In the prevention and treatment of cardiovascular and cerebrovascular diseases, aspirin can be called the "red man", is inexpensive and beautiful 'century-old medicine', the status is beyond doubt. It not only has good therapeutic effects, but is even more rare is cheap and easy to get.

As we all know, cerebral infarction, myocardial infarction and other cardiovascular and cerebrovascular accidents, are blood clots in the "blame". Platelets in the blood vessels for various reasons to gather, holding group, will form a thrombus, and then block the blood vessels of this highway. Aspirin can prevent the formation of blood clots.

Aspirin is an antiplatelet aggregation drugs, can prevent platelets in the blood vessels inside the holding group piled up, thus also preventing the formation of blood clots, is a deserved vascular "scavenger".

However, it is not advisable to take two aspirin for nothing to prevent cardiovascular diseases. It is generally not recommended that the general public in order to prevent cardiovascular and cerebrovascular disease, take aspirin on their own, to do the relevant examinations first, by a professional doctor for assessment, need to eat before eating.

Generally stenosis >50% leads to symptoms of organ ischemia and requires medication. Indicators such as blood pressure, blood glucose, blood lipids, platelet count, and blood viscosity are also important in the determination.

To prevent and treat cardiovascular disease, aspirin has to be taken on a long-term, regular basis in order to maintain the concentration of the drug in the blood for a long period of time for it to work.

Since you have been taking aspirin for three years, you should have been cleared by your doctor that it is necessary, and after taking it for so long, you should also have an understanding of the adverse effects of aspirin (e.g., gastrointestinal irritation, gastrointestinal bleeding, etc.).If there is no discomfort, you should continue to takeIf you wish to stop taking your medication, you should go to the hospital for an examination and evaluation. If you wish to stop taking the medication, you should go to the hospital for an examination and evaluation, and then your doctor should help you make a decision. [33]

Xiong Zhaogang, Pharmacist-in-Charge, Xi'an Chest Hospital, Xi'an, China

Aspirin has been taken for more than three years, should have coronary atherosclerosis or other cardiovascular diseases or stents installed, need long-term regular anticoagulation therapy. This question should be to read some of the media about "long-term aspirin is not only useless, but also harmful! However, it is important to note that this is a study of a healthy elderly population, not of patients with cardiovascular disease. For patients at risk for cardiovascular events, there is no doubt about its role in preventing blood clots. Taking a step back, it's a medicine that's poisonous, and healthy older adults don't need to take aspirin for long periods of time!

Aspirin has been around for hundreds of years. In the movie depicting the war era, there are 2 famous drugs, one is penicillin (penicillin) and the other is aspirin. As the research on aspirin continues to deepen, in addition to antipyretic and anti-inflammatory, its use in cardiovascular disease is becoming more and more common because of its antiplatelet effect.

Aspirin is a salicylic acid preparation, and its typical adverse reaction is gastric irritation, leading to stomach upset or gastrointestinal bleeding. In order to minimize the damage of aspirin to the gastric mucosa, aspirin preparations available on the market at this stage are enteric soluble preparations, which do not disintegrate and are absorbed in the stomach, attenuating their adverse effects on the stomach.

In view of the exact role of aspirin in the prevention of thrombosis, if there is coronary heart disease and other patients who need to carry out secondary prevention, it is important not to listen to the claptrap of certain self media articles, so as not to delay treatment, resulting in myocardial infarction and other cardiovascular diseases such as acute attacks, and thus endangering life.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

Have been taking aspirin for three years, and if no adverse reaction occurs, then of course you continue to take it in the future.

