This is a very good question to ask! Even though both painkillers and ibuprofen can be used for analgesia for mild to moderate pain, there is quite a difference between the two of them.

First.analgesicIt is a compound preparation, and each pain relief tablet containsaminopyrine (loanword)150 mg.finasteride150 mg.caffeine (loanword)50 mg.phenobarbital15 mg.

ibuprofenIt is a single-prescription preparation, the composition of which contains per tabletibuprofen100 mg.

Secondly.Ibuprofen belongs to the nonsteroidal class of antipyretic and analgesic anti-inflammatory drugs.

And the painkillers in theaminopyrine (loanword)It belongs to the pyrazolone class of antipyretic and analgesic anti-inflammatory drugs;finasterideIt belongs to the acetanilide group of antipyretic and analgesic anti-inflammatory drugs.

caffeine (loanword)It is a central nervous system stimulant that excites the brain, increases sensitivity, and constricts cerebral vascular effects. The purpose of adding caffeine to painkiller tablets is to enhance the effect of aminopyralid and finasteride in relieving headaches.

in painkillersphenobarbitalMainly sedative, hypnotic, anticonvulsant effect.

So what is the difference between the uses of the 2 medications, Dexedrine and Ibuprofen? Which one of them has more side effects? Today I'm going to join you guys and gals and talk about this question, just for reference.

Painkillers and ibuprofen have different focuses of use

According to the drug inserts for Dexedrine and Ibuprofen, the indications for the two differ in focus.

1. The indications for pain relief tablets focus on.(common) coldIt causes mild to moderate pain such as fever, headache, arthralgia, and neuralgia;

It can also be used for general migraines, menstrual cramps and other mild to moderate pain.

2. Indications for ibuprofen focus on.For rheumatoid arthritis, osteoarthritis, acute gout, tendonitis, etc.inflammationsCauses mild to moderate pain.

Of course, it can also be used for toothaches, muscle aches andMigraine, dysmenorrhea and other mild to moderate pain; and for fever caused by colds, headache, arthralgia, neuralgia and other mild to moderate pain.

Side effects differ between painkillers and ibuprofen

Depakote is a prescription drug and ibuprofen is an over-the-counter drug, and just from that alone you can see that the side effects of Depakote should be greater than the side effects of ibuprofen.

The difference in the magnitude of side effects between Dexedrine and Ibuprofen is mainly due to the different ingredients in both of them.

Among the side effects of painkillersMainly from aminopyralid and finasteride, as it is both higher, at 150 mg/tablet each; while caffeine and phenobarbital are lower, at 50 mg and 15 mg, respectively.

Side effects of aminopyralid can include vomiting, rash, fever, profuse sweating and the occurrence of stomatitis.

Side effects of finasteride can include renal papillary necrosis, interstitial nephritis with acute renal failure.

Therefore, when taking painkillers, do not arbitrarily increase the dosage and also do not take them for a long period of time, as caffeine and phenobarbital have certain dependence and addictive properties.

And the side effects of ibuprofenOnly a few patients may experience nausea, vomiting, heartburn, or mild dyspepsia in a few patients.

To summarize:Dexedrine and Ibuprofen are 2 completely different classes of analgesic medications used for mild to moderate pain;

One of the depo tablets is a combination; while ibuprofen is a single preparation;

Depakote is mainly used to relieve mild to moderate pain caused by colds; while ibuprofen is mainly used to relieve mild to moderate pain caused by inflammation.

Depakote is a prescription drug and ibuprofen is an over-the-counter drug.

The main side effects of painkillers come from aminopyralid and finasteride, plus caffeine and phenobarbital have some dependence and addictive properties.

All in all, the side effects of Depo-Provera are > the side effects of Ibuprofen.

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Dexedrine and ibuprofen are both non-steroidal anti-inflammatory drugs (NSAIDs), which are non-opioid analgesics (an opioid analgesic is a medication that is used clinically for the treatment of severe pain, such as morphine, an analgesic that is strictly regulated by the state).

