The montmorillonite commonly used in clinical practice is dioctahedral montmorillonite, a lamellar structure consisting of double tetrahedral silicon oxide, monoctahedral alumina, particles with a diameter of 1-3 microns, and a formula of the formulas Si8AL4O20(OH)4. The special structure has a very large surface area (about 100 m2 per gram) and therefore a very high localization capacity.

I. Montmorillonite pharmacology

Montmorillonite has a laminar structure and non-uniform charge distribution, which has a fixing and inhibiting effect on viruses, germs and the toxins produced by them in the digestive tract; it has a covering ability on the mucous membrane of the digestive tract and repairs and improves the defense function of the mucous membrane barrier against the attacking factors both qualitatively and quantitatively by combining with mucus glycoproteins each other.

II. Side effects of montmorillonite

The main side effects of Montelukast are occasional constipation and dry stools.

Montmorillonite has low side effects, mainly because it is not absorbed by the gastrointestinal tractIn the case of Beechcraft, it does not enter the blood circulation system and is excreted from the body with the digestive tract in 6 hours together with the immobilized aggressor factors. There is no change in calcium, magnesium and aluminum levels in urine and plasma after long term administration of large quantities of Beechcraft.

III. Age of use of montmorillonite

Since montmorillonite is not absorbed by the gastrointestinal tract, its safety factor is relatively high. Therefore, it is written in the dosage approved by CFDA in China:

Children:Under 1 year of age, 1 sachet daily; 1 to 2 years of age, 1 to 2 sachets daily; over 2 years of age, 2 to 3 sachets daily, all in three divided doses. Or follow doctor's advice.

As you can see from the CFDA-approved dosage, Montelukast can be used for the treatment of diarrhea in children under 1 year of age.

Four, montmorillonite use precautions

1, treatment of acute diarrhea, should pay attention to correct dehydration.

2. If you need to take other medicines, it is recommended to take a period of time apart from this product.

3, overdose, easy to cause constipation, infants and young children are especially careful.

First of all, let's popularize the concept of adverse drug reaction (ADR). Adverse drug reactions (ADRs) are harmful reactions not related to the purpose of medication, including toxic reactions, side effects, secondary reactions, allergic reactions, and after-effects, etc., that occur under normal dosage of qualified medicines. Adverse drug reactions are caused by the inherent characteristics of drugs, and any drug may cause adverse reactions. Therefore, montmorillonite, as a pharmaceutical product, certainly has the potential for adverse reactions to occur as well. In the following, we will give you a brief introduction on the characteristics of Montmorillonite, dosage and precautions for adverse reactions.

Montelukast is used as an antidiarrheal agent for acute and chronic diarrhea in adults and children. It is also used as an adjunctive treatment for painful symptoms associated with esophageal, gastric, and duodenal disorders, but it is not used as an antispasmodic. Montmorillonite has a non-uniform charge distribution and lamellar structure, which has an inhibitory and immobilizing effect on bacteria, viruses and their metabolically produced toxins in the human digestive tract, and has the ability to cover the mucous membranes of the digestive tract, which can be used to repair and improve the defense of the mucous membrane barrier against the attacking factors by binding to mucus glycoproteins, both qualitatively and quantitatively.

For Montelukast (as Simethicone), use 1 sachet of the product diluted with 50 ml of warm water. The usual dosage for children is as follows: under 1 year old, 1 sachet/day; 1-2 years old, 1-2 sachets/day; over 2 years old, 2-3 sachets/day, divided into three times, or as directed by the doctor. Adults: 1 sachet, 3 times a day. In acute diarrhea, the first dose should be doubled. Therefore, there is no age limit for the treatment of diarrhea, and the dosage and usage are appropriate for any age group.

Adverse reactions to this product are occasionally constipation and dry stools. Since this product is not absorbed into the blood circulation through the digestive tract, and together with the immobilized attack factor excreted with the digestive tract's own peristalsis, and does not change the normal intestinal peristalsis. Therefore, children can safely take Montelukast, but should be aware of the possible adverse effects of constipation caused by this product. If constipation occurs, the drug should be discontinued promptly and a physician or pharmacist should be consulted. In addition, due to the adsorption effect of this product, if other drugs are used at the same time, they should be taken at an interval of 2 hours.

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Clinical application of montelukast as adults, children diarrhea auxiliary drugs, its role is gentle, high safety, adults and children can be used without fear. But should be under the guidance of a physician for the cause of the reasonable use of drugs, so as not to delay the condition.

Montmorillonite, also known as microcrystalline kaolinite, has a strong adhesion and fixation effect on viruses, germs and toxins in the digestive tract, making germs, viruses and toxins lose their ability to cause disease, and it also covers and protects the mucous membrane of the digestive tract, repairs the damaged mucous membrane, and improves the barrier effect of the mucous membrane to toxins and germs. In addition, it also regulates intestinal flora, local pain relief, and improves the secretion and absorption of intestinal fluids and electrolytes. It is mostly used for acute and chronic diarrhea, detoxification, enteritis, irritable bowel syndrome and other diseases. A number of meta-analyses have shown that montelukast can shorten the duration of diarrhea and improve the cure rate of diarrhea by strengthening the barrier function of the intestinal mucosa and adsorbing toxins, reducing inflammation and improving the cure rate of diarrhea. Clinically, it is often used in combination with probiotic preparations with good results.

How to apply Montelukast correctly? It is recommended not to apply continuously for more than 5 days; take it on an empty stomach; it is better to take it with probiotic preparation at intervals of more than 2 hours; attention should be paid to rehydration, correction of dehydration, prevention of electrolyte disorders; it is better to drink more than 50 ml of water when taking it, which is conducive to Montelukast to play a better role.

