This problem really bothers a lot of gout patients who do not have bad eating habits, once a mother asked me: "Doctor, my child is 16 years old, a student, does not drink alcohol, rarely eat meat, love sports, and there is no bad habits and physical disease, how did the gout ......? "

We should understand that the root cause of gout is currently seen as an abnormal elevation of blood uric acid, normal people's blood uric acid index should not be more than 420 for men and 360 for women, if the blood uric acid height exceeds this standard, it will lead to an attack of gout under the triggering of certain factors. Impact20% of blood uric acid abnormalities are due to diet, while the other 80% are due to problems with the metabolism of blood uric acid, so it does not mean that if you do not eat meat or drink alcohol, you will not get gout!。

If you look at the chart below, you'll see that diet accounts for only 20% of the causes of gout, while the other 80% of the factors that lead to impaired metabolism of blood uric acid are mostly caused by people'sGenetic, weight and kidney problems caused by the。

One paper published in the British Medical Journal in 2018 gives us some food for thought

The study looked at roughly 8,000 healthy men and 8,000 healthy women to see what kinds of foods caused changes in people's uric acid levels and whether there were other factors that affected uric acid metabolism levels.The final conclusion is more subversive: dietary factors that keep people from experiencing elevated blood uric acid levels account for less than 1% of the total, whereas genetics influence people's metabolism of blood uric acid 24% of the time.。

When the cause of hyperuricemia or gout is analyzed in terms of both diet and genetics, it appears that genetics is a much bigger factor, and the authors of this paper go on to say, "Genetically, in the general population, uric acid levels vary almost 100 times more than diet.“

Some of you may not understand this statement very well, my understanding after reading it is, "Genes install a valve in each of us that will lead to abnormal blood uric acid. Some valves are tighter and some are looser, which is also known as individual differences, and whether or not this valve can be turned on may be related to acquired dietary factors, exercise, or other diseases!”

This would rationalize why some people eat a very healthy diet and such a group of people get gout; it would also explain why some people who eat a lot of fish and meat and drink a lot of alcohol every day do not have high uric acid.

While hyperuricemia is the basis for the development of gout, the ability to cause gout varies from person to person, and some of the common factors (the key to unlocking the genetic valve) are as follows:

First, a prolonged high-purine diet.. Whether or not genes have an effect on uric acidIt is an indisputable fact that a long-term high purine diet increases the chances of gout attacks.For example, in coastal areas, the diet structure is dominated by seafood, especially some shellfish, these ingredients tend to be very high purine content ingredients, so in the coastal areas of gout patients are particularly high. And areas that consume more red meat, such as some nomadic areas, the amount of gout patients is also not bad.

Second, drinking alcohol and sugar-sweetened beverages.. Alcohol is one of the most important factors that trigger hyperuricemia, especially beer. Nowadays, beverages are mixed with a lot of fructose, fructose in the body after metabolism will affect the excretion of uric acid, resulting in hyperuricemia is also one of the factors triggering gout attacks.

Third, strenuous exercise.Exercise is known to be good for the body, but strenuous exercise, especially for long periods of time, can affect the body's metabolism of uric acid, especially in the 24 to 48 hours after exercise. This is one of the reasons why gout is more prevalent in the athletic population. There has been a study of badminton players training two hours after the body uric acid changes, in the athletes after 24 hours of exercise, uric acid has a significant increase, and in the day of exercise, uric acid excretion also has a significant reduction. At the same time in the process of strenuous exercise if the water supplementation is not timely, people's bodies will be in a state of mild dehydration, the value of uric acid is equivalent to the concentration of a significant change, but also one of the factors that triggered the gout attack.

Fourth, cold stimulation.. Many gout sufferers have attacks in the middle of the night, when temperatures are generally low. In the course of chatting with some gout patients, it is also found that some patients' first attack is caused by cold, so it is very important for people with hyperuricemia to pay attention to keep warm.

Fifth, trauma.. Trauma is also a trigger for gout attacks.

Sixth, other medical conditions, especially kidney disease, are among the factors that trigger gouty attacks.There are also medications taken by medical patients that can have a significant effect on elevating blood uric acid.

Seventh, the weight factor.Excess weight can lead to metabolic syndrome, which will definitely have an effect on uric acid metabolism and is one of the high risk factors for gout attacks.

summarize

So sometimes gout this disease, just like the wind, noiselessly came, it is recommended that patients with gout and hyperuricemia in the usual life of appropriate control of high uric acid diet, usually drink more water, to do some appropriate jogging or brisk walking such exercise, to help themselves control their body weight, to promote the metabolism of uric acid, to reduce the formation of uric acid, to help themselves better control of the The disease, if the uric acid control is relatively poor, must be under the guidance of the doctor scientific and reasonable medication, do not choose their own according to the gout patient's condition to use drugs.

