I. The key to the onset of diabetes is dyslipidemia-induced microcirculatory disorders

As a metabolic syndrome, the development of diabetes to its onset is a long process. This process is influenced by many factors, especially from the environment (lifestyle). In pre-diabetes and in the pathologic manifestations of diabetes, it is usually accompanied by dyslipidemia. Similarly, hypertension, which is closely linked to diabetes, is also an important risk factor.

The "high-fat diet" is summarized as an important factor affecting type 2 diabetes. The structural definition of fatty acids, with particular reference to the health risks of trans-fatty acids, is presented, followed by a review of what is known about omega-unsaturated fatty acids. After that, from the introduction of milk, which contains a lot of nutrients (including fatty acids), to the fermented food yogurt, and from there to some basic concepts of "probiotics". It is easy to see that there is a strong link between "high fat and cholesterol levels", overweight, high blood pressure and the risk of diabetes.

II. Core Transformation Achievements of the Second Prize of National Scientific and Technological Progress

National Science and Technology Progress Award, the State Council established the National Science and Technology Award, one of the five awards, scientific and technological progress in the core achievements of the Award "Porcupine" applied to the regulation of diabetes complications, first governance of the gastrointestinal microflora imbalance and displacement problems, regulating the symptoms of glucose metabolism disorders, blocking chronic inflammatory damage, so that the various diabetes complications from the worsening gradually stabilized and reversed. Then, with the adjustment of the order of glucose metabolism and the remodeling of glucose metabolism balance, it will completely unblock the microcirculation obstacles in all parts of the human body, repair the inflammatory damage of microvessels at all levels and the diseased vascular self-tissue cells, and synchronously complete the repair of autonomous replication of the organs and tissue cells damaged by diabetic complications, until the diabetic complications are well regulated.

Science and Technology Progress Award for the core results have been able to effectively regulate hyperglycemia and diabetes complications. 2005, Hunan Tea Group Co., Ltd. Wu Hao Ren Chief Engineer and Hunan Agricultural University Professor Liu Zhonghua led the National Tea Processing Technology Research and Development Sub-center, Hunan Agricultural University, Key Laboratory of Tea Education Department, the National Plant Resource Engineering and Technology Research Center of the scientific research team, together with Tsinghua University, Peking University, Central South University, Xiangya Hospital, Provincial Tea Institute and other domestic and foreign biomedical research at the forefront of scientific research institutes to cooperate, set up a project and began the research journey of the extraction project! After ten years of grinding a sword, finally found the key effective components of Poria tea - Poria tea pigment compounds. And the scientific research project "black tea quality enhancement and efficiency of key technological innovation and industrialization applications" in January 9, 2017 won the second prize of the National Science and Technology Progress Award!

III. "Improvement reactions" and general patterns in the conditioning process

1, conditioning during the various "good reaction" is the body perception to the good change "stress response" expression.Hyperglycemia and diabetic complications in the process of formation and development, will show "three more and one less", vision loss, skin inflammation, dizziness and fatigue and other notable symptoms, and according to the feedback of diabetic complications in all walks of life feedback from the results of the treatment can be seen, the whole process of the treatment, will be personally perceived in the process of rapid relief of the above symptoms and gradually disappeared in the process of different benign "good reaction" experience. and gradually disappear in the process of different benign "improvement reaction" experience. These "improvement reactions" have also verified the remarkable efficacy.

Stress response is a self-adaptive adjustment mechanism of the human body in response to changes in the internal and external environment, experiences and perceptions, etc., in order to ensure the harmonization and efficient operation of all life activities of the body. Therefore, the "improvement response" during the conditioning period is an expression of the "stress response" of the human body to change for the better.

2, the gastrointestinal microflora to achieve balance and return to the earliest "good response".According to the progress of research on components and functions, it can be seen that it enters into the gastrointestinal tract of the human body through the digestive tube of the digestive system, and comes into direct contact with the contents of the gastrointestinal tract and the cells of various tissues, and the first thing it shows is the inhibition of the activity of the harmful bacteria in the gastrointestinal tract and the management of the quantity and scale, so as to realize the balance of the gastrointestinal microflora and the return to the position, and the earliest "better" in the process of conditioning. Reaction". At the same time, with the management of gastrointestinal tract disordered flora, you will experience the "improvement reaction" such as smooth digestion and metabolism, and the gradual disappearance of constipation and diarrhea.

3. With the improvement of blood quality, sugar and various nutrients transportation capacity is enhanced, the body's undamaged cells get a relatively adequate supply of sugar, which is manifested in the first cycle as a significant improvement in vitality.Glucose is the main energy-supplying material for most of the cells in the human body, with the digestion and metabolism of the gastrointestinal tract gradually restored smoothly, the abnormalities of the blood have been effectively regulated, and at this time, the quality of blood in the human body's blood circulatory system is improved, the blood flow is smooth, and the transportation capacity of arteries at all levels of transporting sugar and nutrients is strengthened, and the human body's undamaged cells receive a relatively adequate supply of sugar. At this time, the material and energy supply of the cells will be restored to the state when they are healthy, and the obvious performance is that the energy will be improved, and the feeling of sleepiness will disappear, and the overall vitality of the body will be improved obviously.

