Why do they say that a medicine is poisonous?
First of all, we have to define the meaning of "poison" in the title. Poison in a broad sense, is the wikipedia definition, but also the public understanding of the concept: poison; poison: chemical substances in the environment, under certain conditions into the body, can be biochemical or biophysical effects with the body, and then interfere with or destroy the normal physiological functions of the body, causing temporary or persistent pathological state, or even life-threatening.
The broad sense of poison, in terms of drug toxicity, Western medicine is closer to this understanding; and Chinese medicine poison, more inclined to the narrow sense of the "poison", every kind of Chinese medicine can play a role, is the use of its own "toxicity". Therefore, we will only discuss the "toxicity" of Chinese medicine. First of all, a simple example: the use of bitter cold Chinese medicine to clear heat, the drug itself is "cold", it has a bias, if used for cold or weak, is cold on cold, reflecting the "toxicity"; if used to treat heat, heat disease cold treatment, that is a good medicine, this is the "toxicity"; this is a good medicine. This is the theory of "bias against bias". It is also handed down the saying that "medicine is three times poisonous". So the narrow sense of "poison" is the bias of the drug.
The earliest surviving work on traditional Chinese medicine, Shennong Ben Cao Jing, categorizes traditional Chinese medicine into upper, middle and lower grades, with upper grades being "non-toxic", middle grades being "poisonous or non-toxic" and lower grades being "more poisonous". The top grade is "non-toxic", the middle grade is "poisonous or non-toxic", and the bottom grade is "more toxic". Generally speaking, the drugs that attack diseases and cure diseases are called toxic, and the drugs that are taken for a long time to replenish the deficiency are regarded as non-toxic. Currently included in the State Council's "Medical Toxic Drugs Management Measures" there are 28 varieties of traditional Chinese medicine: arsenic (red arsenic, white arsenic), arsenic, mercury, raw strychnine, raw Chuanwu, raw Caowu, raw white aconite, raw epiphyllum, raw half-summers, raw southern star, raw croton, spotted fibers, red niangmu, green niangmu, raw Gansui, raw wolfsbane, raw rattan, raw Qianjinzi, haunted sunflower, raw Tianxianzi, XueShan a artemisia, red ascending dan, white descending Dan, toadshell, YangJinHua, toadstools, and so on. Toadstools, toadstools, flowers, red powder, light powder, and andrographis.
In addition to the toxic herbs listed above which have clear toxicity, many of the remaining herbs still have some toxic side effects, such as Guan Mutong, Cang Zi Zi and Shan Dou Gen. According to the theory of using bias to curb bias, basically any Chinese medicine that can be used to cure a disease is toxic in its own bias. The causes of poisoning in the application of Chinese medicines include: excessive dosage; taking forgeries by mistake; improper concoctions; improper preparation and serving methods; and improper compounding. In addition, improper medication, self-medication and individual differences are also causes of poisoning of Chinese medicines.
That's why it's a medicine.
Correct treatment of the toxicity of Chinese medicines is the guarantee of safe use of medicines. There are many records on the toxicity of Chinese medicines in the herbs of the past dynasties, which is a summary of the experience of the predecessors and is worth learning from. At present, there are tens of thousands of varieties of Chinese medicines, and only about 100 of them have been reported to be poisonous. Therefore, most of the Chinese medicines are still relatively safe, which is one of the major advantages of Chinese medicines!
Reference: Medical Science, Shao Kuiqing, "How to Recognize the Toxicity of Chinese Medicines?
