The prevalence of dyslipidemia in adults in China has been increasing significantly, and many people are detected with dyslipidemia during physical examination. Physical examination is one of the most important ways to detect patients with dyslipidemia, and dyslipidemia, which is characterized by elevated serum total cholesterol (TC), is an important risk factor for atherosclerotic cardiovascular disease (ASCVD). Therefore, adopting a healthy lifestyle and regular checkups can effectively control dyslipidemia and improve the knowledge, treatment and control rates of dyslipidemia in order to reduce and minimize the risk of ASCVD occurrence and death. So what to do with total cholesterol 6.27 mmol/L? Should I take medication?

First of all, total cholesterol (TC) is the sum of cholesterol contained in various lipoproteins in the blood. TC level rises with age, but after the age of 70, it no longer rises but decreases, and is lower in women than in men, and after menopause, women's TC level is higher than that of men of the same age; a long-term diet high in cholesterol and saturated fatty acids can increase TC; genetic factors also affect TC level. Serum total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) levels should be assessed for elevated levels of each, and the presence or absence of cardiovascular disease, hypertension, diabetes mellitus, chronic renal disease complications, as well as the presence or absence of obesity, smoking, and a family history of cardiovascular disease should be evaluated and analyzed for a comprehensive analysis of the above factors. Based on the presence or absence of hypertension, total cholesterol TG and low-density lipoprotein cholesterol LDL-C levels, the residual risk factors for atherosclerotic cardiovascular disease ASCVD included (1) systolic blood pressure ≥160 mmHg or diastolic blood pressure ≥100 mmHg; (2) non-HDL-C ≥5.2 mmol/L; (3) high-density lipoprotein cholesterol HDL-C < 1.0 mmol/L; (4) body mass index BMI ≥28 kg/m2 ; (5) smoking and other factors. Hypertension was the most important risk factor. Those with any of the following are directly classified as high risk for ASCVD: (1) low-density lipoprotein cholesterol LDL-C ≥ 4.9 mmol/L; (2) 1.8 mmol/L ≤ LDL-C < 4.9 mmol/L, and diabetic patients aged 40 years or older. Those with atherosclerotic cardiovascular disease (ASCVD) were at very high risk.

Total cholesterol ≥5.2 mmol/L is considered hyperlipidemia, while total cholesterol between 5.2 and 6.2 mmol/L is considered borderline elevated, and ≥6.2 mmol/L is considered elevated cholesterol. Depending on the patient's individual condition and the risk of ASCVD, the decision of whether or not to initiate pharmacologic lipid-lowering therapy should be made. Patients with TC6.27 mmol/L, such as TG <2.3 mmol/L should be treated with dietary control first; if there is a family history of hyperlipidemia and dietary control is ineffective, lipid-lowering drug therapy should be initiated; if there are diseases such as hypertension, hyperglycemia, etc. should be combined with lipid-lowering drug therapy on the basis of dietary treatment and lifestyle intervention.

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Total cholesterol of 6.27 is indeed a high blood fat problem, but should we take medication? We have to analyze the situation on a case-by-case basis.

In general, clinical diagnosis, the total cholesterol more than 5.2, is high blood fat, and total cholesterol in the range of 5.2 to 6.2, belongs to the borderline elevation, and if the total cholesterol more than 6.2, belongs to the cholesterol elevation, therefore, for the value of 6.27, can be diagnosed as hyperlipidemia, but should belong to the mildly to moderately elevated.

However, when we talk about lipids, we are mainly looking at the risk of cardiovascular disease associated with elevated lipids, so you can't determine whether or not to take medication on the basis of this one value alone. In addition to this value, what is your LDL cholesterol value? In addition to this value, what is your LDL cholesterol value? What is your HDL cholesterol value? Are triglycerides over the limit? Do you have cardiovascular disease? Do you have high blood pressure problems? Have diabetes or chronic kidney disease? Are you obese? Are you a smoker? Is there a family history of cardiovascular disease? These are all factors that need to be considered together.

If there is no cardiovascular disease risk problems mentioned above, then you can consider not taking medication first, through life regulation to intervene in the control of blood lipid indicators, eat less fried, baked goods, control the amount of cooking oil, low-fat diet, strengthen the exercise, every day adhere to the moderate exercise, more fruits and vegetables, adjusting the structure of the staple food, reduce the intake of refined rice and white flour, increase the proportion of coarse grains and cereals, drink more water, drink small amounts of water, quit smoking and limit the alcohol, these aspects can help to improve the level of lipids. Maintain a good work and rest, these aspects can help to improve blood lipid levels, if you can be strict self-discipline, adhere to the above healthy habits, it is recommended to review the blood lipids after 3 to 6 months, in most cases, the blood lipid indicators will have a good improvement.

If in addition to the total cholesterol 6.27, at the same time you have other cardiovascular disease risk, such as the existence of high blood pressure, obesity, and a family history of cardiovascular disease, this situation, a comprehensive assessment, this situation already belongs to the cardiovascular disease of the high-risk patients, the so-called high-risk patients, refers to the cardiovascular disease in the next ten years the incidence of the odds of more than 10% of a determination of the standard, this situation To consider taking drugs to control blood lipids, choose low-dose statins to control total cholesterol will usually have a better effect, but during the drug, pay attention to the monitoring of blood lipids, taking drugs is not the purpose, taking drugs to make blood lipids to reach the standard, to reduce the risk of cardiovascular disease is the ultimate goal, such as cardiovascular disease high-risk of the case, in addition to look at the total cholesterol value after a period of time after taking the drug, the main control of the value of LDL cholesterol at 2%, the value of LDL cholesterol at 2%, the value of LDL cholesterol at 2%. In addition to the total cholesterol value after taking the medication for a period of time, the main control should be the LDL cholesterol value below 2.6, and the non-HDL cholesterol value (total cholesterol minus HDL cholesterol value) below 3.4, in order to be regarded as meeting the standard.

For the risk assessment of cardiovascular disease risk caused by dyslipidemia, there is a complete set of clinical judgment method, the above introduction is just to give you a simple example, the specific situation, generally also consult a cardiologist, to determine whether you need to take medication to control the level of blood lipids, but also to remind you is that, regardless of whether to take medication, life on the strict self-discipline, are essential, a healthy lifestyle! A healthy lifestyle is just as important in reducing the risk of cardiovascular disease!