Diabetics, once you take insulin, do you have to take it for life?
Diabetics, once you take insulin, do you have to take it for life?
[Professional doctor to answer your questions
In the treatment of diabetes mellitus, many people always worry about insulin treatment, for example, think that only when the disease is serious need to play insulin; serious disease need to play four times, the disease is light only need to play once; play insulin can not be stopped, need to be injected lifelong; can be injected once a day and so on, in fact, this is a lot of patients on insulin treatment to recognize the foot caused by.
The root cause of diabetes is the inability of one's own pancreatic islet cells to secrete enough insulin, which is the vehicle that moves blood sugar into the cells to be utilized, and when there is not enough of it, it results in a large amount of blood glucose being retained in the bloodstream, thus resulting in an elevation of blood glucose. In this case, just as a project that requires 100 vehicles to complete on schedule but now has only 50 vehicles and has to extend the schedule and then call 50 vehicles from elsewhere to ensure that the project is completed within the schedule, injecting insulin directly to make up for the missing amount of insulin will make the best use of the blood glucose and the blood glucose will be reduced to a normal level.
It can be said that insulin therapy is the most direct method in all the measures to lower blood sugar, which can play an immediate effect of lowering sugar, and insulin does not need to be metabolized by the liver and kidneys, so long-term use of insulin is almost zero damage to the body. Only its use needs to be injected under the skin, which brings a lot of inconvenience to many people, and diabetic patients are often reluctant to choose insulin treatment.
Currently used insulin is categorized into rapid-acting insulin, which works immediately after injection and is mainly used to reduce postprandial blood glucose; intermediate-acting insulin, which works slowly after injection and lasts for about 12 hours, and is mainly used to solve the problem of a large difference between preprandial and postprandial blood glucose; and long-acting insulin, which works for up to 24 hours after injection, and is mainly used to reduce the overall blood glucose level of the whole day. On this basis, rapid-acting insulin and intermediate-acting insulin are often mixed together to make premixed insulin, such as 30R with 30% rapid-acting + 70% intermediate-acting, or 50R with 50% rapid-acting + 50% intermediate-acting.
Therefore, the use of different insulin is different, such as rapid-acting insulin needs to be used before three meals, intermediate-acting and premixed insulin needs to be injected twice at 8-12 hours interval before breakfast and dinner, and long-acting insulin is usually used once before bedtime, which is based on the overall condition of the patient throughout the day to determine the type and frequency of use, it is not the worse the condition needs to be used, not to use it more often the more severe the condition is.
In fact, the use of insulin treatment can directly supplement the body's lack of insulin, thus reducing the already damaged insulin secretion burden, so that it has the opportunity to get rest to avoid the further development of the damage to the pancreatic islet cells to play a certain role in protecting the islet cells to avoid the further development of the disease, it should be known that the islet cells, once damaged and dead that is, can not be regenerated.
It is also important to know that diabetes is a progressive disease, and the continuous damage and death of pancreatic islet cells is unavoidable, and the timely use of insulin treatment can slow down the progress of this process, so patients should not refuse to use it when it is needed, or take the intermittent use of insulin can also be obtained to protect the pancreatic islet cells.
Because of this, clinical often according to the patient's pancreatic islet function and blood glucose control, to take different insulin treatment program, both to achieve the purpose of controlling blood glucose, but also to obtain the effect of protecting the pancreatic islet function, the commonly used treatment programs are:
Insulin replacement program: discontinue oral hypoglycemic drugs, inject rapid-acting insulin before three meals; inject premixed insulin before breakfast and dinner, etc.
Insulin supplementation regimen: oral hypoglycemic agents during the day, long-acting insulin or intermediate-acting insulin injections at bedtime, etc.
In conclusion, insulin therapy is one of the measures for diabetes treatment, just as there are many kinds of hypoglycemic drugs, which can be chosen and replaced according to the condition, patients can also choose and replace between insulin therapy and oral hypoglycemic drugs, not that injected insulin can not be discontinued, but according to the needs of the condition.
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Diabetes is a common metabolic disease in China. After the diagnosis of diabetes, controlling blood sugar is the key, and the main ways to control blood sugar are lifestyle changes, oral medications to lower blood sugar, and insulin injections. So, do diabetic patients who have taken insulin need to take insulin for the rest of their life? Next, Medical Senlution will analyze it for you.
Which diabetics need insulin for life?
