Why is chuanxiong rhizome called the "blood neutralizer"? What is the pharmacology involved?
Hello, I am glad to answer your question. Chuanxiong is also known as "Rhizoma Ligusticum", "Rhizoma Ligusticum" or "Rhizoma Ligusticum". It has been recognized as a "blood qi medicine" by medical writers throughout the ages, such as the Qing Dynasty medical work "Medicine Cage", which says, "Chuanxiong is a blood qi medicine that rises the yang and opens up the depression, moves up to the head and eyes, and moves down to the sea of blood". Many people can not figure out what the specific meaning of the blood in the gas medicine, the next, Dr. Zhu combined with the theoretical knowledge of traditional Chinese medicine, for you to do a comprehensive pharmacological principles of the answer to analyze.

Rhizoma Chuanxiong has a long history of use in medicine and its own distinctive characteristics. The Divine Husbandman's Classic of the Materia Medica, written in the Han Dynasty, says that Chuanxiong is pungent and slightly warm, and that it can be used to treat "strokes into the brain". Please note that the stroke it refers to is not a cerebral vascular accident, but rather an exogenous disease in which the human body is exposed to wind. Chuanxiong is also said to be the mainstay of "cold paralysis, contracture of tendons and slow urgency". Cold paralysis means stagnation of blood vessels due to cold and dampness obstructing the meridians, resulting in contracture of tendons and bones and pain. The so-called main cold paralysis is Chuanxiong can penetrate into the blood, pass up and down the body of the qi and blood. Among the internal organs, the liver stores blood and regulates the volume of blood in the veins, and Chuanxiong works on the liver. The head is the confluence of the three yang meridians of the hands and feet, Chuanxiong can pass through the meridians on the surface of the body to dissipate the wind and cold, so it can be seen that Chuanxiong has both the surface and the inside of the body, the qi and blood with the same reach, which is a high degree of "blood in the qi medicine" in a nutshell.

The role of chuanxiong as a blood-mediated qi medicine can be traced back to the Han Dynasty. In the Treatise on Typhoid Fever, it is believed that Chuanxiong can regulate the liver and open up depression, as the liver is responsible for draining qi, and if liver qi is not flowing well, qi and blood are bound to be stagnant. An example of this is the compounding of Si-Bei San (四逆散). In the Tang Dynasty, Sun Simiao believed that Chuanxiong could remove "wind from the head and face", indicating that Chuanxiong could dispel wind and relieve pain, and act on the surface of the body and head to dispel wind. After summarizing the experience of his predecessors, Chen Jiamu, a Ming Dynasty pharmacist, first proposed that Chuanxiong "passes through the liver meridian, and is also a medicine for qi in the blood". The specific embodiment of Chuanxiong should be combined with the principle of action and the characteristics of the medicinal properties of Chuanxiong. It is analyzed as follows:

★The principle of action of Chuanxiong, a blood and chi agent
- Chuanxiong is the rhizome of a plant in the Umbelliferae family, and plants in this family all maintain a fresh scent (e.g., Angelica dahurica, ligustrum). Currently, it is mainly produced in the regions of Sichuan, Hubei and Yunnan. Long ago, Chuanxiong was often called "Ligusticum", because the best quality of Chuanxiong produced in Sichuan, with high content of volatile oils, special flavor and good therapeutic efficacy, was regarded as a "local medicinal herb", and was therefore called "Chuanxiong Chuanxiong". The principle of action is as follows:
Ligusticum Chuanxiong, from Chuanzhong. Large pieces, white in color, not oily, slightly pungent and sweet when chewed are good - Derivation of the Essential Materia Medica (本草衍义).
- The ancient Chinese character for rhizoma lovage means "sky", which in combination with the human body means that it acts on the highest part of the head. Chuanxiong has a clear, fragrant odor, and the odor is greater than the taste, and qi is yang. The Four Sacred Sources of the Heart" said that "clear is floating up, turbid is sinking down," the fragrance of the drug has the characteristics of ascending, floating, dispersing and running through the characteristics of the Rhizoma Ligustici Chuanxiong smells fragrant and strong, can be upward in the head and face, and outside the surface of the body, dispersal characteristics can be dispersed out of the wind in order to alleviate the pain, the head and face is the highest place in the human body, is the hands and feet of the three yang meridians convergence of the part, also known as the "meeting of all yang". The head and face are the highest part of the human body and the meeting place of the three Yang meridians of the hands and feet, also known as the "meeting of the Yangs". Among the six evils, wind is the only one that is good at running away and ascending, and it is easy to attack the head and face. Rhizoma Chuanxiong can directly dissipate the wind evil through dispersal. The wind evil originates from exogenous infection or liver qi stagnation, and the liver qi is over-dispersed.
Feng Qi leads to the Liver - Yellow Emperor's Classic of Internal Medicine

