1, avoid tobacco and alcohol. Alcohol will cause the normal enzyme system of liver cells to be disturbed and destroyed, which will directly damage liver cells and make them necrotic, so that the patient's health will be affected.

　　2, avoid indiscriminate use of supplements. Balanced diet is to maintain the basic conditions of health, hepatitis B patients with elevated aminotransferases if the nourishment is not appropriate, back to jeopardize the health of the body.

　　3, keep a happy mood. Keep a positive mindset will live a long time, usually learn to restrain their temper, even if they are angry, not more than 5 minutes, to be positive and optimistic, keep a happy mood.

　　4, avoid processed food. We must eliminate eating food with preservatives in our life, which is not good for our body. Elevated transaminases should eat less canned or bottled drinks and food. Because these foods have added preservatives.

　　5, avoid abusing drugs. I believe we all know that drugs are three times poisonous, drugs on the liver and kidney damage, hepatitis B patients with elevated aminotransferases must be under the correct guidance of the doctor, reasonable use of medication.

Dr. Duan Q&A Online 🚀 Treatment of Elevated Transaminases 🚀

Transaminase is only an indicator to detect the disease, which itself is not harmful to the body, so lowering the enzyme is not the key to treatment, the focus is to find the cause of the disease and correct it, and according to the severity of the choice of appropriate liver and enzyme lowering treatment.

Sources of transaminases

Normally, transaminases are present in the cells and play a role in amino acid metabolism, while the blood contains only a very small amount (0-40 U/L) and has no role. When cellular damage is caused by certain reasons, transaminases are spilled, increasing the concentration of transaminases in the blood (>40 U/L), and the degree of elevation depends on the severity of the cellular damage.

The key to treating elevated transaminases is to find the cause of the disease

Hepatocytes have the most transaminases, followed by cardiac muscle, skeletal muscle, pancreas, and kidneys. Therefore, when transaminases are elevated, the first thing to consider is liver disease, and all liver diseases may cause elevated liver enzymes. For example, drug-induced liver injury requires stopping or reducing the dosage of drugs; hepatitis B and C require antiviral drugs; fatty liver requires diet and exercise changes; alcohol-induced liver injury means quitting drinking; various infections (bacterial, viral, etc.) require anti-infective treatments; and autoimmune liver diseases, among others, and there are many other liver diseases for which no cause can be found.

Of course, in addition to liver disease, there are other diseases of the organs, such as skeletal muscle damage, heart attacks, pancreatitis, etc.

The next treatment is - liver protection and enzyme reduction.

Doctors usually regard liver-protecting treatment as more important than enzyme-lowering. When the transaminase is 0～100U/L, if the cause of the disease is lifted, the transaminase will return to normal naturally, if the cause of the disease can not be lifted, it can be appropriate to take oral liver-protecting and enzyme-lowering drugs. When the transaminase is 100～200U/L, oral hepatoprotective and enzyme-lowering drugs will be fine. When the transaminase ≥200U/L, especially >300U/L, can consider the infusion of liver-protecting enzyme-lowering drugs.

Hepatoprotective and enzyme-lowering drugs include: ① Reduced glutathione, with good hepatoprotective effect, only infusion; ② Polyenphosphatidylcholine, to protect hepatocyte membranes, both oral and injectable; ③ Glycyrrhizic acid preparations, such as magnesium isoglycyrrhizinate, diammonium glycyrrhizinate, etc., with good enzyme-lowering effect, both oral and injectable. ④Biphenyldiphenyl ester, fast enzyme-lowering effect, but easy to rebound after rapid discontinuation, only oral medication. ⑤ Dicyclomine tablets, oral medication.

Dr. Duan specifically warned:

(1) In fact, to see whether the disease is serious or not, we cannot only look at the transaminases, but the doctor will also make a comprehensive judgment based on other items of liver function, and coagulation and blood lipids.

(2) Therefore, it is safest and most reliable to use the medication under a doctor's supervision.

(3) There are some conditions, such as fatty liver, where medications can do very little without addressing high blood lipids.

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First of all, thank you for your question.

The question of how to lower high aminotransferase is more general, aminotransferase is generally divided into many kinds of tests, such as alanine transferase and glutamyl transpeptidase and so on. High aminotransferase depends on the specific situation, combined with other laboratory indicators or imaging tests and the patient's clinical manifestations and symptoms. The following is only a brief description of the major aspects, but please note that it is only the possible causes. Only when the cause of the disease is clear, can we treat the symptoms, so it is recommended to go to a regular medical institution for a clear diagnosis.