Non-steroidal anti-inflammatory drugs (non-opioid analgesics) side effects

GI side effects:All non-opioid analgesics can irritate the gastric mucosa and cause GI discomfort (e.g., heartburn, dyspepsia, nausea, bloating, diarrhea, and stomach pain), peptic ulcers, and peptic hemorrhage (gastrointestinal bleeding).

Bleeding:All non-opioid analgesics have the effect of preventing the aggregation of platelets (cell-like particles in the blood that help to stop bleeding in case of blood vessel injury). Therefore, non-opioid analgesics can increase the risk of bleeding, especially if the gastric mucosa is irritated by non-opioid analgesics, which can cause GI bleeding.

Side effects associated with fluid retention:Fluid retention and swelling can occur in 1% to 2% of patients taking non-opioid analgesics. Regular use of non-opioid analgesics also increases the risk of kidney disease, sometimes leading to kidney failure (called analgesic nephropathy).

Increased risk of heart and vascular disease:Recent studies have shown that all non-opioid analgesics except aspirin increase the risk of heart attack, stroke, and blood clots in the lower extremities, and that this risk increases with higher doses and longer durations of use.

Both aminopyralid and finasteride contained in Dexedrine Tablets have more pronounced adverse effects compared to ibuprofen. Vomiting, rash, fever, profuse sweating and stomatitis may occur with aminopyralid. Prolonged use of finasteride can cause renal papillary necrosis, interstitial nephritis and acute renal failure, and can also cause dependence on the drug. Finasteride also tends to make hemoglobin form methemoglobin, which reduces the oxygen-carrying capacity of the blood and leads to cyanosis, and can also cause hemolysis, liver damage, and has a certain degree of toxicity to the retina.

It is important to note that both drugs should be used "symptomatically", not more than 5 days for pain relief and not more than 3 days for antipyretic, and if symptoms are not relieved, consult a physician or pharmacist immediately.

Ibuprofen belongs to arylpropionic acid non-steroidal anti-inflammatory drugs, mainly through the inhibition of cyclooxygenase and reduce the synthesis of prostaglandins, thereby reducing the prostaglandin-induced tissue congestion, swelling, and reduce the sensitivity of peripheral nerve nociception, and to play the anti-inflammatory and analgesic effects, and through the hypothalamus thermoregulatory center and play a role in antipyretic. It is used to relieve the symptoms of acute attack or persistent joint swelling and pain of rheumatoid arthritis, rheumatoid arthritis, osteoarthritis, gouty arthritis, spondyloarthropathies and other chronic arthritis; it is used to relieve the pain after surgery, trauma, strain injury, menstrual cramps, lower back pain, dental pain, headache, and other acute mild and moderate pain. For the relief of tendon and tenosynovitis, bursitis, shoulder pain, myalgia, myalgia, muscle movement after injury pain and other non-articular a variety of soft tissue rheumatic inflammation and pain; can also be used for colds, acute upper respiratory tract infection, acute pharyngitis and other diseases caused by fever.

The most common side effects of ibuprofen are gastrointestinal reactions, such as dyspepsia (about 16%), nausea, vomiting, heartburn, and gastroparesis, which are mild and disappear after discontinuation of the drug, and can be tolerated without stopping the drug. Occasionally, peptic ulcer and gastrointestinal bleeding (incidence ≤1%) are seen, and perforation due to ulcer has also been reported. Hepatotoxicity is mild, liver function abnormalities can be seen, mainly manifested as elevated transaminases.

Drowsiness, dizziness, headache, and tinnitus are occasionally seen with ibuprofen with an incidence of 1-3%. Depression or other psychiatric symptoms, blurred vision and toxic amblyopia are rare. Lower extremity edema has been seen in a few patients with the drug. Acute renal insufficiency with renal papillary necrosis may occur in some susceptible individuals with underlying nephropathy. Blood urea nitrogen and blood creatinine levels are elevated and creatinine clearance is decreased. Bronchial asthma attacks may occur in susceptible individuals.