4, some people in the second cycle because the human body needs to enhance the active digestion and absorption capacity, reversing the process of transportation also need to consume energy.During the adjustment period of sugar metabolism order, the disordered microflora of the gastrointestinal tract is managed and passive absorption is reduced, especially for those who have damage to the gastrointestinal tract and need to improve the active digestion and absorption ability to ensure the smooth supply of nutrients, and at this time, the body's HDL-C content is increased, and the reversal of the process of transportation needs to consume more energy. Therefore, in the process of adjusting the order of sugar metabolism, some people with poor metabolism, especially in the case of rapid and concentrated drinking, will obviously feel dizziness, panic, fatigue and weakness, such as "good reaction". At this time, we should pay attention to reasonable diet and balanced nutrition, in order to provide sufficient nutrients and energy for cell replication and growth, and repair of inflammatory damage, and we should not avoid eating according to high blood glucose index, so as to effectively improve the "improvement reaction" due to active energy consumption.

5. In the whole process of unblocking microcirculation obstacles, various "good reactions" will occur from time to time.There is no absolute boundary between the several cycles of regulating diabetic complications, which are interactive and continuous. In the process of management, there will be a better appetite, less thirst and dry mouth, less numbness in hands and feet, better headache, palpitation, dizziness, etc., improved immunity and resistance of the body, good improvement of "essence", disappearance of inflammation of the oral cavity, the skin color becomes red and elastic, the heartbeat is stable, the heart pumps blood normally, the liver function is restored and strengthened, the local hidden pain of the kidneys disappears, etc. Various physical changes to the good experience of "good reaction". Recovery and enhancement of liver function, disappearance of localized pain in the kidneys, and other physical changes to the good "good reaction" experience. Especially in the middle and late stages of toning, in the process of unblocking microcirculation obstacles, most people will experience "flashing", "tingling", "pulling pain", "small pimples", "small pain", "small pain", "small pain", "small pain", "small pain", "small pain", "small pain", "small pain" and "small pain". pimples", "redness", "itching", "numbness", "wood" and so on. A series of not violent "will pass when the pain, no pain has passed" of the "good reaction", and the concept of Chinese medicine to express the disease occurs "through the pain is not pain, pain is not pass" just the opposite.

In the process of conditioning, every once in a while, there will be some different drinking experience perception. These drinking experience categories are diverse and unique, the intensity of perception is light or heavy, the duration is different, the fluctuation range of indicators is different, therefore, we need to carefully experience in the drinking process, compared with the previous body feelings, carefully perceived, and when necessary, timely feedback, share, share the experience, and work together to achieve the purpose of diabetes management (strategic intervention) complications!

6. The process of healing from diabetic complications, though difficult, will continue to surprise.Complications of diabetes is the body's microvascular disease, chronic inflammatory cell damage accumulated over the years to evolve the metabolic chronic disease of various tissues and organs difficult, in the process of management, there will be a number of to the good to change the experience of the "good reaction", accompanied by the repeated fluctuations in blood glucose with the amount of dietary high-sugar foods, occasional transient strange feelings in the body, etc. Various "improvement reactions" are experienced. It takes a long time to fully unblock the microcirculation obstacles around the human body, and it is necessary to ensure that the blood quality is good and the blood transportation is smooth. At the same time, inadvertently, will find that foot odor disappeared, purpura, purpura, pigmentation spots and other skin diseases gradually disappeared, ear folds gradually disappeared, colds do not occur or rarely occur, and even chronic gastritis and chronic bronchitis and pharyngitis and other chronic gastritis and pharyngitis and disappeared, atherosclerosis of the carotid arteries disappears, many years of high blood pressure eventually disappeared, the growth of hair black, and so on a variety of unexpected surprises!

Diabetes mellitus is a chronic disease with a long course and many complications, affecting the quality of life and life expectancy, also known as "immortal cancer". Insulin is caused by the relative live absolute lack of pancreatic islet cells, islet cells are not regenerative, so a complete cure in diabetes is impossible, but with the development of science, the treatment of diabetes is also progressing, although not a cure, but scientists have been constantly looking for diabetes drug action of the new target.

