There is a saying in Chinese medicine, "A woman is never far away from Four Substances Soup." This means that women are often deficient in blood, and the Four Substances Soup is a common formula that is mainly used to replenish blood.

I had already memorized the recipe song for Four Substance Soup in school and it is still catchy:

Four Substances, Angelica sinensis, Radix Paeoniae Ligustici, Rhizoma Ligustici.

This is a formula for blood clotting and stagnation.

It replenishes blood, invigorates blood and regulates menstruation.

The clinical evidence is in the variation.

Not only is this four-sentence formula song easy to understand, but it also covers all of the ingredients and effects of Four Substance Soup, including clinical additions and subtractions, making it an easy way to learn for beginners who are starting out in Chinese medicine.

Four Substances Tang is a tonic, belonging to the category of blood tonic, composed of four herbs: Angelica sinensis, Rhizoma Ligustici Chuanxiong, Radix Paeoniae Alba, and Radix Rehmanniae Praeparata, which have the ability toIt has the effect of tonifying blood and regulating menstruation, and is mainly used in the treatment of camp blood deficiency and stagnation.

Blood deficiency and stagnation mainly manifests as dizziness, palpitations and insomnia, colorless face, irregular menstruation, menstrual flow or menstrual closure, pain in the umbilicus and abdomen, or even mass in the abdomen and hard knots, light tongue, pale lips, claws and nails, fine stringy or fine astringent pulse.

Four things soup is a common formula to tonify blood and regulate menstruation, from the "immortal authorization of injuries to continue the secret formula", this prescription treatment by the camp blood deficiency, blood line is not smooth, Chong Ren damage caused by the deficiency.

So what are the health benefits of Angelica, Radix Rehmanniae Praeparata, Rhizoma Ligustici, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba in the Four Substances Tang formula? Let's analyze them one by one.

@Dr. Forest Xiangzi

I. Angelica sinensis

Angelica sinensis is a tonic and belongs to the category of blood tonic. Its medicinal properties are sweet, pungent and warm. It belongs to the liver, heart and spleen meridians.It has the effect of tonifying blood and regulating menstruation, activating blood circulation and relieving pain, and moistening the intestines and laxatives on the human body.

1. Clinical applications

Angelica sinensis can be used with blood tonic drugs for the treatment of blood deficiency; with blood circulation and blood stasis, menstruation regulating and pain relieving drugs, it can be used for blood deficiency and blood stasis, menstrual disorders, menstrual closure, menstrual pain; with menstrual warming drugs, it can be used for the treatment of abdominal pain in the form of deficiency and coldness; with blood circulation and blood pain relieving drugs, it can be used for the treatment of bruises; with honeysuckle and smallpox pollen, it can be used for the treatment of sores and ulcers, and with Qianghou, Fenghuang, etc., it can be used with Qianghou and Fenghuang to treat paralysis of wind-cold and dampness, and numbness of the limbs. It can be used with Qiangwu and Fangfeng to treat wind-cold paralysis and numbness of limbs.

Angelica sinensis tonifies blood to moisten the intestines and laxatives, and is used together with Cistanche, Ascophyllum and Cow's Knee in the treatment of constipation due to blood deficiency and intestinal dryness.

2. Attention to use

Angelica is sticky and greasy in nature, and should not be used by those who are full of dampness and have diarrhea.

2. Mature land

Radix Rehmanniae Praeparata is a tonic and belongs to the category of blood tonic. It is sweet and slightly warm in nature. It belongs to the liver and kidney meridians.It has the function of tonifying yin and nourishing blood and filling the marrow.

1. Clinical applications

In clinical practice, Radix Rehmanniae Praeparata is often used for symptoms of blood deficiency, such as blood deficiency, dizziness, palpitations, insomnia, as well as women's menstrual disorders and disintegration. It is often used in conjunction with Angelica sinensis, Paeonia lactiflora and Rhizoma ligustici Chuanxiong, as in Si Wu Tang.

Radix Rehmanniae Praeparata can also be used to treat various symptoms caused by yin deficiency of the liver and kidney, such as lumbar and knee soreness, spermatorrhea, night sweating, tinnitus, deafness and thirst. It can be used with kidney tonic to tonify the liver and kidneys and benefit the essence; it can be used with yin nourishing drugs to treat yin deficiency and tidal fever; it can be used to benefit the essence and blood and make the beard and hair black; it is often used with he shou wu (何首乌), niu knee (牛膝), and cuscuta (菟丝子), and it is also used to treat premature whitening of the beard and hair, such as Qibao Meibiqi Dan (七宝美髯丹).

2. Attention to use

Because of the sticky nature of the cooked ground, and more than the raw ground, impede digestion, where stagnant phlegm, distention and pain in the abdomen, less food and loose stools should not be taken.

@Dr. Forest Xiangzi

III. Paeonia lactiflora

White peony is a tonic, belonging to the category of blood tonic, with pungent, sour and slightly cold properties. It belongs to the liver and spleen meridians.It has the effect of nourishing blood and astringing yin, softening the liver and relieving pain, and calming liver yang.

1. Clinical applications

White peony can be used together with blood tonic and blood activating medicines to treat menstrual disorders due to deficiency of liver and blood; together with liver and qi regulating medicines, it can be used in the treatment of liver-spleen disharmony and pain in distension of the epigastrium and abdomen; together with Huanglian and Muxiang, it can be used in the treatment of abdominal pain in dysentery, such as Paeonia lactiflora Tang; and in the case of contractural pain in the limbs due to loss of nourishment for the tendons and veins in deficiency of yin and blood, it can be used together with licorice to alleviate urgency and relieve pain, such as Paeonia lactiflora and glycyrrhizae Tang.

Paeonia lactiflora nourishes blood and astringes yin, calms liver yang, and is used together with hyssop, ochre, dragon bone, and oyster in the treatment of hyperactivity of liver yang and headache and dizziness. It can be used to treat hyperactivity of liver yang, headache and vertigo.