- The odor of Chuanxiong can regulate liver qi, because the liver likes to regulate and hates depression, liver qi is the basis for the rise of yang qi in the human body, due to emotional upset, dietary disorders and other factors often lead to liver qi stagnation, liver qi stagnation qi stagnation, not through the pain, headache, body pain, pain in the limbs often occur. At the same time, qi stagnation is prone to blood stasis, and the two affect each other. At this point, the need for dispersing and dispersing drugs, Chuanxiong can open the depression to move qi, dredge qi and blood, which is partly the basis of Chuanxiong's action to dispel wind, relieve pain, move qi, but also its blood in the blood of qi medicine "qi medicine embodiment".
Adding chuanxiong to this medicine moves qi and regulates blood and stops the pain - Ben Jing Feng Yuan

- Chuanxiong, with its pungent flavor, is said to be "pungent in dispersing" in the Jinjian of the Medical School. It is meant to disperse superficial evils. The outer skin is black and red, the inner color is white, and the texture is heavy. The red color can enter the blood vessels, and with its characteristic of running away, it can be used to stagnate the blood vessels.The odor and fragrance can be ascending in the upper part of the body, the texture is heavy and feasible in the lower part of the body, theIn the Materia Medica, it is said that Chuanxiong can "move up to the head and eyes, and down to the sea of blood". The sea of blood refers to the uterus in women, and in Chinese medicine, the Chongqin (冲脉) is considered to be the sea of blood, and it works together with the liver to regulate menstruation, pregnancy, childbirth and breastfeeding in women, and is called the sea of blood as it starts from the uterus. Rhizoma Chuanxiong is often used in female medicine for its role in regulating the flow of blood and qi.
- The properties of Rhizoma Ligusticum Chuanxiong can be summarized as: pungent and warm in nature, invigorating the blood and promoting circulation of Qi, dispelling wind and relieving pain.

Summary of Chinese Medicine Theory of ★Blood and Chinese Qi Medicine
- According to Chinese medicine, qi is the commander of blood, and blood is the mother of qi, and qi and blood are interdependent and mutually dependent. Rhizoma Chuanxiong dispels wind and eliminates surface winds by dispersing them on the surface of the body and the head, the surface belongs to yang, and yang belongs to qi, so Rhizoma Chuanxiong can be called a "qi medicine". Chuanxiong smell fragrant, good at running, can penetrate into the liver meridian blood, pass blood stagnation, liver blood, belongs to the internal organs, this is the embodiment of Chuanxiong "blood medicine". From a comprehensive point of view, no matter whether it is caused by external wind evils or internal injuries and emotional disorders that lead to liver qi stagnation and wind problems, Chuanxiong can be combined with them, because the main part of the action is the liver, the liver stores blood, and can pass through the whole body up and down and inside and outside, and has the effect of moving qi, so it is known as the qi medicine of the blood.
Rhizoma Chuanxiong is a qi medicine in the blood. Helps clear the yang and open all the depression, (Danxi said: if the qi rises, the depression comes down, as the ambassador of yin and yang, blood and qi) -- "Materia Medica Prepara".