Various new drugs mainly include enteroglucagon glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide 1 ( GLP-1).GLP-1 receptor agonists and their analogues: GLP-1 is secreted by intestinal L cells stimulated by feeding, and exerts both intrapancreatic and extrapancreatic functions by binding to GLP-1R. Currently, common clinical GLP-1 analogs include exenatide, liraglutide, and albiglutide, etc.; DPP-4 inhibitors, DPP-4 inhibitors mainly inhibit the degradation of GLP-1 in vivo by DPP-4 enzyme. DPP-4 inhibitors, DPP-4 inhibitors mainly inhibit the degradation of GLP-1 by DPP-4 enzyme in the body. Currently, the DPP-4 inhibitors used in the clinic include: sitagliptin, saxagliptin, vigliptin, alogliptin and riligliptin; Sodium-glucose cotransporter (SGLT) inhibitors, SGLT-2 inhibitors inhibit glucose reabsorption by competitively binding with glucose-binding end of the cotransporter protein to block the action of some of the SGLT-2 cotransporter, which results in the excessive glucose excretion in the urine. The following drugs have been developed and marketed: SGLT-2 At present, the following have been developed and marketed: dagliflozin, cangliflozin, igliflozin, togliflozin, epagliflozin, lugliflozin; there are also some dopamine agonists, G protein-coupled receptor 119, 11β-hydroxysteroid dehydrogenase (11β-HSD1) inhibitor, protein tyrosine phosphatase-1B (PTPv1B) inhibitor, and other new target agents are also in the process of research. Meanwhile gene therapy for diabetes is also on the rise, and it is believed that gene therapy for diabetes will also become possible in the future.

Ref: Kan Weijun et al. New advances in the treatment of type 2 diabetes mellitus [J]. Shanxi Medical Journal, 2018, 47(13).

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

　　Diabetes mellitus is a group of endocrine metabolic diseases characterized by hyperglycemia. It is divided into type 1 and type 2 diabetes, in which type 1 diabetes is related to genetic defects and is caused by insulin synthesis disorders in the body. type 2 diabetes accounts for more than 95% of diabetic patients, and is caused by absolute or relative insulin deficiency and reduced sensitivity of target cells to insulin, and at the same time, it will cause metabolic disorders in the body of carbohydrates, proteins, fats, electrolytes, and water in the patient, etc. Long-term diabetes may also cause chronic damage to target organs, which is often referred to as the complications of diabetes. Long-term diabetes may also cause chronic damage to target organs, which is often referred to as diabetes complications. How to completely cure diabetes is the current endocrine science research hot issues. So is there any latest progress in the treatment of diabetes in recent years?

　　With the development of science, the treatment of diabetes is also progressing, for the time being, diabetes is still the use of hypoglycemic drugs as the main means of treatment, although it can not be completely cured, but scientists have been constantly looking for new targets for diabetes drug action, and continue to discover new therapeutic drugs. The following new drugs have emerged in the last three to five years:

　　The first, Bactrim, is the first drug to achieve a weekly dosing cycle for type 2 diabetes. It has been approved by the State Food and Drug Administration in China.

　　Second, urology, or lysergic insulin, is a "fast-acting" insulin that begins to work 15 minutes after injection, with the effects peaking within an hour and lasting for 2-4 hours.In December 2017, the FDA approved a successor product for marketing.

　　Third, empagliflozin, in 2016, the FDA approved a new treatment regimen for empagliflozin: for reducing the risk of cardiovascular death in adult patients suffering from type 2 diabetes and heart disease.

　　Fourth, Lysine, also known as glycemic insulin, releases insulin slowly and steadily, and for treating adults with type 2 diabetes and people with type 1 diabetes over the age of 6, glycemic insulin is able to maintain blood glucose levels throughout the day. In addition, glycemic insulin, which was approved by the FDA in 2016, has a duration of action of up to 36 hours, which allows people with type 2 diabetes to reduce the frequency of injections and use the medication to control their blood sugar more easily.

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Type 1 diabetes is caused by a genetic defect, due to a defect in insulin synthesis, and requires just regular insulin supplementation.

Type 2 diabetes is an insulin-related disease of life.

Unlike people with type 1 diabetes, people with type 2 diabetes produce insulin; however, the pancreas either doesn't produce enough insulin or the body can't recognize or utilize it (insulin resistance). Glucose in the bloodstream is unable to enter the body's cells and builds up in the bloodstream, causing damage to several parts of the body; on the other hand, cellulardue toInability to get the glucose needed to function properly. Resulting inleading to kidney damage, vision loss.Peripheral nerve deficits, decreased sexual function, heart disease, etc.。

Obesity and lack of physical activity are the two most common causes of type 2 diabetes, which are responsible for about 90 to 95 percent of type 2 diabetes cases... The Centers for Disease Control and Prevention (CDC) reported in 2017 that nearly 100 million people in the U.S. have type 2 diabetes or prodromal diabetes (blood glucose levels are higher than normal but not high enough to be classified as type 2 diabetes when they are prodromal), and that 30 million of them have type 2 diabetes.The prevalence of type 2 diabetes and its complications both underscore the urgent need for new treatment strategies.A 2015 report noted that more than 475 drugs for the treatment of diabetesin the pipeline。

