In today's life, many people face more or less problems with joints, bones and cervical vertebrae, which may be treated with the use of chondroitin aminosugar.

Ammonia chondroitin is also considered a drug, and more attention must be paid to the dosage, so how much ammonia can actually be taken in a day?

Based on most of the aminos products on the market we can find that the basic aminos contain 1500 mg per capsule, so depending on the weight of most adults, you only need to take 1 or 2 capsules a day.

In order to prevent the excessive loss of calcium, promote bone growth and increase bone density, ammonia is added with a large amount of Casein Phosphopeptide and Calcium Carbonate. However, if these two ingredients are present in large quantities in the body and you don't drink a lot of water, it's very likely that kidney stones will be induced.

In the repair of joint damage, the active ingredients inside the ammonia sugar, such as chondroitin sulfate and ammonia sugar, its ratio is a golden ratio, if too much intake not only will not play a role in promoting the repair of joints, and may even damage the joints, aggravate the metabolic burden of the body.

To summarize, when taking Ammonia Sugar, you must pay more attention to the dosage and do not overdose. It is recommended that when joint damage occurs, go to the hospital for systematic diagnosis, and then cooperate with the doctor to carry out active treatment, follow the doctor's instructions, and firmly control the dosage, do not rush, or you may lose more than you gain.

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Aminosugar, also known as D-glucosamine, is one of the essential nutrients for the formation of chondrocytes and a basic component of joint fluid.

make a distinction

There are two general types of aminoglycans: aminoglycans sulfate and aminoglycans hydrochloride. I have had patients use both types of aminoglycans, and the efficacy is almost the same. However, I found that Aminosulfate Hydrochloride has more side effects than Aminosulfate Sulfate. Mainly in the stomach pain and discomfort and other symptoms. This is also consistent with the results of our domestic clinical trials. Internationally, Ammonia Sulfate is the mainstay, so I still recommend patients to apply Ammonia Sulfate.

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Principle of action of Aminosugar

Aminosugar has an obvious effect on repairing cartilage, promoting the formation of joint fluid, effectively inhibiting the inflammatory process in the joints, and enhancing the immune function of the joints. Especially for the treatment of rheumatoid arthritis, the effect is obvious. In recent years, the application of aminosugar in the treatment of osteoarthritis and rheumatoid arthritis is very popular. Whether it is a big hospital or a rural hospital doctor, when encountering patients with arthritis, they will tell to apply the ammonia sugar treatment. Aminosugar is a purely natural substance extracted from marine organisms and is harmless. So it can be taken for a long time.

side effects

This is because some aminos still have some side effects when taken in excess because they contain more sodium. It has also been suggested that long-term use may increase the risk of diabetes.

dosage

It has been proved that the daily intake of 1000 to 1500 mg has an obvious effect on repairing cartilage, promoting the formation of joint fluid, effectively inhibiting the process of inflammation and enhancing the immune function of joints. A course of treatment of 3 months is preferable, do not apply for too short a period of time, that will not have a significant effect. It can be reapplied at an interval of 2 months. By the way, the treatment of arthritis with aminosugar is only one of many treatment methods, we should not expect too much from the treatment of one medicine. The treatment of arthritis should be a multifaceted combination of treatment is good.

Conclusion: you can eat this stuff, but you probably won't have cartilage for as much of it as you'd like.

Glucosamine (Glucosamine) full name D-glucosamine, also known as glucosamine, glucosamine, glucose is a hydroxyl group of glucose by the amino group after the replacement of compounds, belong to the monosaccharide components, can be extracted from the shells of crabs and shrimps. It was first discovered in 1823 by French scientist Ogier (odier) in the crustacean shell extraction.

Aminosugar is an important part of the very hydrophilic proteoglycan, one of the important nutrients in the formation of cartilage cells, so many people say it can repair cartilage sells, there are many other similar products on the market, the most common is Vitonin, thiamine chondroitin and so on.

In fact, there is not enough evidence to show that it is effective in humans.

The National Institutes of Health on (NIH) initiated and organized a large-scale randomized double-blind controlled trial where they recruited 1,584 knee osteoarthritis patients divided into three groups to take three times a day, with five possibilities for what to take: vitexin, chondroitin sulfate, vitexin plus chondroitin sulfate, cilastatin, and a placebo.

It was found that whether the vitamins were taken alone, chondroitin sulfate alone, or both together, the percentage that was effective was no different from the placebo.

