Patchouli Oral Liquid is safe and non-life-threatening when taken with cephalosporins; however, Patchouli Zhenqi Water taken with cephalosporins is associated with adverse reactions, which can be life-threatening in isolated, severe cases.

Because there is no alcohol (ethanol) in Patchouli Oral Liquid, it will not cause a disulfiram-like reaction with cephalosporins. It can be taken with confidence.

While patchouli contains alcohol (ethanol), it cannot be taken together with cephalosporins. Because alcohol (ethanol) in the body by the ethanol dehydrogenase enzyme decomposition into acetaldehyde, acetaldehyde by the enzyme dehydrogenase decomposition into acetic acid, part of the acetic acid decomposition into carbon dioxide and water, out of the human body, and another part of the acetic acid will be converted into fat, hoarding in the body. The cephalosporin drugs, especially the cephalosporin drugs containing the structure of "Methylthiotetrazole", will inhibit the enzyme of acetaldehyde dehydrogenase, so that acetaldehyde accumulation in the body, resulting in a series of adverse reactions, such as facial redness, blurred vision, headache, nausea, vomiting, respiratory difficulties. Among them, patients with ethanol allergy or those who are frail and suffer from a variety of geriatric diseases may be life-threatening.

In addition, the image in your question is an image that was previously circulated on the internet. The description of this picture: "Huo Xiang Zheng Qi cannot be taken together with Cephalosporin" is not very accurate. Because there are five kinds of Chinese patent medicines on the market, namely: Huo Xiang Zheng Qi Pills, Huo Xiang Zheng Qi Capsules, Huo Xiang Zheng Qi Water, Huo Xiang Zheng Qi Oral Liquid and Huo Xiang Zheng Qi Compound. Only Huo Xiang Zheng Qi Shui contains alcohol (ethanol), while the other four types of Huo Xiang Zheng Qi do not have alcohol (ethanol). Therefore, the words in the picture should be changed to "Patchouli Zhengqi Shui should not be taken together with cephalosporins, nausea and vomiting will occur, and individual patients will have difficulty breathing, and those who are allergic to ethanol may even have life-threatening injuries. When taking cephalosporins, you must choose patchouli zhengqi pill, patchouli zhengqi capsule, patchouli zhengqi oral liquid and patchouli zhengqi combination, not patchouli zhengqi water."

The above is a personal argument, not as a medication guide, please use the medication after diagnosis by a TCM doctor, if you have any questions, please leave a comment at the bottom of the article.

The authoritative interpretation of Pharmaceutical Affairs, unauthorized reproduction, plagiarism will be punished.

Patchouli Zhenqi Shui (Oral Liquid) is an oral preparation made from the Chinese medicinal herbs Cangzhu, Chenpi, Houpu, Angelica dahurica, Poria, Dabu Pi, Semenxia, Glycyrrhiza glabra, Huozhuang oil, Perilla frutescens leaf oil extracted from the active ingredients through the process of distillation, alcoholization and containing ethanol, mainly used for colds, sunstroke and nausea and vomiting diarrhea caused by colds and flu, and other gastrointestinal symptoms of the treatment.

Cephalosporin antibiotics and amoxicillin both belong to the beta-lactam ring antibiotics, drinking alcohol within three days of use or drinking drinks containing alcohol within three days of the drug can occur biflurane-like reaction, which will be flushed face, tachycardia, nausea, vomiting, headache and other symptoms of toxicity, especially for arrhythmia of the heart disease patients are more likely to occur.

That's why it is said that Patchouli Zhengqi Shui (Oral Liquid) contains ethanol, and when taken together with cephalosporin antibiotics and amoxicillin, it can cause a disulfiram-like reaction, which can be life-threatening in severe cases.

According to Xiao Ke, since the oral solution and injection of traditional Chinese medicine contain ethanol components, avoid static injection of traditional Chinese medicine at the same time when administering antibiotics intravenously with cephalosporins, so as not to cause disulfiram-like reactions and other adverse reactions.
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Recently, everyone in the circle of friends may have seen a similar message, "patchouli liquid and cephalosporin, amoxicillin can not be taken together, eat immediately killed." This crazy news is actually the essence of - take antibiotics do not touch alcohol. But this message is inaccurate, patchouli Zhengqi liquid contains nearly 50% alcohol, if taken together with cephalosporin, amoxicillin and other antibiotics, a disulfiram-like reaction will occur. However, this does not mean that whenever they are mixed together, there will be a reaction. Because, he is a certain probability, not to mention the claim of immediate death.

Disulfiram-like reaction is when we take antibiotic drugs like cephalosporin, amoxicillin and other antibiotic drugs along with something containing alcohol, which produces a manifestation similar to the action of disulfiram and alcohol, causing an adverse reaction in the body. Mild adverse reactions may include flushing, blurred vision, dry mouth, dizziness, palpitations, nausea, vomiting, dyspnea, etc. Severe adverse reactions may include a drop in blood pressure, acute heart failure, acute liver damage, convulsions, shock and even death. Generally speaking, the severity of adverse reactions is positively correlated with the amount of alcohol taken. Symptoms may be more severe in those who are sensitive to alcohol, the elderly, and children.

If you unknowingly take antibiotics with alcohol, you need to stop the medication immediately. Depending on the severity of the adverse reaction, you may choose to relieve yourself or seek emergency medical attention. At present, in addition to antibiotics, there are also metronidazole, omeprazole, phenelzine and other drugs should not be taken with alcohol, need to pay attention to. In addition, children with fever such as taking cephalosporins, also do not use alcohol wipes to reduce fever, so as not to cause adverse reactions.

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