I. The "cornerstone" of cardiovascular primary and secondary prevention

I don't know for what reason the subject started taking aspirin three years ago. If it is because of the occurrence of cardiovascular and cerebrovascular related diseases, such as cerebral infarction, cardiac infarction, coronary artery disease, etc., then in order to prevent the recurrence of the disease you need to take aspirin for secondary prevention. If one is over 50 years of age, has diseases such as hypertension, hyperglycemia, hyperlipidemia, etc., and has a risk of cardiovascular morbidity greater than 10% in the next 10 years, one needs to take aspirin for primary prevention. Either way, if aspirin is recommended by your doctor, then aspirin should be taken all the time as long as no adverse reactions occur.

II. Role of aspirin

Thromboxane levels are increased in patients with atherosclerosis, angina pectoris, coronary heart disease, diabetes and hyperlipidemia. This can contribute to platelet aggregation and thrombosis, exacerbating disease progression. In contrast, aspirin passes on acetylating the cyclooxygenase (COX) of platelets, which reduces the production of thromboxane. It can have an irreversible inhibitory effect on thromboxane-induced platelet aggregation.

Now some people are saying that aspirin is toxic and should not be taken for a long time. This understanding is not correct, this is because people do not understand the mechanism of action of aspirin, as well as some people mistakenly believe the rumor. In fact, long-term use of aspirin in patients at high risk for cardiovascular disease can prevent the formation of blood clots, as well as slow down the progression of the disease.

III. Side effects of aspirin

The most common adverse reaction to low-dose aspirin is gastrointestinal mucosal damage, which is because aspirin blocks the biosynthesis of prostaglandins in addition to inhibiting platelet aggregation. The prostaglandins in the body have a protective effect on the gastric mucosa, so aspirin will weaken the barrier effect of the gastric mucosa, thus making the stomach lining susceptible to gastric acid, digestive enzymes and other gastric substances, leading to ulcers and bleeding.

IV. Ways to combat aspirin side effects

1, and proton pump inhibitors (azole drugs) combined: for aspirin-induced damage to the digestive tract, aspirin can be used in combination with proton pump inhibitors. Reduce the secretion of gastric acid, reduce the activity of digestive enzymes, in order to reduce the damage to the digestive tract mucosa.

2, replacement of other antiplatelet drugs: for patients who can not tolerate aspirin and can not stop antiplatelet therapy, can be replaced with Tegretol or clopidogrel for treatment.

V. Aspirin is a "double-edged sword."

"It's a medicine that's poisonous," and every medicine can have adverse reactions unrelated to the purpose for which it is used. A cardiovascular medicine specialist once said that he himself would rather face the risk of stomach bleeding by taking aspirin than having a cardiovascular accident himself. This is because stomach bleeding can be completely cured, whereas cardiovascular disease, once it occurs, remains with you for life.

It is hoped that one day medicine will develop a risk-free drug. But for now, we still have to deal with the "double-edged sword" of aspirin, and it is up to the people themselves to decide what to do.I am Pharmacist Wazi, welcome to follow me and let me be the pharmacist by your side!

Many people in the clinic take aspirin, and when they do, they take it all the time, for years, decades, even decades. It's okay to take it for three years, just keep taking it.

Aspirin, as an antiplatelet agent, is widely used in chronic diseases such as cardiovascular and cerebrovascular diseases. 100 mg of aspirin enteric-coated tablets are now the most used. Patients with underlying medical conditions usually take one tablet daily for the prevention of stroke and other sequelae.

The biggest and most common adverse reaction to aspirin is GI discomfort, such as stomach bleeding. So if there are no adverse effects from taking aspirin, you can continue to take it; if you have severe GI bleeding after taking it, you can adjust it with hydroclopidogrel. There is also a need to stop taking aspirin for a few days before having a surgery, such as a tooth extraction.

"Dr. Meow, Cardiology" Viewpoint:

1. People who have already developed cardiovascular disease or who have a risk of cardiovascular disease greater than 10% within 10 years. All need to take aspirin enteric-coated tablets.

2. Aspirin enteric-coated tablets should be taken for a long time and for life.

3. If there are side effects from taking "aspirin". Stop taking aspirin. Use other antiplatelet drugs.