High doses of ibuprofen may prolong bleeding time by inhibiting platelet aggregation (this effect may disappear after 24 hours of discontinuation), as well as leukopenia, granulocytopenia and even granulocyte deficiency, platelet deficiency, and pancytopenia. Individual patients may become anemic due to gastrointestinal occult blood. Allergic skin reactions are uncommon and tend to be transient urticarial, purpuric or erythematous changes, often accompanied by pruritus.

Degreaser belongs to the compound antipyretic and analgesic, the main ingredients are aminopyrine, finasteride, caffeine and phenobarbital, of which aminopyrine and finasteride are antipyretic and analgesic, and their mechanism of action is similar to that of ibuprofen. Caffeine is a central stimulant that excites the central cerebral cortex and constricts cerebral blood vessels, and phenobarbital is a sedative-hypnotic with sedative, hypnotic and anticonvulsant effects, both of which can enhance the analgesic effects of aminopyrine and finasteride, and phenobarbital can also prevent fever-induced convulsions.

Aminopyrin and finasteride are more toxic, and aminopyrin can cause not only excessive sweating, rash, fever, stomatitis and sore throat, but also exfoliative dermatitis, neutrophil deficiency, glans eruption, aplastic anemia and other serious side effects. Finasteride can damage the kidneys, and in severe cases, it can lead to renal papillary necrosis, interstitial nephritis, pyelonephritis, cystinosis, liver damage, retinal damage, hemolysis, and in a few patients, it can induce pyelonephritis, bladder cancer, acute renal failure and uremia, and it can also cause dependence on finasteride with prolonged use.

In Europe and the United States, aminopyrine and finasteride were banned decades ago or used only as veterinary drugs, and the Ministry of Health of China promulgated the elimination of single-party preparations of aminopyrine and finasteride in 1982; however, compound antipyretic and analgesic medicines such as analgesic tablets containing the above ingredients are still in use, and so these compound preparations should never be abused. At present, the clinical indications for the use of analgesic tablets are that they should be used only when the condition is critical and there is no other effective drug treatment, which is almost impossible to happen nowadays when the supply of medicines is complete, so the analgesic tablets have already been withdrawn from the stage of history.

Finally, while ibuprofen has common gastrointestinal side effects and occasional neurological side effects, painkillers can cause granulocyte deficiency, necrosis of the renal papillae, and even induce renal pelvic and bladder cancers, and can lead to dependence with long-term use. Therefore, painkillers have more side effects and should never be abused.

The first thing that is clear is that the side effects of Depakote are greater than those of ibuprofen. A brief description of the clinical uses and adverse effects of both drugs follows:

Depakote: It is a compound preparation, which belongs to non-steroidal anti-inflammatory drugs and is used for fever and mild to moderate pain. Because it contains ingredients of aminopyrine and finasteride, the former can cause rash, vomiting, profuse sweating, fever and stomatitis, etc., and a small number of patients can develop exfoliative dermatitis, aplastic anemia, granulocyte deficiency, etc.; the latter can cause hemoglobin to form methaemoglobin, and cyanosis, and also cause liver damage, hemolysis, and some toxicity to the retina.

Ibuprofen: also a non-steroidal anti-inflammatory drug (NSAID), it is mainly used for the relief of mild-to-moderate pain as well as fever caused by the common cold or influenza; the main adverse effects are nausea, vomiting, dyspepsia, dizziness, headache, gastrointestinal ulcers, and hemorrhage, which are seen in a small number of patients only.

Comparison of painkillers and ibuprofen: both belong to non-steroidal anti-inflammatory drugs, because painkillers are compound preparations containing special ingredients, the incidence of adverse reactions and the severity of significantly higher than ibuprofen; painkillers are not recommended for use in children, while ibuprofen can be used for children, and both are prohibited to be used in pregnant women and lactating mothers; both are used for both pain relief and fever, are not recommended for long-term use, as both are only symptomatic drugs, generally not more than one day. Generally, the pain should not be taken for more than 5 days, and the fever should not be reduced for more than 3 days; because of the high incidence of adverse reactions of aminopyralid and finasteride contained in painkiller tablets, which can be replaced by other similar medicines, many countries have already stopped using the medicines containing the above ingredients, which are still being used in our country, and it is recommended that the patients should not use the medicines privately, and they must use the medicines under the close supervision of healthcare personnel.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