The possible causes of high transaminases are: 1, viral hepatitis (e.g., hepatitis A, B, C), at this time the high transaminases may be the inflammatory stage of the liver with liver injury. At this time, timely antiviral treatment should be provided.2. Early manifestation of primary or secondary biliary cirrhosis. Such as cholelithiasis, cholecystitis, cirrhosis, hepatocellular carcinoma, etc. 3, drug liver injury, such as long-term improper use of a certain drug caused by 4, some patients may have elevated aminotransferase after chemotherapy. 5, patients with alcoholic liver, fatty liver. This kind of patients will also increase the level of alanine aminotransferase, but patients with fatty liver are accompanied by increased levels of cholesterol and triglycerides at the same time.

For how to lower aminotransferases, you need to accurately find the cause of the disease and just treat the symptoms. Transaminase is an important monitoring index of human liver function, and will be elevated in inflammation and poisoning. You can't simply judge the severity of the disease by the level of the transaminase value. People often mistakenly believe that a high transaminase is hepatitis or that a high transaminase is contagious, both of which are incorrect. It is not true that the functioning of the liver is only determined by the level of aminotransferases. And at the same time, it is recommended not to take medication on your own to avoid delaying the condition or bringing secondary damage, and should go to a regular medical institution in time for specialist consultation.

I hope the above answer can help you.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

　　Transaminases are categorized into alanine aminotransferase and glutamic aminotransferase, with the former being more commonly elevated. This enzyme is found in the cells of the liver, heart muscle, and kidneys, and is most abundant in hepatocytes, where it is released into the bloodstream and the index is elevated whenever hepatocytes are damaged.

　What should I do if my transaminases are high?

　　Transaminases do not usually rise for no reason, so when a physical exam reveals elevated transaminases, it should not be taken lightly and further investigation is needed to find the cause.

　　2 major factors can cause high transaminases!

　　High transaminases, by and large, may be caused by two reasons, one is physiological factors and the other is pathologic factors, and the response to different causes will be different.

　　Physiological causes of aminotransferase elevation: such as eating greasy food before the test, strenuous exercise, staying up late, poor rest, overwork, drinking alcohol, etc., or do not keep fasting for 8 hours before the test, these behaviors will cause the glutamic acid aminotransferase elevation, but will not be too much higher than the normal value.

　　These factors are usually avoided and the transaminases can return to normal after a period of time.

Pathological causes of transaminase elevation: like in daily life, the more common liver diseases, can cause high transaminase, and usually will be much higher than the normal value, this situation must be taken seriously.

　　The specific cause of high transaminases can be identified by examining virologic indicators, ultrasound, autoimmune antibody tests, and other tests.

　　High transaminases, it may be a signal of liver disease, must be taken seriously, do further examination, after the detection of the disease should be treated in time, so as to avoid aggravation of the condition, and sustained damage to the liver.

Well, this severe elevation of hepatitis aminotransferases is not a small thing, it can burn the liver. Hepatitis is terrible, but human prejudice and ignorance is more terrible than hepatitis, just like many of us who are sick don't know to reduce the burden on the body, but also labor with the disease, or don't know the dietary contraindications when they are sick.

We Chinese medicine, a person who understands the dietary taboos of his cure will have twice the effect with half the effort, a person who does not understand the dietary taboos, such as hepatitis people also eat fried barbecue, big wine and meat, that half the effort, but half of the effect can not be achieved, and even increase the pain of the disease ah!

So it's not that medicine doesn't work for lowering transaminases, it's that we don't keep up with our habits.

So we have to pay attention to liver five points. The first must go to bed early, go to bed early to nourish the kidney water, water is enough to calm the liver fire, water loss of wood dry fire from the fire, which is called wood dry fire theory.

That's why we often use white peony when treating the liver, why? It softens the Liver and calms the Liver's anger.

Secondly, we should use our eyes less. Excessive use of the eyes is pulling out liver blood. We now use the eyes of that frequency and degree of the ancients ten times a hundred times ah! So you see, even some children play games to the retina detachment, how powerful! So addicted to the Internet, games or computers, on the surface hurt the eyes, but actually hurt the liver.

Thirdly, alcohol can injure the liver, so if you drink too much alcohol, the function of the liver will be in a mess, completely messed up, called alcohol can mess up the sex. The nature of the liver is completely messed up, and after it is messed up, the normal metabolism cannot be maintained and is in disarray.

Fourthly, anger is able to cut down the wood, and every time you are angry, it is as if the wood of your liver has been cut by a knife. Therefore, anger toward others is like cutting oneself with a knife.