I am Xie Xinhui, who insists on using simple language to explain the knowledge of complex diseases, it is not easy to code, if you agree with my point of view, please help to point out a concern or click a like it, thank you!

Gout can manifest as sudden or slow onset of joint swelling, pain and localized redness and burning. In fact, gout not only invades the joints, but also often damages the kidneys and other tissues, and in severe cases, it can lead to complications such as disability, gout stones and kidney failure.

The driving force behind gout is hyperuricemia, which is often caused by a disorder of purine metabolism. The body's metabolism produces purines, which are also ingested from food, and the purines are metabolized to produce uric acid.

Why do you get gout even if you don't eat meat or drink alcohol?

Do not eat meat, do not drink alcohol, eat vegetarian every day, why is uric acid still high? This may be a lot of gout patients will send out questions and feelings, excluding the possibility of their own metabolic disorders.

One very common and important thing you may have overlooked in your daily life is the hidden purine killer - chicken essence.

Chicken essence is made from monosodium glutamate (MSG), table salt, powdered chicken meat/chicken bone or its concentrated extract, disodium nucleotide for flavor presentation and other excipients.

1. MSG:The main ingredient in MSG is monosodium glutamate, something that is known to have a bright flavor. Monosodium glutamate is made by reacting glutamic acid with a sodium salt, and glutamic acid can lead to high uric acid. Studies have shown that glutamic acid is converted in the small intestine and liver to glutamine, which increases or promotes uric acid synthesis by providing nitrogen for it.

2. Chicken/chicken bone meal or its concentrated extract:Chicken and chicken bone meal are not low in purines, and its concentrate (thick chicken/bone broth) is not to mention higher in purines than chicken for sure, so this ingredient is also raw uric acid without a doubt.

3. Flavor-presenting disodium nucleotides:Nucleotides, gout friends should not be unfamiliar, purine is the main component of nucleotides, eat nucleotides is equivalent to directly eat purines, uric acid does not rise is strange. In addition to the flavor of disodium nucleotides it is a yeast extract, so many chicken directly contains yeast, yeast purine content is very high, is a gout patient's contraindication to food.

4. spices:Spices are also something that friends with gout should try to avoid, as they can stimulate increased endogenous uric acid production, leading to elevated uric acid.

PS: It turns out that chicken extract turns out to be a killer that smells fresh and tastes good, but is going to form uric acid when you eat it.

Gout is a crystal-associated arthropathy caused by the deposition of monosodium urate crystals, which is directly related to hyperuricemia, and about 5% to 12% of hyperuricemia will eventually develop gout. The body's uric acid is not only affected by exogenous pathways such as diet, but also by endogenous pathways such as the body's metabolism. The exogenous pathway only accounts for about 20% of hyperuricemia, and more hyperuricemia is due to problems with the body's metabolism, which is why gout can occur in some people even if they don't eat meat or drink alcohol. However, good dietary habits are also essential in the prevention and treatment of gout, and under the same conditions people with poor dietary habits are more likely to have acute attacks of gout.

Gout occurs when uric acid rises above the saturation level and crystals precipitate and are deposited in the joints and other tissues. The common triggers of acute gout attack are alcohol consumption, high purine diet, sudden exposure to cold, strenuous exercise, etc. Meanwhile, nearly half of gout patients are obese and overweight people. Therefore, the occurrence of gout is caused by a combination of factors, and its treatment also requires comprehensive intervention.

The key to gout prevention is to control the blood uric acid level, to avoid the precipitation and deposition of urate crystals, at the same time, for patients with gout, the key to its treatment is to promote the dissolution of urate crystals precipitation. Therefore, gout treatment should be clear before the cause of hyperuricemia, cause-specific treatment can often get twice the result with half the effort. Common causes of hyperuricemia are: ① excessive generation: such as purine-rich foods, alcohol, exercise, obesity, hemolysis, lymphoproliferative diseases, psoriasis, true erythrocytosis, rhabdomyolysis, etc.; ② reduced excretion: renal insufficiency, diabetes mellitus, hypertension, hypothyroidism, hyperthyroidism, polycystic kidneys, acidosis, etc.; ③ mixed: glucose -6-phosphatase deficiency, fructose -1-phosphate aldolase deficiency ③ Mixed: glucose-6-phosphatase deficiency, fructose-1-phosphate aldolase deficiency, shock, etc.