　　Depakote and ibuprofen are commonly used painkillers in daily life, both are non-steroidal anti-inflammatory drugs (NSAIDs), and long-term use of both may bring about some of the side effects common to this class of drugs. The most common is digestive side effects, the drug stimulates the gastrointestinal mucosa caused by digestive discomfort, such as heartburn, indigestion, nausea, bloating, diarrhea and stomach pain. Secondly, long-term use of the drug causes a decrease in platelet function, leading to bleeding, these non-opioid analgesics have the effect of preventing platelet aggregation. Therefore, long-term use is prone to increase the risk of bleeding, the more common is gastrointestinal bleeding. In addition, a small number of patients also experience fluid retention and swelling, an increased risk of kidney impairment, and an increased risk of heart disease and vascular disease. In comparison, painkillers have more side effects.

　　(1) From the viewpoint of chemical composition, Pain Relief Tablets belong to compound preparation. Each tablet contains 0.15g of aminopyrine and finasteride, 0.05g of caffeine, 0.015g of phenobarbital, aminopyrine and finasteride are non-steroidal anti-inflammatory drugs with antipyretic and analgesic effects. Caffeine is a central excitatory drug, which can assist in enhancing the analgesic effect. Phenobarbital component has sedative-hypnotic effect.

　　If a patient uses the drug for a long time, the aminopyralid in it may cause vomiting, rash, fever, profuse sweating and the occurrence of stomatitis side effects appear. In addition, the drug causes renal papillary necrosis, interstitial nephritis and the occurrence of acute renal failure is more likely than ibuprofen. Finasteride in the composition of the drug also tends to cause hemoglobin to form methemoglobin, which reduces the oxygen-carrying capacity of the blood and leads to cyanosis, and can also cause hemolysis, liver damage, and a certain degree of toxicity to the retina. The caffeine component of painkillers is prone to drug addiction, and the harm is relatively great. This drug has been eliminated in Europe and the United States.

　　(2) Ibuprofen is a propionic acid derivative, a single non-steroidal anti-inflammatory drug, by inhibiting the synthesis of prostaglandins to play the role of antipyretic and anti-inflammatory. From the use of the object, ibuprofen can be used for children, especially infants and young children with high fever can be used under the guidance of the doctor according to the weight of the ibuprofen granules; but the pain tablets can only be used for adults, not as a child's medicine, which is enough to show that the pain tablets have a great side effect. Although the effect of ibuprofen on blood clotting is smaller than other NSAIDs, it should not be combined with anticoagulants without close monitoring by a physician.

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Analgesic tablets and ibuprofen are two types of antipyretic and analgesic medications that can be used to treat fever and a variety of mild to moderate pain. However, they are significantly different in terms of their chemical composition, application population and safety. Here is a brief description of the differences between the two drugs."Liu pharmacist words medication", click the upper right attention, more rational use of knowledge to share with you!

The two have different chemical compositions

Degludec Tablet, also known as Soma Pain Tablet, is a compound preparation. Each tablet contains 0.15g of aminopyrine and finasteride, 0.05g of caffeine, and 0.015g of phenobarbital, both of which are non-steroidal anti-inflammatory drugs with antipyretic and analgesic effects. Caffeine is a central excitatory drug that can assist in enhancing the analgesic effect. Phenobarbital, also known as luminal, has a sedative-hypnotic effect and improves the response to painful stimuli. Ibuprofen, a propionic acid derivative, is a single non-steroidal anti-inflammatory drug that exerts antipyretic, analgesic and anti-inflammatory effects by inhibiting prostaglandin synthesis.

