Doctor, does this medicine you gave me have hormones? I don't want to use hormones, I heard from others that it is very harmful to my body! Also, if you use too much hormone, you will become dependent!

• Androgens: besides making boyfriends pop, it also works to promote hair growth and boost blood production. So hair loss and anemia could be related to androgen deficiency.
• Estrogen: makes the skin smooth and promotes the development of female secondary sexual characteristics. Estrogen may be added secretly in breast enhancement creams. The secretion cycle of estrogen also determines a woman's menstrual cycle.
• Progesterone: It is secreted like crazy when you are pregnant, causing a series of changes in the mother's body and maintaining the pregnancy until the baby is born.

What are the side effects of hormone medications?

Hormone drug side effects depend on which specific hormone drug is being looked at. For example, with glucocorticoid medications, side effects include Cushing's syndrome, withdrawal reactions, and inducing or aggravating peptic ulcers.

Cushing's syndrome is caused by long-term use of hormone drugs that exceed physiological needs, with symptoms such as full-moon face, centripetal obesity, buffalo back, hypercholesterolemia, hyperglycemia, muscle atrophy and weakness, osteoporosis, acne, susceptibility to infections, hypokalemia, high blood pressure and edema. Withdrawal reaction is easy to cause after long-term use of drugs suddenly stopped, the symptoms of the original disease can be seen to reappear or even aggravate, also known as the "rebound phenomenon", in addition, there are some patients in a short period of time with a large number of hormone drugs, such as the sudden withdrawal of the drug, may also appear mental depression, fever, nausea, vomiting, fatigue, myalgia, arthralgia and other symptoms. Another example is estrogen drugs, whose side effects include abdominal cramps or flatulence, poor appetite, nausea, ankle and foot edema, breast distension or swelling, weight gain or loss, irregular vaginal bleeding, spotting, breakthrough bleeding, prolonged bleeding or amenorrhea, drowsiness, frequent urination, pain with urination, and severe or sudden headaches.

This content was reviewed by Deqiang Li, Deputy Chief Pharmacist, Department of Pharmacy, The Second Hospital of Hebei Medical University.

Click here for details of the doctor's answer

Adverse effects of glucocorticoids are usually dose-related, and many increase with the duration of treatment, even with small doses of glucocorticoids. Side effects are one type of adverse drug reaction, and the following is a brief summary of common adverse reactions to glucocorticoids:

1. Common adverse reactions include weight gain and Cushing-like manifestations, skin thinning and purpura, sleep disturbances, and altered state of mind. Patients using higher doses of glucocorticoids may experience cognitive changes, dysphoria, and in a few cases, psychiatric symptoms.

2. Cataracts are common with prolonged glucocorticoid application (usually more than 1 year) and are dose- and duration-dependent. Increased intraocular pressure is dose-dependent but is also influenced by other risk factors.

3. For some populations there is evidence of increased risk of cardiovascular disease.

4. Small doses of glucocorticoids can also lead to increased blood pressure and can cause peripheral edema and fluid retention.

5. The increased risk of peptic ulcer disease and gastritis in glucocorticoid-treated patients is mainly seen in those who are also on nonsteroidal anti-inflammatory drugs (NSAIDs). These patients should receive appropriate prophylactic therapy (e.g., oral proton pump inhibitors).

6. Skeletal and muscle-related adverse reactions may occur, including osteoporosis, osteonecrosis, increased risk of fractures, myopathy, and effects on skeletal development and growth in children.

7. Immunosuppression and its resulting increased risk of infection. Patients receiving moderate to high doses of glucocorticoids should generally not receive live virus vaccinations to prevent further infection.

Patients using glucocorticoids should be aware of the following:

1. Treat pre-existing coexisting conditions that may increase the risk of adverse effects when glucocorticoids are required.

2. Use the smallest dose of glucocorticoid of the shortest duration necessary to achieve the therapeutic goal.

3. Monitor for possible serious adverse reactions.

Na Cun, Clinical Pharmacy Office, Affiliated Hospital of Chifeng College, Member of the Pharmacy Network

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

In fact, there are many kinds of "hormone drugs", but the common people generally say "hormone" is adrenal glucocorticoid hormone, in order to cater to the inherent cognition of the majority of the people, the following "hormone In order to cater to the inherent cognition of most people, the "hormones" mentioned in the following are specifically adrenal glucocorticotropic hormones.

