji Herbal Tea is better than that of the control group, showing that long-term consumption of Wanglaoji Herbal Tea can prolong the life of animals.

Recently, Li Chuyuan, chairman of the Board of Directors of Guangdao Pharmaceuticals, claimed at the Fortune International Science and Technology Brainstorming Conference that the "national program research" showed that "drinking Wanglaoji regularly improves life expectancy by up to 10 percent", which is just a reissue of the previous "results". This is merely a reissue of the previous "results".

functional food

A new term has emerged here:Functional foods.

What are functional foods?

Guangzhou Pharmaceuticals claimed that the study was based on US FDA standards, but neither the FDA nor the WHO has a definition of functional foods.

In other words, the so-called functional food is an internationalUnofficial term.The definitions that can be found refer to certain foods that, in addition to their basic nutritional functions, have a potentially positive effect on health promotion and disease prevention.

Of course, in China, since functional food can be the subject of the National 863 Program, it should be the official scientific term, right?

Unfortunately, it is also difficult to find it on the official website of the State Food and Drug Administration (SFDA).P.S By the way, the search engine on the official website of the CFDA is probably produced by Snail Technology.

There is an official definition of the term "health food":

This also means that it is interesting that the national 863 program is using "wild words" instead of the official terminology for its research.

Functional Food Safety Evaluation and Functional Factor Key Detection Technology

Then look at, GuangDong claimed to come to the conclusion of WangLaoJi life extension 10% of the national 863 program this project, the research purpose is two: one is, evaluation of the safety of the wild road functional food; two is, find these functional food to play the function of which factors, and how to test them.

Wanglaoji is one of the many food products selected for this research program. Moreover, what GuangDong is keen on and takes great pains to claim repeatedly is not the conclusion of the study's purpose, but the "life-extension of 10 per cent", which is an "extraneous feature" and an additional benefit to GuangDong.

And, this claim is released in the name of a press conference or event, which is in fact suspected of violating the relevant provisions of the Advertising Law, GuangDong as well as Li ChuYuan should be penalized by the relevant regulatory authorities.

"Drinking Wanglaoji regularly prolongs life in rats by 10%.".What does it mean?

Taking a step back, even if this conclusion announced by Guangdao is true, what does it mean? Is it that people can also prolong their lives through long-term consumption of Wanglaoji?

The answer is clear, of course you can't.

Longevity studies, exemplified by studies of longevity with dietary restrictions

On the one hand, it is common sense in medical research that the results of many animal experiments cannot be extrapolated to humans.

On the other hand, there are even more dramatic differences between animal and human studies regarding longevity.

Since humans are one of the longest-lived animals and life is fragile, many factors affect longevity over the course of a long life that are difficult to control. Human longevity research can also only be conducted by human beings, and therefore it is unlikely that there will be such longevity research projects conducted across generations.

As a result, longevity research is hardly ever a large human research program, but mainly in animals, and the simpler the animal the more it is studied.

For example.The difference in results between studies of dietary restriction to extend lifespan in a variety of different animals and humans is beyond dramatic.

Beginning as early as the 1930s, scientists have been concerned that in some animals, a significant longevity effect can be obtained by restricting the diet, and synthesizing nearly a century of research, the general results can be summarized as follows:

By restricting the diet here, we mean showing the total intake of energy without causing malnutrition.

Overall, without causingMalnutrition.Dietary restrictions can prolong a variety of organisms, including yeast, worms, and fruit flies,Mean and maximum life span of rodents and monkeys, andReduce the incidence of major diseases.

However, the phenomenon of life extension is not found in humans. Of course, it is also true that in humans it has been found that it is possible to reduceIncluding diabetes, cardiovascular disease and cancerThe risk effect of the

How can this phenomenon be explained?

From an evolutionary perspective, the greatest significance of animal life is the continuation of life's existence, which includes the survival of the individual and the continuation of the species through reproduction.

These two types of survival can have different "strategic choices" in different environments.

Animals living in harsh environments that are not conducive to individual survival tend to reproduce earlier and faster; otherwise, most of them would probably die before they could reproduce, and longevity would have no significance for the continuation of the species. On the contrary, animals living in relaxed environments tend to live longer.

In fact, this phenomenon exists in humans as well, albeit largely intentional.

This has also been confirmed by animal experiments, especially in nematodes.

Studies have identified multiple genetic variants and signaling pathways in which dietary restriction leads to increased longevity, which will not be repeated here.

Wanglaoji is toxic and reduces life expectancy?

Since Wanglaoji's study used rats, whereas dietary restriction to extend lifespan in rodents mostly uses mice.

Though not identical, both are rodents and have a greater degree of comparability.

So, if, comparing a restricted diet with drinking Wanglaoji, the former can extend life by 30 to 50%, while Wanglaoji is only 10%, does this lead to the conclusion that Wanglaoji is poisonous, and that drinking Wanglaoji regularly can shorten human life?

Apparently neither can they.

Just as, it cannot be said that regular drinking of Wanglaoji can prolong life.

Even though, the findings about Wanglaoji are true.

The experiments are real, the data are real, and the conclusions are real.

It's really funny!

If I were the boss of Coke, I wouldn't have done the rat experiment, I would have used famine refugees! Drinking Coke will definitely prolong your life by more than 50%!

Like Wanglaoji, what's Coke's magic formula for prolonging life?

--Super duper sugar.

Sugar is a great life-supporting drug for a nutrient-poor organism.

If you want to do experiments that are informative to consumers nowadays, you should at least choose to feed the rats into a state of over-nutrition first, with fatty liver and three highs, before experimenting whether drinking Wanglaoji is effective or not.

I guess the news back then was, "One drink and you're dead."

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