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Do Hyperuricemia Patients Need Soda Tablets? I'll talk to you about three areas:

First, what is the role of sodium bicarbonate in the treatment of patients with gout and hyperuricemia?

One of the dangers of hyperuricemia is that it leads to urate crystallization. In the kidneys, as in an acidic environment, which is what we refer to as urine pH 5.0 or so, uric acid stones are more likely to form.

The purpose of taking sodium bicarbonate is to alkalize the urine so that the urine PH is alkaline, which can be less prone to stone formation and uric acid can be easily excreted.

However, it is not true that the more alkaline the urine, the better; too much alkalinity can lead to the development of calcium-related stones.

To emphasize, soda tablets (sodium bicarbonate) are not uric acid-lowering drugs.

Second, not all sodas contain sodium bicarbonate!

There are two types of soda on the market, one containing sodium bicarbonate; the other is carbonated (water and carbon dioxide) soda.

In the end, there are pros and cons to soda tabs!

Not all patients with gout and hyperuricemia are suitable for taking sodium bicarbonate. It contains quite a bit of sodium. Patients with high blood pressure and heart disease should take it with caution.

Regular monitoring of routine urinalysis is recommended for patients taking sodium bicarbonate.

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Now high uric acid is very many people, has become high blood pressure, high blood sugar, high blood fat this "three high" after the fourth high. The harm of elevated uric acid is still very great, we often only know that high uric acid will induce gout, destroy joint function, in fact, there are other hazards. High uric acid can cause kidney stones, and destroy kidney function, causing chronic renal failure; increase the risk of diabetes; promote the progress of atherosclerosis, increase the risk of cardiovascular and cerebrovascular accidents. Therefore, once found that the uric acid is elevated, we should pay enough attention to try to reduce uric acid.

Many people with high uric acid have heard of alkalizing urine and know that you need to take soda tablets to alkalize urine. However, they do not know why taking soda tablets helps to lower uric acid and who is suitable for taking soda tablets.

Uric acid is a product of purine metabolism in the body. Normally, one quarter is excreted in the stool and three quarters in the urine. The portion excreted in the stool is relatively constant, so if uric acid is significantly elevated, you should try to increase the amount excreted in the urine.

Uric acid has a disadvantage in that it has an exceptionally low solubility, and once it exceeds that solubility, it forms crystals that are deposited in the tissues and damage them. This is the reason why elevated uric acid causes damage to the body. Moreover, uric acid is acidic and its solubility decreases in an acidic environment and increases in an alkaline environment. Therefore, in order to increase the amount of uric acid excreted in the urine, it is necessary to increase the solubility of uric acid in the urine, that is, to try to alkalize the urine.

Below a urine pH of 6.0, the solubility of uric acid decreases dramatically and alkalinization of the urine is required.But urine is not as alkaline as it should be.Urine pH > 7.0 will predispose to the formation of calcium oxalate and other types of stones. ThereforeUrine pH is most favorable for uric acid elimination from the urine when it is between 6.2 and 6.9. Therefore, the urine pH should be tested during alkalinization.

Okay, enough about the principle of taking soda tablets to lower uric acid. Let's look at the clinical doctor will do. High uric acid to see a doctor, the doctor will first test urine routine and renal function, to determine the uric acid is significantly elevated, and urine pH value is less than 6.0, will be prescribed soda tablets for lowering uric acid. The method of taking soda tablets is generally 0.5~1 gram Tid, in human terms is to eat 0.5~1 gram at a meal, eat 3 times a day. And ask others to have a routine urine test once every one or two weeks to see the change of urine pH, to make sure that the urine pH should not be more than 7.0, or else it is easy to develop kidney stones.

As you can see here, not all people with high uric acid need to take soda tablets. Only patients with significantly elevated uric acid and a urine pH of less than 6.0 take soda tablets to help lower uric acid. People whose urine pH is between 6.2 and 6.9 do not need to take soda tablets, and it is useless to take them.