In addition, Paeonia lactiflora can astringent yin to stop sweating, can be used for external wind-cold, Ying and Wei disharmony of bad wind and spontaneous sweating; for the treatment of yin deficiency and night sweating, can be used in conjunction with dragon bone, oyster, floating wheat and other applications.

2. Attention to use

Bai Shao should not be used in cases of Yang deficiency and coldness. It is the opposite of Li Lu.

IV. Chuanxiong

Rhizoma Ligustici Chuanxiong is a blood-activating and stasis-eliminating medicine, which belongs to the category of blood-activating and pain-relieving medicines. Its medicinal properties are pungent and warm. It belongs to the liver, gallbladder and pericardium meridians.It has the effect of activating blood circulation, dispelling wind and relieving pain.

1. Clinical applications

Rhizoma Ligustici Chuanxiong is a pungent, warming herb that can invigorate blood circulation and remove blood stasis, as well as move qi to relieve pain, and is known as the "qi medicine of the blood". It is often used clinically forBlood stasis and Qi stagnation pain syndromeIt can be used for the treatment of pains in the chest and abdomen caused by liver depression and Qi stagnation, depending on the condition of the patient.

Rhizoma Chuanxiong is a pungent, warm, ascending and dispersing rhizome that can move upward to the head and eyes, dispelling wind and relieving pain.have a headacheIt can be used in combination with other medicines for headache caused by wind-dampness, wind-cold, wind-heat, blood deficiency and blood stasis.

Chuanxiong is pungent, dispersing, warming and promoting, it can dispel wind and relieve pain, and can also treatRheumatic paralysis.It can be used in conjunction with Qiangwu, Duhuo, Fangfeng and Guizhi, such as the Duhuo Parasite Soup inside the Thousand Gold Formula.

2. Attention to use

Due to the pungent warmth and ascending and dispersing properties of Chuanxiong, it should be used with caution in cases of yin deficiency and fire exuberance, excessive sweating, hemorrhagic conditions with heatiness and no blood stasis, and in pregnant women.

V. Summary of the efficacy of Four Substance Soup

Four Substance Soup is a commonly used formula for tonifying blood and regulating menstruation. In the formula, Radix Rehmanniae Praeparata is sweet and warm, thick in flavor and moist in texture, and can enter the liver and kidney meridians, and is long in nourishing the yin and blood and tonifying the kidney and filling up the essence, which is the most important medicine for nourishing blood and the king's medicine in Four Substance Soup. Supported by white peony to nourish blood and benefit yin; chuanxiong to activate blood and promote qi, the four medicines together to play the function of tonifying blood and regulating menstruation.

The combination of Four Substances Soup is characterized by the use of ripened earth and white peony as Yin and soft blood tonic, with the pungent Angelica sinensis and Rhizoma Ligustici Chuanxiong, which are suitable for movement and static, tonifying blood without stagnating it, moving blood without injuring it, warming it without drying it, and nourishing it without being greasy, making it a good formula for tonifying blood and regulating menstruation.

Well, the above is my answer to your question, I hope to help you, have any questions you can leave a message, or pay attention to the@Dr. Forest Xiangzi , I'll reply to all of them in my free time. Thank you!

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Four Substance Tang is a well-known formula for nourishing blood, and as such, it is mainly used in the treatment of patients with blood deficiency.

Blood deficiency can be seen as dizziness, bland (or pale) face, pale lips and mouth, panic, insomnia, sleeplessness, fatigue, women's menstrual flow or menstrual closure, pale tongue, fine or thin pulse.

In the formula, the ripened rhizome is a good medicine to nourish yin and nourish blood, Angelica sinensis is pungent and warm, nourishing blood and activating blood, Paeonia lactiflora is mildly cold and is an important medicine to soften the liver and nourish liver-blood, and Ligusticum chuanxiong promotes qi and activates blood and is the qi medicine for blood, so as to make the Four Substances Soup complementary without stagnation.

Although Four Substance Soup is mainly used to nourish deficiency, it actually has some effect of activating blood circulation and removing blood stasis, which is especially suitable for the treatment of blood deficiency with blood stasis.

After taking Four Substances Soup for people with blood deficiency, it can make the qi and blood strong and energetic, with a rosy color, improved sleep, physical strength, shiny hair and normal menstruation for women.

It must be used clinically with evidence and should not be abused by those without blood deficiency.

The use of four things Tang should also be noted that this party does not have a clear effect of qi, for simple blood deficiency patients can use, if the qi and blood deficiency patients and qi drugs should be used together, such as the addition of astragalus, dongshen or combined with the four gentleman soup (dongshen, atractylodes macrocephala, poria, baked licorice), and the four gentleman with the combination of the so-called eight treasures, is the qi and blood to complement the famous formula.

In addition, patients with blood deficiency are prone to internal heat, for such people, the Four Substances Tang should also be appropriately adapted, for example, by replacing the Radix Rehmanniae Praeparatae with Radix Rehmanniae Saposhnikoviae Praeparatae to enhance the effect of nourishing yin and clearing heat. The use of Chinese herbal formulas must be flexible and changeable according to the individual's physical condition, not set in stone, so as to achieve a better therapeutic effect.

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Four Substances Soup, consists of four herbs: Angelica sinensis, Radix Rehmanniae Praeparata, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba. It is classified as a blood tonic in Chinese medicine prescription science and is one of the typical representative formulas of blood tonic.

This formula was used in the ancient medical book Xian Zhi Li Qin Ren Jian Secret Formula to treat pain caused by trauma with blood stasis, and in the Song Dynasty medical book Taiping Hui Min He Yao Guan Fang to treat many diseases of women. Now it is mainly used as a basic formula for tonifying and regulating blood.