This suggests that vitex actually has no effect and that the pain relief felt by those taking it is only a placebo effect. Therefore, the NIH does not recommend vitex for joint care and pain relief.

Of course, it's safe for you to take aminos properly. However, it doesn't have the effects you'd expect such as repairing cartilage and benefiting knee injuries.

My personal experience shows that very useful, I ten years ago degenerative osteoarthritis, orthopedic surgeon recommended, ammonia sugar, low content of domestic is also very expensive, my sister bought in the United States for me to serve, the immediate effect, downstairs knee pain, never broken, served to today, I went to the field, a few days did not serve, immediately knee pain, and then go home to serve after a long period of time to serve, I have only long-term service.

[Glucosamine], should be of great concern to many people, especially middle-aged and elderly people with osteoarthritis. Although there is no accurate survey, it is true that many middle-aged and elderly people, especially women, are taking this drug for a long time. Therefore, I will answer the question directly first, and then I will briefly talk about it later.

The U.S. National Library of Medicine gives dosage recommendations, as shown below:

Translation is probably:

For Glucosamine, you have to live with 1500mg a day. you can take 1500mg all at once, or you can take 500mg orally 3 times a day, 500mg at a time.

It can be taken alone or with chondroitin sulfate, 400mg of chondroitin sulfate once, 2-3 times a day.

Authoritative studies [1-2] have also found that, in order to be therapeutically effective, a certain dose must be taken: a minimum of 1500 mg of glucosamine sulfate and 800 mg of chondroitin per day (see references below).

Above, are the recommendations of authoritative international studies on the dosage of Aminosaccharides.

Beyond that, a few more personal remarks:

For middle-aged and older people with osteoarthritis, many are recommended to take glucosamine. In reality, glucosamine sulfate is just a [raw] material for synthesizing the structure of articular cartilage and that's it. While it's true that cartilage wears out in people with osteoarthritis, it's not true that the raw material we eat is necessarily used to synthesize articular cartilage. And with so many joints throughout the body needing cartilage, the little bit of raw material we eat can't be precisely applied to the exact area of damage to repair the damaged cartilage.

In addition, people with osteoarthritis have severe localized wear and tear and hyperplasia and actually have poorer circulation. It is not optimistic how much of the medication taken is actually transported by the bloodstream to the site of injury.

And the studies on it are a bit messy, ranging from those suggesting that it does nothing after taking it to those suggesting that it's a bit better than a placebo.

That's why it's so intriguing to see the opinion of the leading international UpToDate clinical advisor on aminosugar:

Glucosamine sulfate and chondroitin will not be routinely recommended for all patients with osteoarthritis, but we do not discourage patients from taking them if they are very eager to do so.

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1. Lee YH, Woo JH, Choi SJ, et al. Effect of glucosamine or chondroitin sulfate on the osteoarthritis progression: a meta-analysis. Rheumatol Int 2010; 30:357.
2. Hochberg MC. Structure-modifying effects of chondroitin sulfate in knee osteoarthritis: an updated meta-analysis of randomized placebo-controlled trials of 2-year duration. Osteoarthritis Cartilage 2010; 18 Suppl 1:S28.

Does Amino Sugar work?

This debate has been going on for a long time, and is not limited to doctors, but even among patients. It is all about knee pain, not necessarily a disease! There are causes of knee pain ranging from cartilage degeneration to meniscus injury. Even if they are both degenerative cartilage injuries, the severity of the condition and the length of the history are different, and different results may occur with the same medications and dosages. It is also necessary to take into account individualized differences such as age, gender, weight, living environment and labor intensity, so the phenomenon of some people taking it effectively while others have no effect.

What does Ammonia cure?

Aminosugar's main role is to repair cartilage, accurately speaking is to repair the lesions of minor cartilage damage or degeneration, for the middle-aged and elderly patients with degenerative changes in the knee joint is effective, like meniscus injury and other diseases almost no effect. Knee osteoarthritis (severe deformity, bone hyperplasia, joint space is obviously narrowed, lower limb force line abnormality, etc.) more serious cases, aminosugar is also "unable to help".

How do you use ammonia to make it work?

1. Adequate

In the country, the ammonia sugar is included in the drug to be managed, the amount of use has strict instructions. According to the big data research shows that the intake of ammonia sugar should be between 1500mg-2000mg, too little, the clinical effect is poor, too much or have side effects now risk, some research shows that too much intake of ammonia sugar for a long time, can lead to necrosis of pancreatic cells, induced diabetes. Below 1500mg is not as good as not eating, spending money and no effect.