Today, we will count the "side effects" of hormones:

Side effect number one: fat.

Although "a fat ruin all, other need not talk about". But this "fat" and general fat is really not the same, this is a kind of "full moon face, buffalo back, thin limbs, thin skin, sweat hair" fat.

This is due to hormones affecting fat metabolism, resulting in the redistribution of fat throughout the body caused by, in addition, because of excessive hormones inhibit protein synthesis, but also cause muscle atrophy, so this fat is a big face, body fat, relatively thin arms and legs fat.

However, you do not need to worry too much, this is usually a long-term, large amount of hormone use will appear, never use once or twice, or short-term use of hormones can cause. Moreover, these symptoms will slowly improve after stopping or reducing the amount of hormones. As for some people who can't regain their body shape for a long time after using hormones, it's because during the use of hormones, it will increase people's appetite and enhance the amount of meals, and after stopping the drug, it's difficult to lose weight because of the habit of eating more. Therefore, if you stop taking the drug but can't lose weight, it's mostly because you can't control your own mouth, not because of the crime of "excitement".

Side effect 2: Increased blood sugar and blood pressure

As you can see from the previous science, it is caused by hormones affecting the metabolism of sugar, water and electrolytes (salts). Hormones reduce the consumption of sugar and increase its production and intake, which raises blood sugar; they reduce the excretion of salts, and in order to dissolve these salts, the body has to retain more water to dissolve the salts, and with more water in the blood vessels, the pressure is higher. Again, these symptoms generally resolve slowly after the hormones are discontinued or tapered.

Side effect three

Triggers or exacerbates peptic ulcer disease

Because hormones have the effect of promoting the secretion of gastric acid and pepsin (a type of digestive enzyme), excessive secretion of gastric juices will increase the irritation of gastric juices on the inner surface of the stomach and intestines, resulting in ulcers. Therefore, once you use hormones, regardless of whether or not you have had stomach problems before, your doctor will usually add medication to inhibit gastric acid and protect the gastric mucosa. This is really not to earn more money!

Side effect IV

Causes osteoporosis and abnormal bone development in children

Long-term use of hormones can lead to osteoporosis, and the bones of the spine are more susceptible, which can lead to low back pain and even fractures. Because hormones can affect the metabolism of calcium and phosphorus, increase the excretion of calcium and phosphorus, and inhibit the vitality of the cells that make bone (osteoblasts). Prolonged, high-dose hormone use can easily induce femoral head necrosis.

Side Effect #5 Inducing or Exacerbating Infections

Due to the immunosuppressive effect of hormones, it can lead to a weakening of the body's immune response (as the author's previous science said, the security guards were called off), which can trigger an infection or lead to the spread of the infection. Therefore, in the treatment of some infectious diseases with more inflammation and exudation, such as tuberculosis, doctors will use effective anti-tuberculosis drugs and then add hormones to kill germs at the same time, but also reduces the inflammatory response, the real "fish and bear's paw" are given to you!

Side Effect #6 Induces psychosis and epilepsy

Because hormones have the effect of excitation of the central nervous system, and the basic cause of epilepsy is the symptoms caused by abnormal excitation of the central nervous system discharge, some psychiatric symptoms some are also due to the nerve excitation of the new too high, so patients with a history of epilepsy or psychiatric illnesses, the doctor will not generally use hormones as a last resort, and if they do use them, they will also be done in advance to take precautionary measures. Therefore, if you have a history of epilepsy, you must inform your doctor truthfully when you seek medical treatment to avoid unnecessary danger.

Hormones do have a lot of side effects, but their powerful anti-inflammatory, immunomodulatory and other effects are also hard to replace! That's why doctors often say that hormones are a double-edged sword that needs to be weighed and judged by a medical professional and used when the benefits outweigh the drawbacks.

For example, patients with autoimmune system disorders that are not treated with hormones can lead to rapid deterioration or even death, and for some people with life-threatening shock, hormones can sometimes even go as far as to bring the dead back to life.

How do you decide on side effects versus saving your life?

Even if there are side effects from the use of hormones, there is still room for remedies. Most side effects go away when the medication is discontinued, and it is very rare to need to use hormones for long periods of time and in high doses. Many serious side effects do not come from the hormones themselves, but from the irrational use of hormones over a long period of time.

