Before answering this question, let's look at one such thing in life. Car friends must know, in the trunk of the car has a spare tire, in case of urgent need to come in handy, perhaps this spare tire in your driving process for more than ten years are not used, but with the increase in the age of the car, this spare tire is also undergoing aging, with the car's scrapping, it will be the end of the life of the car.

In fact, human blood vessels are the same, even without any disease, it will also be aging, atherosclerosis, and medical research has confirmed that people from the age of 10 years old began to occur atherosclerosis, but the rate of occurrence is extremely slow, so some people say that the blood vessels of the life that is the life expectancy of the person, which is justified.

And once a person develops atherosclerosis as a result of a disease, it indicates that there is something wrong with the body, and the purpose of treatment is not to reverse atherosclerosis, but to stop its rapid progression, as evidenced by the mechanism of atherosclerosis occurring as a result of the disease.Pathological atherosclerosis, is due to high blood sugar, high blood pressure and other damage to the endothelium of the blood vessels, lipids in the blood, especially low-density lipoproteins deposited in these small parts of the damage, and make the blood vessel wall thickening, brittleness and elasticity increased, if a certain part of the deposition of lipids is too much, the formation of plaques, these deposits and plaques are like in the blood vessel wall roots, it is difficult to uproot the roots.

Some people may say, "I don't have high blood pressure or diabetes, the endothelium of blood vessels will not be injured, so pathological atherosclerosis should not occur, right? In fact, there are many possible causes of endothelial damage, such as emotional stress, smoking, inflammation, etc., which will inevitably cause endothelial damage.Moreover, with age, all kinds of metabolic functions are declining, causing atherosclerosis to occur in the LDL level is rising, especially with diabetes, high blood pressure, this situation occurs more obvious. That's why you need to take lipid-lowering drugs to bring down LDL, and you need to take them for life.

It can be seen that the treatment of atherosclerosis by taking medication merely lowers the level of LDL and does not change the mechanism by which atherosclerosis occurs, so it cannot reverse the atherosclerosis that has already occurred, but it does greatly reduce the rate at which atherosclerosis occurs, and this is where we get the greatest benefit.

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As the living standard of the people has been greatly improved, the lifestyle has also undergone a great change, going out in the car, going home either sitting or lying down, and this change in lifestyle has also brought about a great change in the spectrum of diseases. Take cardiology as an example, the disease spectrum from the 1960s and 1970s, mainly rheumatic heart disease, to the twenty-first century, mainly atherosclerotic disease.

The spectrum of disease has changed, and so have people's concerns about disease. At this stage, most patients with atherosclerosis ask, "Dr. Zhang, can the atherosclerosis in my body be reversed or disappear?" The more people ask, the more Dr. Zhang realized that this is a problem, today to give you a popularization.

On the question of whether atherosclerosis can be reversed, Dr. Zhang can first give an affirmative answer that the atherosclerosis that already exists in the body can be reversed in some patients due to the strict improvement of lifestyle and the regular use of lipid-lowering drugs, such as statins. This reversal can be manifested as a reduction in plaque size, as well as the disappearance of plaque.

At this stage, there is an academic basis for two statins, Rosuvastatin and Atorvastatin, regarding the drugs that can achieve plaque reversal, and it is likely that more lipid-lowering drugs will be available in the future as they continue to become available.

However, Dr. Zhang would like to conclude by saying to the majority of patients with cardiovascular and cerebrovascular diseases or atherosclerotic diseases, don't hope that the body will realize plaque reversal through oral medication after finding atherosclerotic plaques. In fact, a more realistic idea is to live a healthy lifestyle so that plaque does not occur or even if atherosclerotic plaque occurs, regular medication and improve lifestyle, so that the atherosclerotic plaque does not further increase, which is the majority of cases can be realized, after all, atherosclerotic plaque reversal is very difficult.

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I really want to take a stick and poke out the garbage inside the blood vessels. So many of my friends with narrowed blood vessels and atherosclerosis formation have thought of this in one way or another.

On the left are the blood vessels when we were first born, and on the right are the atherosclerotic vessels.

How do you reverse it? Only by traveling! Travel back in time to reverse it!

Isn't it possible to reverse this with medication? If it can't why do people take pills all day long.

The vast majority of atherosclerosis is irreversible, but that's not to say we can ignore it.

We slowly develop atherosclerosis from our teenage years, and if we have bad lifestyle habits, we will develop atherosclerosis, and the causes that aggravate atherosclerosis include: genetic predisposition, age and gender; this is unchangeable.