Four Substances Soup is used to tonify and harmonize blood, and is used for Ying and Blood deficiency and stagnation. We know that Chinese medicine is concerned with Wei Qi and Ying Blood, that is, the development of the law of disease, Wei is the meaning of defense, referring to the surface of the skin, Wei Qi and Ying Blood refers to the different stages of the disease from the surface to the inside.

Four Substances Soup is indicated for diseases caused by deficiency of Ying and Blood, which is considered by Chinese medicine practitioners to be caused by the lack of blood circulation. The symptoms of deficiency and stagnation of Ying and Blood include dizziness, palpitation and insomnia, irregular menstruation, or menstrual closure, pain around the navel and abdomen, lack of radiance of the face, lips and nails, pale tongue, and thin and stringy pulse, which are also known as signs of Blood deficiency. People with these symptoms can use Four Substances Soup to tonify blood.

As we know, the combination of traditional Chinese medicine prescriptions emphasizes on the combination of ruler, minister and enabler. In the Four Substances Tang, Radix Rehmanniae Praeparata is the monarch's drug. Radix Rehmanniae Praeparata belongs to the group of blood tonic agents in traditional Chinese medicine, which is sweet, warm and moist, and is good at nourishing the camp-blood, tonifying the blood and nourishing the yin and filling in the marrow.

It is often used in treating blood deficiency and yin deficiency of the liver and kidney. It is used in the treatment of blood deficiency, dizziness, panic and insomnia, menstrual disorders, etc. It is an important medicine for nourishing blood and nourishing deficiency.

Angelica sinensis is the ministerial drug in the formula, Angelica sinensis is also a blood tonic in Chinese medicine, pungent and warm in nature, and mainly enters the blood, which can both tonify and activate the blood, and there is a line in the tonic. It is good at tonifying blood and regulating menstruation, activating blood circulation and relieving pain, moistening the intestines and relaxing the bowels, and is the holy medicine for tonifying blood.

It can be used for all signs of blood deficiency, blood stasis, irregular menstruation, amenorrhea and dysmenorrhea. It can also be used for cold abdominal pain, bruises, carbuncle sores, wind-cold paralyzing pain, blood deficiency, intestinal dryness and constipation.

In this formula, Paeonia lactiflora (white peony) is used as an adjuvant. Paeonia lactiflora also belongs to the category of blood tonic in Chinese medicine, with an acidic and cold flavor, nourishing blood and astringing yin, softening the liver, relieving pain and calming liver yang. It is often used in treating deficiency of Liver-Blood and irregular menstruation, such as deficiency of Liver-Blood, pallor, dizziness, panic attacks and irregular menstruation.

It is also used for liver and spleen disharmony, pain in the chest, hypochondrium and abdomen, and contractile pain in the limbs, to nourish blood, soften the liver and relieve pain, regulate the liver and spleen, and restore the pain caused by loss of nourishment to the meridians due to yin deficiency. It can also be used for headache and dizziness caused by hyperactivity of liver yang.

In this formula, chuanxiong is the enabler, chuanxiong belongs to the category of blood-activating and pain-relieving medicines in traditional Chinese medicine, it is pungent, dispersive and diffusive, it can not only activate blood circulation and eliminate blood stasis, but also can move qi and relieve pain, it is the "qi medicine in blood", it is capable of promoting the circulation of qi and blood and commonly used in the treatment of many pains caused by qi stagnation and blood stasis in the thorax, abdomen and other pains.

Meanwhile, Rhizoma Ligustici Chuanxiong is good at "regulating menstrual flow and opening up stagnation in the middle", it is a key medicine for gynecology to activate blood circulation and regulate menstruation, and can be used to treat various gynecological diseases such as blood stasis, menstrual dysmenorrhea and so on. It can also be used to treat various gynecological diseases such as blood stasis, menstrual cramps and painful menstruation. It can also be used to treat rheumatism and paralysis, and play the role of dispelling wind and relieving pain.

In conclusion, Four Substances Tang combines the two yin and soft blood replenishers (blood medicines), Radix Rehmanniae Praeparata and Radix Paeoniae Alba, with the pungent, sweet and dispersing Radix Angelicae Sinensis and Rhizoma Ligustici Chuanxiong (qi medicines), and combines the dynamic and static functions, which focuses on nourishing the camping blood and, in the midst of the nourishment, implies the movement of the blood, which nourishes without stagnating the blood, and moves the blood without hurting the blood. From this formula, we can indeed taste the charm of the ancients' subtle combination, and later generations have called this formula the foundation for tonifying Blood and regulating Blood.

Four Substance Soup, a Chinese herbal formula composed of a combination of the medicines Radix Rehmanniae Praeparata, Radix Angelicae Sinensis, Radix Paeoniae Alba, and Rhizoma Ligustici Chuanxiong, whose main effect is to tonify and regulate blood, and which can be regarded as the representative formula of blood tonic, the basic formula for regulating menstruation, and the ancestor of many blood tonic formulas of the later generations.

Four things soup from the Tang Dynasty "fairy authorized to treat injuries and continue to break the formula", "into not easy to read" Wang Jin three said: "four things soup, things, class also, the four are similar, but still each with a sex, each build a merit, and not contrary, so the name four things soup", "into convenient reading - tonic agent" said: "four things soup for blood medicine Zong! ", "all blood tonic formula, and when the four things and also" ......

As a kind of warm tonic herbs, Four Substances Soup can be good for blood deficiency in the clinic, but also sedative, analgesic effect, can moisturize the skin, improve the essence of the spirit, can improve the women's friends of dysmenorrhea, menstrual irregularities and other related symptoms. The main ingredients in the Four Substance Soup each have their own effects, and listen to me in detail.

What are the health benefits of Angelica sinensis, Radix Rehmanniae Praeparata, Rhizoma Ligustici, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba in Four Substances Tang?