There is no cure for type 2 diabetes, but patients can eat a healthy diet thatExercise regularly to stay active and maintain a normal weightto manage your condition. The latest diabetes advancesProvides patients with a more convenient dosing regimen。

Here are some of the top type 2 diabetes treatment drugs and their latest breakthroughs

Bydureon

Originally approved in 2012, the Patayan BydureonFirst weekly dosing cycle achieved for type 2 diabetes mellitus...Bydureon is a long-acting form of exenatide (an active ingredient in Byetta), but Bydureon needs to be taken twice a day.Bydureon is similar to a GLP-1 agonist in that it binds to the GLP-1 receptor, causing the pancreas to produce more insulin. In October 2017, the FDA also approved Bydureon BCise (exenatide) for once-a-week use for adults with type 2 diabetes using a single-dose auto-injector. Domestic approval was granted by the State Food and Drug Administration (CFDA) in January of this year.

Uloro (insulin lysine)

One of several man-made insulins, Uthera is known as a "fast-acting" insulin that starts working 15 minutes after injection and peaks within an hour and lasts for two to four hours. It is usually taken 15 minutes before or immediately after a meal. Ulorin may also be used to improve glycemic control in people with type 1 diabetes. In December 2017, the FDA approved theSubsequent productsAdmelog（lisproinsulin), Admelog costs less.

Jardiance

People with diabetes are 70% more likely to die from heart disease compared to people without diabetes.Jardiance (empagliflozin), an SGLT2 inhibitor, was initially approved in 2014 to improve glycemic control in people with type 2 diabetes.In 2016, the FDA approved empagliflozin的New treatment option: for reducing the risk of cardiovascular death in adult patients with type 2 diabetes and heart disease.

Ledex (Glycine Insulin)

For the treatment of adults with type 2 diabetes and patients with type 1 diabetes over the age of 6 years, insulin glargine (structure shown above)Ability to maintain blood sugar levels throughout the day. It can be slow and steady when comingliberate (a prisoner)insulin and help control diet and blood sugar levels at night, usually within one to three hours, for 24 hours.

Soliqua 100/33 (glucagon and lisdexamfetamine)

In November 2016, the FDA approved Soliqua 100/33 injection (glucagon and lisdexamfetamine), which is a GLP-1 agonist similar to lisdexamfetamine, and the two drugs are mixed together for injection.

Toujeo (Glycine Insulin)

In March 2015, the FDA approved Toujeo, also known as insulin glargine (the active ingredient in Lysol).Toujeo is a long-acting basal insulin for people with type 1 or type 2 diabetes. Compared to Lysol, Toujeo lasts up to 36 hours, allowing for easier dosing and less frequent injections for people with type 2 diabetes.

Overall diabetes mellitus is a metabolic disease whose etiology and pathogenesis have not been fully elucidated.

Life performance: This is what we all know "three more and one less", that is, eat more, drink more, urinate more (many of my patients because of this long-term nighttime sleep, which leads to other diseases), weight loss (the reason is very simple, mainly because of the human body on the use of glucose obstacles, that can only be consumed by the human body's adipose tissue), tips! Tip, this "three more and one less" is not in everyone, many people have only one or two of the above, which is clinically said to be different manifestations of the same disease.

Diagnosis: the official diagnosis is written in a very complex, difficult to read, first of all, normal blood glucose, generally fasting 3.9-6.0mmol / L, but the reality is that many people in the 3.9mmol / L when there has been a hypoglycemic manifestation, so it can only be said that this is a value in the books (reality is variable ah), the specific diagnostic criteria: with the diabetes mellitus symptoms (that is, more than one of the three less) + arbitrary time Plasma glucose (that is the meaning of drawing venous blood test, not finger blood) "11.1mmol / L, or + fasting blood glucose "7.0mmol / L, or + OGTT test 2hPG (a certain authority of the examination method) "11.1mmol / L. And the above examination should be repeated check again, which is the simplest way I can think of to explain the method.