Type 2 diabetes accounts for the majority of our diabetic population. Most patients with type 2 diabetes mellitus can get smooth control of their blood glucose through dietary control, increased exercise, or the administration of necessary oral hypoglycemic agents. However, some patients, progressing to the late stage of the disease, pancreatic β-cell function is seriously defective, insulin secretion is significantly reduced, instantly given a variety of glucose-lowering drugs, glucose control is still substandard, at this time, almost the only way to control blood glucose is by supplementing exogenous insulin. Therefore, patients with type 2 diabetes mellitus who have severe defects in pancreatic β-cell function need to inject insulin for almost a lifetime.
Except for type 2 diabetes.Type 1 diabetes is also not uncommon due to the fact that type 1 diabetics have insulinβThe cell damage is severe, resulting in absolute insulin deficiency. Once diagnosed, this group of patients should be given insulin to control their blood glucose, otherwise diabetic ketoacidosis will occur frequently, and in severe cases, it can be life-threatening.
Some patients with type 2 diabetes mellitus, need to apply insulin for a short period of time, but they do not have to apply insulin for a long period of time, after the condition improves, they can switch to oral hypoglycemic drugs according to their condition. Mainly include:
Patients with rapidly increasing blood glucose have an increased risk of diabetic ketoacidosis when blood glucose reaches 16.7 mmol/L and an increased risk of hyperglycemic hyperosmolar state when blood glucose reaches 33.3 mmol/L. Therefore, in patients with rapidly rising blood glucose, insulin should be used for a short period of time to lower blood glucose in order to reduce the risk of acute complications. After the blood glucose drops to the normal range, the glucose-lowering regimen before insulin use can be resumed according to the condition.
- come upPlus diabetic ketoacidosis,Diabetic patients with hyperglycemic hyperosmolar states require aggressive management of blood glucose or they can become life-threatening. The only way to lower blood glucose in this group of patients is through insulin to prevent the onset or worsening of coma and nerve damage.
- Newly diagnosed diabetes mellitus patients with fasting blood glucose ≥11.1 mmol/L, or glycated hemoglobin ≥9%, need to be given insulin to control blood glucose to induce remission, after a period of 3 months, after blood glucose control is up to the standard, according to the condition of the disease can be adjusted to the oral medication for glycemic control, but need to closely monitor blood glucose, and again need to be used again insulin in the event of a serious elevation.
- Diabetic patients who have acute infections, undergo major surgeries, or have severe cardiac, hepatic, or renal insufficiency will also require insulin replacement therapy during the deterioration of their condition, and the treatment regimen can be adjusted accordingly when their condition improves.
In summary, lifelong insulin use is mostly seen in patients with type 1 diabetes, type 2 diabetes with severe defects in pancreatic beta cell function. Some patients with rapidly rising blood glucose, patients with diabetic ketoacidosis, hyperglycemic hyperosmolar state, newly diagnosed diabetes mellitus accompanied by severe elevation of blood glucose, and some patients with severe deterioration of the underlying disease need to be given short-term insulin to control their blood glucose, and after the condition improves, the treatment program can be changed according to the condition.
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The first thing you can say about this question for sure is that it's not necessarily true.
Diabetes mellitus is internationally categorized into 4 types , commonly Type 1 and Type 2. Type 1 diabetes is relatively rare and is called insulin-dependent diabetes. Type 2 diabetes is more common and accounts for about 85 to 90 percent of cases. This type of diabetes is also known as non-insulin-dependent diabetes.
Type 1 diabetics are those who have a severe shortage of insulin in their own bodies and must rely on exogenous insulin, hence the term insulin-dependent diabetes.
In type 1 diabetes, insulin must be injected initially and used continuously over a period of time and cannot be easily interrupted. If the control is good, the blood sugar can be maintained at a certain normal level for a certain period of time by diet control and oral hypoglycemic drugs. The use of insulin can be stopped for a short period of time.
Type 2 diabetics are known as non-insulin-dependent diabetes mellitus, mostly seen in adults after the age of 35, and can control their blood sugar within normal levels through dietary control and oral hypoglycemic drugs.
Type 2 diabetics, people with special conditions, must use insulin injections if oral hypoglycemic drugs do not work.
Most of this type of special people are overeating, especially obese people, in the early stage of diabetes, oral hypoglycemic drugs can not control blood sugar, in the injection of insulin for a period of time, through exercise to lose weight as well as dietary control, so that the blood glucose level down to within the normal range of the insulin can be stopped.
In fact, the injection of insulin is much smaller than the use of hypoglycemic drugs side effects, insulin itself is our body's own secretion of a kind of material, there is no toxicity, there is no dependence, there is no need to talk about it, only need to master the amount of use at the time of use is good.