I. Angelica sinensis

Angelica sinensis is the dried tuberous root of Angelica sinensis, a plant of the Umbelliferae family. As a traditional Chinese medicine, Angelica sinensis is sweet, pungent, bitter and warm. It enters the liver, heart and spleen meridians.

Efficacy:

• Nourishing and harmonizing Blood, applicable to various symptoms caused by Blood deficiency.
• Tonifying Blood and regulating menstruation, used for blood deficiency in the heart and liver, and can be combined with Chuanxiong Xiong, Radix Rehmanniae Praeparata and Salviae Miltiorrhizae.
• It is used to tonify the heart and blood for heart-blood deficiency caused by various reasons, and can be combined with Radix Rehmanniae Praeparata, Radix Paeoniae Alba, Colla Corii Asini, and Rhizoma Cymbopogon Schisandrae.
• Promoting blood circulation and relieving pain, used for bruises, carbuncle sores and ulcers, rheumatism and paralysis pain and menstrual blood stagnation and abdominal pain.
• Moistening the intestines and relaxing the bowels, used for constipation due to blood deficiency and intestinal dryness.
• Tonifying Liver-Blood, used in cases of Liver-Blood deficiency.

Nutritional value:Angelica is rich in amino acids and trace elements such as iron, calcium, copper, zinc and potassium as well as iron.

2. Mature land

Radix Rehmanniae Praeparata, the traditional Chinese medicine Radix Rehmanniae Praeparata, is the dried root of Radix Rehmanniae Praeparata of the family Xuanzanaceae, which is mildly warm in nature and belongs to the liver and kidney meridians.

Efficacy:

• It is used in treating blood deficiency, dizziness, palpitation, insomnia, irregular menstruation and disintegration, as a blood tonic and yin nourisher. It is also used in treating deficiency of kidney yin, such as hot flashes, steaming, night sweating and spermatorrhea, and thirst, etc. It is the main medicine for nourishing yin.
• Benefiting the essence and filling in the marrow, used for soreness and weakness of the waist and knees due to deficiency of essence and blood in the liver and kidney. Vertigo, tinnitus, premature whitening of beard and hair.

iii,traditional Chinese medicine for the stomach (usually prepared as small dark spherical pills)

Chuanxiong is a warm, Chinese medicinal plant that belongs to the liver, gallbladder and pericardium meridians. It is a blood-activating and blood-sludging medicine that is often used clinically to invigorate blood circulation and expel wind and relieve pain.

Efficacy:

• Activating blood circulation and promoting circulation of Qi, it can be used for symptoms such as abdominal pain due to blood stasis, dysmenorrhea in women, irregular menstruation, menstrual closure, postpartum stasis and so on.
• Promoting qi circulation and relieving pain, used for various pains arising from blood stasis, such as chest paralysis and heart pain caused by qi stagnation and blood stasis, stabbing pain in the chest and hypochondrium caused by stagnation of blood in the liver, and pain from bruises and swellings caused by bruises and injuries.
• Dispelling wind and drying dampness, used for symptoms such as dizziness and dizziness caused by external wind-cold, cold paralysis and spasm, and rheumatism paralysis and pain.

Chuanxiong is rich in volatile oil and rich in niacin, sucrose, polysaccharides, etc., based on a variety of amino acids, vitamins B1, B2, vitamin E, as well as zinc, copper and other trace elements.

IV. Paeonia lactiflora

Paeonia lactiflora.It is the root of Paeonia lactiflora of the buttercup family. It is bitter, sour and slightly cold in nature, and belongs to the liver meridian and the spleen meridian, and is a deficiency tonic drug. Its effects include nourishing blood and astringing yin, softening the liver to relieve pain and calming liver yang.

Efficacy:

• Nourishing blood and astringing yin, it can be used in cases of deficiency of liver and blood such as chest pain, irregular menstruation and disintegration.
• Softens the liver and relieves pain, and can be used for spasmodic pain in the chest, abdomen and joints of the limbs.
• Astringing Yin and stopping sweating, it can be used for Yin deficiency and fever, hot flashes and night sweating diseases.

When these four herbs are paired together to form the Four Substances Soup, they can play their role in tonifying and regulating blood, in which, the ripened land is mainly used to tonify blood.Angelica sinensis tonifies and invigorates Blood, Paeonia lactiflora astringes Yin and nourishes Blood, and Rhizoma Ligustici Chuanxiong enters the Blood division to regulate the qi in Blood in order to comply with the characteristics of "Blood is valued for its circulation" and "tonifying Blood without leaving blood stasis".

Prof. Xu Jiqun's fifth edition of the Formulary states.The whole formula of Four Substances Soup belongs to blood medicines, but the combination is proper, tonifying blood without stagnating blood, promoting blood without breaking blood, dispersing in tonifying, collecting in dispersing, constituting an important agent for treating blood.Wang Ang's Collected Explanations of Medical Formulas describes it as "tonifying yin and benefiting blood", and classifies it as a blood regulator, reflecting the characteristics of this formula.

I deliberately went to check by "" Nanjing University of Traditional Chinese Medicine School of Basic Medical Sciences / Jiangsu Province, the key laboratory of prescription research "published literature" four things soup class formula blood regulating menstrual matching efficacy analysis.

Among them, the blood tonic effect of Siwu Tang was experimentally analyzed, using acetylphenylhydrazine and cyclophosphamide to replicate a mouse model similar to the blood deficiency syndrome of traditional Chinese medicine, and to measure peripheral blood and liver-spleen indices, and it was found that after the administration of Siwu TangDifferent degrees of improvement of blood deficiency symptoms in miceExperiments have confirmed that Si Wu Tang also improves coagulation and anticoagulation balance.

Clinical conditions are more complex, and Chinese medicine practitioners will generally focus on each other's blood tonic and blood regulating formulae according to the patient's individual constitution, while expanding the main treatment conditions by adding or subtracting other Chinese herbal medicines.