But most bad habits aggravate atherosclerosis: smoking, hypertension, diabetes, hyperlipidemia, obesity, metabolic syndrome, inactivity, depression, renal insufficiency, and so on.

We can only change these bad habits to delay atherosclerosis and reduce the occurrence of cardiovascular diseases.

The predominant drug currently used against atherosclerosis formation is the statin drug, which is anti-inflammatory, stabilizes plaque and prevents plaque rupture.

A simple understanding of the current theory is that atherosclerosis formation is an inflammatory response, and statins have the ability to combat this inflammatory response.

However, statin is difficult to eliminate for most plaques, and the best outcome for plaques that have formed is to remain stable and not get worse.

Therefore, it is difficult to eliminate atherosclerosis by taking medication; it can only delay and stabilize plaque.

We should not wait until atherosclerosis aggravates to cause serious stenosis to pay attention to atherosclerosis, but to develop from childhood: quit smoking and alcohol, exercise, low-salt, low-fat and low-sugar diet, early detection and early treatment of the three highs, regular work and rest, and happy good habits, to prevent the aggravation of atherosclerosis!

I. Atherosclerosis is a natural law of life, age and death

The so-called atherosclerosis is a process in which lipids are deposited in the endothelium of the arterial blood vessels and accumulate over time, and it is also a chronic disease, a gradual process of gradual formation and aggravation! Atherosclerosis is the natural law of human birth, ageing, sickness and death, and also from birth to death, atherosclerosis through the whole life from birth to death! Therefore, atherosclerosis is present from birth and is as irresistible as ageing!

Second, how is atherosclerosis treated?

The main drugs in the treatment of atherosclerosis are lipid-regulating and plaque-stabilizing statins, whose main mechanism of action is to reduce cholesterol and LDL, since cholesterol and LDL are the main pathogenic causes of atherosclerosis! Reducing both slows down their pathogenesis! And it can make already existing plaques stable, hardened and less likely to rupture and thus lead to acute events!

Third, is reversal of plaque likely to occur?

In studies of lipid-lowering drugs, such as those of Codine, it is claimed that it has been reported to reverse plaque, but all that has been reported is that it has resulted in a reduction in plaque load, and no plaque has ever been seen to disappear! So, personally, I think the supposed reversal of plaque is just a gimmick! All that statin can do is to stabilize the plaque as much as possible and slow down the process of plaque development, as for reversal, or it may occur in the future, but at least it needs to wait and take time!

We look forward to the day when plaque can be reversed ......

I was once asked a similar question by a patient, but he asked notatherosclerosisCan it be reversed, but rather the question ofhardening of the arteriesCan it be reversed? Seeing this you may be a little confused, aren't they the same thing? Of course not, they are two completely different concepts, and that's why people are questioning -Some doctors say it can be reversed, while others say it can't be reversed cause; it's not really that we're wrong, but it's just that people aren't talking about the same issue at all, and that's embarrassing!

Atherosclerosis is a systemic disease, which can involve all arterial vessels in all parts of the body, it is caused by non-inflammatory lesions of the blood vessel wall thickening, hardening, decreased elasticity, which ultimately leads to the narrowing of the lumen of the arterial vessels; this kind of atherosclerosis is with the growth of age and the gradual emergence of factors that lead to the occurrence of its controllable and uncontrollable two kinds of factors, such as smoking, drinking alcohol, hypertension, high blood pressure, high blood lipids, High blood sugar, lack of exercise, improper diet, etc. are controllable factors, while age, heredity, gender are non-controllable factors;

Atherosclerosis continues to occur in the presence of uncontrollable factors, and controllable factors are the add-ons that cause this hardening to worsen, in other words, even if all controllable factors are excluded, atherosclerosis still occurs, which is difficult to stop and irreversible; after all, no one can turn back time!

Atherosclerosis is a disorder of lipid metabolism as the basic etiology, mainly involving large arteries and medium arteries, its mechanism is as follows: when the endothelial structure of the arteries is damaged for some reason, lipids in the blood will be leached into the endothelium through the damage, and a large amount of lipids will accumulate under the endothelium, forming a mass of atheromatous structure with a yellow color, which is known as atherosclerosis; during this process, more and more lipids are deposited in the damaged endothelium. During this process, more and more lipids are deposited in the damaged area of the arterial intima, and localized accumulation of lipids and complex sugars, fibrous tissue proliferation, and calcium deposits slowly form protrusions toward the interior of the blood vessel, which are what we call arterial plaques;

This atherosclerotic plaque can be reduced or even disappear under the action of drugs, that is to say, drugs can reverse atherosclerotic lesions, but at present there are not many drugs that can achieve this effect, and there is only two kinds of drugs confirmed by evidence, namely, Rosuvastatin and Atorvastatin!