2. Long-term

The effect of Ammonia Sugar is not visible for a short period of time, and in the vast majority of cases, the clinical effect will be seen only after at least 4 weeks, therefore, it is incorrect to stop taking the drug after 1-2 weeks thinking that it is not effective. If you have been taking the drug for more than 3 months and still have no effect, it is recommended to find an orthopedic surgeon for a definitive diagnosis and to change to another treatment method.

Finally, it is important to note: Ammonia is only a medication for the treatment of degenerative knee joints and is not a substitute for other medications and treatment options, which you need to clearly understand.

I am a national senior dietitian: Hu Anyun. I have been engaged in the health management of chronic diseases since 2008.

The WHO standard for supplementation with aminosugars is.

1500mg/day is the recommended dosage after 30 years of age. The joints are not diseased. Maintenance only.

2000mg/day is the basal dose. Note that it says "basal". In other words. The dosage of Ammonia Sugar should be adjusted according to different medical conditions.

Because of this. That's why a lot of people are taking aminoglycans. Some work. Some don't. Ammonia supplementation. The content is the key.

The full name of Aminosugar is D-glucosamine, a monosaccharide component that is one of the important nutrients for the formation of cartilage cells. Aminosugar can be extracted from shrimp and crab shells and is a water-soluble proteoglycan now widely used in the prevention and treatment of osteoarthropathy.

Medical research has found that the human body lacks of aminosugar will lead to the occurrence of various osteoarthropathies, and the loss of aminosugar probably begins when a person is thirty-five years old, aminosugar is the invitator of the joint cavity, not only inhibit inflammatory reaction of non-specific factors, relieve pain, and harmful enzymes in the joint cavity, improve the joints and the body's immunity, through the aminosugar brought about by the enhancement of immunity, it is an important prerequisite for the elimination of inflammation in the joints. The improvement of immunity brought about by ammonia is an important prerequisite for eliminating joint inflammation.

There are several types of aminoglycans, such as hydrochloric acid-based aminoglycans versus sulfate-based aminoglycans. The absorption of aminosaccharides by human cartilage is mainly mediated by sulfate, and relatively speaking, sulfate aminosaccharides are more easily absorbed than hydrochloride aminosaccharides. Ammonia is a slow-acting ingredient, and if taken for a long period of time, the body absorbs excessive sodium, potassium, and chloride ions that can damage the liver, kidneys, and other internal organs. So taking Ammonia Sugar involves a question of dosage.

For adults, the total daily intake of Ammonia Sugar is controlled below 2000mg, which is fine. Of course, each person's situation is different, the need to use a different amount of ammonia for cervical spondylosis, lumbar spondylosis, knee osteoarthritis, osteoporosis, osteoporosis, necrosis of the femoral head, bursitis mandatory chiropractic, frozen shoulder, tennis elbow, tendonitis, lumbar muscle strain, etc. have good results. Through anti-inflammatory, repair, bone nourishment, calcium supplementation, rehabilitation and other steps, it can slowly repair the bone damage and help bone and joint to restore health. As long as you don't overdose, people who are troubled by the above diseases can take ammonia sugar, preferably ammonia sugar with sulfate root, under the guidance of a doctor.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

First of all, aminosugar has a dominant role in the health of human joints,. The human body lack of ammonia sugar will directly lead to the occurrence of various bone and joint diseases. Ammonia sugar controls the health of human bone and joint, also controls the metabolic balance of synovial membrane of articular cartilage, ammonia sugar can catalyze and replenish the synovial fluid for the human body in large quantities, and also provides enough material carrier for articular cartilage.

Aminosaccharides are found in nature, generally in animal cartilage and trachea, and in the shells of crustaceans. In fact, the amount of aminosugar contained in food is very small, and there is no way to meet the amount of aminosugar that the human body needs every day. The human body needs 800~1000mg of aminosugar a day, then you need to eat about 4 kilograms of animal cartilage, which is unrealistic.

In this case, in addition to eating more aminosugar-rich foods, exogenous supplementation of aminosugar is also needed. That is to say, we should choose the better quality and effect of the ammonia sugar products, ammonia sugar content should be more rich, or the product also contains other better nutrition for the joints. The last time I saw an advertisement on TV for Jianliduo Ammonia Sugar, there are five kinds of nutrients to replenish cartilage and protect joints. Let the joints restore health and flexibility. It seems that the effective rate is also quite high, it is a good product.