Lastly, the role of alkalizing the urine to reduce uric acid by taking soda tablets is limited and only plays a supporting role. If uric acid is significantly elevated or accompanied by clear gout and kidney stones, medication is generally required, such as allopurinol, febuxostat, benzbromarone and so on. At the same time, it is necessary to drink more water, low purine diet, weight loss, moderate exercise and other comprehensive measures.

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Thanks for the invitation to answer, soda tablets are alkaline, can regulate the PH value of urine, reduce the formation of uric acid stone shape, but not all patients with high uric acid can use soda tablets, soda tablets itself is not a uric acid-lowering drugs.

First, let's learn about hyperuricemia. Many foods contain purines, which are metabolized and decomposed by the body to produce uric acid. Under normal circumstances, the kidneys will excrete uric acid out of the body to maintain normal blood uric acid concentration. However, once the body generates too much uric acid or discharges less, hyperuricemia will occur, and in some cases, it will also lead to the occurrence of gout.

High uric acid is, to a large extent, caused by the eating habits of large fish and meat. In recent years, the incidence of hyperuricemia has been rising, the high incidence of people mainly concentrated in obesity, hypertension, high blood pressure, high blood sugar, hyperlipidemia, kidney disease patients, as well as long-term large amount of alcohol, long-term use of diuretics, aspirin and other drugs, patients, but also prone to hyperuricemia.

Doctors suggest that the urine PH of patients with hyperuricemia is best controlled at 6.2-6.8, too low will reduce the solubility of uric acid, which is easy to form urinary stones and damage the kidneys. Taking baking soda tablets can neutralize the PH of urine and reduce the formation of uric acid stones. However, if the urine PH is too high, it will cause calcium stones again. Therefore, patients with high uric acid should review the urine routine regularly and consider whether they need to take baking soda according to the urine PH.

I believe that seeing this, we have already understood. Soda tablets can regulate the PH of urine, but it is not a uric acid-lowering drug, we should correctly take medication.

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Is it useful for people with high uric acid to take soda tablets and what should they pay attention to? This is a very good question that speaks to the minds of many people with elevated uric acid, and Dr. Zhang will talk to you about this issue today, hoping to help more people who are concerned about this topic.

Nowadays, there are a lot of people with high uric acid, and the main reason behind it is the huge change in people's lifestyle, which, to put it bluntly, means that they are eating too much of good food and less physical activity. Of course, there are also some people who have high uric acid because it is also related to their physique, that's another story. However, these patients have a common question, that is, do all people with high uric acid need to take baking soda tablets routinely? This is a question in the minds of many people.

In fact, strictly speaking, not all people with high uric acid need to eat soda tablets, about the matter of eating soda tablets, "China's High Uric Acid Guidelines" is this: it is recommended that when patients with hyperuricemia and gout with a morning urinary pH below 6.0, generally need to simplify the urine treatment, which means that you need to take oral bicarbonate of soda tablets (baking soda tablets) for treatment.

It is important to note that for those patients who are taking drugs to promote uric acid excretion, that is, those patients with high uric acid who are taking benzbromarone, if you monitor the pH value of the urine and find that it is lower than 6.0, then it is especially necessary to take sodium bicarbonate tablets orally to alkalize the urine and try to maintain the pH value between 6.2 and 6.9, so as to reduce the risk of kidney stones caused by acidic urine.

This is Dr. Zhang's answer to the question of whether people with high uric acid need to take oral uric acid-lowering medication, and I hope my answer can help more people with high uric acid. Thank you all for your continued interest.

For more on uric acid, Dr. Zhang recently did a course on how to effectively reduce uric acid, which you can access by clicking on the link below: Dr. Zhang did a course on uric acid that is worth a good read!