Refer to the following herbal remedies:

If blood deficiency is accompanied by blood stasis, it is often combined with medicines that activate blood circulation and eliminate blood stasis, such as Yanhuisuo, peach kernel and safflower. For example, "Jiyin Zangmu" treats stasis with blood stasis, adding saffron, peach kernel, curcuma, and so on.

Blood deficiency with qi stagnation evidence, often with qi medicinal herbs, Chen Pi and other drugs. For example, "Jiyin Compendium" with Xiangshu, Wu Lingzhi name plus flavor four things soup treatment of postpartum not exhausted, abdominal pain.

Blood deficiency and heat evil or heat and poison evidence, often add to clear heat and detoxification medicine, such as choice of scutellaria, Huang Huanglian, gardenia, honeysuckle, forsythia and other medicines, see "medical Zong Jinjian".

If Blood is cold and there is pain in the lower back and abdomen during menstruation, add Cannon Ginger, Cinnamon and Wu Yu to warm the cold. If Qi is deficient and does not take in Blood, add Lucullus Codonopsis, Astragalus and Atractylodes Macrocephalae.

In conclusion, the Four Substance Soup is not set in stone, and can be added or subtracted according to the patient's condition under the dialectic of Chinese medicine.

References:

1. Fan Xinsheng and Chen Fei, "Exploration of the efficacy of the Four Substance Soup-like formula for nourishing blood and regulating menstruation".2013 Volume XV, Issue 2

2. (Qing Dynasty) Wang Zijie, Zhao Xiaoqing. Selected Ancient Formulas of Jiangxueyuan. Beijing: China Press of Traditional Chinese Medicine, 1993:143.

3. Xu Jiqun. The science of prescriptions. Shanghai: Shanghai Science and Technology Press, 1985:98.

4. (Qing) Zhang Bingcheng, ed. The reading of the Chengdu manual. Science and Technology Health Publishing House, 1958:6.

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Hello, I am glad to answer your question. 四物汤是中医经典方药，由地，芍，归，芎四药组成，这个方子的灵感来源于仲景的《金匮要略》，以胶艾汤为基础方加减变化而来，具有补益肝肾，养血活血的作用，针对营血不足，血虚兼有郁滞的一类病证，例如面色萎黄，心悸头晕，乏力气短，月经不调，舌淡脉弱而细，通俗讲，四物汤 The main role is to improve the symptoms of blood deficiency, such as the absence of blood deficiency manifestations do not feel free to use, it has no health effects, the use of a doctor before the need to ask for a face-to-face diagnosis, in line with the indications can be used, not the right evidence of no benefit to speak of.

★Si Muo Di Shao and Qui Xiong, this formula is good for all diseases of the blood family.

• Blood is the material basis for the normal functioning of the body's internal organs, Chinese medicine believes that blood is the essence of nutrients, including the spleen and stomach transport dietary changes in the essence of nutrients and the essence of the kidneys in the birth.
• Blood generated in the spleen, stomach and kidneys, running on the heart, liver, five visceral functions and blood generation and operation can be normal, spleen and stomach, liver and kidney disorders can lead to blood shortage, running obstacles. So the "Nei Jing" said "blood, water and grain of the essence, and adjusted in the five viscera, sprinkled with Chen in the six bowels".
• Simply understood, blood deficiency is a series of clinical symptoms caused by insufficient blood. Weakness of the spleen and stomach and insufficiency of the liver and kidneys are the most common causes of blood deficiency. Weakness of the spleen and stomach is the result of insufficient blood production, while blood storage in the liver can regulate the distribution of blood circulation. Therefore, blood deficiency caused by insufficiency of the liver and kidneys is often accompanied by blood circulation disorders, i.e., blood deficiency with blood stasis.

• Liver and kidney deficiency and blood deficiency are characterized by yellowish color, palpitation and dizziness, lumbar and knee pain and weakness, lack of energy, pale tongue and thin moss, and weak pulse.
• Female blood deficiency patients are mostly liver and kidney deficiencies, liver and blood deficiency, women exist in the special physiological period of menstruation, pregnancy, childbirth and breastfeeding, easy to consume blood, "Nei Jing" said "women's birth, there is more than enough gas, not enough blood to its number of blood also". So women's blood deficiency by menstrual irregularities and low volume performance.
• Among the four substances, Radix Rehmanniae replenishes yin qi in the kidneys, which lays the foundation for the kidney qi to transform blood and provides a source of blood nourishment; Rhizoma Gastrodiae, Radix Paeoniae Alba replenishes liver blood and directly improves the core problem of liver-blood deficiency; Rhizoma Gastrodiae, Rhizoma Gastrodiae, is a member of the family Umbelliferae, which is a family of plants that generally carries distinctive aroma.

★Summary

Four Substance Soup is a classic blood tonic formula for liver and blood deficiencies, liver and kidney deficiencies and set up, where the pathological basis of the existence of liver and kidney deficiencies can be added or subtracted with the combination of the basic formula to nourish the blood to promote blood, but there is no cure-all in traditional Chinese medicine, each of the classic formula has a strict indication, for example, weakness of the spleen and stomach can be caused by blood deficiencies, but can never be the main square, the Four Substance of the cooked ground nourishing and greasy nature of the medicinal properties of the spleen and stomach to influence the transportation and transformation of the spleen and stomach, easy to aggravate the manifestations of the deficiency of the spleen. The four substances are nourishing and greasy in nature. Therefore, even though the four elements have a thousand good things, the use of the right evidence is the key.

Lastly, I hope my answer was helpful.

Note: Hello, I am Chinese medicine Zhu Xuyang, the text refers to the theoretical works of Chinese medicine, combined with personal experience, pictures from the network.

