Montelukast Sodium Chewable Tablets are used for asthma prevention, control, and the treatment of allergic rhinitis in children aged 2-14 years and should be taken as one tablet per night, chewed and swallowed at bedtime. Why should this chewable tablet be chewed? Before we answer that question, let's take a look at how chewable tablets are different from regular tablets.

Tablets (also including chewable tablets) are solid tablets made by pressing the main drug and some suitable excipients. Compared with ordinary tablets, the biggest difference between chewable tablets is that chewable tablets do not have the disintegration (breakdown) process of ordinary tablets because they are chewed and then swallowed, so there is no disintegrating agent added to chewable tablets. Because it needs to be swallowed after chewing, so the chewable tablets must have a good taste, irritation should be small, so the added flavoring agent in the chewable tablets are screened and screened, generally choose the sweet or slightly sour flavor of the flavoring agent, after chewing, it should give a person a cool sensation, and can be quickly dissolved by saliva.

Can that chewable tablet be swallowed directly? From the aspect of adverse drug reactions, it will not cause adverse reactions; however, from the aspect of drug efficacy, the efficacy of the drug will be affected. Because there is no disintegrating agent in the chewable tablets, the tablets can not be quickly broken down after direct swallowing, which will affect the absorption of the drug, will certainly affect the efficacy of the drug. Chewable tablets are chewed and swallowed, the surface area of the tablet increases, which can promote the dissolution of the drug in the body, absorption; especially for difficult to disintegrate the drug, made of chewable tablets can accelerate its disintegration, improve the efficacy of the drug. This is also an advantage of chewable tablets.

Chewable tablets are a more suitable dosage form for children, they have a good texture, they can be chewed (like candy), and some of them are made in different shapes, all of which can greatly improve a child's compliance in taking medication.

Montelukast Sodium Chewable Tablets are called chewable tablets, so of course you have to chew them. Why do you need to chew it?

Reason one:

Montelukast Sodium Chewable Tablets are mostly used as a preventive as well as therapeutic medicine for asthma in children between the ages of 2 and 15. They are mostly taken by children, and chewable tablets are usually larger than other tablets, making them more difficult to swallow, so they need to be chewed and eaten.

Reason two:

Montelukast Sodium Chewable Tablets have no added disintegrant, if swallowed, it will lead to incomplete disintegration, which will affect the absorption of the drug, and the area of absorption will increase after chewing, and the higher the absorption rate will be.

Reason three:
Montelukast Sodium Chewable Tablets have an added sweetener that is more suitable for children and tastes like a sugar tablet, which reduces children's rejection of the medication.

For the use of the medicine we have to follow the doctor's instructions and standardize the dosage.

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Why should montelukast sodium chewable tablets be chewed? I'm going to go out on a limb here and guess what the questioner is saying, the person taking this medication is supposed to be a child, and the implication of the question is that the chewable montelukast sodium tablets can be crushed up and dissolved in water? Why does it have to be chewed inside the mouth? This is a particularly interesting question, I think this parent is particularly thinking and caring about the details of medication safety, before answering this question, I want to give you a manual kudos. My answer angle will be very unique, I will analyze this particular medicine from the perspective of drug stability:

There are two dosage forms of montelukast sodium for pediatric use currently on the market, granules and chewable tablets. We carefully read the montelukast sodium granules instructions under dosage as follows: this product can be taken directly, mixed with a spoonful of soft food (such as applesauce) at room temperature or cold, or dissolved in a teaspoon of infant formula or breast milk at room temperature or cold. Do not open the pouch until you are ready to take it. Take the full dose immediately (within 15 minutes) after opening the bag. This product should not be stored after mixing with food, infant formula or breast milk until the next dose. This product should not be dissolved in liquids other than infant formula or breast milk. However, you may drink water after taking the medicine.

After reading the above usage, if you carefully study each sentence in it, you will find that the solvent in which montelukast sodium is dissolved is very special, emphasizing the fact that it cannot be dissolved in clear liquids to be taken, for example, it can not be dissolved directly in water, but it must be dissolved in translucent or opaque jams or foods, and the instruction manual does not usually explain why it is necessary to do so, but as we, as professional pharmacists, have found out that this feature, we can tell parents that this means that this drug is a light-sensitive drug, the implication being that montelukast sodium is unstable to light.