National Chinese Medicine Professional and Technical Qualification Examination Book (Chinese Medicine Specialty)
This answer was provided by Qian Weiliang, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, China
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Is medicine three poisons, this poison, there are broad and narrow sense of the points, Chinese medicine to plant-based, plants are divided into two categories, those of the nature of the flat taste and sweet and no partiality, more than five grains and cereals, in order to support the people's positive energy, the sex of the bias of the more for the use of drugs. The internal scripture said: poisons attack the evil, five grains for nourishment.... The so-called poison to attack evil, is to use the bias of drugs to correct the human body bias. Such as the human body fever must be used to clear the plant's cold bias to heat, the human body is cold, the use of warm plants to correct the human body's cold, the plant's bias is the broader sense of the poison. Is medicine three poisons refers to long-term use of the human body is a side effect, such as heat disease has been non-stop use of cold medicine, it will be overkill, caused by the body cold. The internal scripture pointed out that: long and increase gas, the normal of materialization, gas increase and long, the cause of premature. It is said that this 祌 partiality of the drug dosage is appropriate, in order to get rid of the disease, so that the human body to achieve a balance of yin and yang, with more will be harmful to the body. For those who are strong, harsh and fierce is the essence of toxicity, after artificial special concoctions, reduce the toxicity of the controlled dosage, the same Xiang used in the clinic, in order to correct the human body bias, to maintain the balance of yin and yang.
Whether it is traditional Chinese medicine or Western medicine, the saying that "medicine has three poisons" is reliable. Simply put, drugs into the body to fight diseases, often difficult to have a certain point, in the fight against the treatment of disease at the same time, the human body's other tissues and normal healthy cells may also be affected by the drug, which is "is a drug three poisons," the fundamental reason.
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Metabolism and excretion of drugs
Generally, medications are taken to combat illness, such as acetaminophen for antipyretic and analgesic effects, and taking it when you have a fever generally lowers your temperature quickly and with exacting results.
Simply put, the metabolic excretion process of drugs is: when the drug enters the body, especially oral drugs, the first is absorbed through the gastrointestinal tract, the absorbed drug enters the liver, metabolized under the action of various enzymes, and then in the exercise of its therapeutic role in the body, after the treatment and fight against pathogens, metabolism of the completed drug through the excretory system, usually the kidneys out of the body.
After reading this process, we can understand, the drug in the body to go through the gastrointestinal tract, if the nature of the drug on the gastrointestinal tract has stimulation, then it will produce gastrointestinal side effects; to go through the liver metabolism, if the drug has a certain degree of toxicity to the liver, then it may cause liver function abnormalities, such as statin drugs for liver function problems should be banned; to go through the renal excretion, a lot of drugs will be the formation of a kidney The burden of many drugs on the kidneys, such as amoxicillin, renal insufficiency should be taken with caution. From these aspects: is medicine three times poison is very reasonable.
Medication is a combination of benefits and risks
Drugs enter the body to treat the disease, this and that side effect will inevitably occur, in addition to the above mentioned side effects in the metabolic process, there are also side effects brought about by the therapeutic effect, such as cancer radiotherapy drugs, in killing cancer cells at the same time, the human body's healthy cells will inevitably be damaged, by the same token, the other drugs in the treatment of disease at the same time, inevitably will have an effect on the Other drugs, while treating diseases, will inevitably affect other normal functions of the human body. For example, aspirin enteric-coated tablets, taken in low doses, can prevent cardiovascular diseases and strokes, but when taken for a long period of time, due to its resistance to platelets, it may also cause serious problems such as internal bleeding.
But to stop taking medication because there are risks associated with it? Of course not, in fact, not only medication, but any thing in the world is a combination of benefit and risk assessment, what do you mean by benefit and risk assessment.Let's take a simple example that isn't medicine: you're going out to do something important today, but there's a chance that you might fall if you go out, so who's going to stop going out because they're afraid of falling? Because the chances of you falling are small and the risk is small, but what you are going out to do is important, so you would definitely choose to go out and do the errand rather than not go out for fear of falling.
The same applies to taking medication, if the disease is in urgent need of treatment, and if not treating it will create more serious problems, then it is necessary to take medication, injections, and even surgery. Never be afraid of the side effects of drugs and ignore the treatment of physical illness.
Regarding the situation of "three poisons in a drug", there are still a lot of real-life drug instructions are not labeled, but the actual occurrence of the situation, you are welcome to discuss in the comments below!
Good question! Why is it said that "medicines are poisonous"?The main reason is that with efficacy comes side effects, and without side effects it's a placebo!
Regardless of Chinese or Western medicine, as long as this drug has an effect on the human body and has an impact, then it is bound to have side effects!