Gout treatment includes lifestyle intervention and necessary medication. Lifestyle intervention includes avoiding or reducing the intake of high-purine foods, proper exercise, quitting smoking and limiting alcohol, regular work and rest, maintaining a good state of mind, increasing water intake and weight control. At the same time, under the guidance of the doctor for drug treatment, it is recommended that the acute phase of active anti-inflammatory pain relief, in order to quickly relieve the symptoms; remission attention to lower uric acid treatment, according to the condition of the choice to inhibit the production of uric acid, allopurinol, febuxostat, or to promote the excretion of uric acid phenylbromarone.Thank you for reading, this article by general practice sweeper original writing in today's headlines & Wukong Q&A, reproduced please wish to indicate the source.

As we all know, gout patients have excessive uric acid, where do these acids come from in the body? Where does the acid in the body come from? It must be from what you eat. Although you did not eat meat and did not drink alcohol, but fish, eggs, milk eat it? Must have eaten, otherwise will not get gout, because, all animal food is acidic.

One study had 10 subjects gradually transition from a meaty diet (a general term for animal foods), to a meatless diet, and simultaneously measured the uric acid supersaturation of their urine.

It was found that when dietary meat was drastically reduced, supersaturation of uric acid began to fall dramatically, and continued to fall after entering a meatless diet, eventually dropping to 7% of that of the multi-meat diet.

As you can see, our uric acid levels can change rapidly in a very short period of time based on diet.

There is a view that the body of the purine, 80% from their own metabolism, only 20% from the diet, this point of view is correct or not, do not judge, you can give yourself a test, vegan for a period of time, to see how the results, your body will tell you the answer.

What your body needs, only your body knows best.

To learn more about the health effects of animal foods, see the book The Lifesaving Diet and Dr. Jia Xu's article.

Thanks for the invite.

Gout occurs mainly as a result of abnormal metabolism in our organism, which is why some people develop gout even if they don't eat meat or drink alcohol, while some people who eat meat and drink alcohol don't develop gout.

Of course, although it is said that gout is mainly related to metabolic abnormalities, but diet and other lifestyles also play a very important role in the occurrence of gout, we need to correctly understand, listen to the guidance of professional doctors and standardized treatment.

Gout patients should pay attention to improve the lifestyle, do strictly limit the intake of high-purine foods, do not eat animal offal, shelled seafood and broth, eat less rather than no animal meat, fish; to quit smoking and limit alcohol, preferably do not drink alcohol, in particular, should be avoided to drink beer and yellow wine; to eat more fresh vegetables, drink more water, to white water is preferred; to appropriate exercise, weight control and warmth, to avoid strenuous exercise and sudden cold; to Regular work and rest and maintain a good state of mind, necessary anxiety, depression, stay up late, labor.

We need to pay attention to the medication while improving our lifestyle, and the medication should be individualized, in which we should actively reduce inflammation and pain in the acute stage, and pay attention to lowering uric acid in the remission stage. We also need to monitor changes and regular review while standardizing treatment.

If you have any questions, please feel free to leave a comment at the end of the article to discuss. Follow the author for continuous daily updates on health knowledge.

Is gout related to diet? Of course it's related; but gout is not just a disease of eating; after all, just 20% of uric acid comes from diet, while 80% of uric acid comes from the body's metabolism.

Let's take a look at the risk factors associated with gout and compare them to see if you are a match for one of them:

• Someone in the family has gout, especially a father or mother;
• Favorite high-purine foods such as animal offal, crustacean seafood, thick broths, or hot pots;
• Likes high-fat foods such as fatty meats, barbecues, and fried foods;
• Like to drink carbonated drinks, fruit juices, milk tea, honey and other high fructose drinks;
• Preference for liquor, beer, yellow wine, and other ethanol- or purine-containing liquors;
• Dietary intemperance, overeating, frequent socializing; three meals a day are not regular and quantitative;
• Skip meals from time to time and stay hungry;
• Being overweight or appearing obese;
• Mood swings and impulsiveness;
• Daily stress, often losing sleep or staying up late;
• Busy and often overworked;
• Relationships are not very good, family relationships or work relationships are not harmonious;
• Doesn't like to drink water, sometimes even when thirsty;
• Very fond of physical exercise, especially muscular or athletic exercise, often sweating;
• There are problems with kidney function and occasional abnormalities in urination;
• Elevated blood pressure, blood glucose, or blood lipids have been detected, or hypertension, hyperlipidemia, or diabetes have been diagnosed;
• Long-term use of medications such as antipyretics, diuretics, and asthma medications.

