Thank you for your question.

(1) I believe everyone has seen the 2005 Spring Festival Gala program "Thousand Hands of Goddess of Mercy", which amazed millions of viewers across the country after the program was broadcast. However, did you know that 18 of the 21 performers in the show were suffering from drug-related illnesses? "Thousand Hands Guanyin" 21 actors in 18 because of drug-induced deafness, including the main performer Tai Lihua 2 years old due to high fever injection of aminoglycoside antibiotics - streptomycin lost his hearing forever.

(2) Next, a roundup of antibacterial drugs that tend to cause deafness:

(1) Aminoglycoside antibiotics: ototoxicity is the biggest adverse reaction of this type of antibiotics, due to the accumulation of drugs in the ear, can cause vestibular nerve and cochlear nerve damage, cochlear nerve damage manifested as tinnitus, hearing loss or deafness, serious permanent deafness. The incidence of hearing damage caused by aminoglycosides is in the following order: neomycin > kanamycin > amikacin > gentamicin > streptomycin > natamycin;

(2) Glycopeptide antibiotics: such as vancomycin, norethindrone vancomycin, ticlopidine, drug concentration over can lead to reversible tinnitus, deafness, hearing damage, or even permanent deafness;

(3) Other classes of antibiotics: anti-tuberculosis drugs, such as colchicine used for a long time, can appear tinnitus, hearing loss, vertigo, ear fullness, and in severe cases, can cause deafness; macrolide antibiotics, such as acetylspiramycin, can cause tinnitus, hearing loss;

(3) To summarize: 1) antibiotics with ototoxicity are mainly aminoglycosides and glycopeptide antibiotics, while other classes of antibiotics are relatively less likely to cause deafness. 2) Ototoxic drugs should be avoided, and attention should be paid to monitoring the hearing, and stopping the medication as soon as tinnitus, deafness, and other adverse reactions occur. 3) The use of ototoxic drugs should be avoided, and attention should be paid to monitoring the hearing.

I hope you find it helpful!

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Ototoxic antibacterial drugs include aminoglycosides such as gentamicin, amikacin, nertilmicin, tobramycin, streptomycin, etc. Erythromycin, a macrolide, is also susceptible to ototoxicity if the dose is too high when placed in a static drip, as well as vancomycin, a glycopeptide.

1. Antibiotics, gentamicin, kanamycin, neomycin, tobramycin, etc.

2. Anti-cancer drugs. Cisplatin, vincristine

3. Diuretics: diuretic acid, furosemide, butylurea, etc.

4. Antimalarials, quinine, etc.

5. Hydroxy acids, aspirin

6. Heavy metals, mercury, lead, etc.

1. Antibiotics, gentamicin, kanamycin, neomycin, tobramycin, etc.

2. Anti-cancer drugs. Cisplatin, vincristine

3. Diuretics: diuretic acid, furosemide, butylurea, etc.

4. Antimalarials, quinine, etc.

5. Hydroxy acids, aspirin

6. Heavy metals, mercury, lead, etc.

Aminoglycoside drugs, tetracyclines, emetanide