Entecavir is a first-line antiviral drug for the treatment of chronic hepatitis B. With outstanding efficacy, few adverse effects, and a very low rate of drug resistance, this is a good thing for hepatitis B patients.

The imported drug for Entecavir is called Boludin. It is true that a drug will have many names, generic name and trade name are the two most used, Entecavir is the generic name and Borudin is the trade name. Entecavir is the generic name, and Bolodin is the trade name. Different manufacturers make Entecavir, but there are some differences, some call it a tablet, some call it a dispersible tablet, but it's all Entecavir. So how can you tell the difference between entecavir from different manufacturers? Then you have to rely on the trade name, such as the imported entecavir called Boludin, the domestic Zhengda Tianqing manufacturers of entecavir called Tendin, there is another one called Runzhong, other manufacturers of some of them are called Lei YiDe, some are called BeiShuangDing, and some are called Gambel Light ...... All are entecavir.

Since they are both entecavir, what about the price?

The price is definitely the most expensive of the imported drugs, that is, Boludin is the most expensive. Boludin is about $200/box, and there are 7 tablets in a box, which can be taken for a week, and it will cost $800 for a month (if you pay for it completely out of your own pocket). Why are people's imported drugs expensive? Because Boludin is the original drug, that is, the whole earth's first developed entecavir, people's pharmaceutical companies have invested a lot of money in research and development costs in the early stage, so it is the most expensive to sell, you see the movie "I'm not the God of Medicine" will know, the same drug, the original drug is exceptionally expensive, while the generic drugs are much cheaper.

That's right, the domestic production of entecavir are generic drugs, are waiting for people after the patent period of Boludin, generic Boludin, different manufacturers of generic entecavir, to obtain the trade name is naturally different, called Runzhong, called Tendin, called BeiShuangDing, called LeiYiDe, and so on, the price also makes a difference, specific can be in the online drugstore to check out, dozens of hundreds of a box of all have. Since domestic drugs (generic drugs) do not require much research and development costs, they are sold much cheaper.

With so many domestically produced generic entecavir, the most expensive one would be Tendin from Zhengda Tianqing, why na? Why? Maybe they think their price should be expensive because of their good quality and high investment. In fact, their Tendin is also supported by clearer clinical research data, and the results are similar to the effect of Boludin.

Other manufacturers of entecavir, on the other hand, have not done similar studies and have not published similar high-quality research papers, so there is relatively little evidence and they sell relatively cheaper.

But doesn't it mean that cheap is no good medicine? It doesn't. Many patients can control their disease just as well with the cheapest entecavir. But I am not saying that the domestic ones are as good as the imported ones. There is definitely a difference, but how big is the difference? No one knows, maybe only the manufacturers themselves.

If the economic conditions are average, you can consider using the domestic entecavir for the treatment of hepatitis B. Observe for a few months and review all the indicators, if they are all significantly better, it means that this drug is OK. A drug can circulate to the market, after the supervision of the Drug Administration, I believe it should be no problem.

But who could have known? Even vaccines are in trouble now.

God bless it.

A Hepatitis B patient just returned from Beijing to get his medication, and while talking to me about his review, he said with a big smile on his face that the price of entecavir has been lowered again. This hepatitis B patient gets his medication every six months, so he is not sure when the price of the medication will be reduced.

He started antiviral treatment in 2009, and used Entecavir for the first time, and has been insisting on it until now, and has never changed hospitals or medicines. He is very satisfied with the control of his disease, and there are no side effects from taking this medicine. At the beginning, he did feel very expensive, in the middle of a few times want to stop the drug, but look at the instructions said that there may be risks after stopping the drug is also afraid, the doctor also repeatedly emphasized that you can not just stop the drug, otherwise the condition will be repeated. So he gritted his teeth and persevered.

The same medicine, that is, the packaging has been changed, but the price has been reduced from 26 yuan per capsule in 2009 to 18 yuan now, so he is quite contented now: the economic conditions are much better than before, the price of the medicine has been reduced, and the condition is under satisfactory control. He said he will continue to take it and he will listen to his doctor's advice.

There are many different types of entecavir, and a quick search on the internet will bring up many different kinds, with the same name and different manufacturers, hence the different prices. If the one your doctor chose for you during your initial treatment works well and has no side effects, then it's best to keep using it and not just change it.

Below are photos sent to me by a Hepatitis B patient, one photo is a charge ticket from September 2014 showing Entecavir at $25.60/capsule. The other photo is a charge ticket from June 2018 showing entecavir at $18.50/capsule.

(Entecavir $25.60/capsule in 2014)

(2018 Entecavir $18.50/capsule)

Looking online this would be one of the more expensive ones, I hope the price continues to drop and of course free treatment would be best.

Thank you for your attention!

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Hepatitis B antivirals have now been reduced in price, and the price of entecavir ranges from a high price (imported drug) of about $200 for a box (7 tablets) to a low price of about $50 for a box. The key to choosing which one depends on the patient.

Entecavir is one of the first drugs of all hepatitis B antivirals, the other being tenofovir, because of its effectiveness, fewer side effects, and low resistance rate.

The price of the medicine varies from manufacturer to manufacturer.

The most expensive is the imported entecavir, which costs about $200 a box of seven tablets, and taking one tablet a day would cost about 800 a month.

The cheapest domestic entecavir, with the same dosage and usage, costs about 260 a month.

There are many other medicines in between, all with varying prices.

The active ingredient in all entecavir, whether domestic or imported, is entecavir, and the dose of each tablet is 0.5 mg.