For example, the western medicine inside the amlodipine, which is the most commonly used blood pressure medication, this drug is very effective in lowering blood pressure, but there is a side effect, edema, after eating the gums are easily swollen, calves and ankles are easily swollen, why? Because the principle of this drug to lower blood pressure is to diastole blood vessels, blood vessels diastole, water is not easy to discharge from the body, people are naturally prone to swelling, if this drug to eat a little bit of swelling, basically blood pressure can not be lowered. Chinese medicine is the same reason, you say Huanglian clear pill this medicine, clearing heat to remove fire is very effective, but you give the spleen and stomach cold people try to eat, immediately on the diarrhea, why? Because cold is its own role!Even the best medicines have adapted symptoms, diseases and people, and when used correctly, ginseng can save lives! Used wrongly, ginseng can also kill!
Besides, talking about efficacy and side effects without the dosage is just a joke.
Is arsenic poisonous? Trace amounts of arsenic are now used to treat leukemia; is plain water safe? If you drink 10 liters of water at once, you are guaranteed to be sent to the emergency room!
So is the medicine three poisons, this sentence is the first is nonsense, the second mislead a lot of people, should see a doctor not see a doctor, should take medicine not take medicine, until the disease dragged to the point of no longer go to the cure has been too late!
Is medicine three poisons is about not eating more than you should not eat the drug, do not look for disease to find medicine to eat, from ancient times, said the poison, that is, let people usually take good care of the body, do not wait to have a disease, and also affect the physical and mental health, to do a good job of the body to self-check the symptoms of the disease, feel uncomfortable in the daily diet, rest and relaxation attention to improve the concerns of the medication by eating and resting.
Simple cold in fact do not need to take medicine, in a week to pay attention to rest, drink more water can also be good, just now the people are pretentious, there is a disease to grab medical treatment, but also the medical profession of the chaos of the line of people to eat medicine to eat the human body bad, originally simple inflammation used to be the use of penicillin, spanking injection, the effect of a good price is also cheap, slowly, in order to profit-driven, speak of penicillin replaced by cephalosporins, profits, and the effect of the penicillin is not much different from that time after using cephalosporins. Penicillin is not much different, then after the use of cephalosporin, do not feel very useful, and then appeared the pioneer, slowly the body produces resistance, and then the use of penicillin has been no use. To put it bluntly, it is a person who treats people badly.
Whether the medicine is toxic or not, when you are sick you should see and eat or take medicine, some diseases can not be carried, need to be treated or timely medical advice and medication.
Is to be three poisons of the concept of clinical is also quite important, people take drugs some antibiotics will damage the internal organs of the human body, long-term use will have toxic side effects, so the medical profession according to the damage of the drug to the body, gradually improve and rationalize the research of new drugs, so that the drug to the body to reduce the damage.
Medicine to cure the right disease is a good thing, cure bad is poison. So people still follow the laws of nature, according to the law of sunrise and do, sunset and rest, do not stay up all night, eat a reasonable diet, and then poisonous drugs will be far away from you, do not talk about where the three poisons come from.
1.every medicine has its side effect, which refers to each drug, the general publicwholeWhen medication is used to treat a disease, there is always the possibility of an adverse reaction, i.e., a toxic side effect of the drug. For example, the probability of a certain side effect occurring in a certain drug is 1.5%, that is, all the people who use this drug, 15 out of 1,000 people may occur, and 985 people did not occur. A lot of people think that they cannot use a drug when they hear about its toxic side effects, which is of course a wrong understanding of the whole probability event.
It is an intrinsic effect of a drug that occurs at a therapeutic dose that is unrelated to the therapeutic purpose and may cause discomfort or distress to the patient, but is generally mild and mostly a functional change that can be recovered. Side effects of drugs can often be corrected or eliminated. For example, the anti-hypertensive drug nifedipine has the side effect of increasing the heart rate, metoprolol has the side effect of slowing down the heart rate, the two together have synergistic antihypertensive effect, and the side effect of affecting the heart rate can be canceled out or reduced.
