Agree with the upstairs point of view. Not against nor fear, the amount of disease are available. However, it is not Li Shizhen first advocated, is Meng Chang Shu Ben Cao first loaded, can not be trusted.

Although aconite and aconite are the lateral and main roots of the same plant, the eighteen antithetical words aconite are opposed to shellac, gua vulgaris, semixia, bai zhi, bai bian, and bai hyacinth. Because of the aconite epiphyllum great heat to hurt fluid, other shellfish, guayule and other moisturizing and clearing heat, so the nature of the opposite. However, do not seek hot and dry epiphyllum, other cool and moist nature to be used together is also possible, such as the treatment of cold drinks on the reversal of abdominal pain in the red pill formula, aconite and the opposite drug half-summers with the same medicine, the opposite of each other, in order to enhance the dispersal of cold drinks to lower the reversal of the work.

Epiphyllum, the root of the aconite is concocted. Although it is said that "half piper shell convergence and attack Wu", but in general, medicinal use of the epiphyllum has undergone different ways of concocting, such as black shun slices and white epiphyllum are processed after soaking in the bile bar for a few days and after a long period of time after decoction, and most of the main poisonous components of the raw product, the bis ester-type alkali components, have been hydrolyzed into a second time into the aconite protoine which is a few non-toxicity,. The second aconitine and other components, and on the medicinal properties of the efficacy of a few have no effect, this kind of matching half-summers and other 18 anti-taboo drugs, but also almost no increase in the toxicity of the epiphyllum.

And the concoctions of epiphyllum are salt epiphyllum, cannon epiphyllum, light epiphyllum, etc. These three kinds of concoctions are not boiled for a long time with high temperature, and relatively speaking, they contain more toxic components of bi-ester alkali and mono-ester alkali, which can activate the toxicity of epiphyllum and result in poisoning easily when paired with half-sia and other medicines.

If the concoctions of black shun slices, white appendages are not standardized and too many toxic ingredients are retained, they may also be dispensed to cause a toxic reaction. Moreover, the herb is famous for its eighteen counterparts, and causing poisoning is the responsibility of the prescriber and the blender.

And because of the epiphyllum is a hot product, and smallpox pollen, guayule, Baihe and other herbs cold enough, when used at the same time, if the pairing, the mutual medicinal properties for the offset, the efficacy of the greatly reduced and can not play its own advantages.

The Eighteen Antitheses, first found in Zhang Zihe's "Ru Men Qi Zi", lists three groups of antitheses: licorice against gansui, jingdaji, seaweed, and coriander; aconite (chuanwu, aconite, and caowu) against semixia, gua vulgaris (all gua vulgaris, gua vulgaris peel, gua vulgaris kernel, and smallpox pollen), bei mou (chuanbei and zhebei), bai zhi (white wildflower), and Bai He; and quatrefoil against ginseng, sasanqua (southern and northern), danshen, xuanshen, bitter ginseng, xin xin (fine acne), and paeonia lactiflora (red peony, white peony).

So.What is the date of the book, "Rumen," - the Golden Age.

However, the biggest problem is that in this statement, the aconite is listed and there is no specific mention of the epiphyllum. What is epiphyllum? It's the root of the aconite.

And clinically, there are a lot of formulas where epiphyllum and hemichordon are used together.

Now, the main explanation is that the epiphyllum has been systematically concocted and is much less toxic than aconite. I can't say exactly what the case is. Anyway, it's okay to use epiphyllum with half-sia. Because the eighteen antidotes did not say. Use aconite with is absolutely dare not.

In both ancient and modern times, there are arguments and reports that anti-drug co-administration can produce toxic reactions, and there are also examples of anti-drug co-administration that is not only harmless, but can enhance therapeutic effects.

In modern times, some people have found 85 prescriptions containing 18 antipodes from 10 Qing Dynasty prescription books, which are mainly used for treating difficult and miscellaneous diseases such as carbuncle jaundice, impotence tumor, scrofula, plague, stroke and eclampsia, etc. The national medical master Pu Fu Zhou has also believed that 18 antipodes can cure diseases if they are accurately identified and properly applied. And to the national medical master Pu Fu Zhou, Jiangsu famous doctor Zhu Liangchun and other representatives of the clinic also believe that eighteen anti-drugs if the identification is accurate, the use of appropriate, can indeed cure the disease. Famous old Chinese medicine Gan Zuwang in the "Cocoon Zhai medical words" mentioned his own use of algae experience as "like seaweed and licorice and take the strengthening of its medicinal power, of course, the stomach thin patients, should not be used". There are also some difficult and complicated diseases, such as thyroid diseases, or what is often referred to as "plum nucleus qi", etc., through the clinical diagnosis of the use of seaweed and licorice, have very good curative effects.

In addition, studies have confirmed that whether or not counter-drugs have an opposite effect is related to the proportion of compounding, and that their maintenance at a certain proportion is not harmful, or very harmful, to the human body.