★ Chuanxiong is widely used in clinical practice, note that the pungent and aromatic properties of Chuanxiong tend to consume fluids and stimulate fire, so it is not suitable to use Chuanxiong for headaches where the liver is on fire. Dr. Zhu has encountered headaches and increased blood pressure after taking Chuanxiong for people with hyperactivity of the liver yang and liver fire and needs to pay attention to this aspect of the problem, although the drug should also be used in accordance with the evidence and abuse of the drug is likely to cause adverse reactions.
Lastly, I hope my answer was helpful.
Note: In the text, reference is made to theoretical works on Chinese herbal medicine, combined with personal experience and opinions, and the images are from the Internet.
Ligusticum chuanxiong: The herb has been included in all generations of materia medica.
Pungent and warm in nature. Attributed to the liver, gallbladder and pericardium meridians.
Effects Promoting blood circulation and circulation of Qi, dispelling wind and relieving pain. It can be ascending and descending, and has the effect of promoting blood circulation, moving qi and relieving pain.
Element Chang described Chuanxiong: it goes up to the head and eyes, and down to the sea of blood.
The Compendium of Materia Medica is said to be: blood in the gas medicine.
Because of this, it is clinically used for all kinds of pain caused by stasis of blood or blood stasis and qi stagnation.
Rhizoma Ligustici Chuanxiong belongs to the Liver meridian of the foot syncopal meridian, and should be used for headaches.
Modern pharmacological studies have proved that Chuanxiongzine is its main active ingredient.
The pathways of action of chuanxiongzine in the organism and the localization and distribution in cells, tissues, and organs are correlated with the chuanxiong repertoire.
Chuanxiongzine acts primarily in the liver and can cross the blood-brain barrier into the brain, closely related to chuanxiong for headaches.
Pharmacological effects of Chuanxiongzine: It has the effect of dilating small arteries, improving microcirculation, increasing cerebral blood flow and activating blood circulation and removing blood stasis. It also has the effect of anti-platelet aggregation.
Chuanxiongxizine is mainly used for occlusive vascular disease, cerebral thrombosis, vasculitis, coronary heart disease, angina pectoris. It is effective in the acute and recovery stages of ischemic cerebrovascular disease and its sequelae, such as insufficient cerebral blood supply, cerebral thrombosis, cerebral embolism and cerebral arteriosclerosis.