All of these are high-risk factors that can potentially cause a gout attack, and drinking alcohol and eating meat are just one of them. I'm Dr. Liu Liang Yun, a gout doctor, and today I'm going to talk to you about what factors are associated with gout attacks.

Gout attacks can occur with high uric acid

Although hyperuricemia does not necessarily mean that you will develop gout, the essence of gout is hyperuricemia. How high is uric acid high enough to be hyperuricemia? Let's find out.

Uric acid does not exist alone, but is dissolved in the body fluids. About 98% of the uric acid is in the form of sodium salts in the free or non-free state. The saturation level of uric acid is 380 μmol/L in an environment with a pH of pH 7.4 at a normal body temperature of 37°C. The range of normal values of uric acid measured in the laboratory is 150 to 416 μmol/L, or (2.6 to 7.0 mg/dl). The concentration of uric acid in the blood depends on three things, the balance between survival and excretion of uric acid and the volume of the uric acid pool.When the body's blood uric acid concentration is higher than 420 μmol/L, it is hyperuricemia.

Hyperuricemia is not the same as gout, because of individual differences, there are some patients who may not cause gout attacks and other symptoms to occur even though their blood uric acid is abnormally elevated. How many of these cases are there? There areAround 5 to 12% of people with hyperuricemia will eventually develop gout.

And there are certain conditions that need to be in place for gout to strike. It's not the excess uric acid in the blood that makes gout painful, it's the reaction that occurs when urates are deposited in the joints and are recognized by the body.

When the body is continuously saturated with sodium urate, under the stimulation of certain specific conditions, such as exertion, alcoholism, overeating, localized exposure to cold, trauma and other situations, it will lead to the dissolved sodium urate to enter into a state of supersaturation, forming sodium urate crystals, which are deposited in the joints, cartilage, synovium, kidneys and other tissues of the human body, and then later undergoes a series of complex biochemical processes, triggering an inflammatory response.

The pathogenesis of acute gouty arthritis consists of three phases: a phase ofPrecipitation and deposition of sodium urate crystals in tissues inside and outside the joint cavityPhase II isMacrophages located in the joint cavity and differentiated from blood monocytes phagocytose sodium urate crystals and secrete proinflammatory factorsThe three phases areUnder the convergence of the above mentioned pro-inflammatory factors, neutrophils pass through the capillary basement membrane, reach the site of inflammation, phagocytose sodium urate crystals and release a large number of inflammatory factors, leading to gouty attacks。

These people are prone to uric acid tend to be high to develop gout

There are two reasons for high uric acid: decreased uric acid clearance, which reduces excretion, and abnormal uric acid metabolism, which produces too much. Why is uric acid high in some people? Many factors are related to blood urate concentration, including age, gender, weight, body weight, diet, alcohol consumption, work and rest, and mental state. We can look at them one by one.

• Men are more likely to develop gout than women:The sex ratio of the prevalence of hyperuricemia in men and women is at 12.6:1, and changes in the clinical spectrum have revealed an increasing number of female patients. The reason why there are more male gout patients than female is that estrogen level affects the blood uric acid value in females, so that the elevation of uric acid value is not obvious in females after puberty; however, after menopause, the blood uric acid level increases accordingly because of the decrease of estrogen level, which reduces the excretion of uric acid by the kidneys.
• The age of 35 to 50 years is the age of high incidence of gout:Gout is rare in children and pre-menopausal women, but it is mainly found in adult men after the age of 35, which is related to lifestyle and dietary habits, as well as a gradual increase in uric acid levels. The incidence of gout in adolescents after the age of 15 is also increasing, which is related to the high intake of fructose-based foods, while the incidence of gout in young people after the age of 24 is also increasing, which is related to the increased stress associated with this age.
• White-collar people are at high risk for gout:There are differences in blood uric acid levels in different occupations, which are mainly related to the differences in the amount of physical activity in different occupations. Some studies have shown that a relative comparison of the prevalence of hyperuricemia between white-collar workers and permanent residents of the same area reveals a difference in prevalence of 2:1, which is related to the lifestyle of white-collar workers.

• Poor dietary habits influence the development of gout:The incidence of gout is closely related to the standard of living, with the improvement of the standard of living, especially the proportion of animal food in the dietary structure gradually increased, so that the incidence of gout is increasing day by day. This is mainly sea fish, scallops, oysters and other products containing products, brain, liver, kidney, intestines and other animal offal and thick broth, etc.; and the cause of the higher incidence of gout in adolescents and young people is the fructose-containing carbonated beverages, milk tea, fruit juices and other family members of the adenosine acid decomposition and metabolism inhibit uric acid excretion.