That's why we have to - follow the doctor's advice and strictly prohibit the blind use of hormones on our own!

Hello, I am a pharmacist in charge and I can help you with this question.

There are many types of hormones, but the hormones that are commonly referred to are the adrenocortical hormones, such as glucocorticoids and salocorticoids. There are also sex hormones such as androgens and estrogens, progesterone, thyroid hormones, and insulin.

Glucocorticosteroids are the most widely used adrenocorticosteroids in clinical practice and are generally used for anti-inflammatory and immunosuppressive purposes.

Why are glucocorticoids called glucocorticoids?

Glucocorticoids are endogenous substances that are self-contained in the body and are secreted by the zona fasciculata of the adrenal cortex, and are named glucocorticoids because they regulate the metabolism of sugar.

What are the side effects of glucocorticoids?

Prolonged heavy use of glucocorticoids can lead to high sodium, low potassium, low calcium, high blood sugar, full moon face, buffalo back and centripetal obesity. There is also acne, hirsutism, hypertension, hyperlipidemia, amenorrhea and osteoporosis.

Why do glucocorticoids have these side effects? We can understand this by looking at the physiologic effects of glucocorticoids.

Glucocorticoids are involved in the process of bringing down a variety of substances in the body, such as sugars, proteins, fats, water and electrolytes.

1. Protein

Glucocorticoids promote proteolytic metabolism and inhibit protein synthesis, which can lead to negative nitrogen balance.

Side effects: Long-term use of glucocorticoids in large quantities can cause severe muscle atrophy, osteoporosis, slow wound healing, and affect the growth and development of children.

2. Sugar

Glucocorticoids elevate blood sugar and increase glycogen levels.

2.1 Elevation of blood glucose: Glucocorticoids inhibit the utilization of glucose by peripheral tissues, increase gluconeogenesis in the liver and provide the substrate required for gluconeogenesis. Glucocorticoids also slow down the oxidative catabolic process of glucose.

2.2 Increase glycogen content: Glucocorticoids can promote the synthesis of hepatic glycogen and increase the content of hepatic and muscle glycogen.

Side effects: Steroidal diabetes mellitus can occur if glucocorticoids are overdosed.

3. Fat

Glucocorticoids promote the breakdown of fat and increase the amount of free fatty acids in the blood. Glucocorticoids also stimulate insulin secretion by elevating blood glucose followed by fat synthesis, increasing the amount of fat in the body.

Side effects: Excessive glucocorticoids can alter the distribution of fat in the body, creating a full moon face and centripetal obesity. This is because the breakdown of fat occurs first in the trunk extremities and the accumulation of fat is concentrated in the trunk area.

4. Water and electrolytes

Glucocorticoids and promote sodium absorption and potassium, calcium and phosphorus excretion.

Side effects: Too much glucocorticoid can lead to sodium retention and potassium loss. Because glucocorticoids promote protein breakdown, they also cause potassium to drain from the cell to the outside.

How can I reduce the side effects associated with glucocorticoids?

Glucocorticosteroids have side effects that are more pronounced when used in large amounts over a long period of time.

1. When glucocorticosteroids have to be used, the appropriate glucocorticosteroids should be selected according to the condition of the disease, and short-acting glucocorticosteroids are preferred.

2. The medication is administered according to the physiological pattern of a person's own glucocorticoid secretion, e.g. around 8 a.m. in the early morning is the best time to give the medication.

3. Low-salt, low-sugar, high-protein diet, with potassium chloride and vitamin D supplements if necessary.

4. Symptomatic treatment if other symptoms are present.

5. In addition, withdrawal should be slow and not abrupt when used for a long period of time.

Hand typing is not easy, please move your fingers , click to follow.

Any questions about medication, please leave a comment or private message and be sure to respond!

The above is for reference only and is not to be used as a basis for medication or diagnosis, please consult a regular hospital for details!

　　1、Body fat

　　Because too much hormone will make people redistribute fat, people's limbs start to become less fat, face, upper body fat increases, the phenomenon of "full-moon face, buffalo back", but after stopping the drug it can be restored. In addition to fat, prolonged use of hormones may result in acne, high body hair, thinning of the skin, and so on.