Diabetes hazards: If the blood glucose long-term peak state, there will be the most serious acute complications such as: ketoacidosis, hyperglycemic hypertonic state (long-term basal blood glucose "20mmol / L, and does not effectively control, it is very easy to appear, such a situation if you do not get to the hospital in time to go to the worst can be fatal, nausea, vomiting, sweating scared to death). Diabetic patients often have boils and carbuncles (i.e., pustules of varying sizes) on both lower extremities or other locations, and such infections can lead to sepsis or sepsis (which is also a more dangerous condition). Li used to have a diabetic ketoacidosis patient in his hands, and his family is from the countryside, and he couldn't control his glucose. He was nauseous, vomiting, and fell unconscious, and couldn't bear the pain before he came to the hospital, and he didn't come to his senses after the night's rescue! The patient's blood sugar is not under control, but the patient's blood sugar is not under control. Chronic complications: 1, is a large vessel lesions (aorta, coronary artery, cerebral artery, renal artery, etc. are violated) so always say, diabetes is one of the biggest scourges of cardiovascular disease disease. Slowly erode your school tube, can be good. 2, microangiopathy, that is, the human body is very small blood vessels (can only be explained in this way to say more than instead of getting complicated la), leading to what results, leading to the emergence of diabetic nephropathy (the process is chronic, but the harm is great ah), retinopathy, a lot of diabetic patients why do you always feel that the eyes more and more difficult to see is the cause of this reason. 33, neurological complications: that is, I said earlier cerebral infarction, cerebral artery, cerebral artery, kidney artery, etc. I said earlier cerebral infarction, cerebral hemorrhage, while accelerating the process of Alzheimer's disease, there is also peripheral neuropathy (that is, limb problems), generally lower limbs than the upper limbs, the first sensory anomalies (the response to a variety of stimuli to become sensitive or slow), after the possible occurrence of muscular weakness, atrophy and even paralysis. 4, this is more common is the diabetic foot, that is, the patient's bilateral lower limb ulcers, infection, serious people have to amputate both lower limbs. Serious people have to amputate both lower limbs (think about it or very scary)

Diabetes treatment: as broadly mentioned earlier, the most basic

1, health education (you have to educate yourself, educate your family, pay attention to rest, live a regular life, stop smoking and alcohol, do not be anxious, etc., etc., etc., you know).

2. Oral drug therapy (generally used for type 2 diabetes, type 1 diabetes on the direct insulin): similar to hypertension diabetes drug commodity name that also counts all of a sudden (especially with some Chinese medicine preparation that is not to talk about it), always have to be divided into the following categories:

①, promote insulin secretion class (in general, diabetes is because of your pancreatic islet function defects, secretion of insulin function is insufficient, so high blood glucose), this kind of drug is similar to the role of the whip, hit the cattle a little bit forward, the pancreas is the cow. This kind of drug is divided into several subclasses first of all is the sulfonylurea class representative drugs: glimepiride, gliclazide (this should be most people have seen the drug, all to gliclazide XX beginning of the general is the drug, but not absolutely), mainly for newly diagnosed type 2 diabetes mellitus non-obese patients and through diet and exercise is not well controlled people. Secondly, the Glinide class represents drugs: Repaglinide is more common, more applicable to type 2 diabetes in the early postprandial hyperglycemic stage or postprandial hyperglycemia mainly in the elderly.

②, biguanide: this is very familiar, is a very good and commonly used glucose-lowering drugs, representative drugs: metformin tablets. It is suitable for type 2 diabetes mellitus that is ineffective in the treatment of simple diet control and physical exercise, especially obese type 2 diabetes mellitus. (2) This product can be used in combination with insulin to reduce the dosage of insulin and prevent the occurrence of hypoglycemia. (3)It can be used in combination with sulfonylurea hypoglycemic drugs with synergistic effect.

③, α-glucosidase inhibitors: this is also very familiar to you, on behalf of the drug acarbose tablets: is a new type of oral hypoglycemic drugs. It has the effect of lowering blood sugar after meals. Generally used alone, or in combination with other oral hypoglycemic drugs, or insulin. His main point is to chew at the same time as the first bite of each meal.

3. is the famous insulin.

ultrashort-acting insulin

The representative drugs are Uloro (lysergic insulin) and Novozymes (menopausal insulin), and so on. The effect of this product starts in 10-20 minutes after injection, the peak effect is in 40 minutes, the effect lasts for 3-5 hours, and it can be injected before meal.

short-acting insulin

There are two kinds of pig and human insulin. The representative drugs, Novolin R, Ulorin R and Gansulin R, are human insulin. The effect starts 30 minutes after injection and lasts for 5-7 hours. It can be used for subcutaneous, intramuscular injection and intravenous drip, and is usually injected subcutaneously 30 minutes before meals.

intermediate-acting insulin

There are Novorin N, Ulorin N, and Gansulin N. The effect of this product starts 3 hours after injection, peaks at 6 to 8 hours, and lasts for 14 to 16 hours. The duration of action is related to the dose injected. Intermediate-acting insulin can be mixed with short-acting insulin or used alone. Intermediate-acting insulin should be injected once or twice daily, depending on the condition. It is given subcutaneously or intramuscularly, but not intravenously. Intermediate-acting insulin is a suspension and should be shaken well before drawing.

long-acting insulin

Such as LaiDeShi (glucagon insulin), this product is generally injected daily in the evening, the onset of action time is 1.5 hours, the effect can be maintained smoothly for about 22 hours, and it is not easy to occur at night hypoglycemia, the adverse effects of weight gain is also less; Domestic long-lasting insulin is zinc fish protein porcine insulin, which has long been used in the clinic. This product starts to take effect 4 hours after injection, 8 to 12 hours for the peak effect, the duration of about 24 hours, the disadvantage is that the drug is poorly absorbed, the effect is not stable. Long-acting insulin is generally not used alone, often combined with short-acting insulin, not for intravenous drip.