Soda tablets, commonly known as sodium bicarbonate tablets, is an alkaline antacid, which can rapidly buffer or neutralize gastric acid after oral intake without directly affecting gastric acid secretion, and can rapidly increase the PH in the stomach to alleviate the symptoms of acid reflux, heartburn, and gastric pain caused by gastric acid hyperacidity, which was commonly used clinically for the treatment of reflux esophagitis, gastritis, gastric and duodenal ulcers, and other acid-related diseases, in the past; however, due to the short-lived effect of the antacid, it could not effectively Relief of symptoms, the production of large amounts of carbon dioxide when neutralizing gastric acid, causing belching and secondary increase in gastric acid secretion, as well as the widespread use of drugs such as proton pump inhibitors (e.g., omeprazole, rabeprazole, etc.) and H2-receptor antagonists (e.g., ranitidine, famotidine, etc.), soda tablets are now rarely used in the treatment of acid-related diseases.

As we all know, high uric acid is easy to form uric acid kidney stones, acidic urine and urate concentration is too high is the main cause of uric acid kidney stones, of which the effect of acidic urine is more important, the more acidic urine (urine pH <6.0), the less uric acid excreted from the urine, taking soda tablets can alkalize the urine, promote the dissolution of uric acid salts and excretion, and minimize the risk of precipitation of uric acid to form kidney stones. It is recommended that patients with morning urine pH <6 can use a simple urine pH meter to monitor morning urine pH regularly, and patients with existing kidney stones need to keep the urine pH at 6.2-6.9 at any time, and the urine pH >7.0 can increase the dissolution of uric acid, but it will also increase the risk of calcium oxalate and phosphate stones, so it is recommended that patients with hyperuricemia and gout have an optimal morning urine pH value of 6.2-6.9. The regular oral dose of soda tablets is 0.5-1g three times daily, and the dose is adjusted according to the urinary pH.

You need to be careful about taking soda tablets regularly:

1. You should not take any medication within 1-2 hours after taking oral soda tablets.
2. The course of treatment should not be too long to avoid metabolic alkalosis and massive sodium retention.
3. Use with caution in patients with hypertension because increased sodium loading may exacerbate hypertension.
4. Appendicitis or those with similar symptoms without a confirmed diagnosis and those with unknown causes of gastrointestinal bleeding are not used as oral medication, as the bloating and abdominal pain caused by soda tablets can interfere with the diagnosis of the disease.
5. Use with caution in oliguria or anuria due to increased sodium load.
6. Use with caution in cases of sodium retention with edema, e.g., cirrhosis, congestive heart failure, renal insufficiency, hypertensive syndrome of pregnancy.
7. Renal function and electrolytes need to be checked before first use.
8. When combined with angiotensin-converting enzyme inhibitor antihypertensive drugs (enalapril, benadryl), potassium-preserving diuretics (spironolactone), and nonsteroidal anti-inflammatory drugs (ibuprofen, aspirin), hyperkalemia is easily induced and should be monitored.
9. Contraindicated in patients with severe acid-base balance disorders, acute and chronic renal failure, chronic urinary tract ureolytic bacterial infections and in patients in whom sodium chloride is absolutely contraindicated.
10. Adverse reactions are mainly flatulence, gastrointestinal discomfort, long-term application needs to be vigilant for elevated blood sodium and hypertension.

We often say that the main ingredient of soda tablets is sodium bicarbonate, which is often used by patients with high uric acid to alkalize the urine, in order to promote the excretion of uric acid, but it is not a drug to reduce blood uric acid, and not all patients are suitable for taking soda tablets;

Under normal circumstances, uric acid will be dissolved in the urine and excreted out of the body, however, the solubility of uric acid in the urine is limited, when too much uric acid is synthesized, the urine will not be able to continue to dissolve uric acid when it reaches saturation, and the excess uric acid will precipitate out of the crystals and form urates, which are deposited in the kidneys leading to kidney damage or urinary tract obstruction;

The more alkaline the urine is, the more uric acid is dissolved, and soda tablets can effectively increase the alkalinity of urine, so that more uric acid is dissolved in the urine, promoting the excretion of uric acid, which in turn prevents the formation of urate crystals; therefore, there is still a benefit for patients with hyperuricemia to take soda tablets, but before considering whether to take the drug, we must pay attention to the following issues:

1, although alkaline urine is conducive to the excretion of uric acid, but, if the alkalinity is too strong, it is easy to form calcium stones, so, before taking soda tablets should be to test the pH of the urine, and then consider their suitability to take soda tablets;

2, increase the amount of drinking water, daily drinking water should be about 2500 ~ 3000 ml, because too little water to drink urine will be insufficient, without enough urine, even if you eat more soda tablets will still precipitate urate crystals;

3, soda tablets contain a large number of sodium ions, take too much, it will increase the burden on the heart, on a variety of cardiovascular diseases is very unfavorable, so before taking medication should consult a doctor to avoid unauthorized use of damage to themselves!