Diabetes prevention is more important than treatment, and diabetic patients have more complications, so pay attention to healthy eating in daily life, remember to overeat, and control weight.
This question needs to be answered according to the situation, the occurrence of type 1 diabetes is due to the absolute lack of insulin, so since the diagnosis, you need to play insulin treatment for life, type 1 diabetes patients stop using insulin treatment without authorization, it may cause serious acute complications of diabetes and life-threatening. 2 diabetes occurs due to the relative lack of insulin or defective action of insulin treatment is one of the treatment options available. Insulin therapy is an alternative treatment that can be used for short or long periods of time, and is a very effective means of controlling blood glucose when oral hypoglycemic agents are ineffective or contraindicated.
Insulin regimens are divided into short-term intensive therapy and long-term therapy.
Short-term intensive insulin therapy is indicated for patients with newly diagnosed type 2 diabetes who have a glycosylated hemoglobin ≥9.0% or a fasting blood glucose ≥11.1 with symptoms of hyperglycemia in the form of triple hyperglycemia. The duration of intensive treatment is between 2 weeks and 3 months, and the goals of treatment are fasting blood glucose of 4.4-7.0 mmol/L and two-hour postprandial blood glucose <10 mmol/L. Some newly diagnosed type 2 diabetes mellitus patients can return to normal blood glucose after intensive treatment with insulin, which ameliorates the toxicity of hyperglycemia on pancreatic islet cells, and then can be followed up periodically for monitoring, and when the blood glucose is elevated again, the fasting blood glucose ≥10.1 and the fasting blood glucose ≥11.1 with the symptoms of hyperglycemia can return to normal. elevated, fasting blood glucose ≥ 7.0 mmol/L, or 2-hour postprandial blood glucose ≥ 10.0 mmol/L, it is necessary to restart drug therapy.
In addition, in the event of acute complications of diabetes mellitus or the need for surgical treatment or accompanied by serious infections, the use of glucose-lowering drugs alone, the blood glucose level is not easy to control, but also consider giving short-term use of insulin therapy, until the acute complications are under control, after surgery to return to normal, or after infection control, can be changed to medication or continue insulin therapy.
Therefore, with the exception of type 1 diabetes, which requires lifelong insulin therapy, type 2 diabetes is selective for insulin therapy, and short-term application of insulin is safe and effective.
If you are unfortunate enough to have type l diabetes, it doesn't matter if you take any kind of hypoglycemic medication, you have to take insulin, usually once in the morning and once in the afternoon. If it is a short-acting, 15 to 20 minutes before meals, as soon as you eat, you have to play, at least three times a day. Medium-acting ones are given 15 minutes before meals, morning and evening, twice a day. For long-acting, one shot a day. You must take the shot for the rest of your life. Got type 2 (ll correct representation of the symbols do not come out), some can take drugs, some 2 times a day, some 3 times a day, due to drug resistance, time is long, the effect of lowering sugar is poor, have to change the drug, some blood sugar is always up, have to increase the amount of. 2 diabetic patients, if once hit insulin, is also must be lifelong to play. Depending on the physical condition of each person, the method of playing the same as the above mentioned type 1 playing the same. If it is type 2, can not play insulin as far as possible, but the drug has toxic side effects, encountered that can not be helped. Can match with "lowering sugar Ning capsule" health care products (price is more expensive) to take, lowering sugar effect is obvious. [Invited reply]
Dietitian Sugar is here to answer your questions. Many diabetics fear insulin, not only because of the pain when the needle is stuck, but also because insulin gives a "deterioration of condition", "hit it can not be withdrawn" illusion. In fact, insulin is not so terrible, its side effects than all kinds of hypoglycemic drugs is smaller, hit the insulin is not to be hit all the time, or divided into the condition of the situation, some patients can be withdrawn from the insulin later.
Who needs insulin?
1. Type 1 diabetics.Because of the absolute lack of their own insulin, must use insulin treatment, do not play insulin is very easy to occur ketoacidosis, but type 1 patients in the condition of the "honeymoon period" can also not play insulin.
2. Type 2 diabetics whose oral hypoglycemic drugs have failed.Patients with type 2 diabetes mellitus are often characterized by insufficient insulin secretion or sensitivity, especially those using sulfonylurea agonists, which are prone to drug failure with the prolongation of the disease (gradual damage to the pancreatic islets) and have to be injected with insulin therapy. In addition, those with high blood glucose at the time of initial diagnosis and those with rapid weight loss to the point of emaciation have difficulty in controlling their blood glucose without the use of insulin.