premixed insulin

It is an insulin preparation in which short-acting and intermediate-acting insulins are pre-mixed in different ratios (30/70/, 50/50, 70/30), e.g., Novolin 30R is a pre-mixed insulin of 30% Novolin R and 70% Novolin N. The choice of 30/70 or 50/50, 70/30 is based on the patient's post-breakfast and post-lunch blood glucose levels to determine a single dose of subcutaneous injection before breakfast; and on the patient's post-dinner and early-morning blood glucose levels to determine the pre-dinner dose of subcutaneous injection.

Diabetic patients, how to regulate blood sugar to reach the standard, and keep blood sugar stable is the most noteworthy, many friends with diabetes, always thinking of such and such a "therapy" to control blood sugar overnight, but unfortunately such a wish is very good, but in fact basically impossible, for diabetic patients, especially the vast majority of type 2 diabetic patients, must be integrated to regulate the concept of blood sugar, only a comprehensive and comprehensive aspects of blood sugar regulation and control can really put the blood sugar control. Especially the vast majority of patients with type 2 diabetes, must be integrated to regulate the concept of blood glucose, only comprehensive and integrated aspects of blood glucose regulation and control, can really control the blood glucose well.

What are the cures for diabetes? If you are looking for some new and exciting remedies to cure diabetes, then you may be disappointed to read this article, but I am going to introduce some "conventional remedies" that can actually manage your blood sugar.

Treatment of diabetes - dietary therapy

The reason why the problem of type 2 diabetes occurs, in general, or the body on the one hand there is an abnormal metabolism of blood glucose, on the other hand is also thought to be your body there is a problem of excess energy, in order to correct the high blood glucose, it is necessary to first correct the problem of excess energy, and control of the diet, the source of the excess energy control of the basic aspects.

Dietary control of diabetic patients, first of all, to ensure that the body's balanced nutritional requirements, on this basis, minimize the sugar and carbohydrates can be easy to increase the sugar intake of food, as well as try to control the excessive intake of energy, this dietary control must be combined with the actual situation, such as the body is thinner, and at the same time the amount of labor or activity is greater in diabetic patients, it is appropriate to eat more, to ensure that the body's energy For example, people with diabetes who are thin and have a high level of labor or activity can eat more to ensure their body's energy supply and reduce the risk of hypoglycemia due to excessive dieting; while those who are obese and have a low level of daily activity should pay more attention to dieting and controlling their dietary structure, and strengthen their weight control in order to minimize the risk of blood glucose elevation.

Encourage diabetic patients to eat more vegetables, mixed grains rich in dietary fiber, can enhance satiety, but does not lead to increased blood glucose ingredients, at the same time legumes, dairy, meat and other ingredients, but also with the consumption of high-sugar and high-fat food or drink is not recommended to eat more, fine grains should also pay attention to control the intake of small meals, eat small, chewing and slow swallowing, and to control the balance of hunger and energy intake, are all dietary therapies to control good blood glucose Important aspects.

These aspects are easy to say, but in fact, for some accumulated dietary habits for a long time, want to completely change, for many people are very difficult, personal advice: combined with their own situation, conditioning and control of the diet, to achieve their own diet will not be too much suffering because of dietary adjustments, but also beneficial to the control of blood glucose, to achieve such a balance, is reasonable, we can also do the dietary adjustment program.

Therefore, for diabetic patients diet therapy, should be diversified, combined with personal circumstances of a therapy, but the general principle can not be changed, that is, as far as possible through the diet to control the body's excess energy intake, as for this "degree" how to grasp, it is necessary to personal perseverance and the degree of importance of health.

Exercise therapy, a therapy for diabetes

In addition to diet, diabetic patients, as long as the physical conditions allow, life, in addition to controlling the intake, but also to strengthen the consumption and output, and strengthen the exercise exercise, is to strengthen the blood sugar control of another important aspect. Reasonable exercise exercise, not only can enhance the body's energy consumption, but also help to improve the diabetic's insulin resistance, muscle glucose utilization, enhance cardiorespiratory fitness, reduce the risk of cardiovascular disease and other aspects of the benefit, is one of the important therapies for diabetic patients worth adhering to.

The benefits of exercise are clear to many, but being able to do it consistently is difficult for many. People with diabetes have clear benefits from increased exercise in terms of enhancing glycemic control and reducing the risk of diabetes complications. It is usually recommended that people with diabetes should adhere to moderate-intensity aerobic exercise, brisk walking, jogging, swimming, cycling, some swinging ball sports and other sports, can be carried out and adhere to the exercise, pay attention to adhere to, do not interrupt, studies have shown that, if the interval between exercise exercise more than 2 days or more, exercise for blood glucose control to bring the health benefits will disappear, therefore, it is generally recommended that people with diabetes should exercise no fewer than 4 days per week, and the number of exercise days should be no less than 4 days. Therefore, it is generally recommended that diabetic patients should exercise no less than 4 days per week, reasonable choice of exercise, continuous adherence to exercise, in order to enable the body to obtain more health benefits.