Rhizoma Chuanxiong has the efficacy of activating blood circulation, moving qi, dispelling wind and relieving pain. It is pungent, dispersing, warming and promoting, which can both invigorate blood circulation and remove blood stasis, as well as move qi and relieve pain, so it is known as a qi medicine in the blood, which can promote the circulation of qi and blood. Its blood-activating function is mainly reflected in the protective effect of the active ingredient Chuanxiongxizine on the cardiovascular and cerebral vascular system, for example, it can protect cardiomyocytes, diastole vascular smooth muscle, improve cerebral ischemia, and improve blood rheology. The diastole of vascular smooth muscle can be used as the basis for the pharmacological action of activating blood and moving qi at the same time.
Rhizoma Ligustici Chuanxiong is a commonly used blood-activating herb with a pungent and warm flavor that belongs to the liver, pericardium, and gallbladder meridians, and its main effects are to activate the blood circulation and promote circulation of qi, and to dispel wind and relieve pain. Rhizoma Chuanxiong moves upward to the head and eyes, dispels wind and prevents dampness, and is good at treating migraine with wind-cold, such as Qiangwu Shengxu Tang, which is used to treat wind-dampness on the surface, headache, and lumbar and spinal pain; Rhizoma Chuanxiong passes through the channels of qi and blood, and is good at treating menstrual disorders, dysmenorrhea, amenorrhea, postpartum stasis of blood and abdominal pain, and pain from trauma, which is caused by blood stasis, and has a very wide range of gynecological applications. Chuanxiong is good for treating wind-cold paralysis, e.g. Duhu Shengsheng Tang is used to treat numbness of limbs, relieve pain, and limb flexion and extension; Chuanxiong regulates qi and relieves pain, and is good for treating chest and hypochondrium pain due to liver stagnation and stagnation of qi, e.g. Chaihu Shuohe San is used for treating hypochondrium pain with chills and fever. It is often combined with Angelica sinensis to regulate menstruation and relieve pain, with Angelica dahurica to dispel wind and cold and relieve pain, and with Chai Hu to relieve liver stagnation and promote circulation of Qi.
Chuanxiong has a thin flavor and strong qi, and is the most liberal in nature, capable of ascending and dispersing, going up to the top, reaching the limbs, and going down to the sea of blood, walking without guarding, although it is an important medicine for gynecology to regulate the blood, it should not be abused by those who have a deficiency of blood, and if it is not used appropriately, it will lead to depletion of qi and injury to the yin. The use of Chuanxiong in the Four Substance Soup is not to tonify blood, but to take its pungent fragrance to disperse, so that the tonic can be passed, without the disadvantage of stagnation.
Chuanxiong is good at moving and dispersing blood, has the effect of promoting blood circulation and eliminating blood stasis. Although it is a blood-activating medicine, it has the obvious effect of promoting qi, can promote qi, promote blood circulation without stagnation, and can play the role of promoting blood circulation and regeneration of new blood in blood-supplementing formula. The most important characteristic of Chuanxiong is that it is capable of promoting the circulation of Qi and Blood, and secondly, it is of the nature of running away, promoting the circulation of Blood without leaving stagnation. Chuanxiong line blood in the qi, can not only activate the blood to eliminate blood stasis, but also can move qi stagnation, so the "Materia Medica Hui Yan" said: "Ligusticum, up the head and eyes, down to regulate the menstrual flow, in the middle of the opening of the depression, the blood in the qi medicine."
Rhizoma Chuanxiong is pungent, warm, ascending and dispersing, and should be used with caution in cases of yin deficiency and fire exuberance, laborious heat and excessive sweating, excessive menstruation, and hemorrhagic disorders.
Rhizoma Chuanxiong can move qi, activate blood and relieve pain, it emphasizes on activating blood, because of its action of moving qi, so Rhizoma Chuanxiong can also promote the operation of qi, so it is said to be a qi medicine in blood!
Rhizoma Ligustici Chuanxiong, upwardly moving the head and eyes, downwardly regulating menstrual flow, centrally opening up depressions and knots, and a qi medicine in the blood. This product is warm, clear in flavor and strong in qi, and can open up the depression, move qi and blood, dredge the liver and relieve dystocia. This product is pungent and warm to go away, go and do not guard, upward head and eyes, beside the skin, can disperse cold and dampness, dispel wind, relieve head wind, treatment of eye diseases. This product belongs to the liver and enters the blood, the nature of the most unobstructed, good blood in the stagnant gas, through the twelve meridians, can break the stasis, blood, regulating menstrual water, dissipate the knot gas, eliminate stasis and swelling, and relieve pain. The flavor of pungent yang, the gas is good to run without the disadvantages of yin condensation and stagnation, although into the blood, and can go to all the wind, regulating all the gas. With Su Ye, can disperse wind and cold in the surface, with astragalus, atractylodes, can warm the middle qi and pass the liver and spleen, with Angelica sinensis, white peony, can be born blood and through the camp yin. In conclusion, Rhizoma Ligustici Chuanxiong has the functions of activating blood circulation, relieving pain, searching for wind and dampness, promoting circulation of qi and opening up depression. For gynecology, injuries, blood stasis pain in the essential drugs. It is often used for headache, irregular menstruation, dysmenorrhea, menstrual closure, and can be used for depression, dystocia, paralysis, postpartum abdominal pain, traumatic pain and other conditions.
Chuanxiong, Salvia divinorum tablets, Angelica dahurica, I take it almost every day.
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