The two are different in terms of safety

1 Aminopyralid and finasteride have been phased out in the United States due to severe adverse effects

Although both drugs contain NSAIDs, the aminopyralid and finasteride in painkillers are foreign varieties that were phased out. Aminopyralid was first marketed in Europe in 1897, but later it was found to cause severe leukopenia, which led to a variety of serious infections and could be fatal, in 1938, the United States will be deleted from the list of legal drugs; finasteride was also a widely used antipyretic and analgesic, because of its increase in the risk of renal disease in the user and led to hundreds of deaths from chronic renal failure, in 1982, the United States FDA announced the discontinuation of the use of the drug containing finasteride in the prescription. In 1982, the FDA announced to stop the use of drugs containing finasteride in the prescription. However, compound preparations containing the above two ingredients still exist in China's pharmaceutical market, such as APC, analgesic, painkillers, due to the better efficacy of these drugs, low price, in some remote grassroots level is still in the application.

2 More serious adverse reactions occur with painkillers

A total of 62 literature reports on adverse reactions caused by depakote tablets were searched from 1983 to 2015 using "depakote tablets" and "soma pain tablets" as search terms in the Chinese Periodicals Full Text Database (CNKI). Among them were those causing acute kidney injury, gastrointestinal bleeding, exfoliative dermatitis, anaphylaxis, acute granulocyte deficiency, aplastic anemia, and a few cases of casualties were reported. Although ibuprofen has also been reported in terms of gastrointestinal reactions and skin rashes, it is generally milder and has a better prognosis. And ibuprofen can be used in children over 6 months of age.

3 Painkillers are addictive

Since phenobarbital is a sedative-hypnotic drug, taking it for a long period of time makes it easy to become addicted and develop tolerance, and it is necessary to keep increasing the dose in order to obtain the original therapeutic effect. In addition, finasteride is also addictive. Some patients with chronic pain for more than three to five years, will be inseparable, the longer the time, the more serious addiction. Ibuprofen has not been found to have addiction reports.

To summarize, the adverse effects of analgesic tablets are more numerous and serious, and their application should be avoided as much as possible when there are substitutable alternatives. Ibuprofen has relatively mild adverse effects and is one of the most commonly used antipyretic and analgesic drugs in clinical practice. However, when applying it, it is necessary to pay attention to the application time limit, for fever generally not more than 3 days, for analgesia, generally not more than 5 days, in order to avoid adverse reactions or delayed condition.

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The pharmacist's answer to the question of which side effects are greater, Depakote or Ibuprofen, is that both have side effects, but comparatively speaking, Depakote has more side effects and is relatively more severe.

Adverse effects of ibuprofen

The main adverse effects of ibuprofen are gastrointestinal, including vomiting, heartburn or, in a few patients, nausea, mild dyspepsia, gastrointestinal ulceration and bleeding, elevated aminotransferase, headache, dizziness, tinnitus, blurred vision, nervousness, drowsiness, lower extremity edema, or sudden weight gain.

Ibuprofen rare rash, allergic nephritis, cystitis, nephrotic syndrome, renal papillary necrosis or glancing failure, bronchospasm.

Ibuprofen is a relatively safe antipyretic and analgesic anti-inflammatory drug.

Small doses can be used to relieve fever, and a common commercially available preparation is ibuprofen suspension, which is used to reduce fever in infants and children over two years of age, as well as in adults.

Medium doses can be used for antipyretic and analgesic purposes, and a common commercially available preparation is ibuprofen extended-release tablets (0.3 g a tablet), which can be used to relieve fever caused by colds, as well as headache, toothache, arthralgia, and menstrual cramps.

Large doses have antipyretic and analgesic and anti-inflammatory properties and can be used in the symptomatic treatment of osteoarthritis.

Adverse Reactions to Painkillers

Depakote is a combination of aminopyrine, caffeine, finasteride, and phenobarbital.

It is no longer used as a routine antipyretic and analgesic because of its high number and severity of adverse effects.

So, a special reminder from the pharmacist:Use antipyretic and analgesic medications safely, reduce the use of painkillers, and use relatively safe antipyretic and analgesic medications, such as preparations containing ibuprofen and preparations containing acetaminophen.

Dexedrine side effects are noticeable adverse reactions produced primarily by the aminopyrine and finasteride contained.