The benefits of exercise are not only to strengthen blood glucose control, but also a very important way of life in the control of hypertension and hyperlipidemia, which are frequent complications of many diabetic patients, as well as the prevention of cardiovascular disease, the macrovascular complication of diabetes, regardless of whether it is the case of a high cardiovascular risk or the case of existing For the prevention of cardiovascular disease, the major vascular complication of diabetes mellitus, whether it is a case of high cardiovascular risk or existing cardiovascular disease, as long as the physical condition permits, moderate exercise exercise is an important way of life that is beneficial to cardiovascular health.

Similarly, how to exercise varies from person to person, different conditions, different ages, different blood glucose control, different complications occur, all affect our choice of exercise and exercise intensity, in short, choose the right for you, will not cause the risk of hypoglycemia, will not cause more health risks of the exercise, and long-term adherence to the exercise will be good.

Treatment of diabetes - drug therapy

In addition to diet and exercise, most people with diabetes, also need to be supplemented with medications to strengthen blood sugar control, whether it is taking medications or injecting insulin-based medications, to strengthen blood sugar control and bring it up to standard is an important way to reduce the risk of diabetic complications.

There are many kinds of glucose control drugs for diabetes mellitus, from the way of administration, there are oral drugs and injections, metformin, SGLT-2 inhibitors, DPP-4 inhibitors, insulin agonists, insulin sensitizers, α-glucosidase inhibitors and other drugs belong to the oral glucose-lowering drugs, while GLP-1 agonists, insulin preparations, etc., are injections of glucose-lowering drugs, and not only are the routes of administration different, but also the principles of action are also different, different conditions of diabetes patients can be rationally selected in accordance with their own conditions to apply. The route of administration is different, the principle of action is also different, different conditions of diabetic patients, can be combined with their own situation, a reasonable choice of hypoglycemic drugs to apply.

There are very many types of hypoglycemic drugs available, and various drugs have their own risk of adverse reactions and contraindications, the overall principle of choice is: to be able to effectively control blood glucose (whether postprandial glucose or fasting glucose), there are no contraindications in the body, there are no intolerable adverse reactions to long-term use, and there is a low risk of hypoglycemia during long-term use of the drug, and at the same time, if they also have a cardiac, renal and other aspects of the targeted organ protective effect, such a glucose-lowering drug application and selection, is the best glucose-lowering drug dosing program.

Because each person's situation is different, the specific choice of medication will not say more, but also want to emphasize the point is that you can not just rely on drugs to control blood sugar, so it is impossible to control blood sugar levels, the diet and exercise therapy talked about earlier, combined with the reasonable use of medication, the integrated to regulate blood glucose, in order to be able to better control blood glucose levels, to reduce the dose of medication and the risk of adverse reactions, reduce the risk of hypoglycemia, in short, the In short, comprehensive management and control of blood sugar is the true meaning of good blood sugar management.

There is no cure for diabetes mellitus at present, the direction of treatment is mainly through the correction of the patient's poor lifestyle and metabolic disorders, to improve the patient's quality of life to maintain good control of diabetes mellitus, the main include5 areas: Health education, blood glucose monitoring, dietary therapy, exercise and medication.

I. Health education

This includes the basics of diabetes, how to control diabetes, and the health benefits of well-controlled diabetes. Good health education facilitates the control of diabetes and thus improves the treatment of patients' lives.

II. Self-monitoring of blood glucose

Blood glucose is monitored at least four times a day when type 1 diabetes is undergoing intensive treatment, and eight times when blood glucose is unstable mainly before and after three meals, before going to bed at night and at 3:00 am.

The frequency of self-monitoring of blood glucose in patients with type 2 diabetes can be appropriately reduced. If the blood glucose is relatively stable and is only treated by lifestyle and dietary interventions or oral medications, then the blood glucose should be monitored at least two to three times a week to monitor the fasting or postprandial blood glucose, and if the patient is treated with insulin then it is preferable to monitor the blood glucose at least three to four times a week.

III. Dietary treatment

Dietary treatment is the basis for the treatment of all types of diabetes, and is an essential measure for the prevention and control of diabetes, through which the metabolic disorders of diabetes can be corrected, so that blood glucose and blood lipids can reach or approach normal levels as much as possible.

The general principle of dietary treatment is a diet high in carbohydrates, more coarse grains and less refined rice and flour, low in fat, moderate in protein, and high in dietary fiber.