Those who are wise will know how to live a life without grudges. If they don't know how to live a life without grudges, it means that their cultivation and realm have not yet come up, and they haven't suffered enough.

And the fifth? The fifth is to be diligent in exercising. The liver is the main regulator of excretion. Why do the Chinese have a custom called March 3, kite flying? In spring, it is the time to detoxify the liver and relieve depression. When you fly a kite, you pull the kite and run, step on the grass, and then look up to the sky, which stimulates the Yongquan acupoints down below, and pulls through the Baihui, Shoulder Wells, and Daxi points up above, while looking up, the liver qi will be relieved!

In Chinese medicine, we say that all diseases are caused by depression of qi, so when a person sits in the office for a long time, he is a depressed elephant. Why do we have more and more hepatitis patients in China? Because sitting in the office hard to sit in the liver meridian gas to sit flat, sit blocked, so sedentary not only hurt the spleen, but also hurt the liver ah!

There are many causes of elevated transaminases, then the principle of treatment is also different. Common causes include viral hepatitis, such as hepatitis A, B, C, D, E and other hepatophilic viruses and EBV, casaki virus, and other non-hepatophilic viruses infections, there are non-alcoholic fatty liver disease, alcoholic liver disease, drug liver disease, autoimmune liver disease, hereditary liver disease, and metabolic liver disease and other causes. Elevated aminotransferases are closely related to hepatitis, but not only because of the liver, for example, AST elevation may be due to heart disease, ALP elevation may be due to children's bone development, so in order to determine whether elevated aminotransferases are hepatitis or not, it depends on which aminotransferases are elevated and the magnitude of elevation, which needs to be analyzed and considered in a comprehensive manner. In addition, not all hepatitis is contagious, only viral transaminases are contagious in the above mentioned causes, and the mode of transmission is not consistent, so if you find elevated transaminases, it is recommended that you go to a specialized hospital for further examination to clarify the condition.

If the transaminase elevation is caused by viral hepatitis (including hepatitis B and hepatitis C), active antiviral and anti-inflammatory hepatoprotective treatments are needed. If the transaminase elevation is caused by medication, it is necessary to stop using the suspected medication and apply hepatoprotective medications immediately. If the elevation of aminotransferase is caused by alcohol consumption, it is necessary to stop drinking immediately and apply appropriate liver-protecting drugs. Autoimmune liver disease also requires treatment with hormones or ursodeoxycholic acid, depending on the condition. Therefore, if you are not sure what causes the elevated transaminases, it is recommended to clarify the condition and then actively treat it according to the situation.

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Elevated aminotransferases are just one manifestation of liver damage, and simply lowering the enzymes certainly helps to reduce liver inflammation, but it does not address the underlying issues that lead to liver damage.

Commonly used drugs to reduce transaminases are mainly glycyrrhizic acid preparations, such as Tianqing Ganping capsule, Mennen tablets, Tianqing Ganmei, etc. There are also some other proprietary Chinese medicines with certain enzyme-lowering effects, such as ginseng astragalus and schizandra.

Many people in the examination of the body found that the serum transaminase value is elevated, and is recognized as the body for the physical health status is not qualified for further education, employment, military and other restrictions; there are also some people who mistakenly believe that elevated transaminase is viral hepatitis, there is contagious, once found that the transaminase is elevated, often panicked, and seek medical attention. In fact, there are many reasons for transaminase elevation, some causes of elevation, may be transient, short-lived, not much effect on the body; some causes of elevation is long-lasting, more damaging to the body. Therefore, after the discovery of elevated aminotransferases, the first thing you need to do is to identify the cause of the elevation before you can reasonably deal with the cause of the disease.

The most important aminotransferases in human blood are alanine aminotransferase (ALT) and mentholatum aminotransferase (AST), which are most commonly found in hepatitis caused by various etiologies, and are especially elevated in acute hepatitis, such as viral hepatitis, drug-induced hepatitis, alcohol-induced hepatitis, infectious-toxicity hepatitis, cirrhosis of the liver, and hepatocellular carcinoma. Others such as biliary tract inflammation, fatty liver, leptospirosis, schistosomiasis, liver fluke, malaria, and so on. Significant elevation of aspartate aminotransferase is also seen in the acute stage of myocardial infarction, myocarditis, myositis, progressive muscular dystrophy, acute pancreatitis, and so on. Acute pancreatitis, etc. Therefore, elevated serum aminotransferase activity is not always viral hepatitis, and must be combined with the history, symptoms and viral markers test comprehensive judgment, in the exclusion of other diseases, in order to make a correct diagnosis. Although there are many causes of elevated transaminases, the vast majority of incidental findings are subclinical or mild forms of hepatitis in the latent state. The most common conditions, in order of prevalence, are fatty liver, alcoholic hepatitis, chronic hepatitis B, chronic hepatitis C, strenuous exercise and overexertion, chronic inflammation of the gallbladder, and drug-induced liver damage. Therefore, if you find that your aminotransferases are elevated, the first thing you should do is to consider the following 6 factors and conduct relevant and targeted tests to understand the cause:

