Ketoacidosis is a serious acute complication of diabetes. If treatment is not timely, it can often be life-threatening and lead to death. The occurrence of ketoacidosis is induced by the serious lack of insulin and infection, trauma and other reasons, so it will inevitably cause metabolic disorders in the body. First of all, there is a significant increase in blood glucose (due to glucose can not be fully utilized resulting in elevated blood glucose), or even up to 500 mg% or more. In addition, due to the body of anti-insulin substances such as glucagon, growth hormone and corticosteroid can promote accelerated lipolysis, fatty acid increase, and produce a large number of ketone bodies, and due to the absolute lack of insulin, ketone bodies can not be metabolized by the body's tissues and utilization, which gives rise to ketosis. Ketosis includes hyperketonemia and ketonuria. Ketone bodies are acidic substances, if the acid continues to accumulate in the body, ketoacidosis will occur; polyuria, polydipsia, irritable thirst, dehydration, respiratory compensatory deepening accelerated, expiration with ketone body odor (rotten apple smell), blood pressure drop, shock, coma and a series of symptoms, and even death.