It is the residual biological effect when the plasma drug concentration has fallen below the threshold concentration after the drug has been discontinued. This reaction may be very short-lived, such as the hangover phenomenon the next morning after taking barbiturate hypnotics; it may also be relatively long-lasting, such as the long-term application of adrenocorticotropic hormone, due to the negative feedback effect on the anterior pituitary gland caused by the adrenal cortex atrophy, once the drug is discontinued after the adrenocortical hypokinesia, it is difficult to recover within a few months. A few drugs can cause permanent organic damage, for example, large doses of furacil and streptomycin can cause permanent deafness.
Thank you for your question.
(1) As the saying goes, "medicine is a poison". This should be a phrase we have heard more often in our daily life. It should be about the adverse reactions or toxic side effects of drugs, i.e. every drug has its corresponding adverse reactions. Drugs, a double-edged sword, can cure diseases, but also may cause diseases or produce adverse reactions.
(2) In western medicine, "poison" in a narrow sense can refer to toxic reactions, including acute toxic reactions and chronic toxic reactions; "poison" in a broader sense can also include side effects, toxic reactions, allergic reactions, secondary reactions, after-effects, teratogenicity, carcinogenesis, mutation and so on. Mutagenesis, etc. To cite a few classic examples of century-old drugs, such as aspirin, antipyretic and analgesic drugs, clinically used for colds and fever, muscle pain and other pain, anti-rheumatism, anti-thrombosis, which also has its adverse reactions, such as anti-rheumatism, long-term high-dose, gastrointestinal reactions, serious gastric hemorrhage and perforation of the stomach, allergic reactions, asthma aspirin, etc.; penicillin, anti-infective drugs, in the process of using the allergic reactions, such as anaphylactic shock, can also occur. Allergic reactions, such as anaphylaxis, drug rash; nitroglycerin, the treatment of angina pectoris drug, in the process of use may also appear skin flushing, throbbing headache and other adverse reactions.
(3) When it comes to Chinese medicines, many people believe that Chinese medicines are homologous with food, purely natural and free of toxic side effects, which they consider to be the greatest advantage of Chinese medicines. In fact, "Chinese medicine is non-toxic" is a wrong view. Remember, Chinese medicine is also medicine. Improper use of Chinese medicines can still cause serious consequences and even lead to death. Again, to cite a few examples, such as the Belgian weight-loss Chinese medicine poisoning incident, the weight-loss drug contains Guangpuji, resulting in patients with anemia, proteinuria, renal failure, etc.; Japan's small chaihu soup poisoning incident, small chaihu soup caused interstitial pneumonia, and so on.
The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.
The drug is a "poison", in which the"Poison" actually refers to adverse drug reactions... All clinically applied Western and Chinese medicines (Don't think Chinese medicine is safe.), all of them may bring some adverse reactions, either mild or severe. In mild cases, there will not be any uncomfortable symptoms, in severe cases, it may bring serious complications.
Two examples.aspirin (loanword)As a century-old classic drug, it is widely used to fight platelet aggregation and inhibit thrombosis. However, while taking aspirin, theMay cause damage to the stomach, in mild cases, symptoms of stomach upset, and in severe cases, serious adverse reactions such as stomach bleeding may occur.
Then there's the hotly debated the other dayChai Hu InjectionProhibited for use in children, this drug has been used in the clinic for more than 70 years, is also the world's first Chinese medicine injection varieties, fever reduction effect is obvious, but also but happened a lot ofAdverse reactions include anaphylaxisThe State Food and Drug Administration (SFDA), based on the results of adverse reaction monitoring and safety evaluation, made a re-evaluation and revised the instruction manual, which requires that it be prohibited for children.
While it is true that medications may have adverse reactions associated with theWhen the medication is taken correctly, the incidence of these adverse reactions is significantly reduced, and most people do not even experience any significant discomfort. Therefore, it is not recommended to take any kind of medication without authorization, it should be taken as prescribed under the guidance of a doctor and pharmacist.
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Hello, this question I can answer you, I am a pharmacist in charge, I hope my answer is helpful to you, welcome to pay attention. Any questions about medication, please leave a message or private message, will certainly reply!
Before discussing this issue, we first need to understand what is a drug?