In summary, we can learn that atherosclerosis is difficult to reverse, but atherosclerotic plaque can be reversed!

The above is for reference only, and corrections are welcome!

Ask this question friends, not only want to take medicine to atherosclerosis complete recovery, but also want to completely cure, so as to achieve the effect of stopping the drug, but the ideal is very plump, the reality is very cruel, atherosclerosis of the occurrence of the development of the hard, it is very difficult to do a complete reversal of the development of the atherosclerosis, if there is really such a drug, then the person's rejuvenation, immortality can be realized.

There is no doubt that our current level of life science, medical technology, is not up to the level of completely reversing atherosclerosis.

With age, our body will gradually aging, and the arteries can not be an exception, even if there is no three high and slow disease and other factors, with the gradual aging of the human body, the aging of the arteries, hardening is inevitable, therefore, atherosclerosis, although it is the basis of cardiovascular and cerebral vascular disease problems, and many chronic diseases, the impact of bad habits are closely related to the age of the same can not be ignored in one aspect, the age can not be reversed. Age can not be reversed, atherosclerosis can not be completely reversed.

Atherosclerosis is not always a serious problem

Atherosclerosis is an important risk factor for cardiovascular and cerebrovascular diseases, but the presence of atherosclerosis in the arteries does not necessarily mean that cardiovascular and cerebrovascular diseases will be triggered. In fact, with age, the vast majority of people more or less will have some atherosclerosis, aging problems, but whether atherosclerosis will affect the cardiovascular and cerebrovascular as well as other aspects of the body's health, mainly depends on the severity of the atherosclerosis, resulting in the degree of narrowing of the arterial vessels, as well as the stability of the arterial plaques and other aspects.

Therefore, atherosclerosis as a disease problem, rather as a gradual change of the body, and this problem if we actively pay attention to, strict control, can slow down the development of it, reduce the atherosclerosis brought about by cardiovascular and cerebral vascular health risks, and if we do not control the related risk factors, allowing atherosclerosis to develop further, triggered by related diseases risk will be greatly increased. Therefore, we must look at the problem of atherosclerosis from a developmental perspective. Although it is not possible to completely reverse atherosclerosis, it is possible to strengthen the control of atherosclerosis and reduce the health risks it brings.

Can taking medication reverse atherosclerosis problems?

Although the impossibility of complete reversal has been emphasized, it is still necessary to talk about this specific issue. By taking medication, reasonably regulating the relevant chronic disease problems, especially strictly controlling the relevant blood lipid indexes, there is indeed a certain possibility that the atherosclerotic plaques that have been produced will become relatively smaller, but it is impossible to completely disappear and allow blood vessels to completely restore health. Even if you want to make the plaque smaller, in fact, it is not easy to do, you need to LDL cholesterol levels, HDL cholesterol, the level of the relevant apolipoproteins at the same time to meet certain conditions, and to maintain a stable long-term, in order to achieve the atherosclerotic plaques to reduce the relative size of the possibility of a little bit, but in order to do these points, you often need to take a larger dose of drugs, the risk of adverse drug reactions will also be greatly increased. The risk of adverse drug reactions is also greatly increased.

So we for atherosclerosis, we do not recommend must make plaque "reversal or disappear", for atherosclerosis, we should first of all is to do a good job of prevention, understand the risk factors that lead to atherosclerosis, in time to control as early as possible; Secondly is to try to control atherosclerosis of the further development of atherosclerosis, to do a good job of atherosclerosis caused by cardiovascular disease risk control. Atherosclerosis leads to cardiovascular and cerebrovascular disease risk control, do these two things, than too hard to hear thinking about how to take medication to reverse plaque, a complete cure for atherosclerosis to, to be much more reliable.

Atherosclerosis, active prevention is most important

Although almost inevitable, we can still slow down the development of atherosclerosis through a rational and healthy lifestyle and active management of chronic diseases.