• Excessive alcohol abuse affects gout development:Excessive consumption of beer and liquor, in particular, tends to elevate blood uric acid. The main reasons for the effect of ethanol on blood uric acid levels include the fact that alcohol consumption is often accompanied by purine-rich foods, the metabolism of ethanol increases lactate concentration and inhibits uric acid excretion, ethanol promotes the conversion of adenine nucleotides to increase uric acid, and beer produces a large number of purines that are converted to uric acid.
• Three meals a day are not timed and rationed:Three irregular meals a day, hunger and fullness have been associated with gout attacks and can also induce an increase in ketone bodies, which significantly inhibit uric acid secretion and lead to elevated blood uric acid levels.
• Metabolic syndrome leads to elevated uric acid:Gout is often combined or accompanied by hyperlipidemia, hypertension, diabetes, obesity, cardiovascular lesions, renal disease, etc. A study shows that among patients with primary gout, 57.5% are hyperlipidemic, 63.1% have hypertension, overweight and obese people account for 70%, and cardiovascular disease accounts for 11.2%, which is related to the existence of a common soil for these diseases- -insulin resistance.
• Drug Factors:Gout has been associated with the use of certain medications, including diuretics, low-dose aspirin, and cyclosporine use.
• Polygenic genetic influences:Gout and hyperuricemia are polygenic diseases. Among patients with primary gout, 10-25% have a family history of the disease, which is autosomal dominant, but with incomplete epigenetic inheritance. The genetic profile of hyperuricemia is highly variable and polygenic, but multiple factors can influence the expression of gout inheritance, such as age, gender, diet and renal function.

From the analysis of these studies, we can learn that the onset of gout and hyperuricemia is related to dietary factors, as well as to various other associated factors. The etiology of gout mainly consists of uric acid-related genes and inflammation-related genes that make up 60% of the genetic factors, and internal and external environmental factors that make up 40% of the environmental factors, and the combination of these pathogenic factors make up the result of hyperuricemia and gout.

Persistent high uric acid affects gout attacks

After understanding who is at risk for gout attacks, we know that gout attack eating habits are only part of the equation, and that the factors that influence the formation of sodium urate crystals are the key.

What are sodium urate crystals? Sodium urate crystals are aggregates of sodium urate molecules, which can be deposited in all parts of the body except the central nervous system. Their deposition in the joints and their surrounding tissues is the initiating factor of acute gouty attacks, which not only triggers the body's immune response, but also causes direct damage to the local tissues and aggravates local inflammation.

Sodium urate crystal formation is influenced by blood uric acid levels, pH, temperature and local biomolecules, with high uric acid undoubtedly playing a dominant role.

As mentioned earlier, uric acid is saturated in the blood at a level of no more than 420 μmol/L (7.0 mg/dl), and if blood uric acid levels persistently exceed this saturation point over a long period of time, then they are prone to the formation of sodium urate crystals (MSU crystals) in the joints and their surrounding tissues. As you can imagine, the higher the blood uric acid, the greater the likelihood of sodium urate crystals forming and the greater the chance of an acute gout attack.

• 当Blood uric acid <300μmol/LAt that time, the recurrence rate of gout is less than 10%, and the chance of forming gouty stones is almost zero, which is one of the reasons why we set the gouty stone gout blood uric acid attainment value at <300 μmol/L;
• 当Blood uric acid ≥ 360 μmol/LAt that time, the risk of gout was significantly higher, which is why we set the standard for uric acid lowering in gout at <360 μmol/L;
• 当Blood uric acid >420 μmol/LThe recurrence rate of gout was >40% at the time;
• 当Blood uric acid >480 μmol/LThe cumulative incidence of gout was >22% at the time;
• 当Blood uric acid >540 μmol/LAt that time, the recurrence rate of gout is nearly 80%, which is why patients with asymptomatic hyperuricemia need to undergo a combination of pharmacologic uric acid-lowering and nonpharmacologic treatments when they reach this value.

Of course, this one factor alone is not enough to cause gout on its own, but there are other diseases that may cause gout such as uric acid kidney injury, kidney stones, hypertension, hyperlipidemia, diabetes, cardiovascular disease, and so on.

It is now possible to detect urate deposits in the joints of patients with asymptomatic hyperuricemia by means of musculoskeletal ultrasound. It has been shown that "double track" signs are present in 17% of the knees and 25% of the first metatarsophalangeal joints in patients with asymptomatic hyperuricemia; gouty stones are present in up to 36% of patients.