Basic concept of drugs: substances used for the prevention, diagnosis and treatment of human diseases, the purpose of regulating human physiological functions and stipulating the indications or functions, dosage, including Chinese herbal medicines, Chinese medicine tablets, proprietary Chinese medicines, chemical raw materials and their preparations, antibiotics, biochemical medicines, radiopharmaceuticals, serums, vaccines, blood products and diagnostic medicines, and so on.
Both Chinese and Western medicines are chemical substances in nature. We call them medicines because these chemicals regulate human physiological functions.
The effects of drugs acting on the organism are broadly categorized into two groups: those that achieve preventive, diagnostic, and therapeutic effects, known as therapeutic effects; and those that produce adverse reactions to the drug, that is, unintended harmful reactions unrelated to the purpose for which the drug was administered.
The reason for the therapeutic effects and adverse reactions is that a very large majority of medications are not 100 percent selective, but only high or low. Almost all medications have adverse reactions, and medications are like a double-edged sword, with both advantages and disadvantages.
For example, Omeprazole sodium, a common gastric protector, is used to treat gastric ulcers, duodenal ulcers, and reflux esophagitis. Its common adverse reactions include headache, diarrhea, abdominal pain, nausea, and flatulence. Anti-tumor drugs can inhibit the value-added of tumor cells, but also inhibit the proliferation of normal body cells, so it will produce more adverse reactions, such as inhibition of the bone marrow hematopoietic system, alopecia, reproductive toxicity, nausea, vomiting, diarrhea, and neurotoxicity. Diuretic antihypertensive drugs lower blood pressure while increasing the frequency of urination.
The adverse effects of drugs and their therapeutic effects are not absolute. For example, quetiapine fumarate is used in the treatment of schizophrenia, but the drowsiness it produces is sometimes utilized to treat insomnia. Another example is metformin, a drug used to treat hyperglycemia, where weight loss is an adverse reaction, but this drug is especially suitable for patients who are overweight.
All medicines have a certain degree of "toxicity". But don't be afraid to take medication. If the dosage and usage are strictly controlled, and the therapeutic benefits are greater than the "toxicity" of the drug, then the drug should be taken, as the saying goes, to choose the lesser of two evils.
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The phrase "it's the medicine that counts" is known to almost everyone. However, I have searched for hours without finding the exact source of this saying, but I don't think that this affects our use of it in any way. In my opinion, there are two situations in which the phrase is generally said, see.
One, when you don't want to take your medication.There is often such a person in life, they are obviously already sick, the doctor also said that the need to take medication, he still hold out not to take medication, and said: medicine is three times poisonous. The consequences of doing so will often lead to aggravation of the condition, and some even have to be hospitalized; there are some people who are not fully well without authorization to stop taking medication, will lead to repeated illness. We have to remember, any drug will have certain side effects, but should be eaten still have to eat, never because of the fear of taking medication for fear of side effects and delayed treatment.
Secondly, when scientific medication is taken.There is also a group of people who, when taking medicines as prescribed by their doctors, will know that medicines have certain side effects, which are determined by the two sides of medicines, i.e. curative and pathogenic. They listen to their doctors or pharmacists, take their medicines on time and according to the dosage, do not increase or decrease the dosage arbitrarily, and if they find that they are not feeling well, they will contact their doctors in time to determine whether they need to stop taking their medicines, rather than making a decision blindly and privately. Because they know very well that medicines are three times poisonous, but as long as they are used scientifically, there is no need to be afraid.
It is important to note that the three poisons of medicines do not only refer to Western medicines, but in recent years, the side effects of Chinese medicines have also aroused people's concern. The view that Chinese medicine is purely natural and free of any toxic side effects is obviously wrong. For example, the epiphyllum can cause cardiotoxicity, flaxseed contains muscarinic choline and phenolic components, acting on the central nervous system, causing toxic reactions, Guanmutong can cause nephrotoxicity and so on.
For is medicine three poisons, we must look at the whole picture, scientific choice and take drugs, not just take drugs, can effectively avoid or reduce the occurrence of adverse drug reactions.
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