IV. Sports and exercise

For diabetic patients appropriate exercise exercise can improve the body's sensitivity to insulin, reduce body weight, improve blood sugar and lipid metabolism disorders, but also can reduce the patient's stress.

The intensity and duration of exercise should be based on the patient's general health condition, finding the right amount of exercise for the patient and the program that the patient is interested in. Exercise can take various forms, such as walking, brisk walking, aerobics, dancing, playing tai chi, running, swimming and so on.

The best time to exercise is 1 hour after a meal, counting from the first bite of the meal. The amount of exercise is usually 30 to 40 minutes per session, including preparatory warm-up activities before exercise and relaxation at the end of exercise.

V. Drug therapy

Commonly used drugs for diabetic patients oral drugs are: sulfonylureas, biguanide glucose-lowering drugs, alpha glucosidase inhibitors , insulin sensitizers, glargine-type insulin secretion enhancers and so on.

Insulin preparations are: animal insulin, human insulin and insulin analogs. They are categorized as short-acting, intermediate-acting and long-acting insulins according to their duration of action, and most of them are now mixed preparations.

There are strict indications and contraindications for the use of diabetes medication, and the specific method of use varies according to individual circumstances, please use the correct medication under the guidance of a professional physician.

In conclusion, in addition to the above five therapeutic measures, diabetes treatment should also pay attention to the therapeutic principles of early, long-term, comprehensive treatment and individualized treatment. I hope everyone can get a good prognosis.

What are the therapies for diabetes?

Diabetes mellitus is a group of metabolic disorders characterized by hyperglycemia. Hyperglycemia is caused by defective insulin secretion or impaired its biological action, or both. Prolonged hyperglycemia causes chronic damage and dysfunction of the eyes, kidneys, heart, blood vessels, and nerves.

The treatment of diabetes is not an overnight solution, for diabetic patients, especially the vast majority of type 2 diabetes patients, must be integrated to regulate the concept of blood glucose, only a comprehensive and integrated multifaceted regulation and control of blood glucose, can really control the blood glucose well.

1. Dietary therapy

The diet of diabetic patients should be scientific and reasonable. It should be strictly calculated according to their condition, weight and height, and be scientifically and reasonably organized under the premise of controlling the total calories. The diet of diabetic patients is mainly light, eat more food rich in vitamins and fiber to promote intestinal peristalsis, which is also effective in controlling blood glucose, and avoid overeating, and eat only seven or eight minutes of satiety at each meal.

In addition, you need to strictly control the intake of sugar and avoid eating fructose, honey and drinks containing sugar, which are more easily absorbed and can burden the pancreas. Don't eat fried foods and eat more foods with high fat and cholesterol content.

2. Sports therapy

Exercise can help diabetic patients to balance the metabolic balance of blood glucose and blood lipids, but diabetic patients need to pay attention to the following problems when exercising.

First of all, before exercising, diabetic patients should assess their condition. If blood sugar is too high or too low or blood pressure is too high or too low for strenuous exercise, they can choose some gentle exercises, such as doing calisthenics, playing Tai Chi, taking a walk and so on.

Again, it is important to choose the right time, the amount of exercise to a slight sweat is good, do not overdo it, do not recommend that diabetic patients exercise on an empty stomach, because it may produce hypoglycemia, it is recommended that diabetic patients rest for half an hour after eating, and then get up and do some gentle exercise after proper digestion, which helps to reduce postprandial blood glucose.

Lastly, you need to wear proper footwear when exercising, trim your nails, wear an emergency card with a contact name and phone number on it, and carry a few candy bars with you to avoid accidents.

3. Drug therapy

Medication for diabetes includes oral hypoglycemic drugs and insulin therapy. The specific medication regimen requires consultation with a medical professional. At the same time of drug treatment, it is necessary to cooperate with the improvement of lifestyle, the patient has been seriously practicing a healthy lifestyle for 2 to 3 months, the blood glucose level is still not up to the standard, then use an oral hypoglycemic drugs, and depending on the condition of the need for further combined oral hypoglycemic drugs, or oral hypoglycemic drugs combined with insulin therapy. The most important point is to follow the doctor's prescription for medication.

I am Dr. Huang Zhiyan, dedicated to explaining the complexity of disease knowledge in plain words to help you manage your body. Your praise is my greatest motivation! Also, if you have a family member who suffers from diabetes, please pass this article on to them!

Diabetes is caused by insufficient pancreatic secretion, pancreatic nutrition comes from bile, bile is secreted by the liver, diabetes itself is caused by liver metabolic disorders, as the body's largest detoxification organ, liver metabolic disorders, no one knows the reason, but diabetes needs to regulate the liver, is the basic direction. Do not understand this point, and direct lowering of sugar, obviously is to give up the root of the problem, will inevitably result in lifelong use of drugs.

Keep your mouth shut and your legs open. It's simply not possible to control your blood sugar.