There are actually very few reports of serious toxic reactions to the eighteen antidotes, but in the more than 2,000 years of development of Chinese medicine, the fact that the opposite medicinal properties have not been eliminated and continue to this day lies in the fact that it may reveal the objective law of drug compounding contraindications. The use of antidotes may indeed produce toxic consequences, or it may be the toxicity of the Chinese medicine itself.

As a matter of fact, with the exception of seaweed and licorice, which are not toxic herbs, every other pair of antidotes contains toxic herbs. For example, Glycyrrhiza glabra, Morinda citrifolia, Wuhua, Veratrum, Aconite, and Semen Armeniacae are all toxic herbs to a certain extent. In the course of use, if they are not properly matched or if the dosage is off, they can produce toxic side effects on the human body.

In conclusion, at present, the study of Chinese medicine eighteen against is not comprehensive enough, eighteen against is not an absolute contraindication, and by no means a safe pairing, in the clinical use, need to be based on different individuals, different diseases and carefully choose to use.

Chinese medicine, that is benevolent, wise and wise, depending on what the teacher to teach the ground, but also to see that is what the disciple, more rare is a realization. Enlightenment out of the famous doctors, medicine is also so.

Since the ancient medical doctors clearly put forward eighteen anti-nineteen fear, that these taboos from the practice, so the prudent but also cautious, and these taboos into the Pharmacopoeia, into the Pharmacopoeia on the tip of the legal significance, so you can not fool around. The case of the use of epiphyllum and half-summers together is from "The Essentials of the Golden Chamber", which was also applied by other medical practitioners, and it was only after the Song and Jin dynasties that the eighteen antitheses came into being, which means that they were summarized by the medical practitioners after Zhang Zhongjing. If you search for prescriptions that violate the eighteen countermeasures, almost no one applies them. Violation of the eighteen countermeasures does have side effects, which my colleagues and I have encountered, and we should not be careless. Those who fool people into using medicines indiscriminately are actually doing harm to people.

In addition to the problem of medical skills, experience, and the problem of luck (the problem of luck does not just refer to the doctor luck, but also includes the patient), if one side or both sides of the luck is extremely fierce, then ...... talk about the color of the doctor. In fact, eighteen counter has long been used intentionally or unintentionally, some in order to re-examine, some on the basis of high art and courage to use counter-medicine, some use of counter-medicine they do not realize that (there are problems, there is a crooked to play an accidental role)。 These examples, both intentional and unintentional, show that the use of anti-drugs is not absolute, and that it has something to do with the luck of the doctor and the patient.

This is the eighteen antitheses of the materia medica, that is, there are some drugs that will have the opposite effect, there will be an increase in side effects and toxicity. Such as half piper betel amphibian attack Wu. Wu is the aconite and appendicitis, these are in this category, half Xia, Bei Mu, Gua Pou. These will have side effects with the aconite class, in terms of medication this is a violation of the principle of the use of traditional Chinese medicine. So whoever uses it, whoever bears the legal effect on it, so this is not necessary.

And some people use it no matter when. Produced any adverse consequences he has to bear when the law effect, so clearly give you the provisions that can not be used, the pharmacist will check the medication, the doctor to pay attention to when dispensing, the pharmacist to pay attention to when reviewing the prescription, the pharmacist to review the prescription after the discovery of the opposite drug, will stop prescribing, and then to take the prescription directly and the doctor to proofread the doctor said it is to be used in this way, because of this which some of the pharmacological so to be used in the opposite, the pharmacist Record before prescribing. Then record the dosage. For your review.

And that reasoning makes sense, it's backed up by knowledge, otherwise the pharmacist would be liable for prescribing the drug. So after combining the dosage, here's what it's going to be used for, and this is stated clearly. To be used for its toxicity. Increasing toxicity and side effects to achieve some kind of therapeutic purpose is fine when the dosage is not dangerous. But this has to be signed off on by both parties to establish the principle of treatment. But both would be controversial. So this use of drugs and not magical general for some can cure the disease can be changed some way, and not go this kind of bias because some disease cure are not worth mentioning, the cure is not worth mentioning more, there is no need to go to the bias of the sharp utilitarian. Do this business should abide by the rules of this business. To try to avoid some of the risks of the drug, now the drug is also divided into Category A and Category B is with the toxic side effects to points. So the ancient prescription is toxic. Need a doctor to prescribe, pharmacist review prescription, if you use your own medicine, that is their own responsibility, not the doctor's people to treat you on his commitment to the state of the illegal practice of medicine. So now is the rule of law society drugs are divided into categories, prescription drugs and non-prescription drugs, is well regulated. You want to use to see if you have the right to use, there are symptomatic use in accordance with the amount of use on the line. If you don't have it, don't look for things to do to challenge the rules.

According to pharmacological analysis, eighteen anti mainly refers to the opposite of the medicinal properties, nineteen fear refers to the ability to counteract each other's effectiveness, not necessarily that toxic, the descendants do not understand, fuss, but also served as a forbidden area, scared and dumbfounded.