Therefore, by the same token, montelukast sodium chewable tablets should not be dissolved in water and taken, because after crushing and then stirring and dispersing or dissolving in water, it is very likely to be exposed to light decomposition or deterioration, which affects the safety and effectiveness of the drug. And directly on the inside of the mouth to chew, because the mouth is closed, it is equivalent to avoiding light environment to eat the drug. Through these interpretations above, do you think that pharmacy is sometimes very interesting.

References: 1. Drug insert for montelukast sodium granules.2 Drug insert for montelukast sodium chewable tablets.

First of all, it is clear that the dosage form of montelukast sodium chewable tablets is that it needs to be chewed, mainly considering that it is difficult for children to swallow the whole tablet, so it is made into chewable tablets for the convenience of the children to take it; at present, there are two dosage forms of montelukast sodium available in the market, namely, ordinary tablets and chewable tablets, the former is used for the people of the age group of 15 years old and above, and the latter is used for the children of the age group of 2 years old to 14 years old; the specification of this drug has three kinds of specifications which are 4mg, 5mg, and 10mg, which are used for children between the ages of 2 and 5 years, children between the ages of 6 and 14 years, and adults aged 15 years and older, respectively.

Montelukast sodium belongs to the leukotriene receptor antagonist, can effectively inhibit inflammatory secretions; the drug is mainly used to reduce perennial allergic rhinitis, seasonal allergic rhinitis caused by symptoms, as well as the prevention and long-term treatment of asthma, it can also be used to treat aspirin-sensitive asthma and the prevention of exercise-induced bronchoconstriction; the dosage of the product is relatively simple, for patients with asthma once a day at bedtime, one tablet, and for patients with allergic rhinitis can give a relatively heavy time to give one tablet. For patients with asthma, one tablet can be taken once a day at bedtime, and for patients with allergic rhinitis, one tablet can be given at a time when the symptoms of rhinitis are relatively severe.

The role of montelukast sodium in the treatment of asthma is not to replace the inhaled glucocorticosteroids (such as Cymbicort, Sulodexide, etc.), it can be used in conjunction with them, while gradually reducing the dose of glucocorticosteroids; in the use of bronchodilators (such as salbutamol sulphate aerosol, the trade name of the Ventolin) alone can not be effective in the control of asthma, the use of montelukast sodium, the improvement of symptoms, and then gradually reduce the dose of bronchodilators until discontinued. After symptoms improve, gradually reduce the dose of the bronchodilator until it is discontinued.

Montelukast sodium is well tolerated, with a common adverse reaction being thirst, and rare adverse reactions such as drowsiness, diarrhea, nausea and vomiting, increased tendency to bleed, anxiety, and hallucinations, which generally can be tolerated without stopping the drug.

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Wukong good, first of all chewable tablets after chewing the surface area increases, can promote the absorption of drugs in the body, while improving the efficacy of the drug; in addition to chewable tablets to take convenient, even in the absence of water can also be taken without delay; three for children asthma chewable tablets in general taste better easy to be accepted; four for the elderly swallowing difficulties or gastrointestinal tract is not good for the chewable tablets to avoid swallowing as well as stimulation of the gastrointestinal tract.

All in all, chewable, tasty, easy to absorb, non-irritating and convenient!

Western medicines are generally divided into general tablets. Chewable tablets. Sublingual tablets. Enteric-coated tablets. Different methods of administration have different absorption pathway effects. Montelukastna chewable tablets are chosen to be chewed and taken. It is to allow rapid absorption by the oral mucosa. Inhibit the activity of leukotriene polypeptide in bronchial smooth muscle. And achieve the therapeutic purpose.

Indications for this medicine: it is indicated for the prevention and long-term treatment of asthma in adults and children, improves chronic airway inflammation, improves lung function and controls asthma symptoms. DOSAGE AND ADMINISTRATION: It is chewed and taken. 1 time daily. Asthma patients should be taken before bedtime. Seasonal allergic rhinitis can be taken at the time needed according to your condition. Patients with both asthma and seasonal allergic rhinitis should take the medication once a night. 1 tablet (4mg) once a day for pediatric patients aged 2-5 years with asthma and/or seasonal allergic rhinitis.

My kids' primary care physician has me soak the tablets in water and melt them and give them to my kids, and it works great!