The above is for reference only!

Gout and hyperuricemia patients in the drug prescription, often appear soda tablets (sodium bicarbonate), which makes a lot of people think that since it is a prescription on the appearance of the drug, so soda tablets can also lower uric acid. In fact, we often have a misunderstanding of the prescription, for example, gout and hyperuricemia prescription will also have colchicine, non-steroidal anti-inflammatory drugs, etc., but these drugs are anti-inflammatory and analgesic drugs, can not lower uric acid.

Dr. Liu means that soda tablets (sodium bicarbonate) are useful for people with gout and hyperuricemia, but these drugs do not play a role in lowering uric acid. I'm Dr. Liu Liangyun, a gout doctor at Chengdu Western Gout and Rheumatism Hospital, and today we're going to talk about why friends with high uric acid need to take soda tablets. What should I pay attention to when taking soda tablets?

Why are soda tablets used when lowering uric acid?

As we said earlier, soda tablets cannot lower uric acid, so why do we need to use this drug when treating hyperuricemia and gout? We have to start from the danger of hyperuricemia and gout to the kidneys. We know that one of the common co-morbidities of hyperuricemia and gout is kidney damage. Take a look at a set of data:

About 20% of patients with primary hyperuricemia have clinical symptoms of chronic uric acid nephropathy, and 10% to 20% of patients with gout have clinical nephropathy; the incidence of kidney stones in patients with gout is 200 times higher than that of normal people, and about 25% of patients with gout have urinary stones, of which 80% belong to uric acid kidney stones.

Hyperuricemia is the basis of gouty nephropathy, and uric acid aggravates renal injury by disrupting renal self-regulatory mechanisms leading to hypertension and proteinuria. When blood uric acid exceeds 420 μmol/L, urate precipitates crystals, which are deposited in renal tubular-interstitial sites, leading to chronic interstitial nephritis; and deposited in renal pelvis, renal calyces, and ureter, leading to urate stones.

Studies have shown that for every 60 μmol/L increase in blood uric acid levels, the risk of all-cause mortality from chronic kidney disease increases by about 8%. This is why we use allopurinol or febuxostat, drugs that inhibit uric acid production, and benzbromarone, a drug that promotes uric acid excretion, for uric acid-lowering therapy:Not only can it reduce or avoid acute gouty arthritis attacks and bone destruction caused by urate deposition, but it can also reduce or avoid the onset and progression of gouty nephropathy.

So what is the role that sodium bicarbonate plays in the treatment of hyperuricemia and gout? We need to know that the formation of sodium urate crystals is closely related to the blood uric acid level, body temperature, pH and so on. Physiologically, the pH in human blood and tissue fluids is 7.35~7.45; however, the urinary pH of gout and hyperuricemia patients is generally below 6.0, which is acidic. Numerous clinical data show that the lower the pH of urine, the higher the incidence of renal uric acid stones.

Soda tablets (sodium bicarbonate) also work by alkalizing the urine and adjusting the urinary pH to between 6.2 and 6.9, which promotes the dissolution of uric acid and its excretion from the urine, reduces renal damage caused by uric acid deposition, and lowers the risk of uric acid kidney stones.This is why soda tablets are included in the drug prescriptions for gout and hyperuricemia patients.

Soda tabs don't work all the time and they don't work for everyone.

Since soda tablets can alkalize urine and help uric acid excretion, should they be used all the time in daily life? Actually, this is not the case. Alkalizing urine should be done in moderation, and it is not true that the higher the pH of the urine, the more alkaline the urine is.

What goes around comes around.