　　2. Cardiovascular disease

　　Prolonged use of hormones can slowly increase water and sodium retention, blood lipids, etc., which may eventually lead to the development of hypertension and atherosclerosis, and in severe cases, other cardiovascular diseases, such as heart-related conditions.

　　3. Suppression of immunity

　　There is a possibility of exacerbation, mainly due to the hormones lowering the body's immunity, infecting the body with certain germs, or stimulating certain secretions in the body, leading to exacerbation or triggering of diseases, such as gastric ulcers, fever, and so on.

　　4. Metabolism-related diseases

　　This one will mainly have symptoms such as osteoporosis, necrosis of the femoral head, and wounds that are hard to heal, which is the result of hormones disrupting various metabolisms in the body for a long time.

Hormones are called hormones, divided into several categories, on the meaning of what you ask, should refer to the glucocorticoid, that is, this is the pine that pine of this class of drugs, but also the common people usually say hormones, it is divided into medium-acting, short-acting, long-acting, internal and external intravenous and inhalation of several kinds of drug delivery, in principle, the choice of what the hormone, how long to use, the need for doctors to grasp a good balance between therapeutic efficacy and side effects, it's a technical work! It is also a work of art, but also need the cooperation of the patient, neither can reject it, nor can not be used indiscriminately, under the correct guidance of experienced doctors can still be used without fear!

As for the side effects, we have a jargon, called 'full moon face, buffalo back' is one of them, the main side effects are 1, osteoporosis: long-term use of large doses will lead to! Even femoral head necrosis long-term use should pay attention to calcium supplementation!2, gastric mucosal damage:Increase gastric juice and pepsin secretion, causing gastroduodenal ulcers! When using the best with gastric drugs! Such as omeprazole, pantoprazole, etc.! 3, centripetal obesity: big belly, full moon face, buffalo back! 4, elevated blood sugar, electrolyte disorders! Use to monitor blood sugar, especially diabetics! 5, mental excitement, increased diet, insomnia, etc.! 6 induced infection! Although he can stimulate hematopoiesis, but can be inhibited to reduce the function of white blood cells, but also immunosuppression commonly used drugs!

In short, we have to look at hormones correctly, use them rationally, reduce them gradually, pay attention to the prevention of side effects and protection, or a very good drug!

Hormone is a term that is often on the lips of the common people. Since a number of products in the farming, planting, cosmetic, food and other industries have some relationship with hormone use and often lead to undesirable health problems, the common people are now in the state of talking about hormones.

First of all, there are many types of hormones. The main ones that are common in our lives and commonly used in clinical medicine are glucocorticoids and female endocrine-related hormones.

In previous articles and Q&A sessions, Mr. Han has talked about the effects and side effects of female endocrine-related hormones. In fact, the most obvious side effects of female-related hormones are that estrogen can easily lead to hypercoagulability or even thrombosis; of course, estrogen and progesterone may potentially stimulate and cause recurrence of breast and cervical cancers, so women with a history of thrombosis, family history, and any malignant tumors or suspected tumors should avoid using them. Progesterone has a major effect on the body's sugar, lipid and amino acid metabolism. There are also medications that cause menstruation to stop, and they may cause side effects such as osteoporosis and menopause-like symptoms in women.

When it comes to glucocorticosteroids, we are most concerned about the problem of gaining weight, because the use of these drugs will lead to a greater change in fat metabolism in the body, fat redistribution, which is often referred to as centripetal obesity, the typical symptoms of a full-moon face, buffalo back, and a tiger's back and waist. In addition, the side effects of glucocorticoids include increased blood pressure, elevated blood sugar, peptic ulcers, edema, and even gastrointestinal bleeding and osteoporosis. Some patients may also suffer from decreased immunity, susceptibility to infection, and mental abnormalities (e.g., euphoric state, easy insomnia, personality changes, etc.).

Glucocorticosteroids can play an anti-inflammatory, inhibit immune response, reduce capillary permeability and other effects, very suitable for the treatment of allergic skin diseases, inflammatory skin diseases, but once discontinued, the skin problems will break out rapidly in a short period of time, resulting in large areas of erythema, itching, skin burning and other serious skin problems. If long-term use of hormones may also disrupt the normal functioning of the body, causingFat accumulation, facial acne, osteoporosis, high blood pressureand other side effects.