When we find that the blood pressure has a tendency to rise and has not yet reached the diagnostic standard of hypertension, we are able to actively do a good job in life conditioning intervention to keep the gradually rising blood pressure under control; when we have impaired fasting blood glucose, which has not yet risen to more than 7.1, and diagnosed diabetes mellitus, we are able to actively regulate the elevated blood glucose through diet and exercise, to further lower it; when we find that the blood lipids have increased, we are able to actively assess cardiovascular risk, and reasonably set the goal of blood lipid control through life or plus medication to actively regulate and control it to keep it at a stable and standard level. When we find elevated blood lipids, we can actively assess cardiovascular risk, reasonably set the goal of blood lipid control, and actively regulate and control it through life or with medication to keep it at a stable and standardized level. In life, if we can also do to quit smoking and limit alcohol, do not stay up late, control obesity, scientific and reasonable healthy diet, adhere to moderate exercise, such good living habits, coupled with active chronic disease management and control, will be able to greatly reduce the risk of the occurrence of atherosclerosis, atherosclerosis will be maintained at a milder level, the risk of the formation of cardiovascular and cerebral health effects will also be greatly reduced.

Pre-existing atherosclerosis, controlling progression and risk prevention is important

If you already have atherosclerosis and are at high risk of developing cardiovascular disease, all we can do is to actively control the problem, try to slow down the further development of atherosclerosis, and at the same time, pay attention to stabilizing the atherosclerotic plaque to minimize the cardiovascular risk caused by plaque rupture.

Want to do this, the first thing is to actively control the three high chronic disease problems, especially the level of blood lipids, it is recommended that as far as possible, the level of low-density lipoprotein cholesterol control to 1.8 mmol / L below, but also should pay attention to high-density lipoprotein cholesterol and triglycerides and other lipid indicators of health standards, lipids control to this value, the process of atherosclerosis will usually slow down, the risk of cardiovascular disease, will also be greatly reduced. The risk of cardiovascular and cerebrovascular diseases will also be greatly reduced. In addition to blood lipid level, blood pressure level, blood sugar level and so on should also pay attention to control, at the same time, life aspects of the conditioning intervention, but also can not be relaxed, only from a variety of aspects of the comprehensive control of atherosclerosis further development, to be able to better protect the health of blood vessels, reduce the risk of cardiovascular and cerebral.

Blood pressure, blood lipids and blood glucose are well controlled to a reasonable reach, the stability of plaque will be improved, and the risk of atherosclerotic plaque rupture will be greatly reduced. And in order to reduce the risk of thrombosis brought about by plaque rupture, it is also recommended to take antiplatelet aggregation drugs to do a good job of thrombosis prevention, which is also an important aspect of the prevention of cardiovascular and cerebrovascular risks, taking into account the specific circumstances, under the premise of assessing the risk of bleeding and controlling the risk of medication.

So, for atherosclerosis, in the end to take drugs to control, but also specific circumstances, only the serious need to control, through the life of the intervention can not be effectively improved, only need to take medication to control, and if there is atherosclerosis cardiovascular friends, usually need to take a variety of drugs to control the further development of atherosclerosis for a long period of time, and at the same time as much as possible to do a good job of cardiovascular disease! Risk prevention, complete reversal of atherosclerosis is not possible, the need to stop taking medication, but also to combine their own physical condition and drug tolerance, adverse reactions to determine the situation, do not easily stop taking medication.

Hello, I am Dr. Hui, Deputy Chief Physician of the Department of Cardiovascular Medicine at Dalian Central Hospital. Your question is particularly common because many people are trying to figure out how to take some medication or some special method to reverse atherosclerosis.

First we should understand the process of atherosclerosis formation. Normal arterial blood vessels are lined with a layer of endothelial cells, which is the barrier that protects the health of the blood vessels. However, some common risk factors for cardiovascular disease, such as high blood pressure, diabetes, smoking, obesity, etc., can disrupt the function of the endothelial cell layer, and then bad cholesterol, LDL cholesterol, will invade into the endothelium to form atherosclerotic plaques.

This process generally takes many years to progress from tiny foam cells to atherosclerotic plaques that affect blood flow in the arteries. Once formed, this plaque is progressive, but there are a number of ways in which it may be possible to play a role in controlling the progression of the plaque, and one of the most mainstream ways in which this can be done is by lowering the mainstay of blood lipids, which are statin lipid-lowering drugs.