Four Substances Soup is a specialized formula for tonifying blood and a good agent for regulating menstruation. All women with menstrual disorders and prenatal and postnatal diseases can use this formula as a basis for adding, subtracting, diffusing and flexibly adapting. In this formula, Radix Rehmanniae Praeparata nourishes Yin and replenishes Blood; supplemented by Radix Angelicae Sinensis to replenish Blood and nourish Liver, harmonize Blood and regulate menstruation; Radix Paeoniae Alba to harmonize and nourish Liver; Rhizoma Ligustici Chuanxiong to activate Blood and promote stagnation. In the formula, Radix Rehmanniae Praeparata and Radix Paeoniae Lactiflorae nourish Yin and nourish Blood, which are the proper medicines for nourishing Blood; Radix Angelicae Sinensis and Rhizoma Ligustici Chuanxiong are pungent, warm and moist, which can not only flow the blood, but also restrain the pure Yin nature of Radix Rehmanniae Praeparata and Radix Paeoniae Lactiflorae Lactiflorae, which is the qi medicine for Blood. Here, blood deficiency can be supplemented, blood dryness can be moisturized, blood overflow can be stopped, blood stagnation can be carried out. It is an agent that can tonify without stagnation. Notes on Use: 1 When using this formula, the main medicine should be determined by the patient's condition. If tonifying Blood, Radix Rehmanniae Praeparata should be the mainstay; if regulating menstruation, Radix Angelicae Sinensis should be the mainstay; if activating Blood circulation to dispel blood stasis, Rhizoma Ligustici Chuanxiong should be the mainstay, and White Peony is easy to be used as Red Peony; if Liver-Qi is in a transverse state, White Peony should be the mainstay.2 If the Spleen and Stomach are usually weak, with lack of transportation and digestion, and with scanty food and loose stools, Radix Rehmanniae Praeparatae and White Peony should be used with caution. If there is deficiency of qi, add Codonopsis pilosulae and Astragalus to benefit qi; if there is stasis of blood, add peach kernel and safflower to activate blood circulation and remove blood stasis; if there is deficiency of blood with cold, add cinnamon and gunpowder ginger to warm the middle warmer and tonify the yang; if leakage in the middle of the crash, add Colla Corii Asini, Ailanthus and Cimicifuga Root to nourish and stop blood circulation; if there is deficiency of blood with heat, add Dan Pi and Scutellariae Scutellariae to clear the heat and cool the blood.3. This formula is combined with the Four Junes and is called Eight Treasures Soup, and it is served in decoction with ginger and jujube for treating pallor or withering yellow color of the face, dizziness, dizziness, limb This formula is used to treat pale or yellowish face, dizziness, dizziness, limb lassitude, shortness of breath and laziness, palpitation and palpitation, and loss of appetite. This formula with peach kernel and safflower is called Tao Hong Si Wu Tang, which is used for treating women with overdue menstruation, large amount of menstruation, purplish color and thick texture, or lumps, abdominal pain and bloating. This formula with ginseng and astragalus is called Shengjie Tang, which is used to treat menstruation that comes at an early stage, with heavy volume and pale color, weakness of limbs, and tiredness and sadness of the body.

As the first formula for regulating blood, Four Substances Tang was first used in the medical book Xian Zhi Li Qin Ren Jian Secret Formula written by Lin Daoren in the Tang Dynasty to treat traumatic injuries with blood stasis and pain; and later recorded in Taiping Huimin Hejiaobing Fang in the Song Dynasty as the basic formula for gynecological blood nourishment and regulation of menstruation, which is also evolved from the Gum and Ai Tang in the Golden Pillars of the Golden Chamber in the Eastern Han Dynasty by Zhang Zhongjing. Therefore, later generations of doctors also called this formula "the first formula for gynecology".

Four Substances Soup consists of four herbs: Angelica sinensis, Radix Rehmanniae Praeparata, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba, which are known as the Four Substances because they have the characteristics of the four seasons of Spring, Summer, Autumn and Winter: birth, growth, harvesting and storing and are able to regulate blood disorders, tonifying, harmonizing and regulating blood circulation, and also promoting blood circulation, tonifying and stopping blood circulation.

Four Substance Soup is a basic formula commonly used in gynecological clinics for menstruation, bandage, and breast milk, because women are blood-oriented, but it can be used for both men and women to tonify qi and blood, such as dizziness, palpitations, insomnia, fatigue, lack of color, and other qi and blood weaknesses are applicable.

The four herbs in the Four Substances Tang play different roles in the application process, which are analyzed below -

Effects of Rehmannia glutinosa

Filling the bone marrow, growing muscles, generating essence and blood, replenishing the deficiency of internal injuries of the five viscera, promoting blood circulation, benefiting the ears and eyes, and lining the beard and hair.

--Materia Medica

Rehmannia glutinosa is the main herb in Four Substances Soup, which is sweet in flavor and warm in nature, nourishing Yin and nourishing Blood, filling in the essence and marrow, and is an important herb for nourishing Blood. In this formula, the use of Radix Rehmanniae Praeparata, which has the function of nourishing yin and tonifying blood, and cooling blood and benefiting the kidneys, is suitable for symptoms such as lack of color, palpitations and insomnia, dizziness, lumbar and knee soreness and weakness, tinnitus and blurred eyes, graying of the hair, hot flashes and night sweating, and irregular menstruation due to the weakness of the vital essence and blood.

Effects of Angelica sinensis

Angelica sinensis can cure headache, heart and abdominal pain, moisten the stomach and intestines, sinews and bones, skin, carbuncle, pus and pain, and blood and blood.

--Materia Medica

Angelica sinensis is sweet, pungent, warm, and has the nature of hair, so it can nourish blood and activate blood, and is suitable for women's blood deficiency caused by irregular menstruation, dysmenorrhea, amenorrhea and other gynecological diseases, as well as cold pain in the epigastrium and abdomen, constipation, abdominal distension and other symptoms of blood deficiency, and it can moisturize the skin and improve skin color and improve the mood for the blood and regulate the menstruation of the important medicine.

