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Is prednisone a glucocorticoid?

Is prednisone a glucocorticoid?

First of all, thank you for your question. Here is a brief introduction to prednisone.

Prednisone is actually prednisone acetate, also called dehydrocortisone. It is an adrenocorticotropic hormone or called a glucocorticoid, and its a medium-acting glucocorticoid. It is secreted by the adrenal cortex and regulated by the hypothalamus-anterior pituitary-adrenocortical axis. It has anti-inflammatory and anti-allergic effects, and can inhibit the proliferation of connective tissue. Quacks usually add this product for use in order to accelerate the anti-inflammatory effect. However, long-term use can cause centripetal obesity, hirsutism, full moon face, acne, swelling, hypokalemia, diabetes mellitus, and induced and aggravated ulcers. According to the duration of action, glucocorticoid drugs can be categorized into short-acting, medium-acting and long-acting. Short-acting drugs such as hydrocortisone have an action time of 8-12 hours, medium-acting drugs such as prednisone and methylprednisolone have an action time of 2-36 hours, and long-acting drugs such as dexamethasone and betamethasone have an action time of 36-54 hours. Glucocorticoid is an extremely important class of regulatory molecules in the body, which plays an important role in regulating the development, growth, metabolism and immune function of the body, and is the most important regulatory hormone for the body's stress response, and is also the most widely used and effective anti-inflammatory and immunosuppressive agent in the clinic. Glucocorticoids are often the first choice of treatment in many particularly urgent or critical situations.

I hope the above answers help you a little.

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Prednisone, also clinically called prednisone, is one of the more commonly used glucocorticosteroids.

Glucocorticosteroids such as prednisone have a wide range of uses and can be used in the treatment of a variety of diseases, which has led to the emergence of but hormone abuse. Below, Xiao Ke will introduce the formal clinical application of glucocorticoids:

1. Severe bacterial and viral infections: mainly used for patients with toxic infections or shock, it can rapidly relieve the symptoms of toxemia, thus protecting the important organ function, glucocorticosteroids do not have any antibacterial effect, but also reduce the body's resistance, so when used for severe bacterial infections, it is necessary to be applied in sufficient quantities and effectively.

For patients with viral infections, hormonal drugs are not recommended for milder viral infections, such as zoster virus and chicken pox virus. But for severe hepatitis, mumps, measles and encephalitis B, in order to be able to quickly control the symptoms, you can use the way of surprise therapy to prevent complications, and when the efficacy of the drug is obtained, it should be withdrawn in time.

2. Anti-inflammatory treatment and certain inflammatory sequelae: when inflammation is gradually recovered in the later stages of the process, the formation of scarring and adhesions will seriously affect the function of the corresponding organs, so the early use of hormones can reduce the exudation of inflammatory substances, reduce adhesions and prevent the occurrence of sequelae.

3. Autoimmune diseases: hormones can be used to relieve rheumatic fever, rheumatic myocarditis, rheumatoid arthritis, systemic lupus erythematosus and other diseases, but they should not be used alone, and should be used in combination therapy.

4. Shock: It is mainly used as an adjunctive treatment for infectious toxic shock, and is used on the basis of adequate and effective antimicrobials, which help to relieve microcirculatory disturbances and control shock.

These are the views of Xiao Ke, welcome your questions and additions, pay attention to Xiao Ke, to learn more about health knowledge.

is. Glucocorticoids are a class of steroid hormones secreted by the body from the adrenal cortex fasciculus, of which prednisone is one.

  • In physiological doses: it regulates the biosynthesis and metabolism of the body's three major nutrients, sugars fats and proteins;

  • In pharmacological doses: it has a very powerful and wide range of pharmacological effects, such as anti-inflammatory and anti-allergic as well as immunosuppressive effects;

In view of the powerful pharmacological effects of prednisone, if not used properly may bring about many adverse reactions, so there are restrictions in the use of dosage are clearly regulated. Prednisone is generally used in the treatment of rheumatologic and immunologic diseases and allergic diseases.

  • It is commonly used in the management of acute exacerbations in rheumatologic diseases for acute anti-inflammation, among other things.However, all need to be tapered off and then discontinued after remission;

  • Another common use is for the treatment of allergic diseases, usually in the form of a topical cream for allergic skin disorders, and itchy skin.

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