There is no way to measure this in time, except to say that medicine is always evolving, and so are the drugs for AIDS. Similarly, anti-tumor drugs are also evolving, and the drugs that can actually attack cancer have yet to be researched. Let's talk about some of the drugs currently available for HIV treatment and why HIV treatment is so difficult.

The AIDS virus, or HIV, is an RNA retrovirus that uses viral RNA as a template and produces complementary double-helical DNA catalyzed by a reverse transcriptase enzyme. The viral DNA enters the nucleus of the host cell, and then enters the host's genome under the action of the integrase enzyme. The viral DNA enters the nucleus of the host cell and enters the genome of the host under the action of integrase. It is transcribed and translated into a polyprotein macromolecular nonfunctional polypeptide, which is cleaved by HIV protease into a small functional protein.Therapeutic drugs are also used to fight AIDS by blocking the replication and transformation of the virus according to its reproduction process.

Current anti-AIDS drugs are available:

1. Reverse transcriptase inhibitors :

Nucleoside analogs (zidovudine，Zalcitabine (name)Stavudine, Lamivudine, Desoxynivalenol)

Non-nucleoside reverse transcriptase inhibitors (Denavirdine, Nevirapine, Efavirenz)

2. Protease inhibitors：ritonavir (antiviral drug)Nelfinavir

3. Integrase inhibitors:raltegravir (beta-blocker used in treating asthma)

zidovudine

First Used to treat AIDs Drugs that block the proliferation and replication of the virus, but do not kill it.

Drug of choice for AIDS treatment. Including AIDS and related syndromes (HIV-infected patients with TH lymphocyte count below 300/mm3, weight loss, persistent enlargement of multiple lymph nodes, unexplained fever, etc.), most of the patients' immune indexes and symptoms improve after treatment, and the mortality rate and the rate of opportunistic infections can be reduced. However, repeated use of the drug may produce drug resistance.

brand names include Zeffix, Heptovir, Epivir and Epivir-HBV

There is a synergistic effect in combination with zidovudine. However, it is susceptible to resistance when used alone, and is mainly used in combination with other antiviral agents for the treatment of progressive AIDs.

didanosine

Inhibits HIV replication by directly binding to reverse transcriptase. Synergistic effect when combined with zidovudine.

ritonavir (antiviral drug)

Protease inhibitor that inhibits HIV assembly. Shows strong anti-HIV-1, anti-HIV-2 activity in acutely infected lymphoid stem cells and is also effective against zidovudine-resistant HIV-1.

The combination of protease inhibitors and nucleoside analogs effectively inhibits HIV replication and reduces adverse effects.

raltegravir (beta-blocker used in treating asthma)

Approved by the FDA in 2007, it utilizes the inhibition of integrase to achieve the treatment of AIDS.

Efficacy of existing anti-AIDS virus drugs:

Reducing viral load by suppressing viral replication; delaying the progression of HIV carriers to AIDS and reducing morbidity and mortality; and using"Cocktail" therapyIt interrupts multiple aspects of HIV replication simultaneously, reduces its mutation rate, delays the development of drug resistance, and keeps the patient's viral load low for a longer period of time. Acts at a late stage of infection and has no effect on the process of viral entry into target cells. High adverse effects, 10% of patients die from protease inhibitor-induced heart disease; high cost, "cocktail" therapies cost $20,000 per person per year.

Problems with anti-HIV treatment

Cannot eliminate HIV from the body, need to take medication for a long time, toxic side effects of medication, high cost of medication, drug resistance

At the same time, HIV is an RNA retrovirus that integrates into the human chromosome genome and has no metabolic system of its own, and must rely on the metabolic processes (nucleic acids, proteins, enzymes, etc.) of the host cell for replication to achieve its own growth and reproduction, making research into anti-HIV drugs difficult.

AIDS treatment, a long way to go!

Thanks for the invitation my friend; about how many years will it take to develop a drug that can completely cure AIDS? I can only say that this cannot be determined! If a lot of people don't understand with professional explanations, I will try my best to explain this in a language that the public can understand. I'll start with an example and then get back to the point. First of all, it is important to know that viruses are a very old species, and they are capable of constant mutation and reorganization. Why do some people still get the flu after getting the flu shot? This is because the influenza virus, is constantly mutating, a moment is H5N1 type, a moment and H9N7 type, a moment and then become H3N9 type, ...... a flu vaccine, can only deal with a kind of influenza virus, play a corresponding preventive role. The question arises, then there is no drug that kills the influenza virus? The answer is that there is! But the effect is not very good! After the flu, most people rely on their own immunity to play a role in slowly recovering from the very heavy flu patients, but only to play a symptomatic treatment of the auxiliary role. The word back to the main topic! HIV invasion into the human body, hosted in the nucleus of the human body, if there is a drug can kill the AIDS virus, without damaging the nucleus of the human cell, is almost an impossible thing to accomplish! It is a medicine that is three times poisonous, kills a thousand and damages eight hundred, HIV is eliminated, and human cells are also subjected to a great deal of damage! Pharmacologists also know this problem, and what they are trying to do is to eliminate HIV, and the damage to human cells is reduced to a minimum. It's a dilemma; it's not quite possible to want the horse to run and not eat the grass at the same time. Until a preventive vaccine for AIDS is developed, pharmacologists will have to work tirelessly to develop new drugs. The road is high, the devil is high, not waiting for your drug development, HIV reorganization and mutation! The reason why AIDS patients get good results with drugs in the early stages, but not so much in the later stages, is because the HIV virus develops drug-resistant mutations, and the virus reorganizes again! It can be said that the complete development of drugs to eliminate AIDS, will continue, unless there is a major invention progress, biochemical recombination technology is the most promising, can be genetically recombined through stem cells, biotechnology to deal with HIV, from this aspect of the breakthrough of a new way to this is going to take a very long time, it is really not good to say! Therefore, we still have to keep ourselves clean and do not go out to have sex! We all know the three ways of spreading AIDS, so I won't talk about it here.

There is no definitive time frame for exactly how long it will take for AIDS treatment drugs to be researched. Developing drugs is a process just like technological development. But nowadays there is something called cocktail therapy, which is a method of combining many drugs together.

AIDS is not scary, some have a long incubation period, as long as daily life pay attention to the complications can be like a normal person to live to old age!

No one in the world can accurately tell you this question at this time, it's better to do the right thing and take precautions.

Thanks: I can't give you an exact time frame for this question.

Science and technology research is not like building a house that you can build in a few years if you say you can. It depends on luck.

How do you say that it depends on luck? Because there are things that are very difficult to research, some scientific research projects researchers spend their whole life can not break through, not that tomorrow I can develop a successful success will be successful. You can find nowadays many scientific research achievements are researchers in the accidental discovery or research for a long time, due to other factors and success.