Effects of Chuanxiong

Rhizoma Chuanxiong is also used in the treatment of qi in the blood. Liver bitterness and urgency with Xin tonic, so the blood deficiency of the appropriate; Xin to disperse, so the qi depression of the appropriate.

--Materia Medica

Rhizoma Ligustici Chuanxiong is pungent in taste and warm in nature, and is known for its ability to invigorate blood circulation and promote the flow of qi, so it can regulate qi and blood, dispel wind and relieve pain, and promote the flow of blood and stagnation. It can relieve dysmenorrhea, irregular menstruation and amenorrhea caused by stagnation of blood and qi, as well as headache, breast distension and pain, stabbing pain in the chest and hypochondrium, rheumatism and paralysis, sores and swelling, etc., and is effective in removing blood stasis and promoting blood circulation.

Effects of white peony (Paeonia lactiflora)

White peony is sour in flavor and slightly cold in nature, it has the function of astringing yin and nourishing blood, softening the liver and relieving pain, its astringent function is stronger, so it is strong in relieving pain. It can relieve irregular menstruation, dysmenorrhea, abdominal pain and distension, and pain in the limbs.

Compatibility of formulas

Di Huang into the kidney, strong water Yin; white peony into the liver, astringent yin and blood, the two flavors for the blood of the correct medicine. However, blood deficiency and stagnation, the meridian tunnel can not be slippery and smooth, and fear that the ground, peony pure Yin nature, no warmth and flow of the machine, so must be added to the Angelica sinensis, Rhizoma Ligustici Chuanxiong, pungent and warm and moist, can nourish the blood and blood in the line of the gas in the flow of the person.

-Constant readings

In Four Substance Soup, Radix Rehmanniae Praeparata and Radix Paeoniae Alba are used to nourish the liver and blood, while Radix Angelicae Sinensis and Rhizoma Ligustici Chuanxiong are used to invigorate blood. The combination of the two groups of medicines can nourish Blood and promote Blood circulation without stagnating or hurting Blood, and can be applied to both Blood deficiency and Blood stasis, which can nourish Blood and regulate menstruation, promote Blood circulation and promote Blood circulation, and can be applied to many kinds of Blood disorders.

Contraindications for the application of Si Wu Tang

1. It is not suitable for people with liver depression and yin deficiency and internal heat, manifesting as menstrual pre-menstrual period, disintegration, blood in urine during menstruation and blood in stool;
2. It is not suitable for those who have restlessness of the fetus during pregnancy and those who are irritable and hot;
3. Eat with caution when you have a wind-heat cold.

Four Substance Soup was originally used to treat traumatic injuries with blood stasis and pain, but in later times it was used to treat various gynecological diseases, and was known as the first formula in gynecology, especially for postpartum blood deficiency and blood stasis, and it is the basic formula for tonifying blood and regulating blood medicine. Four Substance Soup has been used for gynecological blood deficiency and stagnation, which manifests itself as dizziness, pallor, and irregular menstruation. In fact, men with blood deficiency (anemia), poor mental status, pale face with weak pulse and dark tongue, also often use Four Substances Tang as the base formula for addition and subtraction. Nowadays, there are a lot of Four Substance Soup-type health products on the market.

The main effect of Four Substances Soup is to tonify and harmonize Blood, treating deficiency and stagnation of Ying and Blood. It is a disease of deficiency of Ying and Blood, with poor blood circulation. The formula mainly contains Radix Rehmanniae Praeparata, Radix Angelicae Sinensis, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba, of which Radix Rehmanniae Praeparata is the monarchical herbs, which is sweet, warm, nourishing and greasy and nourishes the camping and blood. Paeonia lactiflora is acidic and cold, nourishing Blood and astringing Yin, softening the Liver and relieving pain. Rhizoma Chuanxiong is pungent and warm, can promote blood circulation, remove blood stasis and relieve pain, and with the other three herbs, can make tonic without stagnation. Combined with the other three herbs, it can tonify blood without stagnation. The four herbs work together to tonify and harmonize blood. In later times, based on Si Wu Tang, Tao Hong Si Wu Tang was derived to nourish and invigorate Blood, treating those with Blood deficiency and Blood stasis; Ginseng and Astragalus Tao Hong Si Wu Tang tonifies Qi, invigorates Blood and removes Blood stasis, and is a commonly used formula in the treatment of diabetes mellitus and the sequelae of cerebral infarction in the modern era; and Colla Corii Asini Tang adds Colla Corii Asini, Ailanthus Artemisiae, and Glycyrrhiza Uralensis on top of Si Wu Tang, in order to nourish Blood and stop Blood stasis and regulate menstruation to stabilize pregnancy.

It should be noted that although Four Substances Tang is the basic formula for Blood division diseases, the key lies in the changes in the dosage of the medicines used and the amount of medicines used. For example, in Blood deficiency with Blood stasis as the main cause, White Peony should be changed to Red Peony; in those with Blood heat, Radix Rehmanniae Praeparatae is easily replaced by Radix Rehmanniae Pterygosperma, the dosage of Rhizoma Ligustici Chuanxiong should be reduced and that of Radix Rehmanniae Pterygosperma increased. In conclusion, the four herbs in Four Substance Soup mainly play a role in tonifying and harmonizing blood, and can regulate irregular menstruation, dysmenorrhea, menstrual closure, postpartum blood deficiency and blood stasis in women, and can also be used in men with excessive blood loss from trauma and anemia.