3. Patients with severe acute complications.For example, glucose-lowering drugs should be discontinued in favor of insulin therapy in cases of infection, tuberculosis, ketoacidosis, hyperglycemic hyperosmolar states, and also in cases of stress such as surgery and trauma.
4. patients with more severe chronic complications.For example, retinopathy and nephropathy after the intermediate stage should be treated with insulin in order to avoid further deterioration of the disease and to avoid the liver and kidney side effects of glucose-lowering drugs.
5. Hyperglycemia in pregnancy or diabetes during pregnancy.Insulin therapy should be used so that pregnancy and childbirth can occur when blood glucose control is optimal, reducing various maternal and fetal health risks. Some patients with gestational hyperglycemia have their blood glucose return to normal after delivery, and diabetics may resume glucose-lowering medication after delivery as appropriate.
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Seeing this question reminds me of a common inquiry from people with diabetes: Is insulin dependent? If I take insulin, can I stop later? Regarding insulin therapy, many patients are skeptical and find it inconvenient, so let's talk about this.
Insulin therapy is an important means of controlling high blood sugar. For people with type 1 diabetes, who are unable to secrete insulin on their own, they have to rely on insulin to maintain their lives, and must use insulin to control high blood sugar and reduce the risk of diabetic complications. For people with type 2 diabetes, although they do not need insulin to maintain life, we still need to use insulin when oral hypoglycemic drugs are not effective. Therefore, at some point, especially if the disease is prolonged, insulin therapy may be the primary, or even necessary, glycemic control measure. As a patient's perspective, we must first recognize and accept the importance of insulin therapy.
So, does insulin make our bodies dependent? Is it something that once you put it on, you can't take it off? The answer is no. The so-called addiction refers to the psychological and physiological dependence on drugs caused by repeated use of drugs, which will show some uncontrollable behaviors and other reactions, while insulin is a physiological hormone secreted by our body to maintain normal blood sugar. Whether to use insulin treatment, and whether to stop or switch to oral hypoglycemic drugs to control blood glucose after a period of time depends on the patient's condition, mainly the secretion function of the patient's own pancreatic islet β-cells. type 1 diabetes mellitus patients need insulin treatment as soon as diagnosed, and need lifelong insulin treatment. type 2 diabetes mellitus patients can be considered to start insulin treatment if the effect of the combination of a large number of doses of various oral medicines is still unsatisfactory. Patients with type 2 diabetes who do not respond well to a combination of higher doses, including multiple oral medications, may be considered for initiation of insulin therapy. If pancreatic secretion is not restored after a period of time, insulin is required for long-term glycemic control. For newly diagnosed type 2 diabetic patients with high blood glucose, insulin should also be given in order to rapidly alleviate the hyperglycemic state and thus reduce insulin resistance, thus reversing the pancreatic β-cell function to a certain extent. After stabilization of blood glucose control, such patients can gradually reduce the amount of insulin under the guidance of the doctor and transition from insulin injection therapy to oral hypoglycemic therapy. In addition, short-term use of insulin to control blood glucose in some special cases, such as pregnancy and surgery, can be discontinued after these cases.
Ke Jing, Pharmacist-in-Charge, Shiyan People's Hospital
The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.
Diabetes can be categorized into type 1 diabetes and type 2 diabetes.
Type 1 Diabetes: refers to an absolute lack of insulin due to damage to pancreatic beta cells caused by autoimmune antibodies or genetic factors. What does it mean? It means being born with a problem with the pancreas functioning properly.
Type 2 diabetes: refers to a relative deficiency of insulin due to impaired insulin secretion or the body's resistance to insulin. What does it mean? Originally the pancreas was functioning normally and then for various reasons it became less able to do its job.
For type 1 diabetes, since it is an absolute insulin deficiency, treatment is based on insulin injections and there is no other better way, so long-term insulin injections are recommended.
Type 2 diabetes, because it is a relative insulin deficiency, treatment includes dietary control, exercise, medications, and insulin.
It is possible to suspend insulin therapy during insulin injections in type 2 diabetes on a case-by-case basis.
However, it is important to note that
1. If the dose of insulin is small, not exceeding 20 units per day in total, insulin can be completely discontinued at the outset and replaced by oral hypoglycemic agents.