(1) Effectiveness: ①Imported entecavir (trade name Boludin) is the original drug, and its effect, dosage and side effects are very clear. ② Although domestic entecavir is a generic product, most hepatitis B patients in the clinic choose domestic drugs, and the effect is not much different from that of imported drugs. Only a very few patients take domestic drugs ineffective and imported drugs effective. ③ For outpatients, no matter domestic or imported drugs, once the effect is poor, most of them are resistant to entecavir as a component, and it has nothing to do with which manufacturer produces.

(2) Side effects: the side effects of entecavir are relatively few, whether it is a domestic or imported drug, so the use of it is also more assured.

Therefore, the effect of domestic drugs is also clear, and hepatitis B patients can choose according to their financial situation.

Are you taking entecavir now? What do you think of the results? You can leave me a message.

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How much entecavir costs depends on which producer, but also in which province, because drugs are now practicing independent bidding in each province, so the same producer in each province will also cause the price to fluctuate up and down.

Entecavir has many generics in the country in addition to Bristol-Myers Squibb's original drug, Boludin.

Boludin is around RMB 30 per capsule; Zhengda Tianqing's Runzhong is around RMB 85 per box/7 capsules; Fujian Guangshengtang's Enganding is around RMB 70 per box; Sichuan Haisco Fever Ganbe Light is around RMB 55 per box; Shanxi Qingfeng Pharmaceutical's Velicicin is around RMB 100 per box.

So Hepatitis B comrades Mo urgently personally believe that the first push Boludin original drug, followed by now domestic entecavir effect is also good, just too many of the same products.

Entecavir is a guanine nucleoside analog that can inhibit hepatitis B virus (HBV) by competing with deoxyguanine triphosphate nucleoside, the natural substrate of hepatitis B virus (HBV) polymerase. At present, it is mainly used for hepatitis B antiviral treatment, with fast onset of action, strong resistance to hepatitis B virus and low drug resistance. It is mainly used in the clinic for the treatment of chronic adult hepatitis B with active viral replication, persistent elevation of serum alanine aminotransferase (ALT), or histology of the liver showing active lesions. It is the first choice of antiviral treatment for chronic hepatitis B patients.

For the treatment of liver disease drugs are generally relatively expensive. At present, in the market entecavir drugs are Velicin (entecavir dispersible tablets), Boludin (entecavir tablets), Engandin (entecavir capsules) and so on, which are all relatively expensive.

Boludin (entecavir tablets) is a Sino-US joint venture drug, not completely imported drugs, the manufacturer is Sino-US Shanghai Schweppes Pharmaceutical Co. Ltd. and is now widely used in clinical applications. Boludin (entecavir tablets) specifications 0.5mg × 7 tablets, 194.02 yuan a box.

Velicicine (entecavir dispersible tablets) is a domestic drug, the manufacturer is Jiangxi Qingfeng Pharmaceutical Co. Velicicine (entecavir dispersible tablets) specifications 0.5mg x 14 tablets, 146.86 yuan a box.

It is recommended that liver function, viral quantification, hepatitis B five, abdominal ultrasound should be regularly rechecked during the period of medication. Can consult for chronic disease, health insurance patients for chronic disease related procedures, in the outpatient medicine can be reimbursed part of the money spent on their own less.

The market price should be determined by consulting the relevant personnel at the local pharmacy or hospital.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

Entecavir, more such drugs on the market, is the first-line use of antiviral drugs for the treatment of chronic hepatitis B. Like tenofovir, it has outstanding efficacy, and according to the relevant data disclosure, the resistance rate is very low for 6 years of continuous use, which is a good thing for hepatitis B patients. However, the market has called and shape, price also varies, the following is to analyze:

1. Different brands:Entecavir is the generic trade name of the drug, while we are familiar with the Boludin, Tianqing's Runzhong, Lei YiDe, Beyondin and so on is the brand name of each factory to take the brand name, that is, trademarks, and so on.Among them, Borudin is the original drugIt's imported, it's very effective.The others are generic drugs., and the results are great, not much of a difference.

2. Different shapes:Entecavir medication is available in dispersible tablets, capsules, and tablets, of which the dispersible tablets are the best, facilitating attraction and allowing for complete release of the drug, while the others are second best.

3. Effectiveness:According to the relevant disclosure, the efficacy of the drug are quite good, of course, Borudin is the original drug, the effect is also different than the domestic generic, but the difference is not great, followed by the effect of the Tianqing Runzhong is also very good, and the other I understand, it is not as good as the above two categories.

4. Different prices:Dispersible tablets, for example: Boludin a box of 7 boxes, portion 0.5mg per capsule is 210 yuan; Tianqing's Runzhong a box of 7 capsules portion 0.5mg per capsule is 168 yuan; Lei YiDe a box of 14 capsules of 1mg per capsule is 238 yuan, feel that this specification is too pitiful, because the patient taking the dose of 0.5mg per day, and he was 1mg, then need to be flap open and divided into 2 days to eat, is not very convenient. Capsules are not listed.

Overall, depending on your financial strength to choose an original drug over a generic.This drug is now included in the special outpatientIf you don't have a special outpatient clinic, you can take the hospitalized materials: discharge records, proof of illness, drug lists, ID cards, security cards and so on to the township health insurance office or the county health insurance level for, of course, different places need to handle the requirements are different, subject to local conditions.

I used to eat Runzhong Entecavir, 7 pack hospitals to buy a little more than 60, and finally looking for drug dealers to buy 27 pack price from 75 to 110, and now the Hubei Hospital replaced Ruifuen Entecavir 21 tablets only 3.88 yuan, I asked the doctor, the doctor said the ingredients are the same, that is, one is a joint venture one is a domestic company.

The winning price varies from place to place, and so does the selling price. It is expected that the expansion and national talks will involve this variety, after all, there are also many such patients.

Tens and hundreds vary. It's best to go to the hospital for a slow illness. After that the cheapest is more than three dollars a box