That is, even if there is no gout attack. In order to prevent gout attacks or complications caused by the deposition of urate crystals in various organs of the body, it is important to pay attention to the presence of hyperuricemia and prevent it before it occurs.

These habits can easily trigger a gout attack

When is gout likely to strike? Although gout often strikes suddenly, there are bands of time when the attack-prone conditions overlap. The time of day when acute gouty arthritis is likely to strike is between late at night and early in the morning. The reason for this is that when a person is asleep, the parasympathetic nervous system is dominant, blood pressure drops, blood flow slows, and body temperature drops.

Hyperuricemia does not necessarily gout, but the appearance of easy to induce gout can still be found. Once we find hyperuricemia, then we have to avoid the appearance of these triggers, the following picture tells us what are the scenarios that can easily induce gout, specifically for you to do a brief analysis:

• Movement:In particular, injuries occurring in sports, regardless of the severity and size of the injury, can make gout attacks. Mainly include long time walking, sprains, inappropriate shoes, etc. can lead to gout attack; and exercise without attention to rest, intense exercise without attention to hydration, etc., resulting in urine concentration, uric acid can not be excreted normally, joints are easily affected, these are prone to urate level suddenly increased, thus triggering urate crystal deposition and gout attack.

• Diet:High purine diet has always been regarded as an important cause of gout attacks, especially animal purine-rich animal offal and seafood, easy to lead to a sudden increase in the body's uric acid production, thus triggering gout attacks; fructose-rich diets consumed in large quantities on the one hand to inhibit uric acid excretion, on the other hand to promote the production of uric acid, can also lead to a sudden rise in the concentration of uric acid in the blood; in addition, dietary inordinateness, binge eating, hunger and so on can also be In addition, poor diet, overeating, and hunger can also trigger gouty attacks.
• Drinking:Alcohol abuse is an independent risk factor for acute attacks of gout, and the effects of alcohol abuse on gout are much more severe than diet. This is because alcohol abuse itself causes the body to increase blood lactate concentration, inhibits uric acid secretion from the renal tubules and decreases uric acid excretion; promotes adenine nucleotide conversion, allowing for increased uric acid synthesis; and alcohol abuse causes the body to become dehydrated, resulting in rapid fluctuations in uric acid levels.

• Drugs:Many drugs can cause acute gouty attacks, diuretics such as furosemide and hydrochlorothiazide, as well as antihypertensive drugs containing diuretics can lead to acute gouty attacks. Especially in menopausal women, the application of diuretic drugs due to cardiovascular disease and renal pathology leads to polyarthritis gout, with milder symptoms, but the appearance of nodules faster, often misdiagnosed as osteoarthritis. Clinical use of uric acid excretion drugs and inhibit uric acid synthesis drugs to lower uric acid treatment, may also be due to a sudden decrease in blood uric acid lead to the emergence of "crystalline pain", so the need to prevent the use of drugs.

• Drinking water:Including the previously mentioned sports and other reasons lead to a lot of sweating, long time sweating, usually do not have the habit of drinking water or even thirsty are not drinking water, it is easy to lead to the concentration of urine, uric acid can not be normally excreted through the urine, so that a short period of time the blood uric acid increases leading to acute attacks of gout.
• Other:Lifestyle behaviors such as overexertion, exposure to cold, stress, and late nights can lead to gout attacks. Poor perfusion of tissues at the ends of the limbs can lead to a drop in skin temperature, which reduces the solubility of local urates and can promote the formation and deposition of crystals; poor lifestyle behaviors can lead to metabolic derangements in the body and low immunity, which can make uric acid production and excretion problematic.

All in all, dietary habits are one of the factors, but there are other factors as well, from the appearance of hyperuricemia with increased uric acid, to the triggers that lead to gout after the hyperuricemia persists. This is why gout is a seemingly simple but actually complex joint disease. Clinical diagnosis and treatment, often also need to clarify the etiology, pathology and triggers of the relevant onset of the disease, in order to treat the symptoms; for patients with only hyperuricemia, but also please remember these twelve words:Drink plenty of water, keep your mouth shut, and lose weight.

It is not that eating meat and drinking wine will get gout, but to limit meat and wine after getting gout, for normal people, normal drinking and eating meat, within the body's normal metabolism, there will be no high uric acid problem at all, because the kidneys can completely give you to discharge. Unless you are like the ancients every day, two pounds of beef, ten pounds of white wine, more than the body's normal metabolism, will cause high uric acid triggered gout.

Causes of Gout

1. Problems with the kidneys. Human metabolism produces 2/3 of the uric acid need to be excreted through the kidneys. If the kidney function is not good, nephritis, uremia, a lot of hardening and destruction of renal units, residual renal units, can not meet the needs of this work, will lead to the accumulation of uric acid in the body, resulting in high uric acid and then cause gout.