On a theoretical level, it is possible that aggressive use of cholesterol-lowering drugs such as statins may reverse atherosclerotic plaques, and in actual clinical practice it has been observed that the chances of such reversal of plaques are relatively low. However, by controlling cholesterol, the rate of plaque progression is bound to slow down significantly.

One word of caution, however, is that after taking statin lipid-lowering drugs, including other types of lipid-lowering drugs, it is important to achieve certain target goal values based on one's status. Theoretically, the lower the level of LDL cholesterol, the slower the rate of plaque progression.

For example, in patients with coronary heart disease, LDL cholesterol should be reduced to less than 1.4 mmol per liter, and the reduction should be at least 50%.

The above suggestions are for reference only, thanks for the invitation.

Theoretically, it is possible to treat atherosclerosis, but so far there have been no cases of cure in real-life treatment.

What is atherosclerosis

Atherosclerosis is the most common of the diseases of the cardiovascular system, manifested in the arteries, is a layer of lipids deposited on the arterial wall like millet porridge, so that the arterial elasticity decreases and the lumen becomes narrower lesions.

Atherosclerosis Symptoms

There are variations in the disease appearing in different arteries:

aortic atherosclerosisAfter is no special symptoms;atherosclerosisIt often causes nocturia, persistent hypertension, and in severe cases, renal insufficiency;Atherosclerosis of the lower limbsIntermittent claudication and loss of dorsalis pedis arterial pulsation may occur if severe narrowing of the vessel lumen is caused;

patients with coronary atherosclerosisIfIf the diameter of the tube is narrowed by 75% or more, angina pectoris, myocardial infarction, arrhythmia, and even sudden death can occur;cerebral atherosclerosisIt can cause cerebral ischemia, cerebral atrophy, or cause cerebral blood vessels to rupture and bleed.

Is it certain that atherosclerosis requires lifelong medication?

The need for lifelong medication depends on the situation. At present, it can be determined that heart disease patients suffering from coronary atherosclerosis need to take medication for life, and there is also a category of patients suffering from stroke due to cerebral atherosclerosis who need to take medication for life.

The answer is yes: taking medication can reverse atherosclerosis.

With the improvement of living standard and change of dietary habits, atherosclerosis has become a common epidemic disease and one of the major causes of death in China. Drugs to lower lipids to reverse atherosclerosis is only one aspect, but the total effect is still affected by diet and various aspects. Without dietary control and lack of exercise, the effect of taking medication will still be canceled out.

Atherosclerosis is a disease that involves the endothelium of arteries ranging from large elastic (aorta) to medium-sized myoelastic (e.g., coronary arteries) in the somatic circulatory system, with scattered or fused plaques in the endothelium of the arteries, with lipids being the basic component, which are manifested as aggregates of lipid and necrotic tissue. Statins reduce plasma cholesterol by reducing endogenous cholesterol synthesis mainly through competitive inhibition of hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase activity, thus lowering low-density lipoprotein (LDL) levels, while being able to elevate high-density lipoprotein (HDL) levels. On the one hand, the synthesis of cholesterol by hepatocytes is reduced and the synthesis and release of very low-density lipoprotein (VLDL) is impeded; on the other hand, through self-regulation, compensatory increase in the number of LDL receptors on the hepatocyte membrane, activity, and increase in the affinity between LDL and receptors, so that a large amount of LDL in the plasma is uptake, and then metabolized to bile acids and excreted, which further reduces the level of LDL-cholesterol in the plasma. LDL-C, VLDL-C and cholesterol TC levels in plasma. It also inhibits cholesterol biosynthesis and interferes with lipoprotein synthesis, resulting in a decrease in plasma cholesterol TC levels, as well as lysing and migration of foam cells from plaques. Decrease in blood lipid levels, as well as lysis and migration of lipid foam cells, and reversal of atherosclerosis.

Improvement of lipid regulating treatment can make part of the atherosclerotic lesions to reduce or subside, and active prevention and treatment to prevent and control the progression of the lesions, and strive to achieve the reversal. In addition to statin lipid-lowering therapy, it must be combined with a reasonable diet and appropriate exercise in order to control blood lipid levels well and reduce the incidence of coronary heart disease and heart attack.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

You can't take medicine because it's not the right medicine, but reversing atherosclerosis is perfectly possible, but it's not medicine. Why produce atherosclerosis, the word involved here is bonding, the physical concept of bonding is electron binding, provide the blood with electrons bonding phenomenon will be reduced, that is to say, reversed, very simple reason.