But montmorillonite also has adverse reactions: 1. constipation, dry stools, can disappear after stopping the drug. 2. diarrhea does not relieve after taking the drug, such as diarrhea caused by food accumulation, it is more difficult to relieve after taking the drug, you should apply the drug to eliminate food. 3. abdominal pain, anorexia. But this situation is rare.

In conclusion, montmorillonite, as an antidiarrheal agent and adsorbent, not only adsorbs toxins, but also protects the intestinal mucosa. However, the treatment of the disease should be directed to the cause of the disease.

Respondent: Wu Su M.S.

Welcome to Apricot Island for more interesting health facts!

First of all, what do people need to know about medication side effects?

1 A drug side effect is a pharmacologic effect unrelated to the therapeutic purpose of the drug when administered appropriately.

2 Why do drugs have side effects? It's because drugs have low selectivity in the body, so technically, all drugs have side effects.

3 rational view of drug side effects, the role of drugs is multifaceted, minor side effects, is a normal phenomenon, do not make a fuss. Part of the side effects of drugs can be used to treat diseases, such as morphine.

Secondly, what is montmorillonite?

1 Montmorillonite, also known as microcrystalline kaolinite or microlith, is a silica-aluminate, the main component of which is octahedral montmorillonite particles with a laminar structure and non-uniform charge distribution.

2Montmorillonite has the following functions: it has strong fixing and inhibiting effects on the virus, germs and the toxins and gases produced in the digestive tract. It has a strong protective function on the mucous membrane of the digestive tract, and has the effect of balancing the normal flora and local pain relief.

3 When taken, montmorillonite is rarely absorbed into the bloodstream, so there are few side effects, and a few people will experience constipation as a side effect.

To summarize, technically any medication has side effects, and montelukast is no exception, but montelukast has relatively few side effects.

Simida chemical name Montmorillonite powder, the main component of silicon in the aluminum salt from natural minerals, after taking does not enter the blood circulation directly with the feces out of the body, so the safety of high, light side effects, children and infants can be used safely, so about its use is worth having you.

[Principle of action]

Adsorption: Extremely strong immobilization and inhibition of viruses, pathogens and the toxins they produce in the digestive tract.

Coverage: It has a strong covering ability for the mucous membrane of the digestive tract and improves the defense function of the mucous membrane by interbinding with mucous glycoproteins.

[Dosage for children]

Specification: One bag of 3g. Add to 50ml of warm water and mix well.

Under 1 year old: one sachet per day, divided into three doses;

1-2 years old: 1-2 sachets per day, divided into three doses;

Ages 2+: 2-3 sachets per day in 3 divided doses.

In acute diarrhea, double the first dose.

[Notes

1, Simethicone is indicated for diarrhea, other gastrointestinal diseases can not use this drug. For severe diarrhea, it is recommended that the drug be used under medical supervision for safety reasons.

2, can not overdose, Similac overdose can also lead to constipation adverse reactions.

3, if you need to take other oral medications at the same time, because of the adsorption effect of Simethicone, will affect the efficacy of other drugs, it is recommended that the interval of 1-2 hours or more to use the drug.

4, the newborn swallowing incoordination and sucking ability is weak, use should pay attention to more water dilution, in order to facilitate the passage of the pharynx, to avoid causing choking.

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Montelukast - antidiarrheal medication that stops diarrhea with few side effects and can be used for all types of diarrhea, for all ages, including children.

Characteristics of the action of montelukast

(1) Good anti-diarrhea effect: the special structure can have strong adsorption force on the virus, bacteria and their toxins in the digestive tract, reducing their attack on the gastrointestinal mucous membrane, thus achieving the obvious purpose of stopping diarrhea. Used for acute and chronic diarrhea.

(2) Montmorillonite can knot mucus protein while stopping diarrhea, which has a strong protective effect on the intestinal mucosa.

(3) Fewer side effects: Montmorillonite does not enter the blood circulation, and together with the disease-causing factors, it is excreted from the body with intestinal peristalsis. Therefore, it can be taken by people of all ages, and Montmorillonite can be used for children under 1 year old.

When montelukast is used in excess it can cause constipation, so when the diarrhea improves, you should stop taking it or reduce the dosage.

(4) Montelukast has a strong adsorption effect and does not enter the bloodstream through the intestinal mucosa. Therefore, when taking other drugs at the same time, it should be separated from Montelukast for a period of time in order to prevent the effect of other drugs from being affected.

(5) Note: Montelukast is effective in stopping diarrhea, but it is important to focus on treating the cause and observing for dehydration. If the diarrhea is caused by a bacterial virus, it is best to control the infection first or wait until the bowel is cleared before using antidiarrheal medication.

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Adsorbent, mucosal protector, effective antidiarrheal, recommended for the treatment of diarrhea symptoms in the guidelines for the diagnosis and treatment of acute gastroenteritis in children (European guidelines, 14th edition). Pediatric clinical side effects are common after taking from diarrhea leads to constipation, after stopping the drug can be improved.

Montmorillonite is a widely used clinical treatment for diarrhea for all types of diarrhea. Its main mechanism is to help form stools, reduce the number of bowel movements and protect the intestinal mucosa.

According to the Montmorillonite's instructions suggest that the side effect is to cause mild constipation in a few people.

It can also be taken by infants.

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The main side effects of Montelukast are occasional constipation and dry stools.

The main reason for the low side effects of Montmorillonite is that Montmorillonite is not absorbed by the gastrointestinal tract and does not enter the blood circulatory system. It is excreted from the body in 6 hours together with the fixed attack factors along with the digestive tract's own peristalsis. There is no change in calcium, magnesium and aluminum levels in urine and plasma after long-term high dose of Beechcraft.