1) In overweight and obese diabetic patients with predominantly elevated fasting glucose, biguanides or thiazolidinediones insulin sensitizers are preferred;
(2) Insulinotropic agents or α-glucosidase inhibitors are preferred in diabetic patients who are lethargic or of normal weight and have predominantly postprandial glucose elevations;
(3) When one hypoglycemic drug alone is not effective, a combination of drugs (e.g., biguanide + sulfonylurea) can be adopted, and the drug dosage should be adjusted according to the results of blood glucose monitoring.
2. If the insulin dose is too high (around 30 units), the insulin dose can be halved at the beginning and oral hypoglycemic drugs can be added at the same time, with the same principle of drug selection as above.
However, the initial reduction in dose should not be too large, and then the insulin dosage can be gradually reduced until discontinued, and the dose of oral hypoglycemic drugs can be gradually increased until the blood glucose control is satisfactory.
If this is not necessary and can be tolerated, discontinuing insulin is not recommended!
Hello! Nutritionist is quite sure that it is not. Even people with type 1 diabetes have times when they can pause their insulin injections.
The most common types of diabetes we have are type 1 and type 2. Then Nutrition will directly each give an example of Rai to illustrate the problem, as follows:
Type 1 diabetic
Mr. Lu, 23 years old, was found to be suffering from type 2 diabetes some time ago. After taking medication for a period of time, he found that his blood glucose could not be lowered. After further examination, it turned out that Mr. Lu was suffering from late-onset diabetes in adults, that is, type 1.5 diabetes. The essence is type 1 diabetes, only the onset is later.
After a clear diagnosis, Mr. Lu received intensive insulin treatment for a period of time. Later, the doctor told him that his blood glucose situation was better recently, and that his blood glucose remained stable without insulin injections, and that he might be entering the honeymoon phase of type 1 diabetes, and that insulin could be suspended.
It has been more than half a year since he suspended his insulin. Mr. Lu has been paying more attention to diet and exercise, and his blood glucose is relatively stable. Generally speaking, if you pay more attention to diet and exercise, the honeymoon period of type 1 diabetes can be extended to 1-2 years. On the contrary, if you don't pay attention to your lifestyle habits, the honeymoon period will end earlier, and then you will have to rely on insulin treatment again.
Type 2 diabetics
Mr. Liu, now 37 years old, was just diagnosed with type 2 diabetes when his fasting blood glucose was 12.5 mmol/L and he was fat. Later, he was instructed by his doctor to control his diet, cooperate with exercise, and receive intensive treatment.
After a month, he stopped using insulin, and slowly should use oral medication. After more than six months of hard work, Mr. Liu later put the weight down. The weight is basically up to standard, slightly on the fat side. By now, Mr. Liu does not even need oral medication, only with diet and exercise can control blood sugar, it can be said that Mr. Liu has done the most ideal way to control sugar.
To summarize, diabetic patients are not on insulin, must be lifelong insulin, do not have a kind of fear of insulin. It is only the most effective and direct means of lowering blood sugar, what other drugs can not handle the blood sugar, look for insulin on the right. When the blood sugar is stable, you can consider stopping or not stopping insulin.
Finally, Nourish wishes you success in controlling your sugar!
I hope the above suggestions can help you, get more information about diabetes, please pay attention to the health care fine-tuning!
Insulin is not addictive, and there is a decision to be made by the condition itself as to whether or not you need to keep taking it.
New-onset type 2 diabetes mellitus with blood glucose that is not very high can be controlled by diet and exercise alone. If blood glucose is high when diabetes is detected, with glycated hemoglobin over 9%, and pancreatic function is protected at the end of intensive treatment with insulin first, there can be a period of time when the diabetes is controlled by diet and exercise alone, supplemented by oral medication if necessary, without the need for insulin all the time.
New onset type 1 diabetes may have a "honeymoon period" where it can be controlled by diet and exercise alone for a short period of time, but after the honeymoon period is over, long-term insulin therapy is required. After the honeymoon period is over, long-term insulin therapy is needed. type 1 diabetes, also called insulin-dependent diabetes, is unable to produce enough insulin on its own, and there is an absolute lack of insulin, so it is necessary to take insulin all the time, except during the honeymoon period.
Gestational sugar many can rely on strict diet and exercise control to bring their blood sugar up to standard. If 1 week of diet and exercise to control blood glucose does not meet the standard, experts recommend starting insulin therapy early, stopping the medication after delivery, and re-diagnosing whether you have diabetes.
However, some of the insulin will be accompanied by lifelong, because the "pancreatic islets" of the sugar users are not responsible for their duties, in order to control blood glucose as healthy people, insulin is needed to help the body work properly. Stopping insulin at will can be dangerous.
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