Aminopyrin can produce vomiting, rash, fever, profuse sweating and stomatitis, and in a few cases, neutrophil deficiency, aplastic anemia, exudative erythema, exfoliative dermatitis, and glans eruption.

After taking finasteride in large quantities for a long time, it can lead to renal papillary necrosis, interstitial nephritis and acute renal failure, and may even induce renal pelvic cancer and bladder cancer, and may also cause dependence on the drug. Finasteride also tends to make hemoglobin form methemoglobin, which reduces the oxygen-carrying capacity of the blood and leads to purpura, and can also cause hemolysis, liver damage, and has a certain degree of toxicity to the retina.

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I have been taking painkillers and ibuprofen for 10 consecutive days because of periodontal and pulpal inflammation. It is a drug that has side effects, as to which side effects, should be different from person to person, I recently to the evening on the leg soft, aching, like a cold symptoms, but absolutely no cold, see you this question, there is a realization, it should be due to these two kinds of drugs for a long time to take!

Before answering this question get the right idea about adverse drug reactions

Adverse Reactions (ADR)In addition to treating your illness, qualified medicines may cause you some discomfort during normal use, also known as "side effects" to the general public. Side effects are common to all medicines, but they do not happen to all people who use them. Some side effects may disappear during the course of the medication, but when you experience a side effect that affects your life, you should talk to your doctor or pharmacist about it.

I. Differences between the two

II. Different modes of access to the two

The painkillers areprescription drugs

Ibuprofen isnon-prescription drug

In layman's terms, the difference between prescription and over-the-counter medications can be made in terms of both the performer and the characteristics of the drug:

prescription drugsIt is a pharmaceutical drug that must be prescribed by a doctor who has a licensed physician or a licensed physician assistant's license. For new drugs that have just come on the market, drugs that have a dependency effect after taking them, drugs with high toxicity and side effects, as well as some drugs for treating special diseases, they are basically prescription drugs;

Over-the-counter (OTC)In other words, it is a drug that can be judged, purchased and used on its own without a physician's prescription, and patients can make their own judgments and go to a pharmacy or buy drugs online without a doctor's guidance for the relief of minor, short-term ailments and discomforts.

III. Differences in drug safety

Depakote has more serious adverse reactions and side effects, may cause acute kidney injury, gastrointestinal bleeding, anaphylactic shock, acute granulocyte deficiency, exfoliative dermatitis, aplastic anemia and other serious adverse reactions, prolonged use and easy to become addicted, but also to develop tolerance.

Ibuprofen may occasionally have gastrointestinal and rash adverse reactions, but generally there is no serious illness, and there is no addiction, from the analgesic effect is also better than the effect of painkillers, so it is more commonly used in the clinic, and can even be taken by children over the age of 6 months.

In cases where both medications can treat your pain, the safer ibuprofen is recommended

First of all, the side effects of drugs are caused by the low selectivity of drugs in the body, basically, we can say that all drugs have side effects, but the drugs are used reasonably in the case, there are certain side effects, but they will not cause too much harm to the body.

Side effects of ibuprofen

1 Mainly in the gastrointestinal tract, a few patients may experience nausea, vomiting, heartburn, or mild dyspepsia, gastrointestinal ulcers and bleeding.

2 Few patients with headache, dizziness, tinnitus, blurred vision, nervousness and other adverse reactions.

De-pain tablets are compounded with the components of aminopyrine, finasteride, caffeine, and phenobarbital. De-pain tablets have more ingredients and relatively more side effects.

1 Long-term use of painkillers can lead to kidney damage, which can seriously lead to renal papillary necrosis or uremia, or even induce bladder cancer.

2 Long-term use can lead to dependence and tolerance.

3 Vomiting, fever, profuse sweating, and stomatitis may occur, and in a few cases, aplastic anemia, exudative erythema, and glans erosion may occur.

4 Causes cyanosis, as well as hemolysis, liver damage, and some retinal toxicity.

To summarize, the side effects of pain relief tablets are much greater than those of ibuprofen. Caution should be exercised in the use of pain relief tablets, especially if taken for a long period of time.