When the pH of the urine exceeds 7.0, then although uric acid stones do not occur, they can be over-alkalized, leading to an increased risk of formation of calcium oxalate, calcium phosphate, and calcium carbonate stones; or the formation of a phosphate shell on the surface of uric acid stones, which prevents the dissolution of urate stones.

So when using soda tablets, it is important to be careful that the pH of the urine is neither too high nor too low, but between 6.2 and 6.9, which improves the solubility of urates and avoids the risk of other stone formation.

So the conclusion for soda tabs is:It can increase the solubility of uric acid to some extent to promote the elimination of uric acid, but does not play a major role in lowering uric acid. Moreover, not all patients with hyperuricemia and gout need to use sodium bicarbonate to alkalize the urine.

In general, soda tablets (sodium bicarbonate) are used to alkalize urine in hyperuricemic and gouty patients who have urinary urate stones or are taking medications to promote uric acid excretion and have a urine pH of 6.0 or less.

However, it is also important to be aware of the precautions for taking sodium bicarbonate:

• After taking soda tablets will produce carbon dioxide in the stomach, increasing the intragastric pressure, common belching, bloating, acid reflux and other symptoms, such as gastroparesis, gastric ulcer, gastric pain, gastric hemorrhage and recent surgery, the elderly should be used with caution;
• Long-term use of large quantities of soda tablets can cause alkalemia and electrolyte disorders; use with caution in congestive heart failure, edema, and renal insufficiency;
• Increased sodium load in hypertensive patients taking soda tablets leads to further increase in blood pressure, so use with caution in hypertensive patients and patients with cardiovascular diseases.
• What is easily overlooked by many people is that soda tablets taken with large amounts of milk and dairy products are prone to lactalkali syndrome.

Can I skip the soda tabs and drink soda water instead?

When it comes to soda tablets, some people think of soda water. Some of Dr. Liu's patient friends also often say that they have less frequent acute gout attacks after drinking soda.

Here, Dr. Liu would like to tell you that if drinking soda can cure gout, then there is no need for a doctor to help; in the event that you feel that you have fewer acute gout attacks after drinking soda, it is recommended to check whether your blood uric acid has really come down.

Of course, I'm not denying soda.For people with gout and hyperuricemia, sodas containing sodium bicarbonate are beneficial, but often some sodas contain not sodium bicarbonate but carbon dioxide.

Soda containing sodium bicarbonate, for gout patients, the dual role of sodium bicarbonate and water, can indeed increase the pH of urine, to avoid the concentration of urine, and promote uric acid excretion; drink soda containing sodium bicarbonate, pay attention to do not hold back the urine, more urination, to promote uric acid with the urinary excretion; but also pay attention to the sodium content of this type of soda, drinking too much can lead to increase the burden on the kidneys and elevate blood pressure.

In other words, on a daily basis, if people with gout and hyperuricemia want to drink soda, the first thing to do is to check that their urine pH is below 6.0; secondly, pay attention to whether or not the soda contains sodium bicarbonate; secondly, pay attention to the amount of sodium and sugar in the soda, and lastly, pay attention to the fact that soda is not a substitute for daily water, or a substitute for the soda tablets that are prescribed by your doctor.

If you want to drink soda with sodium bicarbonate, it is generally recommended to drink no more than 800ml per day, usually around 500ml; the rest of the supplemental water to plain water or light tea; in addition, pay attention to timely urination.

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Do soda tablets work for people with hyperuricemia?

Of course it works. Soda tablets, also known as sodium bicarbonate tablets. If you read the directions, sodium bicarbonate tablets are for stomach problems, so why would they be useful for people with hyperuricemia?

How many things do soda tablets do ?

Alkalize urine, most patients with hyperuricemia, urine is acidic, so after taking the soda tablets, can effectively alkalize urate, promote uric acid excretion, thus reducing uric acid.

Soda tablets can also prevent the formation of kidney stones or promote the dissolution of kidney stones. The principle of action is also because the soda tablets can alkalize the urine, so that the ph value of the kidney urine has been maintained in an alkaline environment, kidney stones will not be easy to form, and the already formed kidney stones can also be dissolved.