2. Eating too much high purine food. Every organ in the human body has a maximum working limit, just like the rated power of the machine. If the human body can metabolize up to 500 grams of meat, but you have to eat into the 1000 grams of meat, uric acid is not high to be strange.

The dangers of gout

A more serious problem is gout stones. When the body's uric acid is too high, it will form uric acid crystals deposited into the joints. But the stones, like the hard texture, can cause joint deformity bone deformation, the original normal physiological function is destroyed, not only very painful. The most important thing it can make you lose the ability to move, imagine, the joints can not bend to move, the quality of human life caused a great impact.

Prevention of Gout

To prevent gout, you need to lower uric acid. There are two main areas, intake and excretion. The main way of prevention in general is to reduce the intake of high purine food. Because this is the easiest thing to do, if it is because of excretion problems, kidney problems or its own metabolic abnormalities, these problems may not be very easy to treat. If you increase excretion through medication, you will also increase some of the side effects of the medication. And directly from the source to reduce is often the most simple practical and effective way. Eat as little as possible of seafood, alcohol, tobacco, beverages, meat, animal offal, and other foods that are high in purine content. Eat more fresh fruits and vegetables and drink more water.

I am a medical doctor, a resident, specializing in the popularization of medical knowledge for the benefit of human health, if you want to know more, please pay attention to me, have questions can be left a message, will respond!

Some people get gout even if they don't eat meat or drink alcohol, why is that?

You may find a phenomenon, some people every day fish and meat, drinking blood uric acid is not high, while some people do not rarely eat meat and drink but got gout, this is how it is? Estimated that not many people know it, today I will analyze the possible reasons.

1. Problems with the kidneys:

Under normal circumstances, about 2/3 of the uric acid in our body is excreted through the kidneys, and the remaining 1/3 is excreted through the gastrointestinal tract, biliary tract and other channels, from which we can see the importance of the kidneys; 80% of the blood uric acid in our body is produced by ourselves, and 20% is produced through the intake of food, if the gout patient's kidneys have a problem, even if he doesn't eat meat, don't drink alcohol, the body can't excrete the uric acid produced in time. If a gout patient has kidney problems, even if he doesn't eat meat or drink alcohol, the uric acid produced in his body can't be discharged in time and it will easily trigger gout;

2. Inborn abnormalities of enzymes involved in uric acid metabolism:

Some people get gout because they are born with some enzyme defects that prevent uric acid from being metabolized in the body, thus raising blood uric acid and triggering gout;

3. It's not just meat and alcohol that contain more uric acid:

Some people ask me, "Doctor, I don't eat meat and drink alcohol anymore, why is my blood uric acid still so high? I asked him about his recent diet and he said he likes to eat soybeans, mushrooms and other foods, and he eats a lot of them. After I heard that, I think there is a reason why he can't control his blood uric acid; high-purine foods don't only include meat and alcohol, but also mushrooms and soybeans are high-purine foods, and eating too much of them can trigger gout;

4. Some are due to strenuous exercise:

When a person performs strenuous exercise the body will produce a large amount of lactic acid, and the presence of lactic acid will competitively inhibit the excretion of uric acid, so even if you don't eat meat and don't drink alcohol, the uric acid level in the body will rise, thus inducing gout.

Final Summary: Even if you don't drink alcohol or eat meat, gout attacks can be caused by eating high purine foods like mushrooms and soybeans, congenital defects of enzymes in the body, decreased kidney function, and strenuous exercise.

The above is my answer to the question, purely hand-typed, it is not easy, if you feel that the writing can be rewarded with a praise, if you have any questions you can leave a message below ......

Some people get gout even if they don't eat meat or drink alcohol, why is that?

Yeah, why?

Western medicine says it's the purines, uric acid, the cause, the treatment is to lower uric acid, indeed, ah, when the uric acid down, it is indeed not painful. When the uric acid down, gout this disease is well? No, when encountered triggers will again attack. From then on, it's just the same thing over and over again, and the more serious it gets.

Normal values for uric acid are male: 149-416umol/L. Female: 89-357umol/L.

Through the above data we can see that we normal people will have uric acid in the body as well, when the value of uric acid exceeds the normal value may cause gout.

Normal people have uric acid in the body as well, it will be eliminated from the body with excretion, uric acid is not stored in the body, the uric acid value will not increase, then the possibility of triggering gout is less.