1. Blood tests for liver function series are drawn:(including aminotransferase, bilirubin, serum protein ratio, etc.), hepatitis virus full item, hepatitis B disease department markers (three systems), if the viral indicators are positive, need to do another review, if still positive, can be diagnosed as fruit some viral hepatitis.

2. Weighing:Look to see if you are overweight, and if you are overweight, you are likely to have a fatty liver. Because elevated aminotransferases are quite common with fatty liver, and are often accompanied by elevated levels of lipids (cholesterol, triglycerides, etc.), an ultrasound or CT scan can help make the diagnosis.

3. Pay attention to living and eating habits:Is there a habit of drinking alcohol regularly, whether it is liquor or beer. Because chronic alcohol consumption can cause alcoholic hepatitis, characterized by an enlarged liver and symptoms of pain in the liver area. And co-exist with fatty liver. Whether you have been too tired lately or have participated in strenuous exercise, as overwork can also cause elevated transaminases.

4. review the relevant medical history:Have a history of blood or blood product transfusions, surgery, trauma, and if so, be sure to check for the presence of Hepatitis C. If there is a person with hepatitis B in the immediate or collateral family, especially a parent, be sure to check the hepatitis B tri-system to rule out the possibility. Past illnesses such as cholecystitis, heart disease, and nephritis can also cause elevated transaminases.

5. History of medication:If you have recently taken medications that are damaging to the liver, such as the Chinese herbs hemicrania, neem, and shan ci gui, the Western medicines anti-tuberculosis, antibiotics, anti-rheumatic drugs, etc., if so, be sure to watch out for the possibility of medication-induced hepatitis.

6. The special situation of women:Women should also be aware of the possibility of autoimmune hepatitis and should be checked for positive autoimmune antibodies (antinuclear, antimitochondrial, anti-smooth muscle, etc.).

Overall, there are many causes of elevated transaminases, which must be carefully examined and diagnosed one by one before treatment. Regarding the treatment of transaminase elevation, firstly, it emphasizes on removing the cause and treating the cause, such as patients with viral hepatitis, they should be treated with antiviral therapy, the more ideal antiviral drugs for hepatitis B are lamivudine and entecavir, and for hepatitis C, it is interferon. Alcoholic hepatitis caused by transaminase elevation, mainly to quit drinking. In addition, herbal enzyme-lowering preparations can rapidly reduce the transaminase, the effect is also better, such as schizandra preparations, biphenyl dibenzoate, liver, glycyrrhizic acid preparations, but these drugs can only play a "symptomatic" purpose, to solve the surface phenomenon of transaminase elevation, but can not solve the root cause of transaminase elevation. Therefore, the treatment of elevated aminotransferases requires both "symptomatic and fundamental" treatment, removing the cause of the disease on the one hand, and using enzyme-lowering drugs on the other.

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42-year-old teacher insisted on liver health, half a year transaminase from 396 to 28, 2 methods worth studying

Sister Zhou in our neighborhood this year 42 years old, engaged in the work of the teacher, has a happy marriage envied by people, children, children, work is also very stable, is a typical happy life of a class of people. But recently Zhou sister whole person looks sullen, and often during the day is not energetic, do not be able to concentrate on what to do. It was only when I asked her about it that I realized that she had liver problems.

After a detailed diagnosis by my doctor, I realized that I had eaten too much of something that was hurting my liver.

Three kinds of liver harming foods to stay away from, don't get liver cancer before you know to cherish it

1、High fat food

If you want to protect your liver, don't eat too much high-fat food during your diet. Fat-rich foods often get the risk of affecting the health of the liver, because too much access to fat is easy to make the body fat, obese people body fat material accumulation, easy to let the liver cells are infiltrated with fatty substances, and then increase the prevalence of liver disease, is the reason why some people fatty liver appeared.

If you can avoid this misbehavior, those fatty substances rich in fat meat eat less, not only can control weight, but also to avoid excessive access to calories to make the body fat, but also reduce the pressure of digestion, maintain a normal appetite.