Of course, you should pay attention to the fact that the effect of soda tablets is also limited, lowering the level of uric acid in about 10-20%. And soda tablets are not suitable for all patients, just said, soda tablets are sodium bicarbonate, after taking soda tablets, the sodium ions inside the body will increase, if Ben is a patient with high blood pressure and heart disease, it may lead to a further increase in blood pressure. So, caution is needed to use soda tablets.

Soda tablets are useful for people with high uric acid.

Soda tablets, also called sodium bicarbonate tablets, are composed of NaHCO3, which is alkaline in solution. Uric acid, on the other hand, is acidic and its solubility decreases in an acidic environment and increases in an alkaline environment. For those who receive uric acid-lowering drug therapy, especially those who promote uric acid excretion drug therapy and patients with uric acid nephrolithiasis, alkalinization of urine can be used to increase the solubility of uric acid in the urine, thus promoting its excretion. Oral sodium bicarbonate tablets are one of the more commonly used methods of alkalinizing the urine, and this method is also used in patients with chronic renal insufficiency combined with hyperuricemia. The general starting dose is 0.5-1.0g, orally, 3 times a day, should be taken on an empty stomach half an hour before meals, this is because the stomach is an acidic environment, if you take sodium bicarbonate after eating, sodium bicarbonate will be easily neutralized by gastric acid, can not be absorbed into the blood as well as the flow of the kidneys to alkalize the urine, and in the stomach to neutralize the gas produced will cause the stomach to bloat and discomfort.

It is important to note that alkalizing urine is not as good as a higher pH. This is because when the pH is greater than 7.0, phosphate in the urine will easily crystallize and precipitate out, forming phosphate stones. The recommended pH for alkalinizing urine is about 6.5, which can be determined by measuring the urine with pH test paper. Of course, sodium bicarbonate should be taken two hours apart from other medications, and sodium bicarbonate should be taken with plenty of water, preferably soft, alkaline water. The use of sodium bicarbonate may cause gastrointestinal discomfort, flatulence, etc. Long-term use should be on the alert for sodium overload as well as hypertension, and prolonged use is generally not recommended.

The above is only a personal opinion, not as a basis for the use of medication, please use the medication under the guidance of a physician, any questions or views are welcome to leave a comment at the bottom of the article.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

Soda tablets have a certain alkalizing effect on urine, can reduce the formation of urate crystals, for the control of hyperuricemia has a certain auxiliary effect. But soda tablets can not inhibit the production of uric acid, also can not play a role in promoting uric acid discharge, so for patients with hyperuricemia, but also need to actively improve lifestyle, if necessary, with the use of uric acid-lowering drugs, in order to stabilize the control of the condition, reduce complications.

Hyperuricemia is defined as an elevated blood uric acid level of more than 420umol/L measured over eight hours of fasting on two occasions not on the same day with our normal diet. For patients with a clear diagnosis of hyperuricemia, they need to start with their daily life and maintain good living and eating habits.

Hyperuricemia patients need to pay attention to daily life: ① do not eat animal offal, shelled seafood and broth; ② eat less animal meat, dried mushrooms, dried beans; ③ eat more fresh vegetables, coarse grains, to encourage the consumption of low-fat or skim milk and its products, you can eat an egg a day; ④ drink more water, more than 2,000 ml per day, preferably in plain water, but also appropriate to drink soda, tea and coffee; ⑤ stop smoking and limit alcohol! If the condition is stable, you can drink red wine; (6) exercise and control weight, but avoid strenuous exercise; (7) work and rest regularly and keep a good attitude; (8) pay attention to warmth and avoid getting cold suddenly.

For some patients with ineffective lifestyle interventions or blood uric acid levels exceeding 540umol/L or with complications such as gout, standardized uric acid-lowering medications can be administered under the guidance of a physician, with attention paid to monitoring the changes in blood uric acid levels and regular reviews, in order to improve the quality of life and reduce the occurrence of gout and other complications.

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