From this we can see thatLowering uric acid is not the best way to treat gout, the best treatment should be to not allow uric acid to remain in the body。

Uric acid is stored in the body due to decreased kidney function, which causes gout.Uric acid is excreted through urine, the production of urine is done in the kidneys, if the function of the kidneys is normal, the excessive uric acid will be eliminated from the body, and now the increase of uric acid in the body indicates that the elimination function of the kidneys has decreased.

Therefore, by restoring the function of the kidneys, the kidneys will be able to work properly, so that uric acid will not be retained in the body, and naturally gout will be cured.

So what makes the kidneys function less well?

We can't live without electricity nowadays, if there is a power outage or low voltage, think about it, can all the electrical appliances still work properly? Can a cell phone work without power? Can computers work without power? If the voltage is low, can the air conditioner and refrigerator still work properly?

If we look at the five organs and six bowels of the human body as a variety of electrical appliances it is easy to understand.

Isn't it because the kidneys are not electrified enough to cause gout by decreasing the function of the kidneys and making uric acid storage?

Get this kidney electrical problem fixed and gout is restored.

We think about ah is not this reason, no matter what people, no matter how robust, if a month, two months do not eat and drink, will starve to death? Starve to death is sure, this sentence shows that people live is to rely on the spleen and stomach to dietary substances, converted into the body's energy needs, so this energy we can not be understood as is electricity? Electricity is well understood, in fact, is electricity, then the spleen and stomach is not the power plant ah.

Spleen and stomach is a power plant, send enough electricity, in order to supply the whole body organs, each organ has enough electricity in order to work properly, on the contrary, if the electricity is not enough, so it will cause the five viscera and six bowels of the electricity is not enough, the heart's electricity is not enough, so there is a heart failure, renal failure, lung failure and so on diseases. The spleen and stomach send insufficient electricity, so that the kidneys have enough electricity, so that the voltage of the kidneys is too low, so the function of the kidneys decline, so that the excretion of uric acid declines, so that the uric acid is too much to cause gout.

What causes the spleen and stomach, the power plant, not to generate enough electricity?

Of course, it is the spleen and stomach, the power plant itself, that also has insufficient electricity. The spleen and stomach themselves are unable to emit sufficient electricity because of insufficient electricity, and therefore the function of the spleen and stomach has declined.

And what causes the lack of power in the spleen and stomach?

The electricity we mentioned above is called yang qi in Chinese medicine, and yang qi is heat, the opposite of heat is cold, and cold can consume heat.

The answer is the ubiquitous cold, which consists of two main categories, external and internal.

Outside the cold into the human body to go through the fur, skin, meridians, six internal organs, five organs of the process. Now many people, to the winter screw can be frozen also want to body strip, the human body's Yang Qi to a large number of release to resist the cold gas, long time the human body's Yang Qi deficiency. Summer air-conditioned house is more cold into the human body, because the pores of the human body in summer is open.

Internal cold refers to the diet, now there is a refrigerator, cold food can be eaten anytime, anywhere, ice cold beer, drinks, milk tea, are cold products, fresh milk, seafood to eat more hot its nature is also cold.

We hold a piece of ice in our hands, after a while, this piece of ice is turned into water, it is the body temperature that turns this piece of ice into water, then what about the cold foods we eat? These cold foods will certainly consume the body heat, time will cause the spleen and stomach yang qi deficiency, spleen and stomach yang qi insufficiency, function decline, spleen and stomach function decline can cause the following two situations.

A decline in the function of the spleen and stomach, its function of transportation and digestion, so the function of chemically generated qi and blood decreased, thus causing a lack of power in other organs.

Secondly, the function of the spleen and stomach declines, and its function of transportation and digestion declines, so water and dampness are stored in the body, and water and dampness spread all over the body, hindering the operation of qi and blood in the body.

External cold and internal cold damage the yang qi in the body. Spleen yang is damaged, its function declines, and it does not produce enough energy, causing the function of the kidneys to decline. The decline in the function of the kidneys causes uric acid to be stored in the body, and finally causes gout.

Therefore, the cause of gout is not whether you eat meat or not, drink or not drink, it depends on whether you are cold or not, cold is the main culprit causing gout.

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The formation of uric acid buildup is caused by two things: too much intake of purine substances, the

The second is the body's poor excretion of uric acid. This has resulted in certain patients who don't usually drink alcohol and don't overeat developing gout even with excretion problems.

The body's poor ability to excrete uric acid is often congenital.

There is a clear genetic predisposition to the disease gout.

However, the previous generations of patients may not always have had the disease due to poor dietary conditions of the previous generations. So people should not think that they can rest easy just because their fathers or grandfathers did not have a history of gout.