2. Sweets

Now that living conditions are better, sweets have become an after-dinner snack. In almost all sweet foods, there are large amounts of sweeteners made from white sugar or syrup. The metabolism of sugar in the human body requires the assistance of the liver, and the whole process consumes a variety of energy. Moreover, excessive sugar intake will result in increased metabolic burden on the liver. Energy is converted to fat storage, inducing fatty liver, so fat people first fat liver, this is the reason.

3. Heavy seasonings such as chili peppers and peppercorns

Into the winter, hot pot has become a lot of people's first choice, and in the usual time to eat hot pot, will often choose some dipping sauce, pot base and other food, but for some of the body of the liver fire or suffering from hepatitis of the crowd, as little as possible to eat hot pot in normal times, and for some spicy and other heavy flavors such as spices is also as little as possible to eat.

If consumed in large quantities, it may also lead to increased dampness in the body, which in turn affects the repair of liver cells and is also very detrimental to the liver, so try to eat as little of this food as possible in the winter, and your liver may be grateful to you.

Transaminases dropped from 396 to 28 in 6 months, and these 2 methods are worth learning for everyone

The culprit of all this Zhou sister is also clear, in the feeling of the body is not right at the very beginning she went to the physical examination, the results of the examination is obvious, Zhou sister's liver problems, damage is serious, the normal value of aminotransferases should be below 40, but Zhou sister's surprisingly up to 396. The doctor is also warned her, if you do not take care of this state, one or two years will be cirrhosis of the liver risk.

Really scared Zhou sister, then in the doctor's advice to prescribe some "medicine" to adjust, but the body's aminotransferase is always high and low, and finally there is no way out, in the friend's introduction to find a Chinese medicine experts, to seek help.

Chinese medicine experts to Sister Zhou using the preparation is actually very simple, he is mainly taken from Li Shizhen "Materia Medica" in a classic soup, the formula see - (wu) bare mountain Zhi 3 grams, Tibetan bearded hemp 5 grams, goji berries 8 grains, one dose per day, boiled water, soaked in water to serve.

Not long ago, there is one thing that makes Zhou's family overjoyed, it turns out that when she went to the hospital again for a review, the doctor was surprised to find that all the indicators in her body are back to within the normal range, the transaminase has also dropped from more than 300 to 28 to return to normal, in other words, nowadays Zhou has no difference with the normal people.

Modern pharmacological studies have analyzed that Bare Mountain Chi can help damaged livers to enhance the activity of liver cells and inactivate many free radicals that are harmful to liver health, so as to maintain the efficacy of the liver.

It is rich in selenium in the medical profession has been enjoying the reputation of "liver factor", its inhibition rate of hepatitis B is as high as 95% or more, and with the goji berries and Tibetan hemp can play a good role in enhancing the patient's own immunity to help, immunity as the first line of defense of our body, only it is strong enough to resist the Foreign invasion.

Method 2: To eat sensibly

If transaminases are elevated during a physical examination, especially in young and middle-aged people, they should be given high priority and should be regulated by diet.

We all know that the liver secretes bile to participate in the digestion of fat, if you eat a lot of meat and fish all day long, it will increase the burden of liver secretion, if coupled with the usual low physical activity, do not actively participate in sports, and get a fatty liver, under the action of these two factors, liver damage is inevitable. Therefore, the diet should be light, pay attention to follow their own physical condition to carry out appropriate physical exercise, this is a good way to prevent and reverse the transaminase elevation.

What about high liver function transaminases?

High liver function transaminases should be examined to determine the cause of the elevation and then treated for the cause.

If the transaminase is only mildly increased and there are no other symptoms, it may be physiological elevation, such as strenuous exercise, irregular work and rest, alcohol, greasy diet, nutritional deficiencies, too much fatigue, taking some medications, or even emotional fluctuations, and so on, can be adjusted to adjust the habits, for the adjustment of the 1-2 weeks after the review may be back to normal. However, if the transaminase is elevated to a greater extent and other symptoms appear, accompanied by a number of indicators of abnormalities, which can be seen in viral hepatitis or other liver diseases, it is necessary to pay attention to, should immediately consult a doctor to seek treatment.

In conclusion, there are many reasons for elevated aminotransferases, and other tests such as liver ultrasound or CT should be performed to analyze the cause of elevated aminotransferases in conjunction with the history, symptoms, and signs of the disease, and then treat the cause of the elevated aminotransferases.

Reviewed by Dr. Li Xiaolin, Chief Physician, Department of Gastroenterology, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine, China

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