Text: Dongdong Lu, Master's Degree Candidate, Department of Men's Medicine, China-Japan Friendship Hospital

Reviewed by: Wang Chuanhang, Chief Physician, Department of Men's Medicine, China-Japan Friendship Hospital

Four Substances Soup, known as the first formula in gynecology, consists of four herbs: Radix Rehmanniae Praeparata, Radix Angelicae Sinensis, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba, and is used in treating headache and dizziness due to Blood deficiency, women's irregular menstruation, and dysmenorrhea. This formula is the basic formula for nourishing Blood and regulating menstruation, and can be varied by addition, subtraction and modification according to the evidence. For example, if there is Qi deficiency, ginseng and astragalus can be added; if there is bruising, peach kernel and safflower can be added; if there is cold in Blood deficiency, cinnamon and ginger can be added; if there is heat in Blood deficiency, Huang Lian and Scutellaria baicalensis can be added; if there is excessive menstruation and post-partum uterine bleeding, Colla Corii Asini, Ailanthus charcoal can be added, and so on.

The four herbs in this formula all play different roles: Di Huang is the monarch, nourishing Yin and blood, benefiting the essence and marrow, and can be used for the lack of menstrual blood and the face, palpitations and insomnia, dizziness, tinnitus, lumbar and knee soreness and weakness, hot flashes and night sweating, menstrual disorders, and so on. Angelica sinensis is an important medicine for nourishing blood and regulating menstruation, it can nourish and activate blood, and can be used for irregular menstruation, dysmenorrhea, amenorrhea and other conditions caused by blood deficiency in females, it can also regulate emotions, moisturize skin and nourish skin. Rhizoma Ligustici Chuanxiong promotes Qi and blood circulation, dispels wind and relieves pain, promotes blood circulation and stagnation, relieves dysmenorrhea, irregular menstruation and amenorrhea caused by stagnation of Qi and blood circulation, and is also effective in dispelling blood stasis and promoting blood circulation in breast distension, stabbing pains in the chest and hypochondrium, as well as rheumatism paralysis and paralytic pains. White peony nourishes blood and astringes yin, rubs the liver and relieves pain, relieves irregular menstruation, dysmenorrhea, abdominal pain and fullness.

This formula combines Radix Rehmanniae Praeparata with Radix Paeoniae Alba to nourish the liver and blood, and Radix Angelicae Sinensis with Rhizoma Ligustici Chuanxiong to invigorate blood. The two groups of herbs work together to nourish and promote blood circulation without damaging or stagnating blood, and can be used for both blood deficiency and blood stasis. This formula is not only for gynecology, but also has a good effect on regulating male blood deficiency.

Four Substance Soup is known as the first sacred formula of gynecology, which is mainly used to regulate irregular menstruation, deficiency of qi and blood, especially dysmenorrhea caused by blood stasis.

Chinese medicine for the four things soup records, "Song-Taiping Huimin Hejiaobu Fang" and "immortal authorization of injuries interrupted secret formula", and the composition of the four things soup are the four kinds of drugs Angelica sinensis, ripened ground, rhizoma ligustici chuanxiong, white peony, and the later also based on the four things soup, add and subtract, can be symptomatic treatment of different treatments.

Regardless of how the Four Substances Tang is added or subtracted, but in general the Four Substances Tang cannot be separated from the four herbs: Angelica sinensis, Radix Rehmanniae Praeparata, Rhizoma Ligustici Chuanxiong and Radix Paeoniae Alba.

Angelica sinensis] According to traditional Chinese medicine, Angelica sinensis tonifies blood, regulates menstruation, relieves pain, moistens the intestines and passes stools. Commonly used to treat blood deficiency, yellowish color, irregular menstruation, menstrual pain, cold abdominal pain, intestinal constipation, etc., but also can be used to treat bruises, canker sores and sores.

[Radix Rehmanniae] According to Chinese medicine, Radix Rehmanniae nourishes yin and replenishes blood. The Compendium of Materia Medica records that ripe earth fills the bone marrow, long muscles, blood, supplement the five viscera, internal injuries and deficiencies, through the bloodstream, ear and eye, black hair, men's five labor seven injuries, women's injuries in the cytosol leakage, menstruation discomfort, the fetus and birth of a hundred diseases. Therefore, ripe earth can not only nourish yin and tonify blood, but also good at treating men and women's essence and blood deficiency.

Rhizoma Ligusticum Chuanxiong] According to Chinese medicine, Rhizoma Ligusticum Chuanxiong activates blood circulation and promotes circulation of Qi, dispels wind and relieves pain. Commonly used in menstrual disorders, menstrual cramps, abdominal pain, bruises, headaches, rheumatism and paralysis pain. Rihuazi Materia Medica" records that it can cure all wind, all gas, all labor injury, all blood, tonifying the five organs, strengthening the muscles and bones.

White peony] According to Chinese medicine, white peony calms the liver and relieves pain, nourishes blood and regulates menstruation, and astringes yin to stop sweating. It can be used for headache, dystocia, abdominal pain, contracture of the limbs, menstrual disorders, spontaneous sweating, night sweating. It can be said that the pain-relieving effect of white peony is very strong, the famous doctor Zhang Xichun treatment of pain will add white peony this flavor of Chinese medicine.

The above is an introduction to the efficacy of various Chinese medicines, and Chinese herbal formulas are generally characterized by the need for a ruler, ministers and auxiliaries. In this formula of Four Substance Soup, Angelica sinensis nourishes blood, nourishes the liver, harmonizes blood and regulates menstruation as the ruler; Radix Rehmanniae Praeparata nourishes yin and nourishes blood as the minister; Paeonia lactiflora nourishes blood, softens the liver, and harmonizes the camp as the adjuvant; Rhizoma Ligustici Chuanxiong invigorates blood and moves the qi, unimpeded qi and blood, and as the ambassador. The combination of the four flavors has the effect of tonifying without stagnation, nourishing without being greasy, nourishing Blood and activating Blood, which can harmonize Ying and Blood.

Therefore, it is not for nothing that Four Substance Soup is known as the first holy formula in gynecology.

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